Comprehensive Stock Comparison
Compare ADMA Biologics, Inc. (ADMA) vs Regeneron Pharmaceuticals, Inc. (REGN) Stock
Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.
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Quick Verdict
| Category | Winner | Why |
|---|---|---|
| Growth | ADMA | 65.2% revenue growth vs REGN's 1.0% |
| Value | ADMA | Lower P/E (16.3x vs 17.3x) |
| Quality / Margins | ADMA | 42.9% net margin vs REGN's 31.4% |
| Stability / Safety | REGN | Beta 0.58 vs ADMA's 1.10, lower leverage |
| Dividends | REGN | 0.4% yield; 1-year raise streak; ADMA pays no meaningful dividend |
| Momentum (1Y) | REGN | +12.4% vs ADMA's -5.0% |
| Efficiency (ROA) | ADMA | 36.8% ROA vs REGN's 11.1%, ROIC 37.7% vs 12.4% |
Who Each Stock Is For
Income & stability
Growth exposure
Long-term compounding (10Y)
Sleep-well-at-night portfolio
Defensive / Recession hedge
Business Model
What each company does and how it makes money
ADMA Biologics is a biopharmaceutical company that develops, manufactures, and markets specialty plasma-derived biologics for treating immune deficiencies and infectious diseases. It generates revenue primarily from sales of its intravenous immune globulin products — BIVIGAM and ASCENIV — along with its Hepatitis B treatment Nabi-HB, while also operating plasma collection facilities. The company's key advantage is its integrated business model that combines plasma collection, manufacturing, and commercialization, creating a vertically controlled supply chain for plasma-derived therapies.
Regeneron Pharmaceuticals is a biotechnology company that discovers, develops, and commercializes innovative medicines for serious diseases. It generates revenue primarily from sales of its flagship products — EYLEA for eye diseases (~60% of revenue) and Dupixent for inflammatory conditions (~30%) — with additional income from collaborations and royalties. The company's competitive advantage lies in its proprietary VelocImmune technology platform for creating human antibodies and its deep expertise in genetic research, which enables rapid drug discovery and development.
Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Financial Metrics Comparison
Side-by-side fundamentals across 2 stocks. BestLagging
Financial Scorecard
ADMA leads in 3 of 6 categories (Financial Metrics, Profitability & Efficiency). REGN leads in 2 (Valuation Metrics, Risk & Volatility).
Financial Metrics (TTM)
REGN is the larger business by revenue, generating $14.3B annually — 29.4x ADMA's $489M. ADMA is the more profitable business, keeping 42.9% of every revenue dollar as net income compared to REGN's 31.4%. On growth, ADMA holds the edge at +12.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ADMAADMA Biologics, I… | REGNRegeneron Pharmac… |
|---|---|---|
| RevenueTrailing 12 months | $489M | $14.3B |
| EBITDAEarnings before interest/tax | $175M | $4.2B |
| Net IncomeAfter-tax profit | $209M | $4.5B |
| Free Cash FlowCash after capex | $41M | $3.2B |
| Gross MarginGross profit ÷ Revenue | +54.7% | +86.3% |
| Operating MarginEBIT ÷ Revenue | +34.2% | +25.7% |
| Net MarginNet income ÷ Revenue | +42.9% | +31.4% |
| FCF MarginFCF ÷ Revenue | +8.3% | +22.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +12.0% | +2.5% |
| EPS Growth (YoY)Latest quarter vs prior year | 0.0% | -2.5% |
Valuation Metrics
At 18.8x trailing earnings, REGN trades at a 2% valuation discount to ADMA's 19.2x P/E. On an enterprise value basis, REGN's 21.6x EV/EBITDA is more attractive than ADMA's 25.1x.
