Comprehensive Stock Comparison
Compare Theravance Biopharma, Inc. (TBPH) vs ADMA Biologics, Inc. (ADMA) Stock
Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.
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Quick Verdict
| Category | Winner | Why |
|---|---|---|
| Growth | ADMA | 65.2% revenue growth vs TBPH's 12.1% |
| Value | ADMA | Lower P/E (16.3x vs 20.2x) |
| Quality / Margins | ADMA | 42.9% net margin vs TBPH's 36.5% |
| Stability / Safety | TBPH | Beta 0.50 vs ADMA's 1.10 |
| Dividends | Tie | Neither pays a meaningful dividend |
| Momentum (1Y) | TBPH | +95.2% vs ADMA's -5.0% |
| Efficiency (ROA) | ADMA | 36.8% ROA vs TBPH's 7.1%, ROIC 37.7% vs -17.2% |
Who Each Stock Is For
Income & stability
Growth exposure
Long-term compounding (10Y)
Sleep-well-at-night portfolio
Defensive / Recession hedge
Business Model
What each company does and how it makes money
Theravance Biopharma is a biopharmaceutical company that discovers, develops, and commercializes respiratory and inflammatory disease medicines. It generates revenue primarily from sales of YUPELRI for COPD treatment — its only marketed product — supplemented by milestone payments and royalties from partnered programs. The company's competitive advantage lies in its expertise in respiratory drug development and its portfolio of novel, targeted therapies for underserved medical conditions.
ADMA Biologics is a biopharmaceutical company that develops, manufactures, and markets specialty plasma-derived biologics for treating immune deficiencies and infectious diseases. It generates revenue primarily from sales of its intravenous immune globulin products — BIVIGAM and ASCENIV — along with its Hepatitis B treatment Nabi-HB, while also operating plasma collection facilities. The company's key advantage is its integrated business model that combines plasma collection, manufacturing, and commercialization, creating a vertically controlled supply chain for plasma-derived therapies.
Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Financial Metrics Comparison
Side-by-side fundamentals across 2 stocks. BestLagging
Financial Scorecard
TBPH leads in 2 of 6 categories (Financial Metrics, Risk & Volatility). ADMA leads in 2 (Profitability & Efficiency, Total Returns). 1 tied.
Financial Metrics (TTM)
ADMA is the larger business by revenue, generating $489M annually — 6.1x TBPH's $80M. ADMA is the more profitable business, keeping 42.9% of every revenue dollar as net income compared to TBPH's 36.5%. On growth, TBPH holds the edge at +18.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | TBPHTheravance Biopha… | ADMAADMA Biologics, I… |
|---|---|---|
| RevenueTrailing 12 months | $80M | $489M |
| EBITDAEarnings before interest/tax | -$31M | $175M |
| Net IncomeAfter-tax profit | $29M | $209M |
| Free Cash FlowCash after capex | $243M | $41M |
| Gross MarginGross profit ÷ Revenue | +62.6% | +54.7% |
| Operating MarginEBIT ÷ Revenue | -40.9% | +34.2% |
| Net MarginNet income ÷ Revenue | +36.5% | +42.9% |
| FCF MarginFCF ÷ Revenue | +3.0% | +8.3% |
| Rev. Growth (YoY)Latest quarter vs prior year | +18.5% | +12.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +126.9% | 0.0% |
Valuation Metrics
| Metric | TBPHTheravance Biopha… | ADMAADMA Biologics, I… |
|---|---|---|
| Market CapShares × price | $925M | $3.7B |
| Enterprise ValueMkt cap + debt − cash | $937M | $3.7B |
| Trailing P/EPrice ÷ TTM EPS | -15.87x | 19.22x |
| Forward P/EPrice ÷ next-FY EPS est. | 20.21x | 16.30x |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | 25.10x |
| Price / SalesMarket cap ÷ Revenue | 14.36x | 8.70x |
| Price / BookPrice ÷ Book value/share | 5.08x | 10.86x |
| Price / FCFMarket cap ÷ FCF | — | 33.71x |
Profitability & Efficiency
ADMA delivers a 48.6% return on equity — every $100 of shareholder capital generates $49 in annual profit, vs $13 for TBPH. ADMA carries lower financial leverage with a 0.24x debt-to-equity ratio, signaling a more conservative balance sheet compared to TBPH's 0.28x. On the Piotroski fundamental quality scale (0–9), ADMA scores 7/9 vs TBPH's 4/9, reflecting strong financial health.
| Metric | TBPHTheravance Biopha… | ADMAADMA Biologics, I… |
|---|---|---|
| ROE (TTM)Return on equity | +12.6% | +48.6% |
| ROA (TTM)Return on assets | +7.1% | +36.8% |
| ROICReturn on invested capital | -17.2% | +37.7% |
| ROCEReturn on capital employed | -13.8% | +39.0% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 7 |
| Debt / EquityFinancial leverage | 0.28x | 0.24x |
| Net DebtTotal debt minus cash | $12M | -$21M |
| Cash & Equiv.Liquid assets | $38M | $103M |
| Total DebtShort + long-term debt | $50M | $82M |
| Interest CoverageEBIT ÷ Interest expense | -11.01x | 19.63x |
Total Returns (with DRIP)
A $10,000 investment in ADMA five years ago would be worth $64,339 today (with dividends reinvested), compared to $10,441 for TBPH. Over the past 12 months, TBPH leads with a +95.2% total return vs ADMA's -5.0%. The 3-year compound annual growth rate (CAGR) favors ADMA at 63.7% vs TBPH's 19.1% — a key indicator of consistent wealth creation.
| Metric | TBPHTheravance Biopha… | ADMAADMA Biologics, I… |
|---|---|---|
| YTD ReturnYear-to-date | +0.6% | -12.9% |
| 1-Year ReturnPast 12 months | +95.2% | -5.0% |
| 3-Year ReturnCumulative with dividends | +69.0% | +338.6% |
| 5-Year ReturnCumulative with dividends | +4.4% | +543.4% |
| 10-Year ReturnCumulative with dividends | +16.1% | +227.8% |
| CAGR (3Y)Annualised 3-year return | +19.1% | +63.7% |
Risk & Volatility
TBPH is the less volatile stock with a 0.50 beta — it tends to amplify market swings less than ADMA's 1.10 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. TBPH currently trades 86.8% from its 52-week high vs ADMA's 60.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | TBPHTheravance Biopha… | ADMAADMA Biologics, I… |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.50x | 1.10x |
| 52-Week HighHighest price in past year | $21.03 | $25.67 |
| 52-Week LowLowest price in past year | $7.90 | $13.50 |
| % of 52W HighCurrent price vs 52-week peak | +86.8% | +60.7% |
| RSI (14)Momentum oscillator 0–100 | 37.5 | 35.7 |
| Avg Volume (50D)Average daily shares traded | 331K | 1.8M |
Analyst Outlook
Wall Street rates TBPH as "Buy" and ADMA as "Buy". Consensus price targets imply 83.6% upside for TBPH (target: $34) vs 2.8% for ADMA (target: $16).
| Metric | TBPHTheravance Biopha… | ADMAADMA Biologics, I… |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $33.50 | $16.00 |
| # AnalystsCovering analysts | 14 | 9 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | 1 |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +0.3% | 0.0% |
Historical Charts
Charts are rendered on first load. Hover for details.
Chart 1Total Return — 5 Years (Rebased to 100)
| Stock | Mar 20 | Feb 26 | Change |
|---|---|---|---|
| Theravance Biopharm… (TBPH) | 100 | 78.01 | -22.0% |
| ADMA Biologics, Inc. (ADMA) | 100 | 589.23 | +489.2% |
ADMA Biologics, Inc. (ADMA) returned +543% over 5 years vs Theravance Biopharm… (TBPH)'s +4%. A $10,000 investment in ADMA 5 years ago would be worth $64,339 today (including dividends reinvested).
Chart 2Revenue Growth — 10 Years
| Stock | 2015 | 2024 | Change |
|---|---|---|---|
| Theravance Biopharm… (TBPH) | $42M | $64M | +52.8% |
| ADMA Biologics, Inc. (ADMA) | $7M | $426M | +5841.4% |
Theravance Biopharma, Inc.'s revenue grew from $42M (2015) to $64M (2024) — a 4.8% CAGR. ADMA Biologics, Inc.'s revenue grew from $7M (2015) to $426M (2024) — a 57.4% CAGR.
Chart 3Net Margin Trend — 10 Years
| Stock | 2015 | 2024 | Change |
|---|---|---|---|
| Theravance Biopharm… (TBPH) | -4.3% | -87.6% | -1925.9% |
| ADMA Biologics, Inc. (ADMA) | -2.5% | 46.4% | +1951.4% |
Theravance Biopharma, Inc.'s net margin went from -4% (2015) to -88% (2024). ADMA Biologics, Inc.'s net margin went from -3% (2015) to 46% (2024).
Chart 4EPS Growth — 10 Years
| Stock | 2015 | 2024 | Change |
|---|---|---|---|
| Theravance Biopharm… (TBPH) | -5.34 | -1.15 | +78.5% |
| ADMA Biologics, Inc. (ADMA) | -1.73 | 0.81 | +146.8% |
Theravance Biopharma, Inc.'s EPS grew from $-5.34 (2015) to $-1.15 (2024). ADMA Biologics, Inc.'s EPS grew from $-1.73 (2015) to $0.81 (2024).
Chart 5Free Cash Flow — 5 Years
Theravance Biopharma, Inc. generated $-12M FCF in 2024 (+94% vs 2021). ADMA Biologics, Inc. generated $110M FCF in 2024 (+187% vs 2021).
TBPH vs ADMA: Frequently Asked Questions
9 questions · data-driven answers · updated daily
01Is TBPH or ADMA a better buy right now?
ADMA Biologics, Inc. (ADMA) offers the better valuation at 19.2x trailing P/E (16.3x forward), making it the more compelling value choice. Analysts rate Theravance Biopharma, Inc. (TBPH) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TBPH or ADMA?
On forward P/E, ADMA Biologics, Inc. is actually cheaper at 16.3x.
03Which is the better long-term investment — TBPH or ADMA?
Over the past 5 years, ADMA Biologics, Inc. (ADMA) delivered a total return of +543.4%, compared to +4.4% for Theravance Biopharma, Inc. (TBPH). A $10,000 investment in ADMA five years ago would be worth approximately $64K today (assuming dividends reinvested). Over 10 years, the gap is even starker: ADMA returned +227.8% versus TBPH's +16.1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TBPH or ADMA?
By beta (market sensitivity over 5 years), Theravance Biopharma, Inc. (TBPH) is the lower-risk stock at 0.50β versus ADMA Biologics, Inc.'s 1.10β — meaning ADMA is approximately 122% more volatile than TBPH relative to the S&P 500. On balance sheet safety, ADMA Biologics, Inc. (ADMA) carries a lower debt/equity ratio of 24% versus 28% for Theravance Biopharma, Inc. — giving it more financial flexibility in a downturn.
05Which has better profit margins — TBPH or ADMA?
ADMA Biologics, Inc. (ADMA) is the more profitable company, earning 46.4% net margin versus -87.6% for Theravance Biopharma, Inc. — meaning it keeps 46.4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADMA leads at 32.6% versus -72.9% for TBPH. At the gross margin level — before operating expenses — TBPH leads at 100.0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is TBPH or ADMA more undervalued right now?
On forward earnings alone, ADMA Biologics, Inc. (ADMA) trades at 16.3x forward P/E versus 20.2x for Theravance Biopharma, Inc. — 3.9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for TBPH: 83.6% to $33.50.
07Which pays a better dividend — TBPH or ADMA?
None of the stocks in this comparison currently pay a material dividend. All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is TBPH or ADMA better for a retirement portfolio?
For long-horizon retirement investors, Theravance Biopharma, Inc. (TBPH) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.50)). Both have compounded well over 10 years (TBPH: +16.1%, ADMA: +227.8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between TBPH and ADMA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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