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Q32 Bio Inc. (QTTB) 10-Year Financial Performance & Capital Metrics

QTTB • • Industrial / General
HealthcareBiotechnologyAutoimmune & Inflammatory DiseasesDermatology & Autoimmune
AboutQ32 Bio Inc., a clinical-stage biotechnology company, develops biologic therapeutics to restore healthy immune balance in patients with autoimmune and inflammatory diseases driven by pathological immune dysfunction in the United States. Its lead product candidate is ADX-097, a humanized anti-C3d monoclonal antibody fusion protein to restore complement regulation, which has completed Phase I clinical trial for the treatment of renal and other complement-mediated diseases of high unmet need, including lupus nephritis, immunoglobulin A nephropathy, complement component 3 glomerulopathy, and anti-neutrophil cytoplasmic antibody-associated vasculitis. The company is also developing Bempikibart (ADX-914), a fully human anti–interleukin-7 receptor alpha antagonist monoclonal antibody designed to re-regulate adaptive immune function by blocking signaling mediated by interleukin-7 and thymic stromal lymphopoietin that is Phase II clinical trial for the treatment of atopic dermatitis and alopecia areata. Q32 Bio Inc. was formerly known as AdMIRx Inc. and changed its name to Q32 Bio Inc. in April 2020. The company was founded in 2017 and is based in Waltham, Massachusetts.Show more
  • Revenue $0 +100.0%
  • EBITDA -$66M -37.4%
  • Net Income -$48M +11.2%
  • EPS (Diluted) -6.58 +60.6%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -841.11%
  • ROIC -
  • Debt/Equity 3.33
  • Interest Coverage -220.34
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 94 (top 6%)
  • ✓High quality earnings: Operating CF exceeds net income

✗Weaknesses

  • ✗High debt to equity ratio of 3.3x
  • ✗Weak Piotroski F-Score: 3/9
  • ✗Shares diluted 100.0% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM100%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM30.54%

EPS CAGR

10Y-
5Y-
3Y-
TTM55.86%

ROCE

10Y Avg-84.46%
5Y Avg-103.05%
3Y Avg-140.96%
Latest-121.49%

Peer Comparison

Dermatology & Autoimmune
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
AUPHAurinia Pharmaceuticals Inc.1.96B14.87378.3733.97%29.28%21.28%2.25%0.21
ARGXargenx SE50.33B813.2463.6378.6%23.34%15.14%0.01
INVAInnoviva, Inc.1.48B19.7654.8915.54%32.78%12.61%12.75%0.65
GLPGGalapagos N.V.2.24B34.0330.3814.99%-151.94%-15.16%0.00
PTGXProtagonist Therapeutics, Inc.5.3B84.7520.046.24%21.94%7.11%3.45%0.02
ALMSAlumis Inc. Common Stock2.84B24.17-2.33-11.08%-63.71%0.12
PHATPhathom Pharmaceuticals, Inc.1.17B14.98-2.8380.01%-186.53%
ORKAOruka Therapeutics, Inc.1.57B32.50-6.51-22.44%0.00

Profit & Loss

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+005.32M1.67M2.7M33.97M6.65M-6.65M0
Revenue Growth %----0.69%0.62%11.57%-0.8%-2%1%
Cost of Goods Sold+239.8K684.21K0009.54M00487K
COGS % of Revenue-----0.28%---
Gross Profit+-239.8K-684.21K5.32M1.67M2.7M24.43M6.65M-6.65M-487K
Gross Margin %--1%1%1%0.72%1%1%-
Gross Profit Growth %--1.85%8.78%-0.69%0.62%8.04%-0.73%-2%0.93%
Operating Expenses+9.76M28.97M63.96M105.29M124.06M120.38M45.88M41.6M65.61M
OpEx % of Revenue--12.02%63.2%45.91%3.54%6.9%-6.26%-
Selling, General & Admin4.07M7.6M16.01M15.89M23.67M27.29M10.06M9.88M17.47M
SG&A % of Revenue--3.01%9.54%8.76%0.8%1.51%-1.48%-
Research & Development5.69M21.38M47.95M89.4M100.39M93.08M35.81M31.73M48.14M
R&D % of Revenue--9.01%53.66%37.15%2.74%5.38%-4.77%-
Other Operating Expenses000000000
Operating Income+-10M-29.66M-59.93M-109.94M-130.26M-95.95M-39.23M-48.26M-66.1M
Operating Margin %---11.26%-65.99%-48.21%-2.82%-5.9%7.26%-
Operating Income Growth %--1.97%-1.02%-0.83%-0.18%0.26%0.59%-0.23%-0.37%
EBITDA+-9.76M-28.97M-58.64M-103.63M-121.36M-86.41M-38.85M-47.76M-65.61M
EBITDA Margin %---11.02%-62.2%-44.91%-2.54%-5.84%7.18%-
EBITDA Growth %--1.97%-1.02%-0.77%-0.17%0.29%0.55%-0.23%-0.37%
D&A (Non-Cash Add-back)239.8K684.21K1.29M6.32M8.9M9.54M370K499K487K
EBIT-8.05M-29.99M-55.58M-103.92M-128.69M-95.76M-39.23M-48.26M-45.79M
Net Interest Income+0006.03M1.57M0003.6M
Interest Income24.2K542.63K4.35M6.03M1.57M0003.9M
Interest Expense00000000300K
Other Income/Expense1.95M-333.37K4.35M6.03M1.57M185K-3.52M-5.17M18.39M
Pretax Income+-8.05M-29.99M-55.58M-103.92M-128.69M-95.76M-42.75M-53.42M-47.71M
Pretax Margin %---10.44%-62.37%-47.63%-2.82%-6.43%8.03%-
Income Tax+2-4000062K318K21K
Effective Tax Rate %1%1%1%1%1%1%1%1.01%1%
Net Income+-8.05M-29.99M-55.58M-103.92M-128.69M-95.76M-42.81M-53.74M-47.73M
Net Margin %---10.44%-62.37%-47.63%-2.82%-6.44%8.08%-
Net Income Growth %--2.73%-0.85%-0.87%-0.24%0.26%0.55%-0.26%0.11%
Net Income (Continuing)-8.05M-29.99M-55.58M-103.92M-128.69M-95.76M-42.81M-53.74M-47.73M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)+-3.87-14.42-35.04-44.41-50.46-12.23-13.42-16.70-6.58
EPS Growth %--2.73%-1.43%-0.27%-0.14%0.76%-0.1%-0.24%0.61%
EPS (Basic)-3.87-14.42-35.04-44.41-50.46-12.23-13.42-16.70-5.12
Diluted Shares Outstanding2.08M2.08M1.59M2.34M2.55M3.07M3.19M3.22M12.2M
Basic Shares Outstanding2.08M2.08M1.59M2.34M2.55M3.07M3.19M3.22M12.2M
Dividend Payout Ratio---------

Balance Sheet

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+11.99M131.6M221.69M266.58M219.56M191.91M46.85M28.72M81.88M
Cash & Short-Term Investments11.39M129.66M214.74M262.39M217.43M155.87M43.89M25.62M77.97M
Cash Only11.39M51.57M38.22M53.77M217.43M108.38M43.89M25.62M77.97M
Short-Term Investments078.08M176.52M208.61M047.49M000
Accounts Receivable113.26K0800K400K400K01.06M755K555K
Days Sales Outstanding--54.8787.6454.03-58.39-41.43-
Inventory0000001.75M00
Days Inventory Outstanding---------
Other Current Assets481.79K1.94M6.15M3.79M1.73M36.04M146K83K396K
Total Non-Current Assets+2.23M5.93M37.41M43.99M44.17M19.81M14.92M18.34M10.46M
Property, Plant & Equipment1.96M3.15M35.64M42.72M42.9M17.86M9.17M8.08M7.09M
Fixed Asset Turnover--0.15x0.04x0.06x1.90x0.73x-0.82x-
Goodwill000000000
Intangible Assets000000000
Long-Term Investments276K1.77M1.77M1.27M1.27M1.95M25.81M02.6M
Other Non-Current Assets01M0000-20.06M10.26M763K
Total Assets+14.22M137.53M259.09M310.57M263.74M211.72M61.77M47.06M92.33M
Asset Turnover--0.02x0.01x0.01x0.16x0.11x-0.14x-
Asset Growth %-8.67%0.88%0.2%-0.15%-0.2%-0.71%-0.24%0.96%
Total Current Liabilities+6.38M8.86M22.52M12.37M22.66M17.23M57.87M14.11M16.46M
Accounts Payable893.67K2.54M15.73M2.61M4.72M2.37M1.44M3.47M2.99M
Days Payables Outstanding1.36K1.35K---90.49--2.24K
Short-Term Debt00002.5M246K32.4M878K3.1M
Deferred Revenue (Current)01000K770K809K1000K1000K1000K00
Other Current Liabilities5.48M2.98M6.02M8.96M9.8M11.41M2.79M3M5.68M
Current Ratio1.88x14.85x9.84x21.54x9.69x11.14x0.81x2.04x4.97x
Quick Ratio1.88x14.85x9.84x21.54x9.69x11.14x0.78x2.04x4.97x
Cash Conversion Cycle---------
Total Non-Current Liabilities+340.63K30.36M40.22M39.69M45.08M24.84M134.62M215.87M70.19M
Long-Term Debt0000005.07M43.18M9.56M
Capital Lease Obligations000012.94M23.69M6.79M6.25M5.64M
Deferred Tax Liabilities000000000
Other Non-Current Liabilities340.63K290.92K9.47M9.54M00111.44M166.44M55M
Total Liabilities6.72M39.22M62.74M52.06M67.74M42.07M192.49M229.98M86.66M
Total Debt+000015.44M23.93M44.73M50.84M18.9M
Net Debt-11.39M-51.57M-38.22M-53.77M-201.99M-84.45M838K25.22M-59.06M
Debt / Equity----0.08x0.14x--3.33x
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage---------220.34x
Total Equity+7.5M98.31M196.35M258.51M196M169.65M-130.71M-182.92M5.67M
Equity Growth %-12.11%1%0.32%-0.24%-0.13%-1.77%-0.4%1.03%
Book Value per Share3.6147.28123.79110.4876.8455.24-40.99-56.830.47
Total Shareholders' Equity7.5M98.31M196.35M258.51M196M169.65M-130.71M-182.92M5.67M
Common Stock1.12K1.39K3K4K5K6K1K1K2K
Retained Earnings-10.19M-40.18M-95.76M-199.67M-328.37M-424.13M-133.34M-187.08M-234.81M
Treasury Stock000000715.93M00
Accumulated OCI-1.12K-73.31K-77K183K0-7K-404K00
Minority Interest000000000

Cash Flow

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-8.48M6.48M-42.56M-91.36M-94.33M-109.75M-10.96M-18.68M-67.72M
Operating CF Margin %---8%-54.84%-34.91%-3.23%-1.65%2.81%-
Operating CF Growth %-1.76%-7.57%-1.15%-0.03%-0.16%0.9%-0.7%-2.63%
Net Income-8.05M-29.99M-55.58M-103.92M-128.69M-95.76M-42.81M-53.74M-47.73M
Depreciation & Amortization239.8K684.21K1.29M6.32M8.9M9.54M370K499K487K
Stock-Based Compensation0000001.24M04.39M
Deferred Taxes0000002.42M00
Other Non-Cash Items-1.64M715.96K-644K5.78M13.94M18.27M876K8.25M-15.22M
Working Capital Changes928.48K34.72M10.56M463K11.52M-41.8M26.94M26.32M-9.64M
Change in Receivables000000000
Change in Inventory000000000
Change in Payables517.97K1.72M4.38M-4.45M2.46M-2.49M-1.24M2.03M-1.04M
Cash from Investing+-2.27M-81.53M-121.79M-51.8M204.9M-50.79M-2.47M-5K19.93M
Capital Expenditures-1.99M-1.96M-24.94M-21.83M-3.73M-2.4M-2.48M-5K-75K
CapEx % of Revenue--4.69%13.11%1.38%0.07%0.37%-0%-
Acquisitions---------
Investments---------
Other Investing000000-37.98M00
Cash from Financing+378.31K115.23M150.99M158.21M53.09M52.17M30.07M406K95.14M
Debt Issued (Net)---------
Equity Issued (Net)---------
Dividends Paid000000000
Share Repurchases---------
Other Financing0000000046.14M
Net Change in Cash---------
Free Cash Flow+-10.47M4.52M-67.5M-113.19M-98.06M-112.15M-13.44M-18.68M-67.79M
FCF Margin %---12.68%-67.94%-36.29%-3.3%-2.02%2.81%-
FCF Growth %-1.43%-15.93%-0.68%0.13%-0.14%0.88%-0.39%-2.63%
FCF per Share-5.042.17-42.55-48.37-38.45-36.51-4.22-5.80-5.56
FCF Conversion (FCF/Net Income)1.05x-0.22x0.77x0.88x0.73x1.15x0.26x0.35x1.42x
Interest Paid00000000856K
Taxes Paid000000000

Key Ratios

Metric201620172018201920202021202220232024
Return on Equity (ROE)-107.29%-56.69%-37.72%-45.69%-56.63%-52.38%-219.88%--841.11%
Return on Invested Capital (ROIC)--103.84%-43.88%-45.45%-98.32%-181.7%---
Gross Margin--100%100%100%71.91%100%100%-
Net Margin---1044.29%-6237.45%-4762.92%-281.9%-643.65%808.04%-
Debt / Equity----0.08x0.14x--3.33x
Interest Coverage---------220.34x
FCF Conversion1.05x-0.22x0.77x0.88x0.73x1.15x0.26x0.35x1.42x
Revenue Growth----68.7%62.18%1157.25%-80.42%-200%100%

Frequently Asked Questions

Growth & Financials

Q32 Bio Inc. (QTTB) grew revenue by 100.0% over the past year. This is strong growth.

Q32 Bio Inc. (QTTB) reported a net loss of $42.1M for fiscal year 2024.

Dividend & Returns

Q32 Bio Inc. (QTTB) has a return on equity (ROE) of -841.1%. Negative ROE indicates the company is unprofitable.

Q32 Bio Inc. (QTTB) had negative free cash flow of $38.8M in fiscal year 2024, likely due to heavy capital investments.

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