Comprehensive Stock Comparison

Compare Seer, Inc. (SEER) vs Cardio Diagnostics Holdings, Inc. (CDIO) Stock

Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.

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Quick Verdict

CategoryWinnerWhy
GrowthCDIO logoCDIO104.5% revenue growth vs SEER's -8.1%
Quality / MarginsSEER logoSEER-486.0% net margin vs CDIO's -415.2%
Stability / SafetySEER logoSEERBeta 0.52 vs CDIO's 2.02, lower leverage
DividendsTieNeither pays a meaningful dividend
Momentum (1Y)SEER logoSEER-9.3% vs CDIO's -62.1%
Efficiency (ROA)SEER logoSEER-25.7% ROA vs CDIO's -74.5%, ROIC -21.3% vs -222.7%
Bottom line: SEER leads in 4 of 6 categories, making it the stronger pick for investors who prioritize profitability and margin quality and capital preservation and lower volatility. Cardio Diagnostics Holdings, Inc. is the better choice for growth and revenue expansion. As direct sector peers, they can serve as alternatives in the same portfolio allocation.

Who Each Stock Is For

Income & stability

Growth exposure

Long-term compounding (10Y)

Sleep-well-at-night portfolio

Defensive / Recession hedge

Business Model

What each company does and how it makes money

SEERSeer, Inc.
Healthcare

Seer is a life sciences company that develops and commercializes proteomics technology to analyze proteins for research and drug discovery. It generates revenue primarily from sales of its Proteograph Product Suite — an integrated system of consumables, automation instruments, and software — to academic institutions, biopharma companies, and research laboratories. The company's competitive advantage lies in its proprietary technology platform that enables deep, unbiased proteomic analysis at scale, which could accelerate biomarker discovery and therapeutic development.

CDIOCardio Diagnostics Holdings, Inc.
Healthcare

Cardio Diagnostics develops and commercializes epigenetics-based clinical tests for cardiovascular disease risk assessment. It generates revenue primarily from sales of its Epi+Gen CHD test—a three-year symptomatic coronary heart disease risk assessment—to healthcare providers and through laboratory services. The company's moat lies in its proprietary epigenetic technology platform that offers more personalized cardiovascular risk prediction than traditional methods.

Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

SEERSeer, Inc.
FY 2023
Grant
100.0%$1M
CDIOCardio Diagnostics Holdings, Inc.

Segment breakdown not available.

Financial Metrics Comparison

Side-by-side fundamentals across 2 stocks. BestLagging

Financial Scorecard

SEER logoSEER 5CDIO logoCDIO 0
Financial MetricsSEER logoSEER6/6 metrics
Valuation MetricsSEER logoSEER3/3 metrics
Profitability & EfficiencySEER logoSEER6/7 metrics
Total ReturnsSEER logoSEER5/6 metrics
Risk & VolatilitySEER logoSEER2/2 metrics
Analyst Outlook0/0 metrics

SEER leads in 5 of 6 categories — strongest in Financial Metrics and Valuation Metrics.

Financial Metrics (TTM)

SEER is the larger business by revenue, generating $16M annually — 1034.5x CDIO's $15,782. SEER is the more profitable business, keeping -4.9% of every revenue dollar as net income compared to CDIO's -415.2%. On growth, SEER holds the edge at +4.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricSEER logoSEERSeer, Inc.CDIO logoCDIOCardio Diagnostic…
RevenueTrailing 12 months$16M$15,782
EBITDAEarnings before interest/tax-$76M-$6M
Net IncomeAfter-tax profit-$79M-$7M
Free Cash FlowCash after capex-$46M-$6M
Gross MarginGross profit ÷ Revenue+40.7%-10.3%
Operating MarginEBIT ÷ Revenue-5.2%-414.2%
Net MarginNet income ÷ Revenue-4.9%-415.2%
FCF MarginFCF ÷ Revenue-2.8%-379.5%
Rev. Growth (YoY)Latest quarter vs prior year+4.5%-56.6%
EPS Growth (YoY)Latest quarter vs prior year+8.6%-15.3%
SEER leads this category, winning 6 of 6 comparable metrics.

Valuation Metrics

MetricSEER logoSEERSeer, Inc.CDIO logoCDIOCardio Diagnostic…
Market CapShares × price$103M$141M
Enterprise ValueMkt cap + debt − cash$88M$135M
Trailing P/EPrice ÷ TTM EPS-1.33x-0.57x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue7.40x4054.38x
Price / BookPrice ÷ Book value/share0.35x14.80x
Price / FCFMarket cap ÷ FCF
SEER leads this category, winning 3 of 3 comparable metrics.

Profitability & Efficiency

SEER delivers a -29.2% return on equity — every $100 of shareholder capital generates $-29 in annual profit, vs $-80 for CDIO. SEER carries lower financial leverage with a 0.08x debt-to-equity ratio, signaling a more conservative balance sheet compared to CDIO's 0.10x.

MetricSEER logoSEERSeer, Inc.CDIO logoCDIOCardio Diagnostic…
ROE (TTM)Return on equity-29.2%-80.4%
ROA (TTM)Return on assets-25.7%-74.5%
ROICReturn on invested capital-21.3%-2.2%
ROCEReturn on capital employed-25.9%-123.0%
Piotroski ScoreFundamental quality 0–944
Debt / EquityFinancial leverage0.08x0.10x
Net DebtTotal debt minus cash-$15M-$7M
Cash & Equiv.Liquid assets$41M$8M
Total DebtShort + long-term debt$26M$969,863
Interest CoverageEBIT ÷ Interest expense-418.04x
SEER leads this category, winning 6 of 7 comparable metrics.

