| Name | Market Cap | Current Price | P/E Ratio | Revenue Growth 1Y | Net Margin | ROE | FCF Yield | Debt/Equity |
|---|---|---|---|---|---|---|---|---|
| AUPHAurinia Pharmaceuticals Inc. | 1.96B | 14.87 | 378.37 | 33.97% | 29.28% | 21.28% | 2.25% | 0.21 |
| ARGXargenx SE | 50.33B | 813.24 | 63.63 | 78.6% | 23.34% | 15.14% | 0.01 | |
| INVAInnoviva, Inc. | 1.48B | 19.76 | 54.89 | 15.54% | 32.78% | 12.61% | 12.75% | 0.65 |
| GLPGGalapagos N.V. | 2.24B | 34.03 | 30.38 | 14.99% | -151.94% | -15.16% | 0.00 | |
| PTGXProtagonist Therapeutics, Inc. | 5.3B | 84.75 | 20.04 | 6.24% | 21.94% | 7.11% | 3.45% | 0.02 |
| ALMSAlumis Inc. Common Stock | 2.84B | 24.17 | -2.33 | -11.08% | -63.71% | 0.12 | ||
| PHATPhathom Pharmaceuticals, Inc. | 1.17B | 14.98 | -2.83 | 80.01% | -186.53% | |||
| ORKAOruka Therapeutics, Inc. | 1.57B | 32.50 | -6.51 | -22.44% | 0.00 |
| Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Revenue Growth % | - | - | - | - | - | - | - | - |
| Cost of Goods Sold | 271K | 488K | 0 | 0 | 0 | 0 | 0 | 3.45M |
| COGS % of Revenue | - | - | - | - | - | - | - | - |
| Gross Profit | -271K | -488K | 0 | 0 | 0 | 0 | 0 | -3.45M |
| Gross Margin % | - | - | - | - | - | - | - | - |
| Gross Profit Growth % | - | -0.8% | 1% | - | - | - | - | - |
| Operating Expenses | 20.21M | 19.15M | 32.52M | 63.47M | 130.71M | 145.6M | 143.72M | 150.62M |
| OpEx % of Revenue | - | - | - | - | - | - | - | - |
| Selling, General & Admin | 2.35M | 3.62M | 7.99M | 14.2M | 30.65M | 30.95M | 28.02M | 34.63M |
| SG&A % of Revenue | - | - | - | - | - | - | - | - |
| Research & Development | 17.85M | 15.53M | 24.52M | 49.27M | 100.07M | 112.5M | 113.76M | 119.45M |
| R&D % of Revenue | - | - | - | - | - | - | - | - |
| Other Operating Expenses | 0 | 844K | 0 | 0 | 0 | 2.15M | 1.95M | -3.45M |
| Operating Income | -20.48M | -19.15M | -32.52M | -63.47M | -130.71M | -145.6M | -143.72M | -154.07M |
| Operating Margin % | - | - | - | - | - | - | - | - |
| Operating Income Growth % | - | 0.06% | -0.7% | -0.95% | -1.06% | -0.11% | 0.01% | -0.07% |
| EBITDA | -20.21M | -18.66M | -32.02M | -62.8M | -128.57M | -143.45M | -141.57M | -150.62M |
| EBITDA Margin % | - | - | - | - | - | - | - | - |
| EBITDA Growth % | - | 0.08% | -0.72% | -0.96% | -1.05% | -0.12% | 0.01% | -0.06% |
| D&A (Non-Cash Add-back) | 271K | 488K | 493K | 667K | 2.14M | 2.15M | 2.15M | 3.45M |
| EBIT | -20.48M | -19.15M | -32.52M | -63.47M | -130.71M | -145.6M | -143.72M | -138.2M |
| Net Interest Income | 0 | 0 | 0 | 0 | 0 | 3.65M | 9.49M | 0 |
| Interest Income | 370K | 0 | 0 | 0 | 0 | 3.65M | 9.49M | 0 |
| Interest Expense | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Income/Expense | 1.77M | 844K | -4.66M | 57K | 390K | 3.65M | 9.49M | 15.87M |
| Pretax Income | -18.71M | -18.3M | -37.18M | -63.41M | -130.32M | -141.95M | -134.24M | -138.2M |
| Pretax Margin % | - | - | - | - | - | - | - | - |
| Income Tax | 1K | 1K | 4K | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 1% | 1% | 1% | 1% | 1% | 1% | 1% | 1% |
| Net Income | -18.71M | -18.3M | -37.18M | -63.41M | -130.32M | -141.95M | -134.24M | -138.2M |
| Net Margin % | - | - | - | - | - | - | - | - |
| Net Income Growth % | - | 0.02% | -1.03% | -0.71% | -1.06% | -0.09% | 0.05% | -0.03% |
| Net Income (Continuing) | -18.71M | -18.3M | -37.18M | -63.41M | -130.32M | -141.95M | -134.24M | -138.2M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.49 | -1.60 | -0.97 | -3.70 | -3.34 | -2.60 | -1.77 | -1.01 |
| EPS Growth % | - | -2.27% | 0.39% | -2.81% | 0.1% | 0.22% | 0.32% | 0.43% |
| EPS (Basic) | -0.49 | -1.60 | -0.97 | -3.70 | -3.34 | -2.60 | -1.77 | -1.01 |
| Diluted Shares Outstanding | 38.22M | 11.45M | 38.22M | 16.96M | 38.32M | 54.67M | 75.67M | 137.4M |
| Basic Shares Outstanding | 38.22M | 11.45M | 38.22M | 16.96M | 38.32M | 54.67M | 75.67M | 137.4M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - |
| Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 4.89M | 45.71M | 45.41M | 354.01M | 247.69M | 248.1M | 263.86M | 316.46M |
| Cash & Short-Term Investments | 2.97M | 44.17M | 43.93M | 351.21M | 242.72M | 242.66M | 259.72M | 312.02M |
| Cash Only | 2.97M | 44.17M | 43.93M | 268.56M | 74.84M | 140.02M | 225.11M | 49.5M |
| Short-Term Investments | 0 | 0 | 0 | 82.64M | 167.87M | 102.64M | 34.61M | 262.52M |
| Accounts Receivable | 582K | 225K | 79K | 3K | 0 | 0 | 0 | 0 |
| Days Sales Outstanding | - | - | - | - | - | - | - | - |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - |
| Other Current Assets | 0 | 0 | 0 | 0 | 463K | 203K | 63K | 1.1M |
| Total Non-Current Assets | 2.93M | 2.44M | 4.49M | 1.94M | 39.35M | 37M | 33.81M | 33.61M |
| Property, Plant & Equipment | 2.82M | 2.35M | 2.14M | 1.94M | 38.18M | 35.97M | 32.78M | 29.34M |
| Fixed Asset Turnover | - | - | - | - | - | - | - | - |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 0 | 0 | 0 | 0 | 1.03M | 0 | 0 |
| Other Non-Current Assets | 112K | 98K | 2.35M | 0 | 1.17M | 0 | 1.03M | 4.27M |
| Total Assets | 7.82M | 48.15M | 49.9M | 355.95M | 287.04M | 285.1M | 297.67M | 350.07M |
| Asset Turnover | - | - | - | - | - | - | - | - |
| Asset Growth % | - | 5.16% | 0.04% | 6.13% | -0.19% | -0.01% | 0.04% | 0.18% |
| Total Current Liabilities | 2.92M | 3.33M | 4.93M | 10.62M | 21.74M | 22.36M | 17.93M | 30.51M |
| Accounts Payable | 1.52M | 1.27M | 2.37M | 3.73M | 11.15M | 7.42M | 5.49M | 10.43M |
| Days Payables Outstanding | 2.05K | 950.65 | - | - | - | - | - | 1.1K |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 971K | 342K | 366K | 2.93M | 2.06M | 180K | 5.65M | 5.97M |
| Current Ratio | 1.68x | 13.74x | 9.21x | 33.33x | 11.39x | 11.10x | 14.72x | 10.37x |
| Quick Ratio | 1.68x | 13.74x | 9.21x | 33.33x | 11.39x | 11.10x | 14.72x | 10.37x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 51.12M | 6.94M | 1.44M | 1.05M | 33.39M | 31.54M | 29.19M | 26.45M |
| Long-Term Debt | 0 | 107.22M | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 0 | 0 | 0 | 0 | 33.39M | 31.54M | 29.19M | 26.45M |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 51.12M | -100.28M | 1.44M | 1.05M | 0 | 0 | 0 | 0 |
| Total Liabilities | 54.03M | 10.27M | 6.37M | 11.67M | 55.13M | 53.9M | 47.12M | 56.97M |
| Total Debt | 48.97M | 107.22M | 0 | 0 | 34.59M | 32.86M | 31.36M | 28.97M |
| Net Debt | 46.01M | 63.05M | -43.93M | -268.56M | -40.25M | -107.16M | -193.75M | -20.53M |
| Debt / Equity | - | 2.83x | - | - | 0.15x | 0.14x | 0.13x | 0.10x |
| Debt / EBITDA | - | - | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - |
| Interest Coverage | - | - | - | - | - | - | - | - |
| Total Equity | -46.21M | 37.88M | 43.53M | 344.28M | 231.91M | 231.19M | 250.56M | 293.11M |
| Equity Growth % | - | 1.82% | 0.15% | 6.91% | -0.33% | -0% | 0.08% | 0.17% |
| Book Value per Share | -1.21 | 3.31 | 1.14 | 20.30 | 6.05 | 4.23 | 3.31 | 2.13 |
| Total Shareholders' Equity | -46.21M | 37.88M | 43.53M | 344.28M | 231.91M | 231.19M | 250.56M | 293.11M |
| Common Stock | 3K | 4K | 4K | 38K | 39K | 48K | 78K | 109K |
| Retained Earnings | -47.09M | -65.4M | -102.58M | -165.99M | -296.31M | -438.26M | -572.5M | -710.7M |
| Treasury Stock | -905K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -26K | -66K | -80K | -77K | -180K | -372K | -52K | 10K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -19.26M | -17.19M | -28.36M | -53.09M | -106.11M | -116.31M | -121.14M | -118.01M |
| Operating CF Margin % | - | - | - | - | - | - | - | - |
| Operating CF Growth % | - | 0.11% | -0.65% | -0.87% | -1% | -0.1% | -0.04% | 0.03% |
| Net Income | -18.71M | -18.3M | -37.18M | -63.41M | -130.32M | -141.95M | -134.24M | -138.2M |
| Depreciation & Amortization | 271K | 488K | 493K | 667K | 3.41M | 2.11M | 2.15M | 2.15M |
| Stock-Based Compensation | 401K | 408K | 2.04M | 4.89M | 0 | 18.52M | 18.18M | 19.43M |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 799K | -260K | 5.67M | 53K | 17.52M | 1.28M | -1.43M | -7.75M |
| Working Capital Changes | -1.22M | 478K | 625K | 4.72M | 3.28M | 3.74M | -5.8M | 6.36M |
| Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 144K | -253K | 931K | 1.51M | 3.86M | -287K | -2.08M | 4.94M |
| Cash from Investing | -567K | -17K | -267K | -83.16M | -88.24M | 58.44M | 70.7M | -218.8M |
| Capital Expenditures | -567K | -17K | -267K | -464K | -1.65M | -6.53M | -193K | -15K |
| CapEx % of Revenue | - | - | - | - | - | - | - | - |
| Acquisitions | - | - | - | - | - | - | - | - |
| Investments | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | -82.7K | 0 | 64.97K | 0 | 0 |
| Cash from Financing | 42K | 58.46M | 28.39M | 360.88M | 1.79M | 122.91M | 135.52M | 161.21M |
| Debt Issued (Net) | - | - | - | - | - | - | - | - |
| Equity Issued (Net) | - | - | - | - | - | - | - | - |
| Dividends Paid | 0 | 0 | 0 | -6.22M | 0 | 0 | 0 | 0 |
| Share Repurchases | - | - | - | - | - | - | - | - |
| Other Financing | 42K | 121K | -1.6M | 3.27M | 0 | -7.57M | 14K | -665K |
| Net Change in Cash | - | - | - | - | - | - | - | - |
| Free Cash Flow | -19.83M | -17.21M | -28.63M | -53.55M | -107.76M | -122.83M | -121.33M | -118.02M |
| FCF Margin % | - | - | - | - | - | - | - | - |
| FCF Growth % | - | 0.13% | -0.66% | -0.87% | -1.01% | -0.14% | 0.01% | 0.03% |
| FCF per Share | -0.52 | -1.50 | -0.75 | -3.16 | -2.81 | -2.25 | -1.60 | -0.86 |
| FCF Conversion (FCF/Net Income) | 1.03x | 0.94x | 0.76x | 0.84x | 0.81x | 0.82x | 0.90x | 0.85x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 1K | 2K | 0 | 0 | 0 | 0 | 4.89M |
| Metric | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 |
|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | - | -48.32% | -91.35% | -32.7% | -45.24% | -61.3% | -55.73% | -50.84% |
| Return on Invested Capital (ROIC) | - | -28.51% | -48.52% | -126.41% | -73.33% | -69.18% | -119.22% | -70.17% |
| Debt / Equity | - | 2.83x | - | - | 0.15x | 0.14x | 0.13x | 0.10x |
| FCF Conversion | 1.03x | 0.94x | 0.76x | 0.84x | 0.81x | 0.82x | 0.90x | 0.85x |
Annexon, Inc. (ANNX) grew revenue by 0.0% over the past year. Growth has been modest.
Annexon, Inc. (ANNX) reported a net loss of $207.0M for fiscal year 2024.
Annexon, Inc. (ANNX) has a return on equity (ROE) of -50.8%. Negative ROE indicates the company is unprofitable.
Annexon, Inc. (ANNX) had negative free cash flow of $176.6M in fiscal year 2024, likely due to heavy capital investments.