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ATXI logoAvenue Therapeutics, Inc.(ATXI)Earnings, Financials & Key Ratios

ATXI•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Specialty Pharma
AboutAvenue Therapeutics, Inc., a specialty pharmaceutical company, develops and commercializes products primarily for use in the acute/intensive care hospital setting. Its product candidate is intravenous Tramadol, a synthetic dual-acting opioid, which is in Phase III clinical trials for the treatment of post-operative acute pain. The company was incorporated in 2015 and is based in New York, New York.Show more
  • Revenue$1M
  • EBITDA-$3M+71.9%
  • Net Income-$3M+75.0%
  • EPS (Diluted)-0.93-3.3%
  • Gross Margin100%
  • EBITDA Margin-234.05%
  • Operating Margin-234.05%
  • Net Margin-207.19%
  • ROE-157.75%+83.0%

ATXI Key Insights

Avenue Therapeutics, Inc. (ATXI) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Share count reduced 75.8% through buybacks
  • ✓Trading at only 0.5x book value

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 17 (bottom 17%)
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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ATXI Price & Volume

Avenue Therapeutics, Inc. (ATXI) stock price & volume — 10-year historical chart

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ATXI Growth Metrics

Avenue Therapeutics, Inc. (ATXI) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM87.17%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM88.04%

Return on Capital

10 Years-395.43%
5 Years-437.45%
3 Years-606.36%
Last Year-178.2%

ATXI Recent Earnings

Avenue Therapeutics, Inc. (ATXI) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (50%)
Q2 2026Latest
May 8, 2026
Metric
Actual
Est
EPS
$0.21+99.6%
$56.25
Rev
—
—
Q2 2026
Mar 30, 2026
Metric
Actual
Est
EPS
$0.22+99.6%
$56.25
Rev
—
—
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.21
—
Rev
—
—
Q3 2025
Aug 14, 2025
Metric
Actual
Est
EPS
$0.11
—
Rev
$1M
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 8, 2026
$0.21vs $56.25+99.6%
—
Q2 2026Mar 30, 2026
$0.22vs $56.25+99.6%
—
Q4 2025Nov 13, 2025
$0.21
—
Q3 2025Aug 14, 2025
$0.11
$1M
Based on last 12 quarters of dataView full earnings history →

ATXI Peer Comparison

Avenue Therapeutics, Inc. (ATXI) competitors in Commercial Specialty Pharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
PCRX logoPCRXPacira BioSciences, Inc.Direct Competitor878.35M22.33139.563.63%1.27%1.31%0.66
COLL logoCOLLCollegium Pharmaceutical, Inc.Direct Competitor1.09B33.5419.3923.62%9.41%26.74%3.12
MNKD logoMNKDMannKind CorporationProduct Competitor1.22B3.9419722.23%-6.63%
XTLB logoXTLBXTL Biopharmaceuticals Ltd.Product Competitor279.46K2.54-0.26-227.72%-25.53%0.03
NKTR logoNKTRNektar TherapeuticsProduct Competitor1.19B60.98-6.27-43.89%-284.18%-87%1.66
PRGO logoPRGOPerrigo Company plcProduct Competitor1.42B10.25-1.00-2.75%-43.5%-50.65%1.35
INVA logoINVAInnoviva, Inc.Supply Chain1.66B22.496.8218.52%118.91%47.59%0.23
MCK logoMCKMcKesson CorporationSupply Chain90.23B750.6319.5612.36%1.18%

Compare ATXI vs Peers

Avenue Therapeutics, Inc. (ATXI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PCRX

Most directly comparable listed peer for ATXI.

Scale Benchmark

vs MCK

Larger-name benchmark to compare ATXI against a more recognizable public peer.

Peer Set

Compare Top 5

vs PCRX, COLL, MNKD, XTLB

ATXI Income Statement

Avenue Therapeutics, Inc. (ATXI) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
000000001.4M1.4M
Revenue Growth %
----------
Cost of Goods Sold
0000000000
COGS % of Revenue
----------
Gross Profit
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
1.4M▲ 0%
0▲ 0%
Gross Margin %
--------100%0%
Gross Profit Growth %
----------
Operating Expenses
6.7M21.82M26.27M5.21M3.74M8.04M14.54M11.28M4.69M3.5M
OpEx % of Revenue
--------334.05%-
Selling, General & Admin
3.62M4.12M3.07M2.35M2.48M5.34M4.18M4.64M3.65M2.67M
SG&A % of Revenue
--------260.19%-
Research & Development
7.8M17.7M23.19M2.87M1.25M2.7M10.36M6.64M1.04M826K
R&D % of Revenue
--------73.86%-
Other Operating Expenses
-99K175K00000000
Operating Income
-11.42M▲ 0%
-21.82M▼ 91.0%
-26.27M▼ 20.4%
-5.21M▲ 80.2%
-3.74M▲ 28.3%
-8.04M▼ 115.2%
-14.54M▼ 80.8%
-11.28M▲ 22.4%
-3.29M▲ 70.9%
-2.1M▲ 0%
Operating Margin %
---------234.05%-149.29%
Operating Income Growth %
-380.48%-91.02%-20.39%80.15%28.29%-115.17%-80.78%22.4%70.88%-
EBITDA
00-25.91M-5.15M0-2.44M0-11.7M-3.29M-2.06M
EBITDA Margin %
---------234.05%-146.37%
EBITDA Growth %
---80.12%100%-100%-71.9%77.79%
D&A (Non-Cash Add-back)
11.42M21.82M003.74M014.54M000
EBIT
-11.88M-21.55M-25.91M-5.15M-3.73M-2.44M-10.49M-11.7M-3.29M-2.06M
Net Interest Income
-287K0357K62K7K-1.14M126K176K121K107K
Interest Income
88K93K357K62K7K20K126K176K121K107K
Interest Expense
375K00001.16M0000
Other Income/Expense
-837K268K357K62K7K4.44M4.05M-413K339K311K
Pretax Income
-12.26M▲ 0%
-21.55M▼ 75.8%
-25.91M▼ 20.2%
-5.15M▲ 80.1%
-3.73M▲ 27.6%
-3.6M▲ 3.4%
-10.49M▼ 191.1%
-11.7M▼ 11.5%
-2.95M▲ 74.8%
-1.78M▲ 0%
Pretax Margin %
---------209.9%-127.07%
Income Tax
0-268K00000000
Effective Tax Rate %
0%1.24%0%0%0%0%0%0%0%0%
Net Income
-12.26M▲ 0%
-21.55M▼ 75.8%
-25.91M▼ 20.2%
-5.15M▲ 80.1%
-3.73M▲ 27.6%
-3.55M▲ 4.8%
-10.38M▼ 192.1%
-11.65M▼ 12.3%
-2.91M▲ 75.0%
-1.75M▲ 0%
Net Margin %
---------207.19%-124.79%
Net Income Growth %
-285.84%-75.79%-20.23%80.12%27.57%4.8%-192.15%-12.29%75.03%87.17%
Net Income (Continuing)
-12.26M-21.55M-25.91M-5.15M-3.73M-3.6M-10.49M-11.7M-2.95M-1.77M
Discontinued Operations
0000000000
Minority Interest
00000-639K-928K-941K00
EPS (Diluted)
-27.71▲ 0%
-31.17▼ 12.5%
-24.38▲ 21.8%
-4.65▲ 80.9%
-3.29▲ 29.2%
-121.91▼ 3605.5%
-73.48▲ 39.7%
-0.90▲ 98.8%
-0.93▼ 3.3%
-0.53▲ 0%
EPS Growth %
-414.1%-12.49%21.78%80.93%29.25%-3605.47%39.73%98.78%-3.33%88.04%
EPS (Basic)
-27.71-31.17-24.38-4.65-3.29-121.91-73.60-0.90-0.93-
Diluted Shares Outstanding
442.33K682.61K1.05M1.1M1.13M29.14K141.22K12.95M3.13M3.29M
Basic Shares Outstanding
442.33K682.61K1.05M1.1M1.13M29.14K141K12.95M3.13M3.29M
Dividend Payout Ratio
----------

ATXI Balance Sheet

Avenue Therapeutics, Inc. (ATXI) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
22.17M4.53M8.91M3.25M3.96M6.84M1.85M2.67M2.85M2.42M
Cash & Short-Term Investments
21.78M2.67M8.74M3.13M3.76M6.71M1.78M2.59M2.85M2.42M
Cash Only
11.78M2.67M8.74M3.13M3.76M6.71M1.78M2.59M2.85M2.42M
Short-Term Investments
10M000000000
Accounts Receivable
000090K00000
Days Sales Outstanding
---------51.99
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
01.7M0000078K00
Total Non-Current Assets
01.85M170K113K0067K000
Property, Plant & Equipment
0000000000
Fixed Asset Turnover
----------
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
0000000000
Other Non-Current Assets
01.85M170K113K0067K000
Total Assets
22.17M▲ 0%
4.53M▼ 79.6%
8.91M▲ 97.0%
3.25M▼ 63.6%
3.96M▲ 22.0%
6.84M▲ 72.9%
1.85M▼ 73.0%
2.67M▲ 44.4%
2.93M▲ 9.7%
2.47M▲ 0%
Asset Turnover
--------0.48x0.42x
Asset Growth %
11153.81%-79.59%97.02%-63.6%22.03%72.85%-72.97%44.43%9.69%3.69%
Total Current Liabilities
2.79M5.16M2.12M886K509K3.58M1.2M816K1.1M1.27M
Accounts Payable
1.54M3.09M354K172K304K150K401K155K00
Days Payables Outstanding
----------
Short-Term Debt
0000000000
Deferred Revenue (Current)
0000000000
Other Current Liabilities
001M024K2.61M784K34K1.1M1.27M
Current Ratio
7.95x0.88x4.22x3.66x7.78x1.91x1.55x3.27x2.60x1.90x
Quick Ratio
7.95x0.88x4.22x3.66x7.78x1.91x1.55x3.27x2.60x1.90x
Cash Conversion Cycle
---------51.99
Total Non-Current Liabilities
0000000000
Long-Term Debt
0000000000
Capital Lease Obligations
0000000000
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
0000000000
Total Liabilities
2.79M5.16M2.12M886K509K3.58M1.2M816K1.1M1.27M
Total Debt
0000000000
Net Debt
-11.78M-2.67M-8.74M-3.13M-3.76M-6.71M-1.78M-2.59M-2.85M-2.42M
Debt / Equity
---------0.00x
Debt / EBITDA
----------0.00x
Net Debt / EBITDA
---------1.18x
Interest Coverage
-31.69x-----2.11x----
Total Equity
19.38M▲ 0%
-631K▼ 103.3%
6.8M▲ 1177.7%
2.36M▼ 65.3%
3.45M▲ 46.3%
3.27M▼ 5.4%
654K▼ 80.0%
1.86M▲ 183.8%
1.83M▼ 1.3%
1.2M▲ 0%
Equity Growth %
334.97%-103.26%1177.65%-65.31%46.29%-5.36%-79.98%183.79%-1.29%-36.51%
Book Value per Share
43.81-0.926.492.143.05112.104.630.140.590.36
Total Shareholders' Equity
19.38M-631K6.8M2.36M3.45M3.9M1.58M2.8M1.83M1.2M
Common Stock
1K1K2K2K003K000
Retained Earnings
-20.66M-42.21M-68.12M-73.27M-77M-80.55M-90.93M-102.58M-105.49M-106.18M
Treasury Stock
0000000000
Accumulated OCI
1.1M000000000
Minority Interest
00000-639K-928K-941K00

ATXI Cash Flow Statement

Avenue Therapeutics, Inc. (ATXI) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-6.8M-18.22M-26.26M-4.61M-3.75M-7.6M-9.45M-9.03M-1.83M-1.08M
Operating CF Margin %
---------130.56%-
Operating CF Growth %
-316.79%-167.8%-44.15%82.43%18.71%-102.56%-24.42%4.5%79.69%256.73%
Net Income
-12.26M-21.55M-25.91M-5.15M-3.73M-3.6M-10.38M-11.7M-2.91M-1.75M
Depreciation & Amortization
174K000000000
Stock-Based Compensation
604K1.54M1.84M710K442K649K906K1.24M665K541K
Deferred Taxes
277K000000000
Other Non-Cash Items
2.32M412K61K00-5.05M310K1.25M111K833K
Working Capital Changes
2.08M1.79M-2.25M-172K-461K408K-290K179K300K-675K
Change in Receivables
0000-90K90K0000
Change in Inventory
0000000000
Change in Payables
2.23M1.13M-3.23M-229K00-360K0298K-437K
Cash from Investing
-10M10M0-1M00-3M000
Capital Expenditures
000-1M000000
CapEx % of Revenue
---------0%
Acquisitions
0000000000
Investments
----------
Other Investing
-10K-10M0000-3M000
Cash from Financing
28.39M-895K32.33M04.38M10.54M7.53M9.84M2.09M0
Debt Issued (Net)
-3M000000000
Equity Issued (Net)
37.95M035M05.04M10.39M7.53M1.62M2.09M0
Dividends Paid
0000000000
Share Repurchases
00000-1.1M0000
Other Financing
-6.56M-895K-2.67M0-663K148K1K8.21M00
Net Change in Cash
11.59M▲ 0%
-9.11M▼ 178.6%
6.07M▲ 166.7%
-5.61M▼ 192.4%
631K▲ 111.2%
2.94M▲ 366.7%
-4.92M▼ 267.2%
811K▲ 116.5%
261K▼ 67.8%
-1.08M▲ 0%
Free Cash Flow
-6.8M▲ 0%
-18.22M▼ 167.8%
-26.26M▼ 44.2%
-5.61M▲ 78.6%
-3.75M▲ 33.2%
-7.6M▼ 102.6%
-12.45M▼ 63.9%
-9.03M▲ 27.5%
-1.83M▲ 79.7%
-1.08M▲ 0%
FCF Margin %
---------130.56%-77.28%
FCF Growth %
-316.79%-167.8%-44.15%78.62%33.19%-102.56%-63.92%27.51%79.69%84.7%
FCF per Share
-15.38-26.69-25.06-5.10-3.31-260.72-88.17-0.70-0.59-0.33
FCF Conversion (FCF/Net Income)
0.55x0.85x1.01x0.90x1.01x2.14x0.91x0.77x0.63x0.62x
Interest Paid
0000000000
Taxes Paid
0000000000

ATXI Key Ratios

Avenue Therapeutics, Inc. (ATXI) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-220.23%-229.86%-839.94%-112.48%-128.43%-105.76%-529.44%-928.45%-157.75%-85.83%
Return on Invested Capital (ROIC)
-340.79%-761.73%-------151.81%
Gross Margin
--------100%0%
Net Margin
---------207.19%-124.79%
Debt / Equity
---------0.00x
Interest Coverage
-31.69x-----2.11x----
FCF Conversion
0.55x0.85x1.01x0.90x1.01x2.14x0.91x0.77x0.63x0.62x
Related:ATXI Dividend History·ATXI Revenue History·ATXI Price History·ATXI P/E History·ATXI Financial Ratios·ATXI Institutional Holders

ATXI SEC Filings & Documents

Avenue Therapeutics, Inc. (ATXI) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Feb 23, 2026·SEC

Material company update

Dec 31, 2025·SEC

Material company update

Nov 18, 2025·SEC

10-K Annual Reports

3
FY 2026

Mar 30, 2026·SEC

FY 2025

Mar 31, 2025·SEC

FY 2024

Mar 18, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 8, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 14, 2025·SEC

ATXI Frequently Asked Questions

Avenue Therapeutics, Inc. (ATXI) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Avenue Therapeutics, Inc. (ATXI) reported $1.4M in revenue for fiscal year 2025.

Avenue Therapeutics, Inc. (ATXI) grew revenue by 0.0% over the past year. Growth has been modest.

Avenue Therapeutics, Inc. (ATXI) reported a net loss of $1.8M for fiscal year 2025.

Dividend & Returns

Avenue Therapeutics, Inc. (ATXI) has a return on equity (ROE) of -157.8%. Negative ROE indicates the company is unprofitable.

Avenue Therapeutics, Inc. (ATXI) had negative free cash flow of $1.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ATXI back in 2015?

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