Comprehensive Stock Comparison
Compare Nurix Therapeutics, Inc. (NRIX) vs Recursion Pharmaceuticals, Inc. (RXRX) Stock
Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.
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Quick Verdict
| Category | Winner | Why |
|---|---|---|
| Growth | NRIX | 54.0% revenue growth vs RXRX's 26.9% |
| Quality / Margins | NRIX | -314.9% net margin vs RXRX's -8.6% |
| Stability / Safety | NRIX | Beta 1.19 vs RXRX's 2.38 |
| Dividends | Tie | Neither pays a meaningful dividend |
| Momentum (1Y) | NRIX | +3.4% vs RXRX's -51.1% |
| Efficiency (ROA) | NRIX | -38.4% ROA vs RXRX's -43.7%, ROIC -54.0% vs -95.8% |
Who Each Stock Is For
Income & stability
Growth exposure
Long-term compounding (10Y)
Sleep-well-at-night portfolio
Defensive / Recession hedge
Business Model
What each company does and how it makes money
Nurix Therapeutics is a clinical-stage biopharmaceutical company developing targeted protein degradation therapies for cancer and immune disorders. It generates revenue primarily through strategic collaborations and licensing deals — including partnerships with Gilead Sciences and Sanofi — while advancing its own pipeline of oral BTK degraders and CBL-B inhibitors. The company's key advantage is its proprietary DELigase platform for discovering novel protein degraders, which could enable treatments for diseases that have been difficult to target with conventional small molecules.
Recursion Pharmaceuticals is a clinical-stage biotechnology company that uses an industrialized, technology-driven platform to discover and develop new drugs. It generates revenue primarily through research collaborations and partnerships with pharmaceutical companies — like its major deal with Bayer — while advancing its own pipeline of drug candidates. Its key competitive advantage is its proprietary platform that combines automation, artificial intelligence, and massive biological datasets to systematically decode biology and accelerate drug discovery at scale.
Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Financial Metrics Comparison
Side-by-side fundamentals across 2 stocks. BestLagging
Financial Scorecard
NRIX leads in 4 of 6 categories — strongest in Valuation Metrics and Profitability & Efficiency. 1 category is tied.
Financial Metrics (TTM)
NRIX and RXRX operate at a comparable scale, with $84M and $75M in trailing revenue. NRIX is the more profitable business, keeping -3.1% of every revenue dollar as net income compared to RXRX's -8.6%. On growth, RXRX holds the edge at +6.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | NRIXNurix Therapeutic… | RXRXRecursion Pharmac… |
|---|---|---|
| RevenueTrailing 12 months | $84M | $75M |
| EBITDAEarnings before interest/tax | -$267M | -$564M |
| Net IncomeAfter-tax profit | -$264M | -$645M |
| Free Cash FlowCash after capex | -$263M | -$378M |
| Gross MarginGross profit ÷ Revenue | -87.4% | -32.1% |
| Operating MarginEBIT ÷ Revenue | -3.4% | -8.7% |
| Net MarginNet income ÷ Revenue | -3.1% | -8.6% |
| FCF MarginFCF ÷ Revenue | -3.1% | -5.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +2.2% | +6.9% |
| EPS Growth (YoY)Latest quarter vs prior year | -9.3% | +60.4% |
Valuation Metrics
| Metric | NRIXNurix Therapeutic… | RXRXRecursion Pharmac… |
|---|---|---|
| Market CapShares × price | $1.6B | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $1.4B | $1.3B |
| Trailing P/EPrice ÷ TTM EPS | -5.24x | -2.55x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 19.36x | 25.96x |
| Price / BookPrice ÷ Book value/share | 2.57x | 1.45x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
NRIX delivers a -49.1% return on equity — every $100 of shareholder capital generates $-49 in annual profit, vs $-57 for RXRX. RXRX carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to NRIX's 0.10x.
| Metric | NRIXNurix Therapeutic… | RXRXRecursion Pharmac… |
|---|---|---|
| ROE (TTM)Return on equity | -49.1% | -57.0% |
| ROA (TTM)Return on assets | -38.4% | -43.7% |
| ROICReturn on invested capital | -54.0% | -95.8% |
| ROCEReturn on capital employed | -48.6% | -50.1% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.10x | 0.07x |
| Net DebtTotal debt minus cash | -$191M | -$665M |
| Cash & Equiv.Liquid assets | $247M | $743M |
| Total DebtShort + long-term debt | $56M | $78M |
| Interest CoverageEBIT ÷ Interest expense | — | -491.16x |
Total Returns (with DRIP)
A $10,000 investment in NRIX five years ago would be worth $4,406 today (with dividends reinvested), compared to $2,039 for RXRX. Over the past 12 months, NRIX leads with a +3.4% total return vs RXRX's -51.1%. The 3-year compound annual growth rate (CAGR) favors NRIX at 19.2% vs RXRX's -23.4% — a key indicator of consistent wealth creation.
| Metric | NRIXNurix Therapeutic… | RXRXRecursion Pharmac… |
|---|---|---|
| YTD ReturnYear-to-date | -11.6% | -12.6% |
| 1-Year ReturnPast 12 months | +3.4% | -51.1% |
| 3-Year ReturnCumulative with dividends | +69.4% | -55.0% |
| 5-Year ReturnCumulative with dividends | -55.9% | -79.6% |
| 10-Year ReturnCumulative with dividends | -16.0% | -79.6% |
| CAGR (3Y)Annualised 3-year return | +19.2% | -23.4% |
Risk & Volatility
NRIX is the less volatile stock with a 1.19 beta — it tends to amplify market swings less than RXRX's 2.38 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NRIX currently trades 71.0% from its 52-week high vs RXRX's 46.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | NRIXNurix Therapeutic… | RXRXRecursion Pharmac… |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.19x | 2.38x |
| 52-Week HighHighest price in past year | $22.50 | $7.89 |
| 52-Week LowLowest price in past year | $8.18 | $2.98 |
| % of 52W HighCurrent price vs 52-week peak | +71.0% | +46.5% |
| RSI (14)Momentum oscillator 0–100 | 45.3 | 46.7 |
| Avg Volume (50D)Average daily shares traded | 946K | 18.2M |
Analyst Outlook
Wall Street rates NRIX as "Buy" and RXRX as "Hold". Consensus price targets imply 199.7% upside for RXRX (target: $11) vs 95.5% for NRIX (target: $31).
| Metric | NRIXNurix Therapeutic… | RXRXRecursion Pharmac… |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Hold |
| Price TargetConsensus 12-month target | $31.22 | $11.00 |
| # AnalystsCovering analysts | 17 | 10 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Historical Charts
Charts are rendered on first load. Hover for details.
Chart 1Total Return — 5 Years (Rebased to 100)
| Stock | May 21 | Feb 26 | Change |
|---|---|---|---|
| Nurix Therapeutics,… (NRIX) | 100 | 50.7 | -49.3% |
| Recursion Pharmaceu… (RXRX) | 183.44 | 23.22 | -87.3% |
Nurix Therapeutics,… (NRIX) returned -56% over 5 years vs Recursion Pharmaceu… (RXRX)'s -80%.
Chart 2Revenue Growth — 10 Years
| Stock | 2018 | 2025 | Change |
|---|---|---|---|
| Nurix Therapeutics,… (NRIX) | $37M | $84M | +124.3% |
| Recursion Pharmaceu… (RXRX) | $2M | $75M | +4264.8% |
Nurix Therapeutics, Inc.'s revenue grew from $37M (2018) to $84M (2025) — a 12.2% CAGR.
Chart 3Net Margin Trend — 10 Years
| Stock | 2018 | 2025 | Change |
|---|---|---|---|
| Nurix Therapeutics,… (NRIX) | -25.2% | -3.1% | +87.5% |
| Recursion Pharmaceu… (RXRX) | -36.5% | -8.6% | +76.4% |
Nurix Therapeutics, Inc.'s net margin went from -25% (2018) to -3% (2025).
Chart 4EPS Growth — 10 Years
| Stock | 2018 | 2025 | Change |
|---|---|---|---|
| Nurix Therapeutics,… (NRIX) | -0.59 | -3.05 | -416.9% |
| Recursion Pharmaceu… (RXRX) | -0.37 | -1.44 | -285.9% |
Nurix Therapeutics, Inc.'s EPS grew from $-0.59 (2018) to $-3.05 (2025).
Chart 5Free Cash Flow — 5 Years
Nurix Therapeutics, Inc. generated $-263M FCF in 2025 (-193% vs 2021). Recursion Pharmaceuticals, Inc. generated $-378M FCF in 2025 (-91% vs 2021).
NRIX vs RXRX: Frequently Asked Questions
7 questions · data-driven answers · updated daily
01Is NRIX or RXRX a better buy right now?
Analysts rate Nurix Therapeutics, Inc. (NRIX) a "Buy" — based on 17 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — NRIX or RXRX?
Over the past 5 years, Nurix Therapeutics, Inc. (NRIX) delivered a total return of -55.9%, compared to -79.6% for Recursion Pharmaceuticals, Inc. (RXRX). A $10,000 investment in NRIX five years ago would be worth approximately $4K today (assuming dividends reinvested). Over 10 years, the gap is even starker: NRIX returned -16.0% versus RXRX's -79.6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — NRIX or RXRX?
By beta (market sensitivity over 5 years), Nurix Therapeutics, Inc. (NRIX) is the lower-risk stock at 1.19β versus Recursion Pharmaceuticals, Inc.'s 2.38β — meaning RXRX is approximately 99% more volatile than NRIX relative to the S&P 500. On balance sheet safety, Recursion Pharmaceuticals, Inc. (RXRX) carries a lower debt/equity ratio of 7% versus 10% for Nurix Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which has better profit margins — NRIX or RXRX?
Nurix Therapeutics, Inc. (NRIX) is the more profitable company, earning -314.9% net margin versus -863.4% for Recursion Pharmaceuticals, Inc. — meaning it keeps -314.9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NRIX leads at -340.2% versus -867.9% for RXRX. At the gross margin level — before operating expenses — NRIX leads at 77.5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
05Which pays a better dividend — NRIX or RXRX?
None of the stocks in this comparison currently pay a material dividend. All are effectively zero-yield and should be held for capital appreciation rather than income.
06Is NRIX or RXRX better for a retirement portfolio?
For long-horizon retirement investors, Nurix Therapeutics, Inc. (NRIX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.19)). Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 2.38 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NRIX: -16.0%, RXRX: -79.6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
07What are the main differences between NRIX and RXRX?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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