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PBYIPuma Biotechnology, Inc.
$6.38
Financials
BUY
Analysis updated: Jan 16, 2026

Investment Thesis

PBYI is in the high-probability buy zone: RS 89/99 (Top 11%), TEXTBOOK VCP pattern, STRONG earnings. High-probability trade. Execute with discipline - honor your stop loss.

Key Takeaways

Earnings Momentum

+50%
Q4'24
$0.39
+160%
Q1'25
$0.06
+228%
Q2'25
$0.12
-59%
Q3'25
$0.17
Earnings Growing

Price Structure

Aligned Uptrend
Price
$6.38
✓
→
50 DMA
$5.51
✓
→
100 DMA
$5.26
✓
→
150 DMA
$4.75
✓
→
200 DMA
$4.35
Alignment Score: 4/4✓ Confirmed Uptrend

PBYI Price Chart

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50 DMA150 DMA200 DMA

Twin Engines Dashboard

Technical Health

RS Rating
89/99
Top 11% ✓
Trend
Aligned Uptrend
Above 200 DMA
RSI (14)
67
BULLISH
VCP Setup
HOT
Score: 8/9
Volume
291K
-40% vs avg
From Entry
+3.6%
$6.16

Fundamental Horsepower

EPS Qtr YoY
-59%
Declining
EPS 3Y CAGR
N/A
Annual Earnings
Revenue Qtr
-32%
DECLINING
F-Score
6/9
Piotroski Quality
ROE
42%
Return on Equity
EPS Rank
73/99
Percentile

Trade Plan

Running

Broke out 3 weeks ago — now +3.6% from entry.

Trail stop at $6.16 (21 EMA or entry). Add on pullback to $6.19 - $6.00 (10-21 EMA).

Breakout Date2025-12-2621 days ago
Entry Price$6.16+3.6% since
Pullback Zone$6.19 - $6.00 (10-21 EMA)Re-entry levels
Trail Stop$6.16Breakeven or 21 EMA
Breakout Quality5/10Normal volume

If/Then Playbook

IF: Price pulls back to 10/21 EMA zone
THEN: Consider adding with tight stop below 21 EMA
IF: Price closes below $5.73
THEN: SELL immediately, no questions asked
IF: Price reaches $7.08 (+15%)
THEN: Lock in 1/3 profits, raise stop to breakeven
IF: Price reaches $7.70 (+25%)
THEN: Lock in another 1/3, trail stop at 10 EMA
IF: Volume dries up after breakout
THEN: Tighten stop - potential failed breakout

Key Price Levels

Resistance

  • 52W High$6.46+1.3%
  • Pivot$6.46+1.3%
Current$6.38

Support

  • 20 DMA$6.00-5.9%
  • 50 DMA$5.51-13.6%
  • 200 DMA$4.35-31.8%

More PBYI Analysis

Fundamental Analysis →Intrinsic Value →Total Return Calculator →

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Frequently Asked Questions

Is PBYI stock a buy now?

PBYI is in the high-probability buy zone: RS 89/99 (Top 11%), TEXTBOOK VCP pattern, STRONG earnings. High-probability trade. Execute with discipline - honor your stop loss.

What is the buy point for PBYI?

PBYI broke out at $6.16 recently and is up 3.6%. Still early - monitor for follow-through confirmation.

What is PBYI's RS Rating?

PBYI has an RS Rating of 89/99, meaning it's in the Top 11% of all stocks for relative price performance over the past 12 months. Minervini recommends RS 80+ for momentum trades.

Important Disclosure: This analysis is for educational and informational purposes only. Technical and fundamental indicators are based on historical data and do not guarantee future performance. Past performance is not indicative of future results. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.