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XERSXeris Biopharma Holdings, Inc.
$9.25$1.6B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
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XERS logo

Xeris Biopharma Holdings, Inc.

XERS
NASDAQ · Biotechnology
$9.25
At close - Oct 1, 4:00 PM EDT - USD
Market Cap$1.6B
P/E2890.6x
52W High$11.33
Volume2.92M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Revenue Acceleration Offsets Leverage and Equity Risks

Xeris Biopharma is executing a sharp revenue acceleration, with 28.7% YoY growth in 2026Q2 and gross margins expanding to 86.4%, signaling strong commercial traction and pricing power. Operating leverage is emerging as operating income turned positive at $5.2M...

GrowthAccelerating
ProfitabilityStable
ValuationExpensive
TechnicalsStrong
Explore valuation models
MARKET ACTION

XERS price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

8/12 Beats

EPS beat 8 of last 12 quarters

02

Valuation risk

+8590% Peers

P/E is 8590% above peer median

03

Market leadership

RS 88 · Leader

High momentum (Outperforming 88% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystEstimated earnings · Nov 6

Market performance

Price History →

Trailing total returns as of 10/3/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
XERS+25.85%
S&P 500 (^GSPC)+11.83%
1-Year Return
XERS+15.48%
S&P 500 (^GSPC)+14.29%
3-Year Return
XERS+428.57%
S&P 500 (^GSPC)+70.42%
5-Year Return
XERS+274.49%
S&P 500 (^GSPC)+67.65%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E
2837.5x
Forward P/E
N/A
EV/EBITDA100th %ile
40.3x
FCF YieldCash Flow
1.8%

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
2837.5x
N/A
N/A
EV/EBITDA
40.3x
34.6x
100th· High
Price/FCF
56.1x
48.6x
100th· High
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$3.80-58.9%
Base (Fair)$6.89-24.3%
Bull$7.81-15.6%
$3.80 Bear$6.89 Base$7.81 Bull
Current Market Price: $9.25
Trades at a 34.3% premium to Base DCF ($6.89)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue
$292M+43.7% YoY
Net income
$554K+101.0% YoY
Free cash flow
$28M+173.8% YoY
Operating margin
8.5%+25.1 pts YoY
ROIC (TTM)33.8%
Avg ROIC 5Y-
ROE (TTM)4%
Piotroski Score7 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate8/12 (67%)
Revenue Beat Rate8/12 (67%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 6, 2026
-$0.18-1582.7%
vs $0.01
$91M+1.0%
vs $90M
Q2 2026
May 7, 2026
$0.01+465.0%
vs -$0.00
$82M+3.3%
vs $80M
Q2 2026
Mar 2, 2026
$0.06+100.0%
vs $0.03
$86M+4.4%
vs $82M
Q4 2025
Nov 6, 2025
$0.00-65.0%
vs $0.01
$74M-13.5%
vs $86M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Defense World·Sep 21, 2026
Xeris Biopharma Holdings, Inc. (NASDAQ:XERS) Given Average Recommendation of “Hold” by Analysts

Shares of Xeris Biopharma Holdings, Inc. (NASDAQ: XERS - Get Free Report) have received an average rating of "Hold" from the seven ratings firms that are presently covering the firm, MarketBeat reports. One equities research analyst has rated the stock with a sell recommendation, two have assigned a hold recommendation and four have issued a buy

Seeking Alpha·Sep 9, 2026
Xeris Biopharma Holdings, Inc. (XERS) Discusses XP-8121 Program Overview, Phase 3 Study Details and Commercial Strategy Transcript

Xeris Biopharma Holdings, Inc. (XERS) Discusses XP-8121 Program Overview, Phase 3 Study Details and Commercial Strategy Transcript

Defense World·Aug 31, 2026
Connor Clark & Lunn Investment Management Ltd. Takes $1.01 Million Position in Xeris Biopharma Holdings, Inc. $XERS

Connor Clark and Lunn Investment Management Ltd. bought a new position in shares of Xeris Biopharma Holdings, Inc. (NASDAQ: XERS) during the second quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The fund bought 127,107 shares of the company's stock, valued at approximately $1,007,000. Connor

Defense World·Aug 27, 2026
Xeris Biopharma Holdings, Inc. (NASDAQ:XERS) Given Average Recommendation of “Hold” by Brokerages

Xeris Biopharma Holdings, Inc. (NASDAQ: XERS - Get Free Report) has received an average recommendation of "Hold" from the six brokerages that are covering the firm, MarketBeat Ratings reports. One investment analyst has rated the stock with a sell rating, two have issued a hold rating and three have assigned a buy rating to the company.

Filtered for Xeris Biopharma Holdings, Inc.More Headlines
04

Compare before deciding

Benchmark XERS against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Xeris Biopharma Holdings, Inc. (XERS)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
XERS logoXERSXeris Biopharma Holdings, Inc.Current
$9.25$1.6B2890.6343.72%0.19%4.05%—
LNTH logoLNTHLantheus Holdings, Inc.
$99.65$6.49B29.220.5%17.69%23.27%—
SUPN logoSUPNSupernus Pharmaceuticals, Inc.
$42.18$2.45B-62.038.63%-13.23%-10.42%—
PAHC logoPAHCPhibro Animal Health Corporation
$35.87$1.45B30.1427.37%6.57%28.67%—
CORT logoCORTCorcept Therapeutics Incorporated
$114.03$12.24B139.0512.79%6.61%8.37%—
AMRX logoAMRXAmneal Pharmaceuticals, Inc.
$20.07$6.41B91.238.05%5.05%——

Compare XERS vs Peers

Xeris Biopharma Holdings, Inc. (XERS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs LNTH

Most directly comparable listed peer for XERS.

Scale Benchmark

vs LLY

Larger-name benchmark to compare XERS against a more recognizable public peer.

Peer Set

Compare Top 5

vs LNTH, SUPN, PAHC, CORT

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

XERS SEC Filings & Documents

Xeris Biopharma Holdings, Inc. (XERS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jul 17, 2026·SEC

Material company update

Jun 30, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 2, 2026·SEC

FY 2025

Mar 6, 2025·SEC

FY 2024

Mar 6, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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XERS Frequently Asked Questions

Xeris Biopharma Holdings, Inc. (XERS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Xeris Biopharma Holdings, Inc.'s revenue?

Xeris Biopharma Holdings, Inc. (XERS) reported $335.4M in revenue for fiscal year 2025. This represents a 31101% increase from $1.1M in 2016.

How fast is Xeris Biopharma Holdings, Inc. growing?

Xeris Biopharma Holdings, Inc. (XERS) grew revenue by 43.7% over the past year. This is strong growth.

Is XERS profitable?

Xeris Biopharma Holdings, Inc. (XERS) reported a net loss of $17.2M for fiscal year 2025.

Dividend & Returns
What is XERS's return on equity?

Xeris Biopharma Holdings, Inc. (XERS) has a return on equity (ROE) of 4.0%. This is below average, suggesting room for improvement.

What is Xeris Biopharma Holdings, Inc.'s free cash flow?

Xeris Biopharma Holdings, Inc. (XERS) generated $64.9M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in XERS back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →