8-K Announcements
6Mar 30, 2026·SEC
Feb 17, 2026·SEC
Jan 14, 2026·SEC
Annexon, Inc. (ANNX) fundamental analysis — strengths, weaknesses & financial health based on data analysis
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
Annexon, Inc. (ANNX) stock price & volume — 10-year historical chart
Annexon, Inc. (ANNX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Annexon, Inc. (ANNX) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | Mar 30, 2026 | $0.28vs $0.32+12.5% | —vs $3M |
| Q4 2025 | Nov 10, 2025 | $0.37vs $0.34-8.8% | — |
| Q3 2025 | Aug 14, 2025 | $0.34vs $0.36+5.6% | — |
| Q2 2025 | May 12, 2025 | $0.37vs $0.30-23.3% | — |
Annexon, Inc. (ANNX) competitors in Immunology and Inflammation Therapies — business model, growth, and fundamentals comparison
Annexon, Inc. (ANNX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Annexon, Inc. (ANNX) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | TTM |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Revenue Growth % | - | - | - | - | - | - | - | - | - |
| Cost of Goods Sold | 271K | 488K | 0 | 0 | 0 | 0 | 0 | 3.45M | 0 |
| COGS % of Revenue | - | - | - | - | - | - | - | - | - |
| Gross Profit | -271K▲ 0% | -488K▼ 80.1% | 0▲ 100.0% | 0▲ 0% | 0▲ 0% | 0▲ 0% | 0▲ 0% | -3.45M▲ 0% | 0▲ 0% |
| Gross Margin % | - | - | - | - | - | - | - | - | - |
| Gross Profit Growth % | - | -80.07% | 100% | - | - | - | - | - | - |
| Operating Expenses | 20.21M | 19.15M | 32.52M | 63.47M | 130.71M | 145.6M | 143.72M | 150.62M | 218.63M |
| OpEx % of Revenue | - | - | - | - | - | - | - | - | - |
| Selling, General & Admin | 2.35M | 3.62M | 7.99M | 14.2M | 30.65M | 30.95M | 28.02M | 34.63M | 30.02M |
| SG&A % of Revenue | - | - | - | - | - | - | - | - | - |
| Research & Development | 17.85M | 15.53M | 24.52M | 49.27M | 100.07M | 112.5M | 113.76M | 119.45M | 185.39M |
| R&D % of Revenue | - | - | - | - | - | - | - | - | - |
| Other Operating Expenses | 0 | 844K | 0 | 0 | 0 | 2.15M | 1.95M | -3.45M | 1.61M |
| Operating Income | -20.48M▲ 0% | -19.15M▲ 6.5% | -32.52M▼ 69.8% | -63.47M▼ 95.2% | -130.71M▼ 105.9% | -145.6M▼ 11.4% | -143.72M▲ 1.3% | -154.07M▼ 7.2% | -218.63M▲ 0% |
| Operating Margin % | - | - | - | - | - | - | - | - | - |
| Operating Income Growth % | - | 6.5% | -69.83% | -95.18% | -105.95% | -11.39% | 1.29% | -7.2% | - |
| EBITDA | -20.21M | -18.66M | -32.02M | -62.8M | -128.57M | -143.45M | -141.57M | -150.62M | -216.39M |
| EBITDA Margin % | - | - | - | - | - | - | - | - | - |
| EBITDA Growth % | - | 7.66% | -71.63% | -96.1% | -104.73% | -11.57% | 1.31% | -6.39% | -67.29% |
| D&A (Non-Cash Add-back) | 271K | 488K | 493K | 667K | 2.14M | 2.15M | 2.15M | 3.45M | 2.23M |
| EBIT | -20.48M | -19.15M | -32.52M | -63.47M | -130.71M | -145.6M | -143.72M | -138.2M | -216.53M |
| Net Interest Income | 0 | 0 | 0 | 0 | 0 | 3.65M | 9.49M | 0 | 11.6M |
| Interest Income | 370K | 0 | 0 | 0 | 0 | 3.65M | 9.49M | 0 | 11.6M |
| Interest Expense | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Income/Expense | 1.77M | 844K | -4.66M | 57K | 390K | 3.65M | 9.49M | 15.87M | 11.6M |
| Pretax Income | -18.71M▲ 0% | -18.3M▲ 2.2% | -37.18M▼ 103.1% | -63.41M▼ 70.6% | -130.32M▼ 105.5% | -141.95M▼ 8.9% | -134.24M▲ 5.4% | -138.2M▼ 3.0% | -207.02M▲ 0% |
| Pretax Margin % | - | - | - | - | - | - | - | - | - |
| Income Tax | 1K | 1K | 4K | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | -0.01% | -0.01% | -0.01% | 0% | 0% | 0% | 0% | 0% | 0% |
| Net Income | -18.71M▲ 0% | -18.3M▲ 2.2% | -37.18M▼ 103.1% | -63.41M▼ 70.5% | -130.32M▼ 105.5% | -141.95M▼ 8.9% | -134.24M▲ 5.4% | -138.2M▼ 3.0% | -207.02M▲ 0% |
| Net Margin % | - | - | - | - | - | - | - | - | - |
| Net Income Growth % | - | 2.16% | -103.14% | -70.54% | -105.52% | -8.92% | 5.43% | -2.95% | -76.19% |
| Net Income (Continuing) | -18.71M | -18.3M | -37.18M | -63.41M | -130.32M | -141.95M | -134.24M | -138.2M | -207.02M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.49▲ 0% | -1.60▼ 226.5% | -0.97▲ 39.4% | -3.70▼ 281.4% | -3.34▲ 9.7% | -2.60▲ 22.2% | -1.77▲ 31.9% | -1.01▲ 42.9% | -1.39▲ 0% |
| EPS Growth % | - | -226.53% | 39.38% | -281.44% | 9.73% | 22.16% | 31.92% | 42.94% | -34.29% |
| EPS (Basic) | -0.49 | -1.60 | -0.97 | -3.70 | -3.34 | -2.60 | -1.77 | -1.01 | - |
| Diluted Shares Outstanding | 38.22M | 11.45M | 38.22M | 16.96M | 38.32M | 54.67M | 75.67M | 137.4M | 149.12M |
| Basic Shares Outstanding | 38.22M | 11.45M | 38.22M | 16.96M | 38.32M | 54.67M | 75.67M | 137.4M | 149.12M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
Annexon, Inc. (ANNX) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | TTM |
|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 4.89M | 45.71M | 45.41M | 354.01M | 247.69M | 248.1M | 263.86M | 316.46M | 192.82M |
| Cash & Short-Term Investments | 2.97M | 44.17M | 43.93M | 351.21M | 242.72M | 242.66M | 259.72M | 312.02M | 188.72M |
| Cash Only | 2.97M | 44.17M | 43.93M | 268.56M | 74.84M | 140.02M | 225.11M | 49.5M | 139.42M |
| Short-Term Investments | 0 | 0 | 0 | 82.64M | 167.87M | 102.64M | 34.61M | 262.52M | 49.3M |
| Accounts Receivable | 582K | 225K | 79K | 3K | 0 | 0 | 0 | 0 | 0 |
| Days Sales Outstanding | - | - | - | - | - | - | - | - | - |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | - |
| Other Current Assets | 0 | 0 | 0 | 0 | 463K | 203K | 63K | 1.1M | 1.38M |
| Total Non-Current Assets | 2.93M | 2.44M | 4.49M | 1.94M | 39.35M | 37M | 33.81M | 33.61M | 36.32M |
| Property, Plant & Equipment | 2.82M | 2.35M | 2.14M | 1.94M | 38.18M | 35.97M | 32.78M | 29.34M | 26.74M |
| Fixed Asset Turnover | - | - | - | - | - | - | - | - | 0.00x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 0 | 0 | 0 | 0 | 1.03M | 0 | 0 | 0 |
| Other Non-Current Assets | 112K | 98K | 2.35M | 0 | 1.17M | 0 | 1.03M | 4.27M | 26.51M |
| Total Assets | 7.82M▲ 0% | 48.15M▲ 515.6% | 49.9M▲ 3.6% | 355.95M▲ 613.3% | 287.04M▼ 19.4% | 285.1M▼ 0.7% | 297.67M▲ 4.4% | 350.07M▲ 17.6% | 229.14M▲ 0% |
| Asset Turnover | - | - | - | - | - | - | - | - | 0.00x |
| Asset Growth % | - | 515.64% | 3.63% | 613.35% | -19.36% | -0.68% | 4.41% | 17.6% | -57.09% |
