Comprehensive Stock Comparison
Compare BridgeBio Oncology Therapeutics Inc. (BBOT) vs ImmunityBio, Inc. (IBRX) Stock
Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.
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Quick Verdict
| Category | Winner | Why |
|---|---|---|
| Stability / Safety | BBOT | Beta 0.26 vs IBRX's 1.39 |
| Dividends | Tie | Neither pays a meaningful dividend |
| Momentum (1Y) | IBRX | +197.3% vs BBOT's -9.2% |
| Efficiency (ROA) | BBOT | -23.7% ROA vs IBRX's -93.2% |
Who Each Stock Is For
Income & stability
Growth exposure
Long-term compounding (10Y)
Sleep-well-at-night portfolio
Defensive / Recession hedge
Business Model
What each company does and how it makes money
BridgeBio Oncology Therapeutics is a clinical-stage biopharmaceutical company developing precision cancer drugs targeting specific genetic mutations in tumors. It generates revenue primarily through research collaborations and licensing deals — with future income dependent on successful drug development and commercialization — though currently in pre-revenue stage as it advances its clinical pipeline. The company's competitive advantage lies in its specialized focus on difficult-to-target oncogenes like KRAS and PI3Kα, leveraging BridgeBio Pharma's broader platform for drug discovery and development.
ImmunityBio is a clinical-stage biotechnology company developing immunotherapies and vaccines for cancers and infectious diseases. It generates revenue primarily through research collaborations and licensing agreements — though as a pre-commercial biotech, it currently relies heavily on equity financing and grants to fund its clinical trials. The company's competitive advantage lies in its integrated immunotherapy platform that combines multiple immune system activation approaches — including antibody cytokine fusion proteins, natural killer cells, and T-cell therapies — which could potentially create synergistic treatment effects.
Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Financial Metrics Comparison
Side-by-side fundamentals across 2 stocks. BestLagging
Financial Scorecard
IBRX leads in 3 of 6 categories (Financial Metrics, Valuation Metrics). BBOT leads in 1 (Profitability & Efficiency). 1 tied.
Financial Metrics (TTM)
IBRX and BBOT operate at a comparable scale, with $83M and $0 in trailing revenue.
| Metric | BBOTBridgeBio Oncolog… | IBRXImmunityBio, Inc. |
|---|---|---|
| RevenueTrailing 12 months | $0 | $83M |
| EBITDAEarnings before interest/tax | -$124M | -$245M |
| Net IncomeAfter-tax profit | -$115M | -$349M |
| Free Cash FlowCash after capex | -$96M | -$324M |
| Gross MarginGross profit ÷ Revenue | — | +94.8% |
| Operating MarginEBIT ÷ Revenue | — | -3.2% |
| Net MarginNet income ÷ Revenue | — | -4.2% |
| FCF MarginFCF ÷ Revenue | — | -3.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +4.3% |
| EPS Growth (YoY)Latest quarter vs prior year | -20.0% | +40.8% |
Valuation Metrics
| Metric | BBOTBridgeBio Oncolog… | IBRXImmunityBio, Inc. |
|---|---|---|
| Market CapShares × price | $794M | $9.6B |
| Enterprise ValueMkt cap + debt − cash | $793M | $10.0B |
| Trailing P/EPrice ÷ TTM EPS | 21.80x | -15.77x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 653.30x |
| Price / BookPrice ÷ Book value/share | 0.88x | — |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
| Metric | BBOTBridgeBio Oncolog… | IBRXImmunityBio, Inc. |
|---|---|---|
| ROE (TTM)Return on equity | -25.7% | — |
| ROA (TTM)Return on assets | -23.7% | -93.2% |
| ROICReturn on invested capital | -64.9% | — |
| ROCEReturn on capital employed | -83.3% | -88.9% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 |
| Debt / EquityFinancial leverage | — | — |
| Net DebtTotal debt minus cash | -$2M | $361M |
| Cash & Equiv.Liquid assets | $2M | $143M |
| Total DebtShort + long-term debt | $0 | $504M |
| Interest CoverageEBIT ÷ Interest expense | — | -2.48x |
Total Returns (with DRIP)
A $10,000 investment in BBOT five years ago would be worth $9,843 today (with dividends reinvested), compared to $2,937 for IBRX. Over the past 12 months, IBRX leads with a +197.3% total return vs BBOT's -9.2%. The 3-year compound annual growth rate (CAGR) favors IBRX at 58.8% vs BBOT's -0.5% — a key indicator of consistent wealth creation.
| Metric | BBOTBridgeBio Oncolog… | IBRXImmunityBio, Inc. |
|---|---|---|
| YTD ReturnYear-to-date | -18.4% | +384.2% |
| 1-Year ReturnPast 12 months | -9.2% | +197.3% |
| 3-Year ReturnCumulative with dividends | -1.6% | +300.8% |
| 5-Year ReturnCumulative with dividends | -1.6% | -70.6% |
| 10-Year ReturnCumulative with dividends | -1.6% | +42.2% |
| CAGR (3Y)Annualised 3-year return | -0.5% | +58.8% |
Risk & Volatility
BBOT is the less volatile stock with a 0.26 beta — it tends to amplify market swings less than IBRX's 1.39 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IBRX currently trades 78.7% from its 52-week high vs BBOT's 67.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | BBOTBridgeBio Oncolog… | IBRXImmunityBio, Inc. |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.26x | 1.39x |
| 52-Week HighHighest price in past year | $14.87 | $12.43 |
| 52-Week LowLowest price in past year | $8.50 | $1.83 |
| % of 52W HighCurrent price vs 52-week peak | +67.5% | +78.7% |
| RSI (14)Momentum oscillator 0–100 | 40.7 | 65.0 |
| Avg Volume (50D)Average daily shares traded | 267K | 32.7M |
Analyst Outlook
Wall Street rates BBOT as "Buy" and IBRX as "Buy". Consensus price targets imply 132.6% upside for BBOT (target: $23) vs 12.5% for IBRX (target: $11).
| Metric | BBOTBridgeBio Oncolog… | IBRXImmunityBio, Inc. |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $23.33 | $11.00 |
| # AnalystsCovering analysts | 2 | 5 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Historical Charts
Charts are rendered on first load. Hover for details.
Chart 1Total Return — 5 Years (Rebased to 100)
| Stock | Feb 24 | Feb 26 | Change |
|---|---|---|---|
| BridgeBio Oncology … (BBOT) | 100 | 118.06 | +18.1% |
| ImmunityBio, Inc. (IBRX) | 100 | 130.15 | +30.1% |
BridgeBio Oncology … (BBOT) returned -2% over 5 years vs ImmunityBio, Inc. (IBRX)'s -71%.
Chart 2Revenue Growth — 10 Years
| Stock | 2015 | 2024 | Change |
|---|---|---|---|
| BridgeBio Oncology … (BBOT) | $0.00 | $0.00 | — |
| ImmunityBio, Inc. (IBRX) | $236000.00 | $15M | +6147.9% |
ImmunityBio, Inc.'s revenue grew from $0M (2015) to $15M (2024) — a 58.3% CAGR.
Chart 3EPS Growth — 10 Years
| Stock | 2015 | 2024 | Change |
|---|---|---|---|
| BridgeBio Oncology … (BBOT) | -0 | 0.46 | +22004.8% |
| ImmunityBio, Inc. (IBRX) | -0.73 | -0.62 | +15.1% |
ImmunityBio, Inc.'s EPS grew from $-0.73 (2015) to $-0.62 (2024).
Chart 4Free Cash Flow — 5 Years
BridgeBio Oncology Therapeutics Inc. generated $-1M FCF in 2024. ImmunityBio, Inc. generated $-398M FCF in 2024 (-29% vs 2021).
BBOT vs IBRX: Frequently Asked Questions
7 questions · data-driven answers · updated daily
01Is BBOT or IBRX a better buy right now?
BridgeBio Oncology Therapeutics Inc. (BBOT) offers the better valuation at 21.8x trailing P/E, making it the more compelling value choice. Analysts rate BridgeBio Oncology Therapeutics Inc. (BBOT) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — BBOT or IBRX?
Over the past 5 years, BridgeBio Oncology Therapeutics Inc. (BBOT) delivered a total return of -1.6%, compared to -70.6% for ImmunityBio, Inc. (IBRX). A $10,000 investment in BBOT five years ago would be worth approximately $10K today (assuming dividends reinvested). Over 10 years, the gap is even starker: IBRX returned +42.2% versus BBOT's -1.6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — BBOT or IBRX?
By beta (market sensitivity over 5 years), BridgeBio Oncology Therapeutics Inc. (BBOT) is the lower-risk stock at 0.26β versus ImmunityBio, Inc.'s 1.39β — meaning IBRX is approximately 445% more volatile than BBOT relative to the S&P 500.
04Which has better profit margins — BBOT or IBRX?
BridgeBio Oncology Therapeutics Inc. (BBOT) is the more profitable company, earning 0.0% net margin versus -28.0% for ImmunityBio, Inc. — meaning it keeps 0.0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BBOT leads at 0.0% versus -23.3% for IBRX. At the gross margin level — before operating expenses — IBRX leads at 100.0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
05Which pays a better dividend — BBOT or IBRX?
None of the stocks in this comparison currently pay a material dividend. All are effectively zero-yield and should be held for capital appreciation rather than income.
06Is BBOT or IBRX better for a retirement portfolio?
For long-horizon retirement investors, BridgeBio Oncology Therapeutics Inc. (BBOT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.26)). Both have compounded well over 10 years (BBOT: -1.6%, IBRX: +42.2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
07What are the main differences between BBOT and IBRX?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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