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HALO logoHalozyme Therapeutics, Inc.(HALO)Earnings, Financials & Key Ratios

HALO•NASDAQ
$65.87
$7.76B mkt cap·25.7× P/E·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Delivery Technology Platforms
AboutHalozyme Therapeutics, Inc. operates as a biopharma technology platform company in the United States, Switzerland, Ireland, Belgium, Japan, and internationally. The company's products are based on the ENHANZE drug delivery technology, a patented recombinant human hyaluronidase enzyme (rHuPH20) that enables the subcutaneous delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids. Its flagship product is Hylenex recombinant, a formulation of rHuPH20 to facilitate subcutaneous fluid administration for achieving hydration to enhance the dispersion and absorption of other injected drugs in subcutaneous urography and to improve resorption of radiopaque agents. The company also develops Perjeta; RITUXAN HYCELA and MabThera SC for the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia (CLL); RITUXAN SC for patients with CLL; and HYQVIA for the treatment of immunodeficiency disorders. In addition, it is developing Tecentriq for non-small cell lung cancer; OCREVUS for multiple sclerosis; DARZALEX for the treatment of patients with amyloidosis, smoldering myeloma, and multiple myeloma; nivolumab for the treatment of solid tumors; ARGX-113, a human neonatal Fc receptor; ARGX-117 to treat autoimmune diseases; and BMS-986179, an anti-CD-73 antibody. The company has collaborations with F. Hoffmann-La Roche, Ltd.; Hoffmann-La Roche, Inc.; Baxalta US Inc.; Baxalta GmbH; Pfizer Inc.; Janssen Biotech, Inc.; AbbVie, Inc.; Eli Lilly and Company; Bristol-Myers Squibb Company; Alexion Pharma Holding; ARGENX BVBA; Horizon Therapeutics plc; National Institute of Allergy and Infectious Diseases; Centre for the AIDS Programme of Research in South Africa; and ViiV Healthcare Limited for small and large molecule targets for the treatment and prevention of HIV. Halozyme Therapeutics, Inc. was founded in 1998 and is based in San Diego, California.Show more
  • Revenue$1.4B+37.6%
  • EBITDA$904M+42.9%
  • Net Income$317M-28.6%
  • EPS (Diluted)2.56-25.4%
  • Gross Margin78.13%-7.3%
  • EBITDA Margin64.75%+3.9%
  • Operating Margin58.45%+7.6%
  • Net Margin22.69%-48.1%
  • ROE153.59%-22.6%
  • ROIC73.37%+185.5%
  • Interest Coverage45.03+47.8%
Technical→

HALO Key Insights

Halozyme Therapeutics, Inc. (HALO) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Excellent 3Y average ROE of 191.4%
  • ✓Strong 5Y profit CAGR of 19.7%
  • ✓FCF machine: 46.2% free cash flow margin
  • ✓High quality earnings: Operating CF exceeds net income
  • ✓Strong 5Y sales CAGR of 39.2%
  • ✓Share count reduced 4.3% through buybacks

✗Weaknesses

  • ✗Expensive at 167.2x book value

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

HALO Price & Volume

Halozyme Therapeutics, Inc. (HALO) stock price & volume — 10-year historical chart

Loading chart...

HALO Growth Metrics

Halozyme Therapeutics, Inc. (HALO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years26.32%
5 Years39.16%
3 Years28.38%
TTM37.55%

Profit CAGR

10 Years-
5 Years19.68%
3 Years16.17%
TTM-28.64%

EPS CAGR

10 Years-
5 Years22.98%
3 Years21.14%
TTM-27.41%

Return on Capital

10 Years14.1%
5 Years31.52%
3 Years29.86%
Last Year38.21%

HALO Recent Earnings

Halozyme Therapeutics, Inc. (HALO) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)●Beat Revenue 4/12 qtrs (33%)
Q1 2026Latest
Feb 17, 2026
EPS
$0.24
Est $2.15
-111.2%
Revenue
$452M
Est $436M
+3.7%
Q4 2025
Nov 3, 2025
EPS
$1.72
Est $1.63
+5.5%
Revenue
$354M
Est $447M
-20.7%
Q3 2025
Aug 5, 2025
EPS
$1.54
Est $1.23
+25.2%
Revenue
$326M
Est $331M
-1.5%
Q2 2025
May 6, 2025
EPS
$1.11
Est $0.95
+16.8%
Revenue
$265M
Est $281M
-5.7%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q1 2026LatestFeb 17, 2026
$0.24vs $2.15-111.2%
$452Mvs $436M+3.7%
Q4 2025Nov 3, 2025
$1.72vs $1.63+5.5%
$354Mvs $447M-20.7%
Q3 2025Aug 5, 2025
$1.54vs $1.23+25.2%
$326Mvs $331M-1.5%
Q2 2025May 6, 2025
$1.11vs $0.95+16.8%
$265Mvs $281M-5.7%
Based on last 12 quarters of dataView full earnings history →

HALO Peer Comparison

Halozyme Therapeutics, Inc. (HALO) competitors in Drug Delivery Technology Platforms — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ALNY logoALNYAlnylam Pharmaceuticals, Inc.Direct Competitor40.18B301.11129.2365.19%13.46%98.29%1.16%1.62
IONS logoIONSIonis Pharmaceuticals, Inc.Direct Competitor12.44B75.25-31.6233.87%-30.87%-58.57%5.35
ARWR logoARWRArrowhead Pharmaceuticals, Inc.Direct Competitor10.49B74.93-6141.80232.58%18.54%35.64%1.5%0.73
EXEL logoEXELExelixis, Inc.Direct Competitor11.28B44.4215.986.98%35.08%40.21%7.48%0.08
INVA logoINVAInnoviva, Inc.Direct Competitor1.69B22.656.8618.52%65.38%23.12%11.58%
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.62B26.06-7.92-4.26%-156.36%-68.97%0.16
ABBV logoABBVAbbVie Inc.Product Competitor364.63B206.1586.988.57%6.91%62.15%4.89%
AMGN logoAMGNAmgen Inc.Product Competitor177.87B329.5923.169.92%20.95%89.41%4.55%6.31

Compare HALO vs Peers

Halozyme Therapeutics, Inc. (HALO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ALNY

Most directly comparable listed peer for HALO.

Scale Benchmark

vs JNJ

Larger-name benchmark to compare HALO against a more recognizable public peer.

Peer Set

Compare Top 5

vs ALNY, IONS, ARWR, EXEL

HALO Income Statement

Halozyme Therapeutics, Inc. (HALO) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue316.61M151.86M195.99M267.59M443.31M660.12M829.25M1.02B1.4B
Revenue Growth %115.84%-52.04%29.06%36.53%65.67%48.91%25.62%22.44%37.55%
Cost of Goods Sold31.15M10.14M45.55M43.37M81.41M139.3M192.36M159.42M305.44M
COGS % of Revenue9.84%6.67%23.24%16.21%18.36%21.1%23.2%15.7%21.87%
Gross Profit
285.46M▲ 0%
141.73M▼ 50.4%
150.45M▲ 6.2%
224.23M▲ 49.0%
361.9M▲ 61.4%
520.81M▲ 43.9%
636.89M▲ 22.3%
855.91M▲ 34.4%
1.09B▲ 27.5%
Gross Margin %90.16%93.33%76.76%83.79%81.64%78.9%76.8%84.3%78.13%
Gross Profit Growth %151.54%-50.35%6.15%49.04%61.4%43.91%22.29%34.39%27.49%
Operating Expenses204.46M211.06M218.06M79.97M86M253.28M299.32M304.43M274.88M
OpEx % of Revenue64.58%138.98%111.26%29.89%19.4%38.37%36.09%29.98%19.68%
Selling, General & Admin53.82M60.8M77.25M45.74M50.32M143.53M149.18M154.34M193.39M
SG&A % of Revenue17%40.04%39.42%17.09%11.35%21.74%17.99%15.2%13.85%
Research & Development150.64M150.25M140.8M34.24M35.67M66.61M76.36M79.05M81.49M
R&D % of Revenue47.58%98.94%71.84%12.79%8.05%10.09%9.21%7.79%5.83%
Other Operating Expenses0000043.15M73.77M71.05M0
Operating Income
81M▲ 0%
-69.33M▼ 185.6%
-67.61M▲ 2.5%
144.25M▲ 313.4%
275.9M▲ 91.3%
267.53M▼ 3.0%
337.57M▲ 26.2%
551.48M▲ 63.4%
816.29M▲ 48.0%
Operating Margin %25.58%-45.65%-34.5%53.91%62.24%40.53%40.71%54.32%58.45%
Operating Income Growth %197.35%-185.59%2.48%313.36%91.26%-3.03%26.18%63.36%48.02%
EBITDA83.16M-66.94M-63.54M147.54M278.9M317.17M422.43M632.79M904.34M
EBITDA Margin %26.27%-44.08%-32.42%55.14%62.91%48.05%50.94%62.32%64.75%
EBITDA Growth %202.92%-180.49%5.08%332.19%89.03%13.72%33.19%49.8%42.91%
D&A (Non-Cash Add-back)2.16M2.39M4.07M3.28M3M49.64M84.86M81.31M88.05M
EBIT81M-69.33M-60.62M149.68M256.04M265.87M367.09M575.23M816.29M
Net Interest Income-21.98M-18.04M-11.63M-20.38M-7.53M-16.95M-18.76M-18.09M-18.13M
Interest Income000000000
Interest Expense21.98M18.04M11.63M20.38M7.53M16.95M18.76M18.09M18.13M
Other Income/Expense-19.39M-10.46M-4.64M-14.95M-27.38M-18.61M10.76M5.66M-349.42M
Pretax Income
61.61M▲ 0%
-79.79M▼ 229.5%
-72.25M▲ 9.5%
129.3M▲ 279.0%
248.52M▲ 92.2%
248.92M▲ 0.2%
348.33M▲ 39.9%
557.13M▲ 59.9%
466.88M▼ 16.2%
Pretax Margin %19.46%-52.54%-36.86%48.32%56.06%37.71%42.01%54.87%33.43%
Income Tax-1.36M537K-11K217K-154.19M46.79M66.73M113.04M149.99M
Effective Tax Rate %-2.21%-0.67%0.02%0.17%-62.04%18.8%19.16%20.29%32.13%
Net Income
62.97M▲ 0%
-80.33M▼ 227.6%
-72.24M▲ 10.1%
129.09M▲ 278.7%
402.71M▲ 212.0%
202.13M▼ 49.8%
281.59M▲ 39.3%
444.09M▲ 57.7%
316.89M▼ 28.6%
Net Margin %19.89%-52.9%-36.86%48.24%90.84%30.62%33.96%43.74%22.69%
Net Income Growth %161.12%-227.57%10.07%278.69%211.97%-49.81%39.31%57.71%-28.64%
Net Income (Continuing)62.97M-80.33M-72.24M129.09M402.71M202.13M281.59M444.09M316.89M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
0.45▲ 0%
-0.56▼ 224.4%
-0.50▲ 10.7%
0.91▲ 282.0%
2.74▲ 201.1%
1.44▼ 47.4%
2.10▲ 45.8%
3.43▲ 63.3%
2.56▼ 25.4%
EPS Growth %155.56%-224.44%10.71%282%201.1%-47.45%45.83%63.33%-25.36%
EPS (Basic)0.46-0.56-0.500.952.861.482.133.502.64
Diluted Shares Outstanding139.07M143.6M144.33M141.46M146.8M140.61M134.2M129.42M123.9M
Basic Shares Outstanding136.42M143.45M144.33M136.21M140.65M136.84M131.93M126.83M119.84M
Dividend Payout Ratio---------

HALO Balance Sheet

Halozyme Therapeutics, Inc. (HALO) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets510.37M427.85M543.44M554.76M926.29M739.01M746.42M1.09B825.21M
Cash & Short-Term Investments469.21M354.53M421.26M368.01M740.92M362.79M336M596.07M142.82M
Cash Only168.74M57.94M120.18M147.7M118.72M234.19M118.37M115.85M133.82M
Short-Term Investments300.47M296.59M301.08M220.31M622.2M128.6M217.63M480.22M9M
Accounts Receivable22.13M30M59.44M97.73M90.97M231.07M234.21M308.45M441.27M
Days Sales Outstanding25.5272.12110.7133.374.9127.77103.09110.89115.33
Inventory5.15M22.63M29.36M60.75M53.91M100.12M127.6M141.86M176.47M
Days Inventory Outstanding60.29814.73235.28511.28241.69262.34242.12324.8210.89
Other Current Assets0000045.02M48.61M38.95M64.64M
Total Non-Current Assets9.57M12.4M22.44M25.16M178.14M1.1B986.85M978.14M1.7B
Property, Plant & Equipment3.52M7.46M10.86M10.59M8.79M75.57M74.94M75.03M82.14M
Fixed Asset Turnover89.95x20.34x18.06x25.26x50.41x8.74x11.06x13.53x17.00x
Goodwill00000409.05M416.82M416.82M580.36M
Intangible Assets00000546.65M472.88M401.83M981.47M
Long-Term Investments000000000
Other Non-Current Assets6.05M4.93M11.58M14.57M13.91M26.8M17.82M80.6M56.15M
Total Assets
519.95M▲ 0%
440.25M▼ 15.3%
565.87M▲ 28.5%
579.92M▲ 2.5%
1.1B▲ 90.4%
1.84B▲ 66.7%
1.73B▼ 5.9%
2.06B▲ 19.1%
2.53B▲ 22.4%
Asset Turnover0.61x0.34x0.35x0.46x0.40x0.36x0.48x0.49x0.55x
Asset Growth %98.82%-15.33%28.54%2.48%90.44%66.74%-5.88%19.05%22.38%
Total Current Liabilities131.33M149.36M85.64M421.38M117.15M130.79M112.49M139.1M177.09M
Accounts Payable7.95M4.08M6.43M1.93M1.54M17.69M11.82M10.25M20.9M
Days Payables Outstanding93.12146.8951.5616.236.9146.3622.4223.4724.97
Short-Term Debt77.21M91.51M19.54M397.23M89.42M13.33M000
Deferred Revenue (Current)6.57M4.25M4.01M1.75M1.75M3.25M000
Other Current Liabilities00000-3.25M00156.19M
Current Ratio3.89x2.86x6.35x1.32x7.91x5.65x6.64x7.80x4.66x
Quick Ratio3.85x2.71x6.00x1.17x7.45x4.88x5.50x6.78x3.66x
Cash Conversion Cycle-7.31739.96294.42628.36309.68343.75322.79412.22301.24
Total Non-Current Liabilities180.25M42M388.47M7.49M790.33M1.54B1.54B1.56B2.3B
Long-Term Debt125.14M34.87M383.05M0787.25M1.49B1.5B1.51B0
Capital Lease Obligations000000000
Deferred Tax Liabilities0000000042.92M
Other Non-Current Liabilities814K2.12M4.18M3.47M544K45.91M37.72M54.76M2.26B
Total Liabilities311.58M191.36M474.11M428.88M907.48M1.67B1.65B1.7B2.48B
Total Debt202.35M126.38M402.59M397.23M876.67M1.51B1.5B1.51B0
Net Debt33.61M68.44M282.41M249.53M757.96M1.27B1.38B1.39B-133.82M
Debt / Equity0.97x0.51x4.39x2.63x4.45x8.87x17.89x4.14x-
Debt / EBITDA2.43x--2.69x3.14x4.75x3.55x2.38x-
Net Debt / EBITDA0.40x--1.69x2.72x4.01x3.27x2.20x-0.15x
Interest Coverage3.68x-3.84x-5.81x7.08x36.66x15.79x17.99x30.48x45.03x
Total Equity
208.37M▲ 0%
248.89M▲ 19.4%
91.77M▼ 63.1%
151.05M▲ 64.6%
196.95M▲ 30.4%
169.8M▼ 13.8%
83.81M▼ 50.6%
363.82M▲ 334.1%
48.81M▼ 86.6%
Equity Growth %741.5%19.45%-63.13%64.6%30.39%-13.79%-50.64%334.11%-86.58%
Book Value per Share1.501.730.641.071.341.210.622.810.39
Total Shareholders' Equity208.37M248.89M91.77M151.05M196.95M169.8M83.81M363.82M48.81M
Common Stock143K145K137K135K138K135K127K123K118K
Retained Earnings-522.37M-531.44M-603.68M-474.59M-58.91M143.22M90.55M359.87M54.79M
Treasury Stock000000000
Accumulated OCI-450K-277K240K22K-620K-922K-9.28M3.83M-18.09M
Minority Interest000000000

HALO Cash Flow Statement

Halozyme Therapeutics, Inc. (HALO) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations134.05M-49.5M-85.42M55.45M299.44M240.11M388.57M479.06M651.56M
Operating CF Margin %42.34%-32.6%-43.58%20.72%67.55%36.37%46.86%47.18%46.65%
Operating CF Growth %366.07%-136.93%-72.57%164.92%439.98%-19.81%61.83%23.29%36.01%
Net Income62.97M-80.33M-72.24M129.09M402.71M202.13M281.59M444.09M316.89M
Depreciation & Amortization2.16M2.39M6.55M17.42M6.64M57.48M84.86M88.66M88.05M
Stock-Based Compensation30.67M35.7M34.78M17.2M20.82M24.4M36.62M43.38M51.56M
Deferred Taxes-257K-3.08M000034.51M0634K
Other Non-Cash Items17.82M1.7M666K-41.1M-133.3M66.59M-10.33M39.2M346.68M
Working Capital Changes20.69M-5.87M-55.18M-67.16M2.57M-110.49M-38.67M-136.27M-152.26M
Change in Receivables-6.45M11.61M-29.44M-38.29M6.75M-83.94M-3.34M-74.25M-128.06M
Change in Inventory9.48M-17.48M-6.73M-31.39M7.37M-17.48M-26.88M-67.38M2.55M
Change in Payables15.63M-278.49M0000-12.55M00
Cash from Investing-163.73M2.49M-5.55M78.35M-406.29M-487M-96.91M-262.72M-545.81M
Capital Expenditures-1.35M-4.66M-4.04M-2.5M-1.46M-4.81M-15.29M-10.7M-6.97M
CapEx % of Revenue0.43%3.07%2.06%0.94%0.33%0.73%1.84%1.05%0.5%
Acquisitions00000-999.12M00-725.97M
Investments---------
Other Investing-162.38M7.16M-1.51M80.86M-404.83M516.92M0-252.03M-287.77M
Cash from Financing131.66M-63.8M153.22M-106.28M77.86M362.37M-407.99M-218.86M-85.17M
Debt Issued (Net)-15.99M-77.52M339.27M-19.56M415.81M624.55M-13.48M0235.37M
Equity Issued (Net)1000K0-1000K-1000K-1000K-1000K-1000K-1000K-1000K
Dividends Paid000000000
Share Repurchases00-200M-150.12M-350.06M-200M-402.38M-250M-342.37M
Other Financing12.78M13.72M13.95M63.39M12.11M-62.17M7.88M31.14M0
Net Change in Cash
101.98M▲ 0%
-110.8M▼ 208.7%
62.24M▲ 156.2%
27.52M▼ 55.8%
-28.98M▼ 205.3%
115.48M▲ 498.4%
-116.33M▼ 200.7%
-2.52M▲ 97.8%
20.57M▲ 916.3%
Free Cash Flow
132.7M▲ 0%
-54.16M▼ 140.8%
-89.46M▼ 65.2%
52.95M▲ 159.2%
297.98M▲ 462.8%
235.3M▼ 21.0%
373.28M▲ 58.6%
468.37M▲ 25.5%
644.59M▲ 37.6%
FCF Margin %41.91%-35.67%-45.65%19.79%67.22%35.65%45.01%46.13%46.15%
FCF Growth %347.95%-140.82%-65.17%159.19%462.76%-21.04%58.64%25.47%37.62%
FCF per Share0.95-0.38-0.620.372.031.672.783.625.20
FCF Conversion (FCF/Net Income)2.13x0.62x1.18x0.43x0.74x1.19x1.38x1.08x2.06x
Interest Paid20.3M16.89M9.03M6.53M3.3M6.11M11.41M10.56M0
Taxes Paid3.02M220K000031.76M00

HALO Key Ratios

Halozyme Therapeutics, Inc. (HALO) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-1958.98%71.6%-35.14%-42.41%106.33%231.44%110.23%222.07%198.42%153.59%
Return on Invested Capital (ROIC)-74.78%33.81%-18.59%-14.67%27.93%30.53%16.74%17.42%25.7%73.37%
Gross Margin77.36%90.16%93.33%76.76%83.79%81.64%78.9%76.8%84.3%78.13%
Net Margin-70.23%19.89%-52.9%-36.86%48.24%90.84%30.62%33.96%43.74%22.69%
Debt / Equity-0.97x0.51x4.39x2.63x4.45x8.87x17.89x4.14x-
Interest Coverage-4.17x3.68x-3.84x-5.81x7.08x36.66x15.79x17.99x30.48x45.03x
FCF Conversion0.49x2.13x0.62x1.18x0.43x0.74x1.19x1.38x1.08x2.06x
Revenue Growth8.61%115.84%-52.04%29.06%36.53%65.67%48.91%25.62%22.44%37.55%

HALO SEC Filings & Documents

Halozyme Therapeutics, Inc. (HALO) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 12, 2026·SEC

Material company update

Feb 17, 2026·SEC

Material company update

Jan 28, 2026·SEC

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HALO Frequently Asked Questions

Halozyme Therapeutics, Inc. (HALO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Halozyme Therapeutics, Inc. (HALO) reported $1.40B in revenue for fiscal year 2025. This represents a 5657631% increase from $0.0M in 2001.

Halozyme Therapeutics, Inc. (HALO) grew revenue by 37.6% over the past year. This is strong growth.

Yes, Halozyme Therapeutics, Inc. (HALO) is profitable, generating $316.9M in net income for fiscal year 2025 (22.7% net margin).

Dividend & Returns

Halozyme Therapeutics, Inc. (HALO) has a return on equity (ROE) of 153.6%. This is excellent, indicating efficient use of shareholder capital.

Halozyme Therapeutics, Inc. (HALO) generated $644.6M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

Explore More HALO

Halozyme Therapeutics, Inc. (HALO) financial analysis — history, returns, DCA and operating performance tools

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