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ARCTArcturus Therapeutics Holdings Inc.
$13.30$378M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
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ARCT logo

Arcturus Therapeutics Holdings Inc.

ARCT
NASDAQ · Biotechnology
$13.30
At close - Sep 23, 4:00 PM EDT - USD
Market Cap$378M
P/E-5.5x
52W High$24.17
Volume1.03M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Cash Burn Consumes Reserves Amid Depleted Milestone Revenue

Arcturus Therapeutics' financial profile is defined by a high-intensity R&D burn rate consuming a finite cash reserve, with revenue exhibiting extreme lumpiness and lacking visibility. The company's liquidity buffer appears adequate on a headline basis with a ...

GrowthDecelerating
ProfitabilityNegative
ValuationReview
TechnicalsHealthy
Explore valuation models
MARKET ACTION

ARCT price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

10/12 Beats

EPS beat 10 of last 12 quarters

02

Valuation risk

-113% Peers

P/E is 113% below peer median

03

Market leadership

RS 98 · Leader

High momentum (Outperforming 98% of market)

04

Healthy Uptrend

Uptrend

Price > 50DMA > 200DMA

Next CatalystConfirmed earnings · Nov 9

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
ARCT+112.80%
S&P 500 (^GSPC)+12.39%
1-Year Return
ARCT-34.35%
S&P 500 (^GSPC)+15.77%
3-Year Return
ARCT-49.33%
S&P 500 (^GSPC)+72.85%
5-Year Return
ARCT-75.62%
S&P 500 (^GSPC)+60.07%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E5Y Low
-5.5x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-5.5x
48.5x
0th· Low
EV/EBITDA
N/A
11.8x
N/A
Price/FCF
N/A
18.9x
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
No DCF Model AvailableIntrinsic value modeling is not supported for this equity.

Growth & profitability

Annual revenue & EPS trend
Revenue
$67M-51.4% YoY
Net income
-$66M+18.7% YoY
Free cash flow
-$74M-23.0% YoY
Operating margin
-111.5%-42.4 pts YoY
ROIC (TTM)-277.1%
Avg ROIC 5Y-
ROE (TTM)-28.9%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate10/12 (83%)
Revenue Beat Rate6/12 (50%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 6, 2026
-$0.84+15.7%
vs -$1.00
$3M-4.8%
vs $3M
Q2 2026
May 7, 2026
-$0.95+7.4%
vs -$1.03
$2M-67.3%
vs $6M
Q2 2026
Mar 3, 2026
-$1.03-12.0%
vs -$0.92
$7M-54.7%
vs $16M
Q4 2025
Nov 10, 2025
-$0.49+38.7%
vs -$0.80
$17M+7.0%
vs $16M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
GuruFocus·5d ago
Arcturus Therapeutics to Present Ornithine Transcarbamylase (OTC) Deficiency Phase 2 Clinical Data and Provide Update on mRNA Liver Therapeutics Platform

Arcturus Therapeutics Holdings Inc. (the “Company”, “Arcturus”, Nasdaq: ARCT), a messenger RNA medicines company focused on the development of liver and

Business Wire·5d ago
Arcturus Therapeutics to Present Ornithine Transcarbamylase (OTC) Deficiency Phase 2 Clinical Data and Provide Update on mRNA Liver Therapeutics Platform

SAN DIEGO--(BUSINESS WIRE)---- $ARCT #65Roses--Arcturus Therapeutics Holdings Inc. (the “Company”, “Arcturus”, Nasdaq: ARCT), a messenger RNA medicines company focused on the development of liver and respiratory rare disease therapeutics, today announced that it will host a virtual presentation on Wednesday, September 23, 2026, at 4:30 p.m. ET. The presentation will provide an overview of the ARCT-810 Phase 2 clinical program for Ornithine transcarbamylase (OTC) deficiency and Arcturus' mRNA liver therapeutics pl.

Seeking Alpha·Sep 9, 2026
Arcturus Therapeutics Holdings Inc. (ARCT) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

Arcturus Therapeutics Holdings Inc. (ARCT) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

Defense World·Sep 4, 2026
56,895 Shares in Arcturus Therapeutics Holdings Inc. $ARCT Bought by Hsbc Holdings PLC

Hsbc Holdings PLC acquired a new position in shares of Arcturus Therapeutics Holdings Inc. (NASDAQ: ARCT) during the second quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission. The fund acquired 56,895 shares of the biotechnology company's stock, valued at approximately $394,000. Hsbc Holdings PLC

Filtered for Arcturus Therapeutics Holdings Inc.More Headlines
04

Compare before deciding

Benchmark ARCT against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Arcturus Therapeutics Holdings Inc. (ARCT)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ARCT logoARCTArcturus Therapeutics Holdings Inc.Current
$13.30$378.03M-5.54-51.43%-97.86%-28.92%—
MRNA logoMRNAModerna, Inc.
$182.11$72.26B-25.08-39.23%-141.43%-39.2%—
BNTX logoBNTXBioNTech SE
$98.46$24.73B-19.180.2%-64.02%-9.13%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$12.33$1.38B-3.2416.92%-672.16%-57.79%—
CRSP logoCRSPCRISPR Therapeutics AG
$55.76$5.38B-8.62-89.97%-3368.72%-24.39%—
BEAM logoBEAMBeam Therapeutics Inc.
$24.37$2.51B-30.09120.01%-54.75%-7.7%—

Compare ARCT vs Peers

Arcturus Therapeutics Holdings Inc. (ARCT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs MRNA

Most directly comparable listed peer for ARCT.

Scale Benchmark

vs TMO

Larger-name benchmark to compare ARCT against a more recognizable public peer.

Peer Set

Compare Top 5

vs MRNA, BNTX, NTLA, CRSP

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

ARCT SEC Filings & Documents

Arcturus Therapeutics Holdings Inc. (ARCT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jul 2, 2026·SEC

Material company update

Jun 5, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 3, 2026·SEC

FY 2025

Mar 6, 2025·SEC

FY 2024

Mar 14, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 12, 2025·SEC

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ARCT Frequently Asked Questions

Arcturus Therapeutics Holdings Inc. (ARCT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Arcturus Therapeutics Holdings Inc.'s revenue?

Arcturus Therapeutics Holdings Inc. (ARCT) reported $23.8M in revenue for fiscal year 2025.

How fast is Arcturus Therapeutics Holdings Inc. growing?

Arcturus Therapeutics Holdings Inc. (ARCT) saw revenue decline by 51.4% over the past year.

Is ARCT profitable?

Arcturus Therapeutics Holdings Inc. (ARCT) reported a net loss of $93.3M for fiscal year 2025.

Dividend & Returns
What is ARCT's return on equity?

Arcturus Therapeutics Holdings Inc. (ARCT) has a return on equity (ROE) of -28.9%. Negative ROE indicates the company is unprofitable.

What is Arcturus Therapeutics Holdings Inc.'s free cash flow?

Arcturus Therapeutics Holdings Inc. (ARCT) had negative free cash flow of $92.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ARCT back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →