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Humacyte, Inc. (HUMA) 10-Year Financial Performance & Capital Metrics

HUMA • • Industrial / General
HealthcareBiotechnologyPlatform & Technology CompaniesAntibody Discovery Platforms
AboutHumacyte, Inc. engages in the development and manufacture of off-the-shelf, implantable, and bioengineered human tissues for the treatment of diseases and conditions across a range of anatomic locations in multiple therapeutic areas. The company using its proprietary and scientific technology platform to engineer and manufacture human acellular vessels (HAVs). Its investigational HAVs are designed to be easily implanted into any patient without inducing a foreign body response or leading to immune rejection. The company is developing a portfolio of HAVs, which would target the vascular repair, reconstruction, and replacement market, including vascular trauma; arteriovenous access for hemodialysis; peripheral arterial disease; and coronary artery bypass grafting, as well as developing its HAVs for pediatric heart surgery and cellular therapy delivery, including pancreatic islet cell transplantation to treat Type 1 diabetes. The company was founded in 2004 and is headquartered in Durham, North Carolina.Show more
  • Revenue $0
  • EBITDA -$107M -16.1%
  • Net Income -$149M -34.2%
  • EPS (Diluted) -1.26 -17.8%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -
  • ROIC -
  • Debt/Equity -
  • Interest Coverage -12.33 +18.7%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Weak momentum: RS Rating 14 (bottom 14%)
  • ✗Shares diluted 14.6% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM75.82%

EPS CAGR

10Y-
5Y-
3Y-
TTM82.84%

ROCE

10Y Avg-59.04%
5Y Avg-59.99%
3Y Avg-68.39%
Latest-100.48%

Peer Comparison

Antibody Discovery Platforms
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Sector-Specific
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NAGENiagen Bioscience Inc503.58M6.3157.3619.18%16.38%28.91%2.37%0.06
BTXBlackRock Technology and Private Equity Term Trust808.8M6.9340.76-81.13%87.75%1.87%34.27%
HALOHalozyme Therapeutics, Inc.8.45B71.8220.9422.44%47.91%118.17%5.55%4.14
RPRXRoyalty Pharma plc16.97B39.7220.80-3.86%32.55%7.95%16.32%0.74
REGNRegeneron Pharmaceuticals, Inc.76.63B741.9219.358.27%32.13%14.79%4.78%0.09
GMABGenmab A/S20.85B33.852.7930.67%46.8%114.25%36.37%0.03
DNAGinkgo Bioworks Holdings, Inc.464.86M9.58-0.91-9.71%-188%-60.66%0.65
PRMEPrime Medicine, Inc.720.24M3.99-2.42-33.02%-121.95%0.27

Profit & Loss

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+6.19M1.49M1.26M1.56M00
Revenue Growth %--0.76%-0.15%0.24%-1%-
Cost of Goods Sold+75.6M54.08M61.34M8.26M76.55M7.19M
COGS % of Revenue12.22%36.27%48.57%5.27%--
Gross Profit+-69.42M-52.59M-60.08M-6.69M-76.55M-7.19M
Gross Margin %-11.22%-35.27%-47.57%-4.27%--
Gross Profit Growth %-0.24%-0.14%0.89%-10.44%0.91%
Operating Expenses+16.27M12.01M21.13M77.89M23.5M107.21M
OpEx % of Revenue2.63%8.06%16.73%49.77%--
Selling, General & Admin16.27M12.01M21.13M22.88M20.39M25.8M
SG&A % of Revenue2.63%8.06%16.73%14.62%--
Research & Development75.6M54.08M61.34M63.26M76.55M88.6M
R&D % of Revenue12.22%36.27%48.57%40.42%--
Other Operating Expenses-75.6M-54.08M-61.34M-8.26M-73.44M-7.19M
Operating Income+-85.69M-64.6M-81.21M-84.58M-100.05M-114.4M
Operating Margin %-13.85%-43.33%-64.3%-54.04%--
Operating Income Growth %-0.25%-0.26%-0.04%-0.18%-0.14%
EBITDA+-78.94M-56.25M-72.97M-76.37M-92.33M-107.21M
EBITDA Margin %-12.76%-37.73%-57.77%-48.8%--
EBITDA Growth %-0.29%-0.3%-0.05%-0.21%-0.16%
D&A (Non-Cash Add-back)6.75M8.35M8.24M8.21M7.72M7.19M
EBIT-85.69M-64.6M-81.21M-84.58M-104.18M-139.42M
Net Interest Income+-2.03M-1.92M-4.33M-3.57M-1.13M-5.17M
Interest Income269K278K16K2.63M5.47M4.1M
Interest Expense2.3M2.2M4.35M6.2M6.6M9.28M
Other Income/Expense269K-1.92M54.73M72.61M-10.73M-34.3M
Pretax Income+-85.42M-66.52M-26.48M-11.96M-110.78M-148.7M
Pretax Margin %-13.81%-44.62%-20.96%-7.65%--
Income Tax+000000
Effective Tax Rate %1%1%1%1%1%1%
Net Income+-85.42M-66.52M-26.48M-11.96M-110.78M-148.7M
Net Margin %-13.81%-44.62%-20.96%-7.65%--
Net Income Growth %-0.22%0.6%0.55%-8.26%-0.34%
Net Income (Continuing)-85.42M-66.52M-26.48M-11.96M-110.78M-148.7M
Discontinued Operations000000
Minority Interest000000
EPS (Diluted)+-4.25-5.52-0.66-0.12-1.07-1.26
EPS Growth %--0.3%0.88%0.82%-7.92%-0.18%
EPS (Basic)-4.25-5.52-0.66-0.12-1.07-1.26
Diluted Shares Outstanding20.12M12.45M39.97M103.05M103.42M118.48M
Basic Shares Outstanding20.12M12.45M39.97M103.05M103.42M118.48M
Dividend Payout Ratio------

Balance Sheet

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+94.95M41.45M229.34M154.21M83.28M47.86M
Cash & Short-Term Investments93.71M39.93M225.5M151.88M80.45M44.94M
Cash Only93.71M39.93M217.5M149.77M80.45M44.94M
Short-Term Investments008M2.11M00
Accounts Receivable601K113K176K31K00
Days Sales Outstanding35.4627.6650.867.23--
Inventory000000
Days Inventory Outstanding------
Other Current Assets0002.3M2.83M2.92M
Total Non-Current Assets+73.74M65.24M57.19M50.09M44.95M90.01M
Property, Plant & Equipment73.74M65.24M57.19M50.09M44.1M38.55M
Fixed Asset Turnover0.08x0.02x0.02x0.03x--
Goodwill000000
Intangible Assets000000
Long-Term Investments000000
Other Non-Current Assets0000841K51.46M
Total Assets+168.69M106.69M286.53M204.3M128.22M137.87M
Asset Turnover0.04x0.01x0.00x0.01x--
Asset Growth %--0.37%1.69%-0.29%-0.37%0.08%
Total Current Liabilities+10.84M11.23M11.05M19.58M18.44M19.95M
Accounts Payable3.27M2.27M2.09M1.59M6.49M4.49M
Days Payables Outstanding15.815.3512.4670.5230.95227.93
Short-Term Debt1.5M2.45M08.57M00
Deferred Revenue (Current)000000
Other Current Liabilities-1.5M1.15M4.12M4.23M5.29M7.37M
Current Ratio8.76x3.69x20.75x7.88x4.52x2.40x
Quick Ratio8.76x3.69x20.75x7.88x4.52x2.40x
Cash Conversion Cycle------
Total Non-Current Liabilities+25.65M24.78M153.31M67.79M96.23M170.59M
Long-Term Debt0822K27.36M20.34M38.6M0
Capital Lease Obligations25.65M23.82M21.79M18.85M16.29M13.62M
Deferred Tax Liabilities000000
Other Non-Current Liabilities0144K104.16M28.61M41.34M156.97M
Total Liabilities36.49M36.02M164.36M87.37M114.68M190.54M
Total Debt+28.72M28.86M51.18M50.07M57.45M16.54M
Net Debt-65M-11.07M-166.32M-99.71M-23M-28.4M
Debt / Equity0.22x0.41x0.42x0.43x4.24x-
Debt / EBITDA------
Net Debt / EBITDA------
Interest Coverage-37.29x-29.34x-18.68x-13.64x-15.16x-12.33x
Total Equity+132.2M70.67M122.17M116.93M13.55M-52.67M
Equity Growth %--0.47%0.73%-0.04%-0.88%-4.89%
Book Value per Share6.575.683.061.130.13-0.44
Total Shareholders' Equity132.2M70.67M122.17M116.93M13.55M-52.67M
Common Stock21K1K10K10K10K13K
Retained Earnings-321.57M-388.1M-414.57M-426.54M-537.31M-686.01M
Treasury Stock000000
Accumulated OCI000000
Minority Interest000000

Cash Flow

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-71.79M-55.57M-81.19M-71.13M-73.31M-98.12M
Operating CF Margin %-11.6%-37.27%-64.28%-45.45%--
Operating CF Growth %-0.23%-0.46%0.12%-0.03%-0.34%
Net Income-85.42M-66.52M-26.48M-11.96M-110.78M-148.7M
Depreciation & Amortization6.75M8.43M8.24M8.21M7.72M7.19M
Stock-Based Compensation4.46M010.15M6.18M06.14M
Deferred Taxes-4.27M00000
Other Non-Cash Items6.25M4.89M-72.54M-74.59M23.18M36.94M
Working Capital Changes453K-2.37M-557K1.03M6.57M311K
Change in Receivables-185K488K-63K145K31K0
Change in Inventory-2.43M00000
Change in Payables2.43M-889K-197K-509K4.81M-1.96M
Cash from Investing+-8.13M-268K-8.22M4.84M-173K-1.57M
Capital Expenditures-8.13M-318K-220K-1.05M-2.28M-1.57M
CapEx % of Revenue1.31%0.21%0.17%0.67%--
Acquisitions------
Investments------
Other Investing000000
Cash from Financing+-74K2.05M266.98M-1.45M4.51M114.18M
Debt Issued (Net)------
Equity Issued (Net)------
Dividends Paid000000
Share Repurchases------
Other Financing1.22M0239.05M535K-1.76M27.71M
Net Change in Cash------
Free Cash Flow+-79.91M-55.89M-81.41M-72.18M-75.58M-99.69M
FCF Margin %-12.92%-37.48%-64.46%-46.12%--
FCF Growth %-0.3%-0.46%0.11%-0.05%-0.32%
FCF per Share-3.97-4.49-2.04-0.70-0.73-0.84
FCF Conversion (FCF/Net Income)0.84x0.84x3.07x5.94x0.66x0.66x
Interest Paid001.12M2.67M00
Taxes Paid000000

Key Ratios

Metric201920202021202220232024
Return on Equity (ROE)-64.62%-65.58%-27.46%-10.01%-169.81%-
Return on Invested Capital (ROIC)--76.41%-788.22%--1930.66%-
Gross Margin-1121.97%-3526.96%-4756.77%-427.48%--
Net Margin-1380.67%-4461.7%-2096.36%-764.54%--
Debt / Equity0.22x0.41x0.42x0.43x4.24x-
Interest Coverage-37.29x-29.34x-18.68x-13.64x-15.16x-12.33x
FCF Conversion0.84x0.84x3.07x5.94x0.66x0.66x
Revenue Growth--75.9%-15.29%23.91%-100%-

Frequently Asked Questions

Growth & Financials

Humacyte, Inc. (HUMA) reported $8.8M in revenue for fiscal year 2024. This represents a 42% increase from $6.2M in 2019.

Humacyte, Inc. (HUMA) grew revenue by 0.0% over the past year. Growth has been modest.

Humacyte, Inc. (HUMA) reported a net loss of $37.0M for fiscal year 2024.

Dividend & Returns

Humacyte, Inc. (HUMA) had negative free cash flow of $106.4M in fiscal year 2024, likely due to heavy capital investments.

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