| Total Current Liabilities | 2.92M | 3.33M | 4.93M | 10.62M | 21.74M | 22.36M | 17.93M | 30.51M | 43.58M |
| Accounts Payable | 1.52M | 1.27M | 2.37M | 3.73M | 11.15M | 7.42M | 5.49M | 10.43M | 18.22M |
| Days Payables Outstanding | 2.05K | 950.65 | - | - | - | - | - | 1.1K | - |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 971K | 342K | 366K | 2.93M | 2.06M | 180K | 5.65M | 5.97M | 6.43M |
| Current Ratio | 1.68x | 13.74x | 9.21x | 33.33x | 11.39x | 11.10x | 14.72x | 10.37x | 10.37x |
| Quick Ratio | 1.68x | 13.74x | 9.21x | 33.33x | 11.39x | 11.10x | 14.72x | 10.37x | 10.37x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 51.12M | 6.94M | 1.44M | 1.05M | 33.39M | 31.54M | 29.19M | 26.45M | 24.12M |
| Long-Term Debt | 0 | 107.22M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 0 | 0 | 0 | 0 | 33.39M | 31.54M | 29.19M | 26.45M | 101.18M |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 51.12M | -100.28M | 1.44M | 1.05M | 0 | 0 | 0 | 0 | 0 |
| Total Liabilities | 54.03M | 10.27M | 6.37M | 11.67M | 55.13M | 53.9M | 47.12M | 56.97M | 67.7M |
| Total Debt | 48.97M | 107.22M | 0 | 0 | 34.59M | 32.86M | 31.36M | 28.97M | 26.94M |
| Net Debt | 46.01M | 63.05M | -43.93M | -268.56M | -40.25M | -107.16M | -193.75M | -20.53M | -112.48M |
| Debt / Equity | - | 2.83x | - | - | 0.15x | 0.14x | 0.13x | 0.10x | 0.10x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | -0.12x |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | 0.52x |
| Interest Coverage | - | - | - | - | - | - | - | - | - |
| Total Equity | -46.21M▲ 0% | 37.88M▲ 182.0% | 43.53M▲ 14.9% | 344.28M▲ 690.9% | 231.91M▼ 32.6% | 231.19M▼ 0.3% | 250.56M▲ 8.4% | 293.11M▲ 17.0% | 161.44M▲ 0% |
| Equity Growth % | - | 181.97% | 14.92% | 690.9% | -32.64% | -0.31% | 8.37% | 16.98% | -86.3% |
| Book Value per Share | -1.21 | 3.31 | 1.14 | 20.30 | 6.05 | 4.23 | 3.31 | 2.13 | 1.08 |
| Total Shareholders' Equity | -46.21M | 37.88M | 43.53M | 344.28M | 231.91M | 231.19M | 250.56M | 293.11M | 161.44M |
| Common Stock | 3K | 4K | 4K | 38K | 39K | 48K | 78K | 109K | 115K |
| Retained Earnings | -47.09M | -65.4M | -102.58M | -165.99M | -296.31M | -438.26M | -572.5M | -710.7M | -869.13M |
| Treasury Stock | -905K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -26K | -66K | -80K | -77K | -180K | -372K | -52K | 10K | -76K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Annexon, Inc. (ANNX) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | TTM |
|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -19.26M | -17.19M | -28.36M | -53.09M | -106.11M | -116.31M | -121.14M | -118.01M | -118.01M |
| Operating CF Margin % | - | - | - | - | - | - | - | - | - |
| Operating CF Growth % | - | 10.75% | -64.97% | -87.2% | -99.88% | -9.61% | -4.16% | 2.59% | -269.23% |
| Net Income | -18.71M | -18.3M | -37.18M | -63.41M | -130.32M | -141.95M | -134.24M | -138.2M | -207.02M |
| Depreciation & Amortization | 271K | 488K | 493K | 667K | 3.41M | 2.11M | 2.15M | 2.15M | 2.16M |
| Stock-Based Compensation | 401K | 408K | 2.04M | 4.89M | 0 | 18.52M | 18.18M | 19.43M | 18.34M |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 799K | -260K | 5.67M | 53K | 17.52M | 1.28M | -1.43M | -7.75M | -5.14M |
| Working Capital Changes | -1.22M | 478K | 625K | 4.72M | 3.28M | 3.74M | -5.8M | 6.36M | 15.22M |
| Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 144K | -253K | 931K | 1.51M | 3.86M | -287K | -2.08M | 4.94M | 11.45M |
| Cash from Investing | -567K | -17K | -267K | -83.16M | -88.24M | 58.44M | 70.7M | -218.8M | 217.59M |
| Capital Expenditures | -567K | -17K | -267K | -464K | -1.65M | -6.53M | -193K | -15K | -143K |
| CapEx % of Revenue | - | - | - | - | - | - | - | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | -64.97K | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | -82.7K | 0 | 64.97K | 0 | 0 | 0 |
| Cash from Financing | 42K | 58.46M | 28.39M | 360.88M | 1.79M | 122.91M | 135.52M | 161.21M | 18.74M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 0 | 58.34M | 30M | 363.83M | 1.79M | 130.48M | 135.51M | 161.87M | 19.04M |
| Dividends Paid | 0 | 0 | 0 | -6.22M | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 42K | 121K | -1.6M | 3.27M | 0 | -7.57M | 14K | -665K | -292K |
| Net Change in Cash | -19.81M▲ 0% | 41.21M▲ 308.0% | -244K▼ 100.6% | 224.63M▲ 92163.1% | -193.72M▼ 186.2% | 65.04M▲ 133.6% | 85.09M▲ 30.8% | -175.61M▼ 306.4% | 59.88M▲ 0% |
| Free Cash Flow | -19.83M▲ 0% | -17.21M▲ 13.2% | -28.63M▼ 66.4% | -53.55M▼ 87.1% | -107.76M▼ 101.2% | -122.83M▼ 14.0% | -121.33M▲ 1.2% | -118.02M▲ 2.7% | -176.59M▲ 0% |
| FCF Margin % | - | - | - | - | - | - | - | - | - |
| FCF Growth % | - | 13.21% | -66.36% | -87.08% | -101.24% | -13.99% | 1.22% | 2.73% | -67.41% |
| FCF per Share | -0.52 | -1.50 | -0.75 | -3.16 | -2.81 | -2.25 | -1.60 | -0.86 | -0.86 |
| FCF Conversion (FCF/Net Income) | 1.03x | 0.94x | 0.76x | 0.84x | 0.81x | 0.82x | 0.90x | 0.85x | 0.85x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 1K | 2K | 0 | 0 | 0 | 0 | 4.89M | 0 |
Annexon, Inc. (ANNX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | TTM |
|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -48.32% | -91.35% | -32.7% | -45.24% | -61.3% | -55.73% | -50.84% | -92.28% |
| Return on Invested Capital (ROIC) | -28.51% | -48.52% | -126.41% | -73.33% | -69.18% | -119.22% | -70.17% | -70.17% |
| Debt / Equity | 2.83x | - | - | 0.15x | 0.14x | 0.13x | 0.10x | 0.10x |
| FCF Conversion | 0.94x | 0.76x | 0.84x | 0.81x | 0.82x | 0.90x | 0.85x | 0.85x |
Annexon, Inc. (ANNX) SEC filings — annual & quarterly reports (10-K, 10-Q)
Mar 30, 2026·SEC
Feb 17, 2026·SEC
Jan 14, 2026·SEC
Annexon, Inc. (ANNX) stock FAQ — growth, dividends, profitability & financials explained
Annexon, Inc. (ANNX) grew revenue by 0.0% over the past year. Growth has been modest.
Annexon, Inc. (ANNX) reported a net loss of $207.0M for fiscal year 2024.
Annexon, Inc. (ANNX) has a return on equity (ROE) of -50.8%. Negative ROE indicates the company is unprofitable.
Annexon, Inc. (ANNX) had negative free cash flow of $176.6M in fiscal year 2024, likely due to heavy capital investments.
Annexon, Inc. (ANNX) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates