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ORKAOruka Therapeutics, Inc.
$90.60$3.4B
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ORKA logoOruka Therapeutics, Inc.(ORKA)Earnings, Financials & Key Ratios

ORKA•NASDAQ
$90.60
Price updated Jun 27, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutOruka Therapeutics, Inc. is a biotechnology company, which focuses on developing novel monoclonal antibody therapeutics for PsO and other I&I indications. Its pipeline includes ORKA-001 and ORKA-002. The company is headquartered in Menlo Park, CA.Show more
  • Revenue$0
  • EBITDA-$122M-38.4%
  • Net Income-$105M-25.9%
  • EPS (Diluted)-2.31+53.7%
  • ROE-24.69%+37.5%

ORKA Price & Volume

Oruka Therapeutics, Inc. (ORKA) stock price & volume — 10-year historical chart

Loading chart...

Clinical Development Costs Outpace Cash Runway Sustainability

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial Position:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical development funding gap
"Oruka Therapeutics faces a precarious financial outlook as it advances its proprietary antibody platform, characterized by a lack of commercial revenue and widening quarterly operating losses that reached $36.4 million in 2026Q1. The company's reliance on external financing to fund intensive R&D, which totaled $29.1 million in the most recent quarter, creates significant exposure to dilutive capital raises. Investors should monitor the company's ability to achieve clinical milestones, as the current cash position of $49.5 million appears insufficient to sustain long-term operations without further liquidity events."

Verdict Logic

the company's rapid depletion of liquidity, evidenced by a cash balance of only $49.5 million against quarterly operating losses of $36.4 million, suggests a high probability of near-term dilutive financing.

ORKA Growth Metrics

Oruka Therapeutics, Inc. (ORKA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-10.45%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM54.48%

Return on Capital

10 Years-56.44%
5 Years-33.24%
3 Years-30.35%
Last Year-28.51%

ORKA Recent Earnings

Oruka Therapeutics, Inc. (ORKA) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (75%)
Q2 2026Latest
May 13, 2026
Metric
Actual
Est
EPS
$0.48+12.2%
$0.55
Rev
—
—
Q2 2026
Mar 12, 2026
Metric
Actual
Est
EPS
$0.45+26.2%
$0.61
Rev
—
—
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.55+1.8%
$0.56
Rev
—
—
Q3 2025
Aug 11, 2025
Metric
Actual
Est
EPS
$0.46+4.2%
$0.48
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 13, 2026
$0.48vs $0.55+12.2%
—
Q2 2026Mar 12, 2026
$0.45vs $0.61+26.2%
—
Q4 2025Nov 12, 2025
$0.55vs $0.56+1.8%
—
Q3 2025Aug 11, 2025
$0.46vs $0.48+4.2%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Oruka Therapeutics, Inc. (ORKA)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ORKA logoORKAOruka Therapeutics, Inc.Current
$90.60$3.39B-39.22——-24.69%—
REGN logoREGNRegeneron Pharmaceuticals, Inc.
$632.90$65.76B15.260.99%29.65%14.32%—
SANA logoSANASana Biotechnology, Inc.
$3.42$951.76M-3.56——-161.87%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$27.00$3.38B-207.6991.34%-0.57%-1.41%—
DAWN logoDAWNDay One Biopharmaceuticals, Inc.
$21.53$2.22B-20.7020.6%-67.85%-23.43%—
IMVT logoIMVTImmunovant, Inc.
$38.85$7.98B-14.03——-68.16%—

Compare ORKA vs Peers

Oruka Therapeutics, Inc. (ORKA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs REGN

Most directly comparable listed peer for ORKA.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ORKA against a more recognizable public peer.

Peer Set

Compare Top 5

vs REGN, SANA, ARQT, DAWN

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ORKA Frequently Asked Questions

Oruka Therapeutics, Inc. (ORKA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is ORKA profitable?

Oruka Therapeutics, Inc. (ORKA) reported a net loss of $116.3M for fiscal year 2025.

Dividend & Returns
What is ORKA's return on equity?

Oruka Therapeutics, Inc. (ORKA) has a return on equity (ROE) of -24.7%. Negative ROE indicates the company is unprofitable.

What is Oruka Therapeutics, Inc.'s free cash flow?

Oruka Therapeutics, Inc. (ORKA) had negative free cash flow of $91.2M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ORKA back in 2005?

Total return calculator · dividends reinvested · 21+ years of data

See returns →