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TLSA logoTiziana Life Sciences Ltd(TLSA)Earnings, Financials & Key Ratios

TLSA•NASDAQ
$1.47
$187M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutTiziana Life Sciences Ltd, a biotechnology company, focuses on the discovery and development of molecules to treat human diseases in oncology and immunology. The company's lead product candidate in immunology is Foralumab (TZLS-401), a human anti-CD3 monoclonal antibody (mAb) for the treatment of Crohn's, graft versus host, ulcerative colitis, multiple sclerosis, type-1 diabetes, inflammatory bowel, psoriasis, and rheumatoid arthritis diseases. It also develops Milciclib (TZLS-201), a small molecule inhibitor of various cyclin-dependent kinases, tropomycin receptor kinases, and Src family kinases controlling cell growth and malignant progression of cancer; and anti-Interleukin 6 receptor (IL6R) mAb (TZLS-501), a fully human monoclonal antibody for the treatment of IL6-induced inflammation and to treat COVID-19 patients. The company was incorporated in 1998 and is headquatered in London, the United Kingdom.Show more
  • Revenue$0
  • EBITDA-$16M+12.4%
  • Net Income-$12M+32.9%
  • EPS (Diluted)-0.22+35.3%
  • ROE-250.49%-77.7%
  • ROIC-481.72%-14.5%
  • Debt/Equity0.03-39.6%
  • Interest Coverage-2632.33-46.4%
Technical→

TLSA Key Insights

Tiziana Life Sciences Ltd (TLSA) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Trading more than 30% below 52-week high
  • ✗Expensive at 19.9x book value
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

TLSA Price & Volume

Tiziana Life Sciences Ltd (TLSA) stock price & volume — 10-year historical chart

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TLSA Growth Metrics

Tiziana Life Sciences Ltd (TLSA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-56.61%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-70.78%

Return on Capital

10 Years-431.28%
5 Years-133.31%
3 Years-172.91%
Last Year-329.69%

TLSA Recent Earnings

Tiziana Life Sciences Ltd (TLSA) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 0/12 qtrs (0%)
Q3 2025Latest
Jul 8, 2025
EPS
$0.10
Est $0.07
-35.4%
Revenue
—
Q3 2025
Jun 23, 2025
EPS
$0.13
Revenue
—
Q2 2025
May 20, 2025
EPS
$0.06
Revenue
—
Q3 2024
Jun 30, 2024
EPS
$0.18
Revenue
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q3 2025LatestJul 8, 2025
$0.10vs $0.07-35.4%
—
Q3 2025Jun 23, 2025
$0.13
—
Q2 2025May 20, 2025
$0.06
—
Q3 2024Jun 30, 2024
$0.18
—
Based on last 12 quarters of dataView full earnings history →

TLSA Peer Comparison

Tiziana Life Sciences Ltd (TLSA) competitors in Immunology and Inflammation Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
IMVT logoIMVTImmunovant, Inc.Direct Competitor5.83B28.67-10.50-47.07%0.00
ARCT logoARCTArcturus Therapeutics Holdings Inc.Direct Competitor259.5M9.13-3.80-51.43%-88.75%-29.13%0.12
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor7.61B337.95-25.07-100%-58.74%0.00
KYMR logoKYMRKymera Therapeutics, Inc.Direct Competitor7.04B86.26-23.38-16.72%-6.12%-25.02%0.05
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.62B26.00-7.90-4.26%-156.36%-68.97%0.16
INVA logoINVAInnoviva, Inc.Product Competitor1.91B22.526.8218.52%118.91%46.47%0.23
AGIO logoAGIOAgios Pharmaceuticals, Inc.Product Competitor1.6B26.98-3.7948.03%-6.4%-34.11%0.05
FATE logoFATEFate Therapeutics, Inc.Product Competitor264.17M2.29-1.99-51.24%-20.51%-65.79%0.38

Compare TLSA vs Peers

Tiziana Life Sciences Ltd (TLSA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for TLSA.

Scale Benchmark

vs MEDP

Larger-name benchmark to compare TLSA against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, ARCT, PRAX, KYMR

TLSA Income Statement

Tiziana Life Sciences Ltd (TLSA) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24
Sales/Revenue000000000
Revenue Growth %---------
Cost of Goods Sold000000000
COGS % of Revenue---------
Gross Profit
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
Gross Margin %---------
Gross Profit Growth %---------
Operating Expenses7.29M8.25M7.82M7.77M28.03M27.37M14.59M17.98M15.79M
OpEx % of Revenue---------
Selling, General & Admin000013.21M855K000
SG&A % of Revenue---------
Research & Development2.96M4.67M4.34M2.91M5.99M13.21M12.96M8.11M5.23M
R&D % of Revenue---------
Other Operating Expenses4.33M3.57M3.48M4.86M8.82M13.31M1.63M9.87M10.56M
Operating Income
-7.29M▲ 0%
-8.25M▼ 13.1%
-7.82M▲ 5.1%
-7.77M▲ 0.7%
-28.03M▼ 260.6%
-27.37M▲ 2.3%
-14.59M▲ 46.7%
-17.98M▼ 23.3%
-15.79M▲ 12.2%
Operating Margin %---------
Operating Income Growth %15.39%-13.14%5.12%0.65%-260.56%2.33%46.72%-23.3%12.18%
EBITDA-7.28M-8.23M-7.81M-7.58M-27.94M-27.23M-14.54M-17.89M-15.67M
EBITDA Margin %---------
EBITDA Growth %15.49%-13.12%5.14%3.03%-268.8%2.52%46.63%-23.07%12.4%
D&A (Non-Cash Add-back)8K11K12.61K198K89.76K141K51K96K124K
EBIT-7.29M-8.25M-7.82M-7.77M-27.98M-26.48M-15.39M-17.23M-16.74M
Net Interest Income000-72K-312K-176K-7K1.14M808K
Interest Income0001K8K001.15M814K
Interest Expense9K9K9.46K73K320K176K7K10K6K
Other Income/Expense-9K-9K-8.67K-73K-312K717K-811K742K-952K
Pretax Income
-7.3M▲ 0%
-8.26M▼ 13.1%
-7.83M▲ 5.1%
-7.85M▼ 0.2%
-28.34M▼ 261.2%
-26.66M▲ 5.9%
-15.4M▲ 42.2%
-17.24M▼ 12.0%
-16.75M▲ 2.9%
Pretax Margin %---------
Income Tax-89K-1.49M-1.53M-540K-2.21M-3.24M0449K-4.88M
Effective Tax Rate %1.22%17.99%19.58%6.88%7.79%12.15%0%-2.6%29.16%
Net Income
-7.21M▲ 0%
-6.77M▲ 6.1%
-6.3M▲ 7.0%
-7.31M▼ 16.0%
-26.13M▼ 257.7%
-23.42M▲ 10.4%
-15.4M▲ 34.2%
-17.69M▼ 14.9%
-11.86M▲ 32.9%
Net Margin %---------
Net Income Growth %16.5%6.08%6.96%-15.98%-257.66%10.39%34.25%-14.9%32.94%
Net Income (Continuing)-7.21M-6.77M-6.3M-7.31M-26.13M-23.42M-15.4M-17.69M-11.86M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
-0.14▲ 0%
-0.12▲ 14.3%
-0.09▲ 23.0%
-0.11▼ 19.0%
-0.54▼ 390.9%
-0.48▲ 11.1%
-0.30▲ 37.5%
-0.34▼ 13.3%
-0.22▲ 35.3%
EPS Growth %22.22%14.29%23%-19.05%-390.91%11.11%37.5%-13.33%35.29%
EPS (Basic)-0.14-0.12-0.09-0.11-0.54-0.48-0.30-0.34-0.22
Diluted Shares Outstanding53.2M58.49M68.24M68.24M48.65M48.97M50.76M50.76M53.34M
Basic Shares Outstanding53.2M58.49M68.24M68.24M48.65M48.97M50.76M50.76M53.34M
Dividend Payout Ratio---------

TLSA Balance Sheet

Tiziana Life Sciences Ltd (TLSA) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24
Total Current Assets5.02M1.81M5.45M1.14M70.18M48.68M24.28M7.34M7.51M
Cash & Short-Term Investments4.7M48K4.18M153K65.82M42.19M18.12M1.18M3.72M
Cash Only4.7M48K4.18M153K65.82M42.19M18.12M1.18M3.72M
Short-Term Investments000000000
Accounts Receivable00003.78M5.27M5.86M6.05M3.69M
Days Sales Outstanding---------
Inventory0000-2.28K0000
Days Inventory Outstanding---------
Other Current Assets320K1.76M1.27M991K193K0000
Total Non-Current Assets28K18K5.52K664K480K147K2.19M4.85M3.78M
Property, Plant & Equipment28K18K5.52K334K359.51K17K389K293K187K
Fixed Asset Turnover---------
Goodwill0000-35.59K0000
Intangible Assets0000132.59K130K000
Long-Term Investments0000001.81M4.55M3.59M
Other Non-Current Assets000330K23.49K0000
Total Assets
5.05M▲ 0%
1.83M▼ 63.7%
5.45M▲ 197.8%
1.81M▼ 66.8%
70.66M▲ 3808.0%
48.83M▼ 30.9%
26.48M▼ 45.8%
12.18M▼ 54.0%
11.28M▼ 7.4%
Asset Turnover---------
Asset Growth %-45.39%-63.75%197.84%-66.85%3807.96%-30.9%-45.77%-53.98%-7.39%
Total Current Liabilities1.74M3.51M5.04M5.58M7.98M7.55M6.66M6.54M7.35M
Accounts Payable00003.37M4.41M4.96M4.14M5.58M
Days Payables Outstanding---------
Short-Term Debt225K234K244.3K212K2.31M1.35M122K138K106K
Deferred Revenue (Current)000000000
Other Current Liabilities299K505K1.93M5.37M590.59K-1.34M-113K-124K-94K
Current Ratio2.89x0.52x1.08x0.21x8.79x6.45x3.64x1.12x1.02x
Quick Ratio2.89x0.52x1.08x0.21x8.79x6.45x3.64x1.12x1.02x
Cash Conversion Cycle---------
Total Non-Current Liabilities1.44M3.01M3.11M411K290K0243K109K0
Long-Term Debt000000000
Capital Lease Obligations0000289.79K0243K109K0
Deferred Tax Liabilities000000000
Other Non-Current Liabilities1.44M3.01M3.11M411K2070000
Total Liabilities1.74M3.51M5.04M5.99M8.27M7.55M6.91M6.65M7.35M
Total Debt225K234K244.3K623K555K1.35M365K247K106K
Net Debt-4.48M186K-3.94M470K-65.27M-42.19M-17.76M-936K-3.62M
Debt / Equity0.07x-0.60x-0.01x0.03x0.02x0.04x0.03x
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage-809.78x-916.22x-827.33x-106.48x-87.58x-155.53x-2083.71x-1798.40x-2632.33x
Total Equity
3.31M▲ 0%
-1.68M▼ 150.8%
409.01K▲ 124.3%
-4.18M▼ 1122.0%
62.39M▲ 1592.5%
41.28M▼ 33.8%
19.57M▼ 52.6%
5.54M▼ 71.7%
3.94M▼ 28.9%
Equity Growth %-61.03%-150.78%124.3%-1121.97%1592.49%-33.83%-52.59%-71.71%-28.9%
Book Value per Share0.06-0.030.01-0.061.280.840.390.110.07
Total Shareholders' Equity3.31M-1.68M409.01K-4.18M45.71M41.28M19.57M5.54M3.94M
Common Stock2.83M3.75M6.77M4.1M97K102K102K103K111K
Retained Earnings11.04M-29.75M-39.9M-43.15M-84.65M-108.06M-116.26M-133.68M-144.83M
Treasury Stock000000-1.32M-1.57M0
Accumulated OCI-8K-19K-30.73K-35K-52K119.15M115.57M117.06M116.99M
Minority Interest000000000

TLSA Cash Flow Statement

Tiziana Life Sciences Ltd (TLSA) cash flow — operating, investing & free cash flow history

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24
Cash from Operations-5.62M-5.68M-3.63M-5.29M-8.76M-16.13M-15.99M-12.42M-1.22M
Operating CF Margin %---------
Operating CF Growth %1.43%-1.16%36.1%-45.78%-65.48%-84.22%0.88%22.31%90.18%
Net Income-7.92M-6.57M-6.26M-7.26M-19.17M-17.36M-12.55M-14M-9.48M
Depreciation & Amortization8.79K10.68K12.62K194.77K65.93K104.52K41.57K75.97K99.09K
Stock-Based Compensation000000000
Deferred Taxes000000000
Other Non-Cash Items1.35M-895.98K1.08M1.55M10.56M1.7M-2.53M2.75M8.6M
Working Capital Changes951.66K1.78M1.53M223.59K-215.69K-573.01K-948.89K-1.25M-441.1K
Change in Receivables038.83K-142K-99.37K-342.85K317.27K-127.17K-1.14M-1.11M
Change in Inventory000000000
Change in Payables000000000
Cash from Investing-276.93K-9700-2.98K-93.25K96.36K-3.26M-991.57K-56.73K
Capital Expenditures-38.46K-9700-2.98K-93.25K-16.31K00-15.18K
CapEx % of Revenue---------
Acquisitions000000000
Investments---------
Other Investing00000112.67K-1.08M-200.21K10.45K
Cash from Financing1.28M1.16M7.96M1.31M54.12M-17.05K-44.84K31.65K3.6M
Debt Issued (Net)779.13K0000000-141K
Equity Issued (Net)497.81K1000K1000K1000K1000K95.63K0125.83K1000K
Dividends Paid000000000
Share Repurchases000000000
Other Financing000-156.02K-203.45K-112.67K-44.84K-94.17K28.33K
Net Change in Cash
-5.95M▲ 0%
-4.33M▲ 27.3%
4.13M▲ 195.4%
-3.97M▼ 196.2%
48.26M▲ 1314.4%
-17.59M▼ 136.4%
-19.62M▼ 11.5%
-13.4M▲ 31.7%
2.03M▲ 115.1%
Free Cash Flow
-5.65M▲ 0%
-5.68M▼ 0.5%
-3.63M▲ 36.1%
-5.29M▼ 45.9%
-8.76M▼ 65.4%
-16.15M▼ 84.4%
-15.99M▲ 1.0%
-12.42M▲ 22.3%
-1.23M▲ 90.1%
FCF Margin %---------
FCF Growth %0.75%-0.49%36.11%-45.86%-65.43%-84.36%0.98%22.31%90.06%
FCF per Share-0.11-0.10-0.05-0.08-0.18-0.33-0.31-0.24-0.02
FCF Conversion (FCF/Net Income)0.78x0.84x0.58x0.72x0.34x0.69x1.04x0.70x0.10x
Interest Paid000000000
Taxes Paid000000000

TLSA Key Ratios

Tiziana Life Sciences Ltd (TLSA) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-167.92%-121.98%-830.17%-1540.08%--89.79%-45.18%-50.61%-140.92%-250.49%
Return on Invested Capital (ROIC)-------4572.49%-966.81%-420.58%-481.72%
Debt / Equity0.03x0.07x-0.60x-0.01x0.03x0.02x0.04x0.03x
Interest Coverage-478.56x-809.78x-916.22x-827.33x-106.48x-87.58x-155.53x-2083.71x-1798.40x-2632.33x
FCF Conversion0.66x0.78x0.84x0.58x0.72x0.34x0.69x1.04x0.70x0.10x

TLSA Frequently Asked Questions

Tiziana Life Sciences Ltd (TLSA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Tiziana Life Sciences Ltd (TLSA) grew revenue by 0.0% over the past year. Growth has been modest.

Tiziana Life Sciences Ltd (TLSA) reported a net loss of $34.2M for fiscal year 2024.

Dividend & Returns

Tiziana Life Sciences Ltd (TLSA) has a return on equity (ROE) of -250.5%. Negative ROE indicates the company is unprofitable.

Tiziana Life Sciences Ltd (TLSA) had negative free cash flow of $13.6M in fiscal year 2024, likely due to heavy capital investments.

Explore More TLSA

Tiziana Life Sciences Ltd (TLSA) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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