Comprehensive Stock Comparison

Compare Aspire Biopharma Holdings, Inc. (ASBPW) vs Adaptive Biotechnologies Corporation (ADPT) Stock

Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.

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Quick Verdict

CategoryWinnerWhy
Quality / MarginsADPT logoADPT-31.5% net margin vs ASBPW's -16K%
Stability / SafetyASBPW logoASBPWBeta 0.76 vs ADPT's 1.31
DividendsTieNeither pays a meaningful dividend
Momentum (1Y)ADPT logoADPT+104.7% vs ASBPW's -63.8%
Efficiency (ROA)ADPT logoADPT-16.2% ROA vs ASBPW's -13.2%
Bottom line: ADPT leads in 3 of 5 categories, making it the stronger pick for investors who prioritize profitability and margin quality and recent price momentum and sentiment. Aspire Biopharma Holdings, Inc. is the better choice for capital preservation and lower volatility. As direct sector peers, they can serve as alternatives in the same portfolio allocation.

Who Each Stock Is For

Income & stability

Growth exposure

Long-term compounding (10Y)

Sleep-well-at-night portfolio

Defensive / Recession hedge

Business Model

What each company does and how it makes money

ASBPWAspire Biopharma Holdings, Inc.
Healthcare

Aspire Biopharma Holdings is a biotechnology company that develops advanced diagnostic solutions and molecular tests for disease detection. It generates revenue primarily through sales of its diagnostic assays and testing services to healthcare providers and research institutions. The company's competitive advantage lies in its proprietary genetic testing technology and specialized expertise in precision diagnostics.

ADPTAdaptive Biotechnologies Corporation
Healthcare

Adaptive Biotechnologies is a biotechnology company that develops immune medicine platforms for diagnosing and treating diseases like cancer, autoimmune disorders, and infectious diseases. It generates revenue primarily through its clinical diagnostics segment — including its clonoSEQ test for minimal residual disease monitoring — and its translational and clinical genomics research services, with diagnostics contributing roughly 60% of revenue. The company's key advantage lies in its proprietary immune medicine platform that maps and translates the genetics of the adaptive immune system into clinical diagnostics and therapies.

Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ASBPWAspire Biopharma Holdings, Inc.

Segment breakdown not available.

ADPTAdaptive Biotechnologies Corporation
FY 2021
Sequencing Revenue
51.1%$79M
Development Support Revenue
42.4%$65M
Development Revenue Regulatory Milestones
6.5%$10M

Financial Metrics Comparison

Side-by-side fundamentals across 2 stocks. BestLagging

Financial Scorecard

ADPT logoADPT 4ASBPW logoASBPW 0
Financial MetricsADPT logoADPT5/5 metrics
Valuation MetricsADPT logoADPT1/1 metrics
Profitability & EfficiencyADPT logoADPT3/5 metrics
Total ReturnsADPT logoADPT5/6 metrics
Risk & VolatilityTie1/2 metrics
Analyst Outlook0/0 metrics

ADPT leads in 4 of 6 categories — strongest in Financial Metrics and Valuation Metrics. 1 category is tied.

Financial Metrics (TTM)

ADPT is the larger business by revenue, generating $253M annually — 130218.4x ASBPW's $1,941. ADPT is the more profitable business, keeping -31.5% of every revenue dollar as net income compared to ASBPW's -16351.8%.

MetricASBPW logoASBPWAspire Biopharma …ADPT logoADPTAdaptive Biotechn…
RevenueTrailing 12 months$1,941$253M
EBITDAEarnings before interest/tax-$28M-$62M
Net IncomeAfter-tax profit-$32M-$80M
Free Cash FlowCash after capex-$4M-$63M
Gross MarginGross profit ÷ Revenue+45.5%+71.8%
Operating MarginEBIT ÷ Revenue-10314.0%-30.9%
Net MarginNet income ÷ Revenue-16351.8%-31.5%
FCF MarginFCF ÷ Revenue-1811.5%-24.9%
Rev. Growth (YoY)Latest quarter vs prior year+102.4%
EPS Growth (YoY)Latest quarter vs prior year+46.0%+126.6%
ADPT leads this category, winning 5 of 5 comparable metrics.

Valuation Metrics

MetricASBPW logoASBPWAspire Biopharma …ADPT logoADPTAdaptive Biotechn…
Market CapShares × price$178,899$2.5B
Enterprise ValueMkt cap + debt − cash$1M$2.5B
Trailing P/EPrice ÷ TTM EPS-0.01x-15.22x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue14.02x
Price / BookPrice ÷ Book value/share11.94x
Price / FCFMarket cap ÷ FCF
ADPT leads this category, winning 1 of 1 comparable metric.

Profitability & Efficiency

On the Piotroski fundamental quality scale (0–9), ADPT scores 4/9 vs ASBPW's 3/9, reflecting mixed financial health.

MetricASBPW logoASBPWAspire Biopharma …ADPT logoADPTAdaptive Biotechn…
ROE (TTM)Return on equity-39.0%
ROA (TTM)Return on assets-13.2%-16.2%
ROICReturn on invested capital-41.6%
ROCEReturn on capital employed-32.0%
Piotroski ScoreFundamental quality 0–934
Debt / EquityFinancial leverage0.44x
Net DebtTotal debt minus cash$1M$41M
Cash & Equiv.Liquid assets$3,633$48M
Total DebtShort + long-term debt$1M$89M
Interest CoverageEBIT ÷ Interest expense-10.51x-6.25x
ADPT leads this category, winning 3 of 5 comparable metrics.

Total Returns (with DRIP)

A $10,000 investment in ADPT five years ago would be worth $3,893 today (with dividends reinvested), compared to $2,583 for ASBPW. Over the past 12 months, ADPT leads with a +104.7% total return vs ASBPW's -63.8%. The 3-year compound annual growth rate (CAGR) favors ADPT at 24.8% vs ASBPW's -36.3% — a key indicator of consistent wealth creation.

MetricASBPW logoASBPWAspire Biopharma …ADPT logoADPTAdaptive Biotechn…
YTD ReturnYear-to-date+16.7%+3.3%
1-Year ReturnPast 12 months-63.8%+104.7%
3-Year ReturnCumulative with dividends-74.2%+94.3%
5-Year ReturnCumulative with dividends-74.2%-61.1%
10-Year ReturnCumulative with dividends-74.2%-59.2%
CAGR (3Y)Annualised 3-year return-36.3%+24.8%
ADPT leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

ASBPW is the less volatile stock with a 0.76 beta — it tends to amplify market swings less than ADPT's 1.31 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ADPT currently trades 79.2% from its 52-week high vs ASBPW's 24.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricASBPW logoASBPWAspire Biopharma …ADPT logoADPTAdaptive Biotechn…
Beta (5Y)Sensitivity to S&P 5000.76x1.31x
52-Week HighHighest price in past year$0.09$20.76
52-Week LowLowest price in past year$0.01$6.26
% of 52W HighCurrent price vs 52-week peak+24.1%+79.2%
RSI (14)Momentum oscillator 0–10049.046.2
Avg Volume (50D)Average daily shares traded41K1.8M
Evenly matched — ASBPW and ADPT each lead in 1 of 2 comparable metrics.

Analyst Outlook

MetricASBPW logoASBPWAspire Biopharma …ADPT logoADPTAdaptive Biotechn…
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$21.25
# AnalystsCovering analysts17
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.

Historical Charts

Charts are rendered on first load. Hover for details.

Chart 1Total Return — 5 Years (Rebased to 100)

StockFeb 25Mar 26Change
Aspire Biopharma Ho… (ASBPW)10028.81-71.2%
Adaptive Biotechnol… (ADPT)100199.01+99.0%

Adaptive Biotechnol… (ADPT) returned -61% over 5 years vs Aspire Biopharma Ho… (ASBPW)'s -74%.

Chart 2Revenue Growth — 10 Years

Stock20172024Change
Aspire Biopharma Ho… (ASBPW)$0.00$0.00
Adaptive Biotechnol… (ADPT)$38M$179M+365.5%

Adaptive Biotechnologies Corporation's revenue grew from $38M (2017) to $179M (2024) — a 24.6% CAGR.

Chart 3EPS Growth — 10 Years

Stock20172024Change
Aspire Biopharma Ho… (ASBPW)-0.07-1.52-1999.4%
Adaptive Biotechnol… (ADPT)-0.41-1.08-163.4%

Adaptive Biotechnologies Corporation's EPS grew from $-0.41 (2017) to $-1.08 (2024).

Chart 4Free Cash Flow — 5 Years

2021
$-254M
2022
$-5M
$-200M
2023
$-1M
$-167M
2024
$-0M
$-99M
Aspire Biopharma Ho… (ASBPW)Adaptive Biotechnol… (ADPT)

Aspire Biopharma Holdings, Inc. generated $-0M FCF in 2024 (+95% vs 2022). Adaptive Biotechnologies Corporation generated $-99M FCF in 2024 (+61% vs 2021).

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ASBPW vs ADPT: Frequently Asked Questions

7 questions · data-driven answers · updated daily

01

Is ASBPW or ADPT a better buy right now?

Analysts rate Adaptive Biotechnologies Corporation (ADPT) a "Buy" — based on 17 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ASBPW or ADPT?

Over the past 5 years, Adaptive Biotechnologies Corporation (ADPT) delivered a total return of -61.1%, compared to -74.2% for Aspire Biopharma Holdings, Inc. (ASBPW). A $10,000 investment in ADPT five years ago would be worth approximately $4K today (assuming dividends reinvested). Over 10 years, the gap is even starker: ADPT returned -59.2% versus ASBPW's -74.2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ASBPW or ADPT?

By beta (market sensitivity over 5 years), Aspire Biopharma Holdings, Inc. (ASBPW) is the lower-risk stock at 0.76β versus Adaptive Biotechnologies Corporation's 1.31β — meaning ADPT is approximately 73% more volatile than ASBPW relative to the S&P 500.

04

Which has better profit margins — ASBPW or ADPT?

Adaptive Biotechnologies Corporation (ADPT) is the more profitable company, earning -89.1% net margin versus -16351.8% for Aspire Biopharma Holdings, Inc. — meaning it keeps -89.1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADPT leads at -90.8% versus -10314.0% for ASBPW. At the gross margin level — before operating expenses — ADPT leads at 59.7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

05

Which pays a better dividend — ASBPW or ADPT?

None of the stocks in this comparison currently pay a material dividend. All are effectively zero-yield and should be held for capital appreciation rather than income.

06

Is ASBPW or ADPT better for a retirement portfolio?

For long-horizon retirement investors, Aspire Biopharma Holdings, Inc. (ASBPW) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.76)). Both have compounded well over 10 years (ASBPW: -74.2%, ADPT: -59.2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

07

What are the main differences between ASBPW and ADPT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Sector: Healthcare
  • Market Cap > $20B
  • Gross Margin > 27%
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 51%
  • Gross Margin > 43%
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