Comprehensive Stock Comparison
Compare Genmab A/S (GMAB) vs Regeneron Pharmaceuticals, Inc. (REGN) Stock
Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.
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Quick Verdict
| Category | Winner | Why |
|---|---|---|
| Growth | GMAB | 30.7% revenue growth vs REGN's 1.0% |
| Value | GMAB | PEG 0.80 vs 2.73 |
| Quality / Margins | GMAB | 46.8% net margin vs REGN's 31.4% |
| Stability / Safety | REGN | Beta 0.58 vs GMAB's 0.61 |
| Dividends | REGN | 0.4% yield; 1-year raise streak; GMAB pays no meaningful dividend |
| Momentum (1Y) | GMAB | +29.8% vs REGN's +12.4% |
| Efficiency (ROA) | GMAB | 93.6% ROA vs REGN's 11.1%, ROIC 22.2% vs 12.4% |
Who Each Stock Is For
Income & stability
Growth exposure
Long-term compounding (10Y)
Sleep-well-at-night portfolio
Valuation efficiency (growth/$)
Defensive / Recession hedge
Business Model
What each company does and how it makes money
Genmab is a biotechnology company that develops and commercializes antibody-based therapies for cancer and other serious diseases. It generates revenue primarily through product sales of its marketed antibodies like DARZALEX and teprotumumab, plus significant royalties and milestone payments from partnerships with pharmaceutical companies like Johnson & Johnson. The company's key advantage is its proprietary antibody technology platforms — particularly its DuoBody bispecific antibody platform — which enable it to create differentiated therapies with improved efficacy and safety profiles.
Regeneron Pharmaceuticals is a biotechnology company that discovers, develops, and commercializes innovative medicines for serious diseases. It generates revenue primarily from sales of its flagship products — EYLEA for eye diseases (~60% of revenue) and Dupixent for inflammatory conditions (~30%) — with additional income from collaborations and royalties. The company's competitive advantage lies in its proprietary VelocImmune technology platform for creating human antibodies and its deep expertise in genetic research, which enables rapid drug discovery and development.
Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Financial Metrics Comparison
Side-by-side fundamentals across 2 stocks. BestLagging
Financial Scorecard
GMAB leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). REGN leads in 2 (Total Returns, Risk & Volatility). 1 tied.
Financial Metrics (TTM)
REGN and GMAB operate at a comparable scale, with $14.3B and $14.0B in trailing revenue. GMAB is the more profitable business, keeping 46.8% of every revenue dollar as net income compared to REGN's 31.4%. On growth, REGN holds the edge at +2.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | GMABGenmab A/S | REGNRegeneron Pharmac… |
|---|---|---|
| RevenueTrailing 12 months | $14.0B | $14.3B |
| EBITDAEarnings before interest/tax | $5.3B | $4.2B |
| Net IncomeAfter-tax profit | $6.6B | $4.5B |
| Free Cash FlowCash after capex | $2.9B | $3.2B |
| Gross MarginGross profit ÷ Revenue | +94.3% | +86.3% |
| Operating MarginEBIT ÷ Revenue | +36.2% | +25.7% |
| Net MarginNet income ÷ Revenue | +46.8% | +31.4% |
| FCF MarginFCF ÷ Revenue | +20.7% | +22.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | -81.6% | +2.5% |
| EPS Growth (YoY)Latest quarter vs prior year | -66.7% | -2.5% |
Valuation Metrics
At 15.4x trailing earnings, GMAB trades at a 18% valuation discount to REGN's 18.8x P/E. Adjusting for growth (PEG ratio), GMAB offers better value at 0.53x vs REGN's 2.98x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | GMABGenmab A/S | REGNRegeneron Pharmac… |
|---|---|---|
| Market CapShares × price | $18.1B | $107.6B |
| Enterprise ValueMkt cap + debt − cash | $16.7B | $91.4B |
| Trailing P/EPrice ÷ TTM EPS | 15.36x | 18.84x |
| Forward P/EPrice ÷ next-FY EPS est. | 23.15x | 17.25x |
| PEG RatioP/E ÷ EPS growth rate | 0.53x | 2.98x |
| EV / EBITDAEnterprise value multiple | 14.90x | 21.64x |
| Price / SalesMarket cap ÷ Revenue | 5.34x | 7.50x |
| Price / BookPrice ÷ Book value/share | 3.28x | 2.72x |
| Price / FCFMarket cap ÷ FCF | 15.15x | 26.36x |
Profitability & Efficiency
GMAB delivers a 114.2% return on equity — every $100 of shareholder capital generates $114 in annual profit, vs $14 for REGN. GMAB carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to REGN's 0.09x. On the Piotroski fundamental quality scale (0–9), REGN scores 7/9 vs GMAB's 5/9, reflecting strong financial health.
| Metric | GMABGenmab A/S | REGNRegeneron Pharmac… |
|---|---|---|
| ROE (TTM)Return on equity | +114.2% | +14.4% |
| ROA (TTM)Return on assets | +93.6% | +11.1% |
| ROICReturn on invested capital | +22.2% | +12.4% |
| ROCEReturn on capital employed | +18.3% | +10.8% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 7 |
| Debt / EquityFinancial leverage | 0.03x | 0.09x |
| Net DebtTotal debt minus cash | -$8.8B | -$16.2B |
| Cash & Equiv.Liquid assets | $9.9B | $18.9B |
| Total DebtShort + long-term debt | $1.0B | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | 48.21x | 120.42x |
Total Returns (with DRIP)
A $10,000 investment in REGN five years ago would be worth $16,977 today (with dividends reinvested), compared to $8,383 for GMAB. Over the past 12 months, GMAB leads with a +29.8% total return vs REGN's +12.4%. The 3-year compound annual growth rate (CAGR) favors REGN at 1.1% vs GMAB's -7.8% — a key indicator of consistent wealth creation.
| Metric | GMABGenmab A/S | REGNRegeneron Pharmac… |
|---|---|---|
| YTD ReturnYear-to-date | -7.5% | +0.8% |
| 1-Year ReturnPast 12 months | +29.8% | +12.4% |
| 3-Year ReturnCumulative with dividends | -21.6% | +3.4% |
| 5-Year ReturnCumulative with dividends | -16.2% | +69.8% |
| 10-Year ReturnCumulative with dividends | +138.4% | +104.7% |
| CAGR (3Y)Annualised 3-year return | -7.8% | +1.1% |
Risk & Volatility
REGN is the less volatile stock with a 0.58 beta — it tends to amplify market swings less than GMAB's 0.61 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. REGN currently trades 95.2% from its 52-week high vs GMAB's 83.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | GMABGenmab A/S | REGNRegeneron Pharmac… |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.61x | 0.58x |
| 52-Week HighHighest price in past year | $35.43 | $821.11 |
| 52-Week LowLowest price in past year | $17.24 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +83.1% | +95.2% |
| RSI (14)Momentum oscillator 0–100 | 38.3 | 49.1 |
| Avg Volume (50D)Average daily shares traded | 1.5M | 687K |
Analyst Outlook
Wall Street rates GMAB as "Buy" and REGN as "Buy". Consensus price targets imply 37.6% upside for GMAB (target: $41) vs 9.7% for REGN (target: $857). REGN is the only dividend payer here at 0.44% yield — a key consideration for income-focused portfolios.
| Metric | GMABGenmab A/S | REGNRegeneron Pharmac… |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $40.50 | $857.17 |
| # AnalystsCovering analysts | 17 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +0.4% |
| Dividend StreakConsecutive years of raises | — | 1 |
| Dividend / ShareAnnual DPS | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | +3.5% | +3.2% |
Historical Charts
Charts are rendered on first load. Hover for details.
Chart 1Total Return — 5 Years (Rebased to 100)
| Stock | Mar 20 | Feb 26 | Change |
|---|---|---|---|
| Genmab A/S (GMAB) | 100 | 138.39 | +38.4% |
| Regeneron Pharmaceu… (REGN) | 100 | 162.46 | +62.5% |
Regeneron Pharmaceu… (REGN) returned +70% over 5 years vs Genmab A/S (GMAB)'s -16%. A $10,000 investment in REGN 5 years ago would be worth $16,977 today (including dividends reinvested).
Chart 2Revenue Growth — 10 Years
| Stock | 2016 | 2025 | Change |
|---|---|---|---|
| Genmab A/S (GMAB) | $1.8B | $21.5B | +1085.3% |
| Regeneron Pharmaceu… (REGN) | $4.9B | $14.3B | +195.1% |
Regeneron Pharmaceuticals, Inc.'s revenue grew from $4.9B (2016) to $14.3B (2025) — a 12.8% CAGR.
Chart 3Net Margin Trend — 10 Years
| Stock | 2016 | 2025 | Change |
|---|---|---|---|
| Genmab A/S (GMAB) | 65.4% | 36.4% | -44.3% |
| Regeneron Pharmaceu… (REGN) | 18.4% | 31.4% | +70.5% |
Regeneron Pharmaceuticals, Inc.'s net margin went from 18% (2016) to 31% (2025).
Chart 4P/E Ratio History — 9 Years
| Stock | 2017 | 2025 | Change |
|---|---|---|---|
| Genmab A/S (GMAB) | 9.3 | 1.7 | -81.7% |
| Regeneron Pharmaceu… (REGN) | 36.4 | 18.6 | -48.9% |
Genmab A/S has traded in a 2x–9x P/E range over 8 years; current trailing P/E is ~15x. Regeneron Pharmaceuticals, Inc. has traded in a 9x–36x P/E range over 9 years; current trailing P/E is ~19x.
Chart 5EPS Growth — 10 Years
| Stock | 2016 | 2025 | Change |
|---|---|---|---|
| Genmab A/S (GMAB) | 1.92 | 12.14 | +532.3% |
| Regeneron Pharmaceu… (REGN) | 7.7 | 41.48 | +438.7% |
Regeneron Pharmaceuticals, Inc.'s EPS grew from $7.70 (2016) to $41.48 (2025) — a 21% CAGR.
Chart 6Free Cash Flow — 5 Years
Genmab A/S generated $8B FCF in 2024 (+284% vs 2021). Regeneron Pharmaceuticals, Inc. generated $4B FCF in 2025 (-38% vs 2021).
GMAB vs REGN: Frequently Asked Questions
9 questions · data-driven answers · updated daily
01Is GMAB or REGN a better buy right now?
Genmab A/S (GMAB) offers the better valuation at 15.4x trailing P/E (23.2x forward), making it the more compelling value choice. Analysts rate Genmab A/S (GMAB) a "Buy" — based on 17 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — GMAB or REGN?
On trailing P/E, Genmab A/S (GMAB) is the cheapest at 15.4x versus Regeneron Pharmaceuticals, Inc. at 18.8x. On forward P/E, Regeneron Pharmaceuticals, Inc. is actually cheaper at 17.3x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Genmab A/S wins at 0.80x versus Regeneron Pharmaceuticals, Inc.'s 2.73x — a PEG below 1.0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — GMAB or REGN?
Over the past 5 years, Regeneron Pharmaceuticals, Inc. (REGN) delivered a total return of +69.8%, compared to -16.2% for Genmab A/S (GMAB). A $10,000 investment in REGN five years ago would be worth approximately $17K today (assuming dividends reinvested). Over 10 years, the gap is even starker: GMAB returned +138.4% versus REGN's +104.7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — GMAB or REGN?
By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc. (REGN) is the lower-risk stock at 0.58β versus Genmab A/S's 0.61β — meaning GMAB is approximately 6% more volatile than REGN relative to the S&P 500. On balance sheet safety, Genmab A/S (GMAB) carries a lower debt/equity ratio of 3% versus 9% for Regeneron Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
05Which has better profit margins — GMAB or REGN?
Genmab A/S (GMAB) is the more profitable company, earning 36.4% net margin versus 31.4% for Regeneron Pharmaceuticals, Inc. — meaning it keeps 36.4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: GMAB leads at 31.1% versus 25.7% for REGN. At the gross margin level — before operating expenses — GMAB leads at 95.4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is GMAB or REGN more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential. By this metric, Genmab A/S (GMAB) is the more undervalued stock at a PEG of 0.80x versus Regeneron Pharmaceuticals, Inc.'s 2.73x. A PEG below 1.0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Regeneron Pharmaceuticals, Inc. (REGN) trades at 17.3x forward P/E versus 23.2x for Genmab A/S — 5.9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for GMAB: 37.6% to $40.50.
07Which pays a better dividend — GMAB or REGN?
In this comparison, REGN (0.4% yield) pays a dividend. GMAB does not pay a meaningful dividend and should not be held primarily for income.
08Is GMAB or REGN better for a retirement portfolio?
For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc. (REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.58), +104.7% 10Y return). Both have compounded well over 10 years (REGN: +104.7%, GMAB: +138.4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between GMAB and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. In terms of investment character: GMAB is a mid-cap deep-value stock; REGN is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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