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GHGuardant Health, Inc.
$177.16$23.5B
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GH logo

Guardant Health, Inc.

GH
NASDAQ · Diagnostics & Research
$177.16
At close - Sep 22, 4:00 PM EDT - USD
Market Cap$23.49B
P/E-53.4x
52W High$183.42
Volume2.21M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Revenue Surge Masks Persistent Cash Burn

Guardant Health is experiencing accelerating revenue growth, with Q2 2026 revenue up 44.3% year-over-year to $335.0M, driven by strong adoption of its liquid biopsy tests. Gross margins have expanded to 65.4%, but the company remains deeply unprofitable, with ...

GrowthAccelerating
ProfitabilityWeak
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

GH price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

3/12 Beats

EPS beat 3 of last 12 quarters

02

Valuation risk

-222% Peers

P/E is 222% below peer median

03

Market leadership

RS 94 · Leader

High momentum (Outperforming 94% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystEstimated earnings · Oct 30
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

Revenue growth accelerated to 44.3% year-over-year in Q2 2026, reaching $335.0M, while gross margin improved to 65.4%, but operating margin remained deeply negative at -38.5%.

Analyst Consensus+12.6% target
Buy(31 analysts)
30 Buy0 Hold1 Sell

The Bull Case

Upside Catalysts

FDA-approved Shield test adoption

Guardant Health's Shield blood test was added to the American Cancer Society's colorectal cancer screening guidelines, enhancing its market potential for average-risk adults.

Companion diagnostic approval

The FDA approved Guardant360 CDx as a companion diagnostic for VEPPANU, enabling blood-based detection of ESR1 mutations in ER-positive breast cancer.

Real-world evidence impact

Guardant's InfinityAI and Guardant360 platforms provided real-world evidence supporting Japan's approval of ENHERTU for HER2-positive solid tumors, showcasing its clinical utility.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 9/23/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
GH+74.13%
S&P 500 (^GSPC)+13.20%
1-Year Return
GH+196.35%
S&P 500 (^GSPC)+15.98%
3-Year Return
GH+583.22%
S&P 500 (^GSPC)+86.94%
5-Year Return
GH+34.96%
S&P 500 (^GSPC)+78.49%

Growth & profitability

Annual revenue & EPS trend
Revenue
$982M+32.9% YoY
Net income
-$416M+4.6% YoY
Free cash flow
-$233M+15.2% YoY
Operating margin
-44.4%+15.6 pts YoY
ROIC (TTM)-34.4%
Avg ROIC 5Y-
ROE (TTM)-
Piotroski Score5 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate3/12 (25%)
Revenue Beat Rate12/12 (100%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Jul 30, 2026
-$0.90-18.1%
vs -$0.76
$335M+6.6%
vs $314M
Q2 2026
May 7, 2026
-$0.85-5.5%
vs -$0.81
$302M+8.1%
vs $279M
Q1 2026
Feb 19, 2026
-$1.00-30.4%
vs -$0.77
$281M+3.2%
vs $272M
Q4 2025
Oct 29, 2025
-$0.74+6.3%
vs -$0.79
$265M+12.6%
vs $236M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Investors Business Daily·2d ago
AI-Fueled Precision Oncology Firm Guardant Health Is In Focus. Here's Why.

Earning a spot on the IBD Leaderboard and IBD 50, Guardant Health stress tests a breakout.

Defense World·2d ago
Guardant Health (NASDAQ:GH) versus InfuSystem (NYSE:INFU) Critical Review

Guardant Health (NASDAQ: GH - Get Free Report) and InfuSystem (NYSE: INFU - Get Free Report) are both healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their analyst recommendations, dividends, risk, institutional ownership, profitability, valuation and earnings. Earnings and Valuation This table compares Guardant Health and

Defense World·3d ago
Guardant Health (NASDAQ:GH) Director Sells $144,550.00 in Stock

Guardant Health, Inc. (NASDAQ: GH - Get Free Report) Director Alex Azar II sold 826 shares of Guardant Health stock in a transaction dated Wednesday, September 16th. The shares were sold at an average price of $175.00, for a total value of $144,550.00. Following the completion of the sale, the director owned 825 shares of the

Seeking Alpha·Sep 15, 2026
Guardant Health, Inc. (GH) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Guardant Health, Inc. (GH) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Filtered for Guardant Health, Inc.More Headlines
04

Compare before deciding

Benchmark GH against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Guardant Health, Inc. (GH)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
GH logoGHGuardant Health, Inc.Current
$177.16$23.49B-53.3632.88%-42.39%——
EXAS logoEXASExact Sciences Corporation
$104.91$20.02B-95.3717.69%-6.4%-8.66%—
ILMN logoILMNIllumina, Inc.
$247.46$37.44B45.41-0.78%18.36%31.08%—
NTRA logoNTRANatera, Inc.
$390.90$55.98B-257.1735.9%-7.11%-11.73%—
FDMT logoFDMT4D Molecular Therapeutics, Inc.
$15.88$830.15M-6.56—-194.74%-41.33%—
CGEN logoCGENCompugen Ltd.
$2.49$235.44M6.55161.14%47.55%42.57%—

Compare GH vs Peers

Guardant Health, Inc. (GH) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs EXAS

Most directly comparable listed peer for GH.

Scale Benchmark

vs TMO

Larger-name benchmark to compare GH against a more recognizable public peer.

Peer Set

Compare Top 5

vs EXAS, ILMN, NTRA, FDMT

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

GH SEC Filings & Documents

Guardant Health, Inc. (GH) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 30, 2026·SEC

Material company update

Jun 18, 2026·SEC

Material company update

May 7, 2026·SEC

10-K Annual Reports

1
FY 2026

Feb 19, 2026·SEC

10-Q Quarterly Reports

5
FY 2026

Jul 30, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Oct 29, 2025·SEC

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GH Frequently Asked Questions

Guardant Health, Inc. (GH) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Guardant Health, Inc.'s revenue?

Guardant Health, Inc. (GH) reported $1.18B in revenue for fiscal year 2025. This represents a 4586% increase from $25.2M in 2016.

How fast is Guardant Health, Inc. growing?

Guardant Health, Inc. (GH) grew revenue by 32.9% over the past year. This is strong growth.

Is GH profitable?

Guardant Health, Inc. (GH) reported a net loss of $453.4M for fiscal year 2025.

Dividend & Returns
What is Guardant Health, Inc.'s free cash flow?

Guardant Health, Inc. (GH) had negative free cash flow of $240.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in GH back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →