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Avidity Biosciences, Inc. (RNA) 10-Year Financial Performance & Capital Metrics

RNA • • Industrial / General
HealthcareBiotechnologyRare Genetic DiseasesGene Therapy & Rare Diseases
AboutAvidity Biosciences, Inc., a biopharmaceutical company, engages in the development of oligonucleotide-based therapies. It develops antibody oligonucleotide conjugates (AOC) that are designed to treat a range of serious diseases. The company's lead product candidate AOC 1001 is used for the treatment of myotonic dystrophy type 1, a rare monogenic muscle disease; AOC 1044 for the treatment of Duchenne Muscular Dystrophy; and AOC 1020 designed to treat facioscapulohumeral muscular dystrophy which are in preclinical stage. It also offers Lumizyme therapy for Pompe diseases. Avidity Biosciences, Inc. was incorporated in 2012 and is headquartered in San Diego, California.Show more
  • Revenue $11M +14.0%
  • EBITDA -$376M -61.1%
  • Net Income -$322M -51.9%
  • EPS (Diluted) -2.89 +0.7%
  • Gross Margin 100% +28.2%
  • EBITDA Margin -3451.96% -41.3%
  • Operating Margin -3477.43% -41.1%
  • Net Margin -2957.71% -33.2%
  • ROE -33.47% +14.9%
  • ROIC -36.97% +40.0%
  • Debt/Equity 0.00 -75.7%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 92 (top 8%)
  • ✓Strong 5Y sales CAGR of 36.3%
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 52.8% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y36.27%
3Y5.33%
TTM106.27%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-96.01%

EPS CAGR

10Y-
5Y-
3Y-
TTM-44.64%

ROCE

10Y Avg-35.09%
5Y Avg-34.04%
3Y Avg-38.5%
Latest-37.63%

Peer Comparison

Gene Therapy & Rare Diseases
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
KRYSKrystal Biotech, Inc.8.18B282.0194.00473.02%53.3%17.48%1.46%0.01
BMRNBioMarin Pharmaceutical Inc.10.58B55.0724.9217.97%16.82%8.59%4.49%0.11
SRPTSarepta Therapeutics, Inc.2.23B21.319.1152.97%-11.25%-20.57%0.88
RAREUltragenyx Pharmaceutical Inc.2.27B23.50-3.7429.01%-91.95%-35.88%0.15
DYNDyne Therapeutics, Inc.2.7B16.42-4.87-61.26%0.04
TVTXTravere Therapeutics, Inc.2.54B28.40-6.9660.55%-20.32%-120.36%6.80
BEAMBeam Therapeutics Inc.3.25B32.05-7.00-83.18%-7.44%-42.92%0.22
SLNOSoleno Therapeutics, Inc.2.25B41.95-9.58-79.5%-15.85%0.22

Profit & Loss

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+379K2.32M6.79M9.33M9.22M9.56M10.9M
Revenue Growth %-5.12%1.93%0.37%-0.01%0.04%0.14%
Cost of Goods Sold+8.44M037.6M101.18M1.39M2.1M0
COGS % of Revenue22.26%-5.54%10.85%0.15%0.22%-
Gross Profit+-8.06M2.32M-30.82M-91.86M7.84M7.46M10.9M
Gross Margin %-21.26%1%-4.54%-9.85%0.85%0.78%1%
Gross Profit Growth %-1.29%-14.29%-1.98%1.09%-0.05%0.46%
Operating Expenses+10.88M19.65M13.46M26.2M186.75M243.06M389.83M
OpEx % of Revenue28.7%8.47%1.98%2.81%20.25%25.42%35.77%
Selling, General & Admin2.44M5.11M13.46M26.2M37.73M54.19M86.24M
SG&A % of Revenue6.44%2.2%1.98%2.81%4.09%5.67%7.91%
Research & Development8.44M14.54M37.6M101.18M150.4M190.97M303.59M
R&D % of Revenue22.26%6.27%5.54%10.85%16.31%19.98%27.86%
Other Operating Expenses00-37.6M-101.18M-1.39M-2.1M0
Operating Income+-10.5M-17.33M-44.28M-118.05M-178.91M-235.6M-378.94M
Operating Margin %-27.7%-7.47%-6.52%-12.66%-19.4%-24.64%-34.77%
Operating Income Growth %--0.65%-1.55%-1.67%-0.52%-0.32%-0.61%
EBITDA+-10.12M-16.98M-43.9M-117.41M-177.53M-233.5M-376.16M
EBITDA Margin %-26.69%-7.32%-6.47%-12.59%-19.25%-24.42%-34.52%
EBITDA Growth %--0.68%-1.59%-1.67%-0.51%-0.32%-0.61%
D&A (Non-Cash Add-back)383K348K373K639K1.39M2.1M2.78M
EBIT-10.5M-17.35M-44.15M-118.05M-178.91M-235.6M-378.94M
Net Interest Income+-718K-7.39M-3K104K4.97M23.97M56.88M
Interest Income00206K104K4.97M23.97M56.88M
Interest Expense718K7.39M209K0000
Other Income/Expense-718K-7.4M-78K42K4.92M23.38M56.63M
Pretax Income+-11.22M-24.73M-44.35M-118.01M-174M-212.22M-322.3M
Pretax Margin %-29.59%-10.67%-6.54%-12.65%-18.86%-22.2%-29.58%
Income Tax+718K000000
Effective Tax Rate %1.06%1%1%1%1%1%1%
Net Income+-11.93M-24.73M-44.35M-118.01M-174M-212.22M-322.3M
Net Margin %-31.49%-10.67%-6.54%-12.65%-18.86%-22.2%-29.58%
Net Income Growth %--1.07%-0.79%-1.66%-0.47%-0.22%-0.52%
Net Income (Continuing)-11.22M-24.73M-44.35M-118.01M-174M-212.22M-322.3M
Discontinued Operations0000000
Minority Interest0000000
EPS (Diluted)+-0.58-0.86-2.05-2.85-3.34-2.91-2.89
EPS Growth %--0.48%-1.38%-0.39%-0.17%0.13%0.01%
EPS (Basic)-0.58-0.86-2.05-2.85-3.34-2.91-2.89
Diluted Shares Outstanding20.68M37.51M21.66M41.43M52.16M73.01M111.58M
Basic Shares Outstanding20.68M37.51M21.66M41.43M52.16M73.01M111.58M
Dividend Payout Ratio-------

Balance Sheet

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+3.24M95.68M331.68M411.14M622.94M611.31M1.54B
Cash & Short-Term Investments3.09M94.58M328.14M405.54M610.73M595.35M1.5B
Cash Only3.09M94.58M321.46M320.45M340.4M185.08M219.87M
Short-Term Investments006.68M85.09M270.33M410.27M1.28B
Accounts Receivable001.2M900K3.88M8.62M28.22M
Days Sales Outstanding--64.5435.22153.34329.23945.31
Inventory0000000
Days Inventory Outstanding-------
Other Current Assets152K000000
Total Non-Current Assets+740K1.23M2.22M16.44M15.86M17.25M21.61M
Property, Plant & Equipment702K631K1.92M15.59M15.01M16.65M18.29M
Fixed Asset Turnover0.54x3.68x3.53x0.60x0.61x0.57x0.60x
Goodwill0000000
Intangible Assets0000000
Long-Term Investments0000000
Other Non-Current Assets38K600K298K850K849K596K3.32M
Total Assets+3.98M96.91M333.9M427.58M638.8M628.55M1.56B
Asset Turnover0.10x0.02x0.02x0.02x0.01x0.02x0.01x
Asset Growth %-23.34%2.45%0.28%0.49%-0.02%1.49%
Total Current Liabilities+4.62M10.24M14.59M29.66M51.91M80.68M98.02M
Accounts Payable1.56M2.31M7.75M2.81M4.64M8.81M8.46M
Days Payables Outstanding67.71-75.1810.121.22K1.53K-
Short-Term Debt2.75M2.77M00000
Deferred Revenue (Current)01000K001000K1000K1000K
Other Current Liabilities305K03.69M4.86M11.19M14.34M3.66M
Current Ratio0.70x9.35x22.74x13.86x12.00x7.58x15.73x
Quick Ratio0.70x9.35x22.74x13.86x12.00x7.58x15.73x
Cash Conversion Cycle-------
Total Non-Current Liabilities+40.49M152.03M13.09M16.49M8.82M47.11M40.92M
Long-Term Debt7.58M1.77M00000
Capital Lease Obligations0393K938K9.96M7.58M6.21M2.96M
Deferred Tax Liabilities0134.72M00000
Other Non-Current Liabilities32.92M45K12.15M6.53M000
Total Liabilities45.11M162.26M27.68M46.15M60.73M127.79M138.94M
Total Debt+10.32M4.94M938K11.73M10.69M9.85M6.8M
Net Debt7.23M-89.64M-320.52M-308.72M-329.71M-175.23M-213.07M
Debt / Equity--0.00x0.03x0.02x0.02x0.00x
Debt / EBITDA-------
Net Debt / EBITDA-------
Interest Coverage-14.62x-2.35x-211.85x----
Total Equity+-41.13M-65.36M306.22M381.43M578.08M500.76M1.42B
Equity Growth %--0.59%5.69%0.25%0.52%-0.13%1.85%
Book Value per Share-1.99-1.7414.149.2111.086.8612.77
Total Shareholders' Equity-41.13M-65.36M306.22M381.43M578.08M500.76M1.42B
Common Stock426K1K4K5K7K8K12K
Retained Earnings-41.55M-22.18M-66.54M-184.55M-358.54M-570.76M-893.07M
Treasury Stock0000000
Accumulated OCI-33.12M-134.72M-5K-187K-2.7M125K2.9M
Minority Interest0000000

Cash Flow

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-9.65M2.49M-37.12M-94.81M-136.27M-119.06M-300.87M
Operating CF Margin %-25.47%1.07%-5.47%-10.17%-14.77%-12.45%-27.61%
Operating CF Growth %-1.26%-15.91%-1.55%-0.44%0.13%-1.53%
Net Income-11.22M-24.73M-44.35M-118.01M-174M-212.22M-322.3M
Depreciation & Amortization383K348K373K639K1.39M2.1M2.78M
Stock-Based Compensation60K406K4.31M17.06M27.14M38.22M51.36M
Deferred Taxes0084K0000
Other Non-Cash Items447K7.11M139K163K-615K-8.3M-18.15M
Working Capital Changes671K19.36M2.33M5.34M9.82M61.13M-14.56M
Change in Receivables0000000
Change in Inventory0000000
Change in Payables780K436K5.75M6.04M18.32M1.77M35.18M
Cash from Investing+-49K-235K-7.79M-82.52M-189.96M-130.07M-854.2M
Capital Expenditures-49K-235K-1.09M-3.74M-2.82M-4.23M-7.07M
CapEx % of Revenue0.13%0.1%0.16%0.4%0.31%0.44%0.65%
Acquisitions-------
Investments-------
Other Investing000-82.52M-187.13M00
Cash from Financing+5.14M89.23M272.04M176.32M346.17M93.86M1.19B
Debt Issued (Net)-------
Equity Issued (Net)-------
Dividends Paid0-106K00000
Share Repurchases-------
Other Financing162K65K466K1.64M1.39M2.13M191.81M
Net Change in Cash-------
Free Cash Flow+-9.7M2.25M-38.21M-98.55M-139.09M-123.29M-307.94M
FCF Margin %-25.6%0.97%-5.63%-10.57%-15.08%-12.9%-28.26%
FCF Growth %-1.23%-17.94%-1.58%-0.41%0.11%-1.5%
FCF per Share-0.470.06-1.76-2.38-2.67-1.69-2.76
FCF Conversion (FCF/Net Income)0.81x-0.10x0.84x0.80x0.78x0.56x0.93x
Interest Paid0322K00000
Taxes Paid0000000

Key Ratios

Metric2018201920202021202220232024
Return on Equity (ROE)---36.83%-34.32%-36.27%-39.34%-33.47%
Return on Invested Capital (ROIC)----303.16%-83.58%-61.58%-36.97%
Gross Margin-2125.86%100%-454.03%-984.95%84.96%78.02%100%
Net Margin-3148.81%-1066.58%-653.53%-1265.38%-1886.33%-2219.87%-2957.71%
Debt / Equity--0.00x0.03x0.02x0.02x0.00x
Interest Coverage-14.62x-2.35x-211.85x----
FCF Conversion0.81x-0.10x0.84x0.80x0.78x0.56x0.93x
Revenue Growth-511.87%192.67%37.41%-1.09%3.64%13.99%

Revenue by Segment

2024
Reportable10.9M
Reportable Growth-

Frequently Asked Questions

Growth & Financials

Avidity Biosciences, Inc. (RNA) reported $20.9M in revenue for fiscal year 2024. This represents a 5406% increase from $0.4M in 2018.

Avidity Biosciences, Inc. (RNA) grew revenue by 14.0% over the past year. This is steady growth.

Avidity Biosciences, Inc. (RNA) reported a net loss of $549.8M for fiscal year 2024.

Dividend & Returns

Avidity Biosciences, Inc. (RNA) has a return on equity (ROE) of -33.5%. Negative ROE indicates the company is unprofitable.

Avidity Biosciences, Inc. (RNA) had negative free cash flow of $595.4M in fiscal year 2024, likely due to heavy capital investments.

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