| Metric | ADMAADMA Biologics, I… | REGNRegeneron Pharmac… |
|---|---|---|
| Market CapShares × price | $3.7B | $107.6B |
| Enterprise ValueMkt cap + debt − cash | $3.7B | $91.4B |
| Trailing P/EPrice ÷ TTM EPS | 19.22x | 18.84x |
| Forward P/EPrice ÷ next-FY EPS est. | 16.30x | 17.25x |
| PEG RatioP/E ÷ EPS growth rate | — | 2.98x |
| EV / EBITDAEnterprise value multiple | 25.10x | 21.64x |
| Price / SalesMarket cap ÷ Revenue | 8.70x | 7.50x |
| Price / BookPrice ÷ Book value/share | 10.86x | 2.72x |
| Price / FCFMarket cap ÷ FCF | 33.71x | 26.36x |
Profitability & Efficiency
ADMA delivers a 48.6% return on equity — every $100 of shareholder capital generates $49 in annual profit, vs $14 for REGN. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to ADMA's 0.24x.
| Metric | ADMAADMA Biologics, I… | REGNRegeneron Pharmac… |
|---|---|---|
| ROE (TTM)Return on equity | +48.6% | +14.4% |
| ROA (TTM)Return on assets | +36.8% | +11.1% |
| ROICReturn on invested capital | +37.7% | +12.4% |
| ROCEReturn on capital employed | +39.0% | +10.8% |
| Piotroski ScoreFundamental quality 0–9 | 7 | 7 |
| Debt / EquityFinancial leverage | 0.24x | 0.09x |
| Net DebtTotal debt minus cash | -$21M | -$16.2B |
| Cash & Equiv.Liquid assets | $103M | $18.9B |
| Total DebtShort + long-term debt | $82M | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | 19.63x | 120.42x |
Total Returns (with DRIP)
A $10,000 investment in ADMA five years ago would be worth $64,339 today (with dividends reinvested), compared to $16,977 for REGN. Over the past 12 months, REGN leads with a +12.4% total return vs ADMA's -5.0%. The 3-year compound annual growth rate (CAGR) favors ADMA at 63.7% vs REGN's 1.1% — a key indicator of consistent wealth creation.
| Metric | ADMAADMA Biologics, I… | REGNRegeneron Pharmac… |
|---|---|---|
| YTD ReturnYear-to-date | -12.9% | +0.8% |
| 1-Year ReturnPast 12 months | -5.0% | +12.4% |
| 3-Year ReturnCumulative with dividends | +338.6% | +3.4% |
| 5-Year ReturnCumulative with dividends | +543.4% | +69.8% |
| 10-Year ReturnCumulative with dividends | +227.8% | +104.7% |
| CAGR (3Y)Annualised 3-year return | +63.7% | +1.1% |
Risk & Volatility
REGN is the less volatile stock with a 0.58 beta — it tends to amplify market swings less than ADMA's 1.10 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. REGN currently trades 95.2% from its 52-week high vs ADMA's 60.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ADMAADMA Biologics, I… | REGNRegeneron Pharmac… |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.10x | 0.58x |
| 52-Week HighHighest price in past year | $25.67 | $821.11 |
| 52-Week LowLowest price in past year | $13.50 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +60.7% | +95.2% |
| RSI (14)Momentum oscillator 0–100 | 35.7 | 49.1 |
| Avg Volume (50D)Average daily shares traded | 1.8M | 687K |
Analyst Outlook
Wall Street rates ADMA as "Buy" and REGN as "Buy". Consensus price targets imply 9.7% upside for REGN (target: $857) vs 2.8% for ADMA (target: $16). REGN is the only dividend payer here at 0.44% yield — a key consideration for income-focused portfolios.
| Metric | ADMAADMA Biologics, I… | REGNRegeneron Pharmac… |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $16.00 | $857.17 |
| # AnalystsCovering analysts | 9 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +0.4% |
| Dividend StreakConsecutive years of raises | 1 | 1 |
| Dividend / ShareAnnual DPS | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +3.2% |
Historical Charts
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Chart 1Total Return — 5 Years (Rebased to 100)
| Stock | Mar 20 | Feb 26 | Change |
|---|---|---|---|
| ADMA Biologics, Inc. (ADMA) | 100 | 589.23 | +489.2% |
| Regeneron Pharmaceu… (REGN) | 100 | 162.46 | +62.5% |
ADMA Biologics, Inc. (ADMA) returned +543% over 5 years vs Regeneron Pharmaceu… (REGN)'s +70%. A $10,000 investment in ADMA 5 years ago would be worth $64,339 today (including dividends reinvested).
Chart 2Revenue Growth — 10 Years
| Stock | 2016 | 2025 | Change |
|---|---|---|---|
| ADMA Biologics, Inc. (ADMA) | $11M | $426M | +3900.1% |
| Regeneron Pharmaceu… (REGN) | $4.9B | $14.3B | +195.1% |
Regeneron Pharmaceuticals, Inc.'s revenue grew from $4.9B (2016) to $14.3B (2025) — a 12.8% CAGR.
Chart 3Net Margin Trend — 10 Years
| Stock | 2016 | 2025 | Change |
|---|---|---|---|
| ADMA Biologics, Inc. (ADMA) | -183.1% | 46.4% | +125.3% |
| Regeneron Pharmaceu… (REGN) | 18.4% | 31.4% | +70.5% |
Regeneron Pharmaceuticals, Inc.'s net margin went from 18% (2016) to 31% (2025).
Chart 4P/E Ratio History — 9 Years
| Stock | 2017 | 2025 | Change |
|---|---|---|---|
| Regeneron Pharmaceu… (REGN) | 36.4 | 18.6 | -48.9% |
Regeneron Pharmaceuticals, Inc. has traded in a 9x–36x P/E range over 9 years; current trailing P/E is ~19x.
Chart 5EPS Growth — 10 Years
| Stock | 2016 | 2025 | Change |
|---|---|---|---|
| ADMA Biologics, Inc. (ADMA) | -1.61 | 0.81 | +150.3% |
| Regeneron Pharmaceu… (REGN) | 7.7 | 41.48 | +438.7% |
Regeneron Pharmaceuticals, Inc.'s EPS grew from $7.70 (2016) to $41.48 (2025) — a 21% CAGR.
Chart 6Free Cash Flow — 5 Years
ADMA Biologics, Inc. generated $110M FCF in 2024 (+187% vs 2021). Regeneron Pharmaceuticals, Inc. generated $4B FCF in 2025 (-38% vs 2021).
ADMA vs REGN: Frequently Asked Questions
9 questions · data-driven answers · updated daily
01Is ADMA or REGN a better buy right now?
Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 18.8x trailing P/E (17.3x forward), making it the more compelling value choice. Analysts rate ADMA Biologics, Inc. (ADMA) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ADMA or REGN?
On trailing P/E, Regeneron Pharmaceuticals, Inc. (REGN) is the cheapest at 18.8x versus ADMA Biologics, Inc. at 19.2x. On forward P/E, ADMA Biologics, Inc. is actually cheaper at 16.3x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — ADMA or REGN?
Over the past 5 years, ADMA Biologics, Inc. (ADMA) delivered a total return of +543.4%, compared to +69.8% for Regeneron Pharmaceuticals, Inc. (REGN). A $10,000 investment in ADMA five years ago would be worth approximately $64K today (assuming dividends reinvested). Over 10 years, the gap is even starker: ADMA returned +227.8% versus REGN's +104.7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ADMA or REGN?
By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc. (REGN) is the lower-risk stock at 0.58β versus ADMA Biologics, Inc.'s 1.10β — meaning ADMA is approximately 91% more volatile than REGN relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 24% for ADMA Biologics, Inc. — giving it more financial flexibility in a downturn.
05Which has better profit margins — ADMA or REGN?
ADMA Biologics, Inc. (ADMA) is the more profitable company, earning 46.4% net margin versus 31.4% for Regeneron Pharmaceuticals, Inc. — meaning it keeps 46.4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADMA leads at 32.6% versus 25.7% for REGN. At the gross margin level — before operating expenses — REGN leads at 86.3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is ADMA or REGN more undervalued right now?
On forward earnings alone, ADMA Biologics, Inc. (ADMA) trades at 16.3x forward P/E versus 17.3x for Regeneron Pharmaceuticals, Inc. — 0.9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for REGN: 9.7% to $857.17.
07Which pays a better dividend — ADMA or REGN?
In this comparison, REGN (0.4% yield) pays a dividend. ADMA does not pay a meaningful dividend and should not be held primarily for income.
08Is ADMA or REGN better for a retirement portfolio?
For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc. (REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.58), +104.7% 10Y return). Both have compounded well over 10 years (REGN: +104.7%, ADMA: +227.8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between ADMA and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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