Comprehensive Stock Comparison

Compare Genmab A/S (GMAB) vs Regeneron Pharmaceuticals, Inc. (REGN) Stock

Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.

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Quick Verdict

CategoryWinnerWhy
GrowthGMAB30.7% revenue growth vs REGN's 1.0%
ValueGMABPEG 0.80 vs 2.73
Quality / MarginsGMAB46.8% net margin vs REGN's 31.4%
Stability / SafetyREGNBeta 0.58 vs GMAB's 0.61
DividendsREGN0.4% yield; 1-year raise streak; GMAB pays no meaningful dividend
Momentum (1Y)GMAB+29.8% vs REGN's +12.4%
Efficiency (ROA)GMAB93.6% ROA vs REGN's 11.1%, ROIC 22.2% vs 12.4%
Bottom line: GMAB leads in 5 of 7 categories, making it the stronger pick for investors who prioritize growth and revenue expansion and valuation and capital efficiency. Regeneron Pharmaceuticals, Inc. is the better choice for capital preservation and lower volatility and dividend income and shareholder returns. As direct sector peers, they can serve as alternatives in the same portfolio allocation.

Who Each Stock Is For

Income & stability

Growth exposure

Long-term compounding (10Y)

Sleep-well-at-night portfolio

Valuation efficiency (growth/$)

Defensive / Recession hedge

Business Model

What each company does and how it makes money

GMABGenmab A/S
Healthcare

Genmab is a biotechnology company that develops and commercializes antibody-based therapies for cancer and other serious diseases. It generates revenue primarily through product sales of its marketed antibodies like DARZALEX and teprotumumab, plus significant royalties and milestone payments from partnerships with pharmaceutical companies like Johnson & Johnson. The company's key advantage is its proprietary antibody technology platforms — particularly its DuoBody bispecific antibody platform — which enable it to create differentiated therapies with improved efficacy and safety profiles.

REGNRegeneron Pharmaceuticals, Inc.
Healthcare

Regeneron Pharmaceuticals is a biotechnology company that discovers, develops, and commercializes innovative medicines for serious diseases. It generates revenue primarily from sales of its flagship products — EYLEA for eye diseases (~60% of revenue) and Dupixent for inflammatory conditions (~30%) — with additional income from collaborations and royalties. The company's competitive advantage lies in its proprietary VelocImmune technology platform for creating human antibodies and its deep expertise in genetic research, which enables rapid drug discovery and development.

Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

GMABGenmab A/S

Segment breakdown not available.

REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M

Financial Metrics Comparison

Side-by-side fundamentals across 2 stocks. BestLagging

Financial Scorecard

GMAB 2REGN 2
Financial MetricsTie3/6 metrics
Valuation MetricsGMAB5/7 metrics
Profitability & EfficiencyGMAB6/9 metrics
Total ReturnsREGN4/6 metrics
Risk & VolatilityREGN2/2 metrics
Analyst Outlook0/0 metrics

GMAB leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). REGN leads in 2 (Total Returns, Risk & Volatility). 1 tied.

Financial Metrics (TTM)

REGN and GMAB operate at a comparable scale, with $14.3B and $14.0B in trailing revenue. GMAB is the more profitable business, keeping 46.8% of every revenue dollar as net income compared to REGN's 31.4%. On growth, REGN holds the edge at +2.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricGMABGenmab A/SREGNRegeneron Pharmac…
RevenueTrailing 12 months$14.0B$14.3B
EBITDAEarnings before interest/tax$5.3B$4.2B
Net IncomeAfter-tax profit$6.6B$4.5B
Free Cash FlowCash after capex$2.9B$3.2B
Gross MarginGross profit ÷ Revenue+94.3%+86.3%
Operating MarginEBIT ÷ Revenue+36.2%+25.7%
Net MarginNet income ÷ Revenue+46.8%+31.4%
FCF MarginFCF ÷ Revenue+20.7%+22.0%
Rev. Growth (YoY)Latest quarter vs prior year-81.6%+2.5%
EPS Growth (YoY)Latest quarter vs prior year-66.7%-2.5%
Evenly matched — GMAB and REGN each lead in 3 of 6 comparable metrics.

Valuation Metrics

At 15.4x trailing earnings, GMAB trades at a 18% valuation discount to REGN's 18.8x P/E. Adjusting for growth (PEG ratio), GMAB offers better value at 0.53x vs REGN's 2.98x — a lower PEG means you pay less per unit of expected earnings growth.

MetricGMABGenmab A/SREGNRegeneron Pharmac…
Market CapShares × price$18.1B$107.6B
Enterprise ValueMkt cap + debt − cash$16.7B$91.4B
Trailing P/EPrice ÷ TTM EPS15.36x18.84x
Forward P/EPrice ÷ next-FY EPS est.23.15x17.25x
PEG RatioP/E ÷ EPS growth rate0.53x2.98x
EV / EBITDAEnterprise value multiple14.90x21.64x
Price / SalesMarket cap ÷ Revenue5.34x7.50x
Price / BookPrice ÷ Book value/share3.28x2.72x
Price / FCFMarket cap ÷ FCF15.15x26.36x
GMAB leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

GMAB delivers a 114.2% return on equity — every $100 of shareholder capital generates $114 in annual profit, vs $14 for REGN. GMAB carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to REGN's 0.09x. On the Piotroski fundamental quality scale (0–9), REGN scores 7/9 vs GMAB's 5/9, reflecting strong financial health.

MetricGMABGenmab A/SREGNRegeneron Pharmac…
ROE (TTM)Return on equity+114.2%+14.4%
ROA (TTM)Return on assets+93.6%+11.1%
ROICReturn on invested capital+22.2%+12.4%
ROCEReturn on capital employed+18.3%+10.8%
Piotroski ScoreFundamental quality 0–957
Debt / EquityFinancial leverage0.03x0.09x
Net DebtTotal debt minus cash-$8.8B-$16.2B
Cash & Equiv.Liquid assets$9.9B$18.9B
Total DebtShort + long-term debt$1.0B$2.7B
Interest CoverageEBIT ÷ Interest expense48.21x120.42x
GMAB leads this category, winning 6 of 9 comparable metrics.

Total Returns (with DRIP)

A $10,000 investment in REGN five years ago would be worth $16,977 today (with dividends reinvested), compared to $8,383 for GMAB. Over the past 12 months, GMAB leads with a +29.8% total return vs REGN's +12.4%. The 3-year compound annual growth rate (CAGR) favors REGN at 1.1% vs GMAB's -7.8% — a key indicator of consistent wealth creation.

MetricGMABGenmab A/SREGNRegeneron Pharmac…
YTD ReturnYear-to-date-7.5%+0.8%
1-Year ReturnPast 12 months+29.8%+12.4%
3-Year ReturnCumulative with dividends-21.6%+3.4%
5-Year ReturnCumulative with dividends-16.2%+69.8%
10-Year ReturnCumulative with dividends+138.4%+104.7%
CAGR (3Y)Annualised 3-year return-7.8%+1.1%
REGN leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

REGN is the less volatile stock with a 0.58 beta — it tends to amplify market swings less than GMAB's 0.61 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. REGN currently trades 95.2% from its 52-week high vs GMAB's 83.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricGMABGenmab A/SREGNRegeneron Pharmac…
Beta (5Y)Sensitivity to S&P 5000.61x0.58x
52-Week HighHighest price in past year$35.43$821.11
52-Week LowLowest price in past year$17.24$476.49
% of 52W HighCurrent price vs 52-week peak+83.1%+95.2%
RSI (14)Momentum oscillator 0–10038.349.1
Avg Volume (50D)Average daily shares traded1.5M687K
REGN leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Wall Street rates GMAB as "Buy" and REGN as "Buy". Consensus price targets imply 37.6% upside for GMAB (target: $41) vs 9.7% for REGN (target: $857). REGN is the only dividend payer here at 0.44% yield — a key consideration for income-focused portfolios.

MetricGMABGenmab A/SREGNRegeneron Pharmac…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$40.50$857.17
# AnalystsCovering analysts1748
Dividend YieldAnnual dividend ÷ price+0.4%
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS$3.41
Buyback YieldShare repurchases ÷ mkt cap+3.5%+3.2%
Insufficient data to determine a leader in this category.

Historical Charts

Charts are rendered on first load. Hover for details.

Chart 1Total Return — 5 Years (Rebased to 100)

StockMar 20Feb 26Change
Genmab A/S (GMAB)100138.39+38.4%
Regeneron Pharmaceu… (REGN)100162.46+62.5%

Regeneron Pharmaceu… (REGN) returned +70% over 5 years vs Genmab A/S (GMAB)'s -16%. A $10,000 investment in REGN 5 years ago would be worth $16,977 today (including dividends reinvested).

Chart 2Revenue Growth — 10 Years

Stock20162025Change
Genmab A/S (GMAB)$1.8B$21.5B+1085.3%
Regeneron Pharmaceu… (REGN)$4.9B$14.3B+195.1%

Regeneron Pharmaceuticals, Inc.'s revenue grew from $4.9B (2016) to $14.3B (2025) — a 12.8% CAGR.

Chart 3Net Margin Trend — 10 Years

Stock20162025Change
Genmab A/S (GMAB)65.4%36.4%-44.3%
Regeneron Pharmaceu… (REGN)18.4%31.4%+70.5%

Regeneron Pharmaceuticals, Inc.'s net margin went from 18% (2016) to 31% (2025).

Chart 4P/E Ratio History — 9 Years

Stock20172025Change
Genmab A/S (GMAB)9.31.7-81.7%
Regeneron Pharmaceu… (REGN)36.418.6-48.9%

Genmab A/S has traded in a 2x–9x P/E range over 8 years; current trailing P/E is ~15x. Regeneron Pharmaceuticals, Inc. has traded in a 9x–36x P/E range over 9 years; current trailing P/E is ~19x.

Chart 5EPS Growth — 10 Years

Stock20162025Change
Genmab A/S (GMAB)1.9212.14+532.3%
Regeneron Pharmaceu… (REGN)7.741.48+438.7%

Regeneron Pharmaceuticals, Inc.'s EPS grew from $7.70 (2016) to $41.48 (2025) — a 21% CAGR.

Chart 6Free Cash Flow — 5 Years

2021
$2B
$7B
2022
$4B
$4B
2023
$7B
$4B
2024
$8B
$4B
2025
$4B
Genmab A/S (GMAB)Regeneron Pharmaceu… (REGN)

Genmab A/S generated $8B FCF in 2024 (+284% vs 2021). Regeneron Pharmaceuticals, Inc. generated $4B FCF in 2025 (-38% vs 2021).

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GMAB vs REGN: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is GMAB or REGN a better buy right now?

Genmab A/S (GMAB) offers the better valuation at 15.4x trailing P/E (23.2x forward), making it the more compelling value choice. Analysts rate Genmab A/S (GMAB) a "Buy" — based on 17 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — GMAB or REGN?

On trailing P/E, Genmab A/S (GMAB) is the cheapest at 15.4x versus Regeneron Pharmaceuticals, Inc. at 18.8x. On forward P/E, Regeneron Pharmaceuticals, Inc. is actually cheaper at 17.3x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Genmab A/S wins at 0.80x versus Regeneron Pharmaceuticals, Inc.'s 2.73x — a PEG below 1.0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — GMAB or REGN?

Over the past 5 years, Regeneron Pharmaceuticals, Inc. (REGN) delivered a total return of +69.8%, compared to -16.2% for Genmab A/S (GMAB). A $10,000 investment in REGN five years ago would be worth approximately $17K today (assuming dividends reinvested). Over 10 years, the gap is even starker: GMAB returned +138.4% versus REGN's +104.7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — GMAB or REGN?

By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc. (REGN) is the lower-risk stock at 0.58β versus Genmab A/S's 0.61β — meaning GMAB is approximately 6% more volatile than REGN relative to the S&P 500. On balance sheet safety, Genmab A/S (GMAB) carries a lower debt/equity ratio of 3% versus 9% for Regeneron Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

05

Which has better profit margins — GMAB or REGN?

Genmab A/S (GMAB) is the more profitable company, earning 36.4% net margin versus 31.4% for Regeneron Pharmaceuticals, Inc. — meaning it keeps 36.4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: GMAB leads at 31.1% versus 25.7% for REGN. At the gross margin level — before operating expenses — GMAB leads at 95.4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is GMAB or REGN more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential. By this metric, Genmab A/S (GMAB) is the more undervalued stock at a PEG of 0.80x versus Regeneron Pharmaceuticals, Inc.'s 2.73x. A PEG below 1.0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Regeneron Pharmaceuticals, Inc. (REGN) trades at 17.3x forward P/E versus 23.2x for Genmab A/S — 5.9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for GMAB: 37.6% to $40.50.

07

Which pays a better dividend — GMAB or REGN?

In this comparison, REGN (0.4% yield) pays a dividend. GMAB does not pay a meaningful dividend and should not be held primarily for income.

08

Is GMAB or REGN better for a retirement portfolio?

For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc. (REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.58), +104.7% 10Y return). Both have compounded well over 10 years (REGN: +104.7%, GMAB: +138.4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between GMAB and REGN?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. In terms of investment character: GMAB is a mid-cap deep-value stock; REGN is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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GMAB

Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 28%
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REGN

Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 18%
  • Dividend Yield > 0.5%
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Better Than Both

Find stocks that beat GMAB and REGN on the metrics you choose

Revenue Growth>
%
(GMAB: -81.6% · REGN: 2.5%)
Net Margin>
%
(GMAB: 46.8% · REGN: 31.4%)
P/E Ratio<
x
(GMAB: 15.4x · REGN: 18.8x)