Total Returns (with DRIP)

A $10,000 investment in SEER five years ago would be worth $427 today (with dividends reinvested), compared to $179 for CDIO. Over the past 12 months, SEER leads with a -9.3% total return vs CDIO's -62.1%. The 3-year compound annual growth rate (CAGR) favors SEER at -28.2% vs CDIO's -68.0% — a key indicator of consistent wealth creation.

MetricSEER logoSEERSeer, Inc.CDIO logoCDIOCardio Diagnostic…
YTD ReturnYear-to-date+1.6%+85.2%
1-Year ReturnPast 12 months-9.3%-62.1%
3-Year ReturnCumulative with dividends-62.9%-96.7%
5-Year ReturnCumulative with dividends-95.7%-98.2%
10-Year ReturnCumulative with dividends-96.7%-98.2%
CAGR (3Y)Annualised 3-year return-28.2%-68.0%
SEER leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

SEER is the less volatile stock with a 0.52 beta — it tends to amplify market swings less than CDIO's 2.02 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. SEER currently trades 76.8% from its 52-week high vs CDIO's 30.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSEER logoSEERSeer, Inc.CDIO logoCDIOCardio Diagnostic…
Beta (5Y)Sensitivity to S&P 5000.52x2.02x
52-Week HighHighest price in past year$2.41$17.39
52-Week LowLowest price in past year$1.62$0.97
% of 52W HighCurrent price vs 52-week peak+76.8%+30.2%
RSI (14)Momentum oscillator 0–10042.764.3
Avg Volume (50D)Average daily shares traded239K3.3M
SEER leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

MetricSEER logoSEERSeer, Inc.CDIO logoCDIOCardio Diagnostic…
Analyst RatingConsensus buy/hold/sellHold
Price TargetConsensus 12-month target
# AnalystsCovering analysts4
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap+11.4%0.0%
Insufficient data to determine a leader in this category.

Historical Charts

Charts are rendered on first load. Hover for details.

Chart 1Total Return — 5 Years (Rebased to 100)

StockFeb 22Mar 26Change
Seer, Inc. (SEER)1009.96-90.0%
Cardio Diagnostics … (CDIO)100.11.77-98.2%

Seer, Inc. (SEER) returned -96% over 5 years vs Cardio Diagnostics … (CDIO)'s -98%.

Chart 2Revenue Growth — 10 Years

Stock20182024Change
Seer, Inc. (SEER)$0.00$14M
Cardio Diagnostics … (CDIO)$0.00$34890.00

Seer, Inc.'s revenue grew from $0M (2018) to $14M (2024) — a 0.0% CAGR.

Chart 3Net Margin Trend — 10 Years

Stock20192024Change
Seer, Inc. (SEER)-138.3%-6.2%+95.5%
Cardio Diagnostics … (CDIO)-688.6%-240.3%+65.1%

Seer, Inc.'s net margin went from -138% (2019) to -6% (2024).

Chart 4EPS Growth — 10 Years

Stock20182024Change
Seer, Inc. (SEER)-0.29-1.39-379.3%
Cardio Diagnostics … (CDIO)-0.06-9.3-14522.6%

Seer, Inc.'s EPS grew from $-0.29 (2018) to $-1.39 (2024).

Chart 5Free Cash Flow — 5 Years

2021
$-53M
$-1M
2022
$-71M
$-5M
2023
$-66M
$-6M
2024
$-50M
$-5M
Seer, Inc. (SEER)Cardio Diagnostics … (CDIO)

Seer, Inc. generated $-50M FCF in 2024 (+7% vs 2021). Cardio Diagnostics Holdings, Inc. generated $-5M FCF in 2024 (-672% vs 2021).

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SEER vs CDIO: Frequently Asked Questions

7 questions · data-driven answers · updated daily

01

Is SEER or CDIO a better buy right now?

Analysts rate Seer, Inc. (SEER) a "Hold" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — SEER or CDIO?

Over the past 5 years, Seer, Inc. (SEER) delivered a total return of -95.7%, compared to -98.2% for Cardio Diagnostics Holdings, Inc. (CDIO). A $10,000 investment in SEER five years ago would be worth approximately $427 today (assuming dividends reinvested). Over 10 years, the gap is even starker: SEER returned -96.7% versus CDIO's -98.2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — SEER or CDIO?

By beta (market sensitivity over 5 years), Seer, Inc. (SEER) is the lower-risk stock at 0.52β versus Cardio Diagnostics Holdings, Inc.'s 2.02β — meaning CDIO is approximately 288% more volatile than SEER relative to the S&P 500. On balance sheet safety, Seer, Inc. (SEER) carries a lower debt/equity ratio of 8% versus 10% for Cardio Diagnostics Holdings, Inc. — giving it more financial flexibility in a downturn.

04

Which has better profit margins — SEER or CDIO?

Seer, Inc. (SEER) is the more profitable company, earning -620.9% net margin versus -240.3% for Cardio Diagnostics Holdings, Inc. — meaning it keeps -620.9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SEER leads at -717.7% versus -239.8% for CDIO. At the gross margin level — before operating expenses — CDIO leads at 100.0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

05

Which pays a better dividend — SEER or CDIO?

None of the stocks in this comparison currently pay a material dividend. All are effectively zero-yield and should be held for capital appreciation rather than income.

06

Is SEER or CDIO better for a retirement portfolio?

For long-horizon retirement investors, Seer, Inc. (SEER) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.52)). Cardio Diagnostics Holdings, Inc. (CDIO) carries a higher beta of 2.02 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SEER: -96.7%, CDIO: -98.2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

07

What are the main differences between SEER and CDIO?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Revenue Growth>
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(SEER: 4.5% · CDIO: -56.6%)