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VYNE
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VYNEVYNE Therapeutics Inc.
$39.50$26M
Overview & Tools
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Valuation & Forecasts
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Price & Analyst Data
Analyst TargetsPrice History
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Income StatementBalance SheetCash FlowRatios & Margins
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
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VYNE logo

VYNE Therapeutics Inc.

VYNE
NASDAQ · Biotechnology
$39.50
At close - Sep 4, 4:00 PM EDT - USD
Market Cap$26M
P/E-1.3x
52W High$46.95
Volume207.32K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Clinical Development Burn Outpaces Revenue Generation

VYNE Therapeutics operates as a high-risk, clinical-stage entity where value is almost entirely dependent on the success of the VYN201 program rather than commercial operations. The company faces significant financial headwinds, characterized by a persistent r...

GrowthContracting
ProfitabilityNegative
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

VYNE price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

7/12 Beats

EPS beat 7 of last 12 quarters

02

Valuation risk

-104% Peers

P/E is 104% below peer median

03

Market leadership

RS 84 · Leader

High momentum (Outperforming 84% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystEstimated earnings · Aug 15

Market performance

Price History →

Trailing total returns as of 10/10/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
VYNE+106.97%
S&P 500 (^GSPC)+13.29%
1-Year Return
VYNE+179.07%
S&P 500 (^GSPC)+14.98%
3-Year Return
VYNE-64.81%
S&P 500 (^GSPC)+83.22%
5-Year Return
VYNE-94.62%
S&P 500 (^GSPC)+76.04%

Growth & profitability

Annual revenue & EPS trend
Revenue
$570K+13.8% YoY
Net income
-$26M+33.5% YoY
Free cash flow
-$33M+2.8% YoY
Operating margin
-5219.1%+3490.9 pts YoY
ROIC (TTM)-124%
Avg ROIC 5Y-
ROE (TTM)-66.3%
Piotroski Score2 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate7/12 (58%)
Revenue Beat Rate4/12 (33%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026Latest
May 15, 2026
-$0.08+55.6%
vs -$0.18
$86,000-57.0%
vs $200,000
Q2 2026
Mar 12, 2026
-$0.28-40.0%
vs -$0.20
$130,000-25.7%
vs $175,000
Q4 2025
Nov 6, 2025
-$0.17+10.5%
vs -$0.19
$169,000+35.2%
vs $125,000
Q3 2025
Aug 14, 2025
-$0.13+43.5%
vs -$0.23
$69,000-65.5%
vs $200,000
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

3 Stories
Business Wire·Jul 27, 2026
Yarrow Bioscience Announces Closing of Merger with VYNE Therapeutics and Initiation of Dosing in Phase 2a/2b Trial of YB-101, a Potential First-in-Class Treatment for Graves' Disease and Thyroid Eye Disease

NEW HAVEN, Conn.--(BUSINESS WIRE)--Yarrow Bioscience, Inc. (“Yarrow” or the “Company”) (Nasdaq: YARW), a clinical-stage biotechnology company focused on developing transformative therapies for autoimmune thyroid diseases, today announced the completion of its merger with VYNE Therapeutics Inc. (“VYNE”), and the previously announced private financings totaling approximately $200 million. The combined company will operate as Yarrow Bioscience, Inc., with its shares expected to begin trading on th.

GlobeNewsWire·Jul 23, 2026
VYNE Therapeutics Provides Update Regarding Cash Dividend, Reverse Stock Split and Anticipated Timing of Closing of the Proposed Merger with Yarrow Bioscience

NEW YORK, July 23, 2026 (GLOBE NEWSWIRE) --  VYNE Therapeutics Inc. (Nasdaq: VYNE) (“VYNE” or the “Company”) today announced that its previously announced special cash dividend (the “Cash Dividend”), declared in connection with the terms and conditions of the Agreement and Plan of Merger and Reorganization, entered into on December 17, 2025, as amended (the “Merger Agreement”), with Yarrow Bioscience, Inc. (“Yarrow”) and Yellow Merger Sub Corp., was distributed, in cash, on July 23, 2026 to VYNE's stockholders of record as of July 22, 2026 (the “Record Date”), subject to the Nasdaq due bill procedures described below, based on their holdings as of the Record Date and during the Due Bill Period (as defined below) and prior to the reverse stock split.

GlobeNewsWire·Jul 21, 2026
VYNE Therapeutics Announces 1-for-50 Reverse Stock Split and Provides Update Regarding Special Dividend in Connection with the Proposed Merger with Yarrow Bioscience

NEW YORK, July 21, 2026 (GLOBE NEWSWIRE) -- VYNE Therapeutics Inc. (Nasdaq: VYNE) (“VYNE” or the “Company”) today announced that its Board of Directors has approved a reverse stock split of VYNE's common stock at a ratio of 1-for-50 in connection with the anticipated closing of the proposed merger (the “Merger”) with Yarrow Bioscience, Inc. (“Yarrow”). The reverse stock split was previously approved by VYNE's stockholders at VYNE's special meeting in lieu of the annual meeting of stockholders held on July 16, 2026 (the “Special Meeting”).

Filtered for VYNE Therapeutics Inc.More Headlines
04

Compare before deciding

Benchmark VYNE against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for VYNE Therapeutics Inc. (VYNE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
VYNE logoVYNEVYNE Therapeutics Inc.Current
$39.50$26.37M-1.2713.77%-4646.14%-66.33%—
DERM logoDERMJourney Medical Corporation
$5.95$163.75M-12.6610.2%-8.95%-20.23%—
PRGO logoPRGOPerrigo Company plc
$14.50$2.01B-1.41-2.75%-41.85%-55.97%—
SKIN logoSKINSkinHealth Systems Inc.
$0.57$73.73M-3.56-10.02%-9.79%-47.84%—
ORGO logoORGOOrganogenesis Holdings Inc.
$1.28$164.7M8.5316.8%-19.76%-24.23%—
GDRX logoGDRXGoodRx Holdings, Inc.
$3.36$1.16B39.390.57%2.07%2.61%—

Compare VYNE vs Peers

VYNE Therapeutics Inc. (VYNE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs DERM

Most directly comparable listed peer for VYNE.

Scale Benchmark

vs MCK

Larger-name benchmark to compare VYNE against a more recognizable public peer.

Peer Set

Compare Top 5

vs DERM, PRGO, SKIN, ORGO

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

VYNE SEC Filings & Documents

VYNE Therapeutics Inc. (VYNE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 30, 2026·SEC

Material company update

Jul 28, 2026·SEC

Material company update

Jul 21, 2026·SEC

10-K Annual Reports

4
FY 2026

Feb 27, 2026·SEC

FY 2025

Mar 6, 2025·SEC

FY 2024

Mar 1, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 13, 2026·SEC

FY 2026

May 15, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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VYNE Frequently Asked Questions

VYNE Therapeutics Inc. (VYNE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is VYNE Therapeutics Inc.'s revenue?

VYNE Therapeutics Inc. (VYNE) reported $1.0M in revenue for fiscal year 2025.

How fast is VYNE Therapeutics Inc. growing?

VYNE Therapeutics Inc. (VYNE) grew revenue by 13.8% over the past year. This is steady growth.

Is VYNE profitable?

VYNE Therapeutics Inc. (VYNE) reported a net loss of $42.2M for fiscal year 2025.

Dividend & Returns
What is VYNE's return on equity?

VYNE Therapeutics Inc. (VYNE) has a return on equity (ROE) of -66.3%. Negative ROE indicates the company is unprofitable.

What is VYNE Therapeutics Inc.'s free cash flow?

VYNE Therapeutics Inc. (VYNE) had negative free cash flow of $16.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in VYNE back in 2015?

Total return calculator · dividends reinvested · 11+ years of data

See returns →