Comprehensive Stock Comparison
Compare Seer, Inc. (SEER) vs Cardio Diagnostics Holdings, Inc. (CDIO) Stock
Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.
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Quick Verdict
| Category | Winner | Why |
|---|---|---|
| Growth | 104.5% revenue growth vs SEER's -8.1% | |
| Quality / Margins | -486.0% net margin vs CDIO's -415.2% | |
| Stability / Safety | Beta 0.52 vs CDIO's 2.02, lower leverage | |
| Dividends | Tie | Neither pays a meaningful dividend |
| Momentum (1Y) | -9.3% vs CDIO's -62.1% | |
| Efficiency (ROA) | -25.7% ROA vs CDIO's -74.5%, ROIC -21.3% vs -222.7% |
Who Each Stock Is For
Income & stability
Growth exposure
Long-term compounding (10Y)
Sleep-well-at-night portfolio
Defensive / Recession hedge
Business Model
What each company does and how it makes money
Seer is a life sciences company that develops and commercializes proteomics technology to analyze proteins for research and drug discovery. It generates revenue primarily from sales of its Proteograph Product Suite — an integrated system of consumables, automation instruments, and software — to academic institutions, biopharma companies, and research laboratories. The company's competitive advantage lies in its proprietary technology platform that enables deep, unbiased proteomic analysis at scale, which could accelerate biomarker discovery and therapeutic development.
Cardio Diagnostics develops and commercializes epigenetics-based clinical tests for cardiovascular disease risk assessment. It generates revenue primarily from sales of its Epi+Gen CHD test—a three-year symptomatic coronary heart disease risk assessment—to healthcare providers and through laboratory services. The company's moat lies in its proprietary epigenetic technology platform that offers more personalized cardiovascular risk prediction than traditional methods.
Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Financial Metrics Comparison
Side-by-side fundamentals across 2 stocks. BestLagging
Financial Scorecard
SEER leads in 5 of 6 categories — strongest in Financial Metrics and Valuation Metrics.
Financial Metrics (TTM)
SEER is the larger business by revenue, generating $16M annually — 1034.5x CDIO's $15,782. SEER is the more profitable business, keeping -4.9% of every revenue dollar as net income compared to CDIO's -415.2%. On growth, SEER holds the edge at +4.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $16M | $15,782 |
| EBITDAEarnings before interest/tax | -$76M | -$6M |
| Net IncomeAfter-tax profit | -$79M | -$7M |
| Free Cash FlowCash after capex | -$46M | -$6M |
| Gross MarginGross profit ÷ Revenue | +40.7% | -10.3% |
| Operating MarginEBIT ÷ Revenue | -5.2% | -414.2% |
| Net MarginNet income ÷ Revenue | -4.9% | -415.2% |
| FCF MarginFCF ÷ Revenue | -2.8% | -379.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | +4.5% | -56.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +8.6% | -15.3% |
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $103M | $141M |
| Enterprise ValueMkt cap + debt − cash | $88M | $135M |
| Trailing P/EPrice ÷ TTM EPS | -1.33x | -0.57x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 7.40x | 4054.38x |
| Price / BookPrice ÷ Book value/share | 0.35x | 14.80x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
SEER delivers a -29.2% return on equity — every $100 of shareholder capital generates $-29 in annual profit, vs $-80 for CDIO. SEER carries lower financial leverage with a 0.08x debt-to-equity ratio, signaling a more conservative balance sheet compared to CDIO's 0.10x.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -29.2% | -80.4% |
| ROA (TTM)Return on assets | -25.7% | -74.5% |
| ROICReturn on invested capital | -21.3% | -2.2% |
| ROCEReturn on capital employed | -25.9% | -123.0% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.08x | 0.10x |
| Net DebtTotal debt minus cash | -$15M | -$7M |
| Cash & Equiv.Liquid assets | $41M | $8M |
| Total DebtShort + long-term debt | $26M | $969,863 |
| Interest CoverageEBIT ÷ Interest expense | — | -418.04x |
Total Returns (with DRIP)
A $10,000 investment in SEER five years ago would be worth $427 today (with dividends reinvested), compared to $179 for CDIO. Over the past 12 months, SEER leads with a -9.3% total return vs CDIO's -62.1%. The 3-year compound annual growth rate (CAGR) favors SEER at -28.2% vs CDIO's -68.0% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +1.6% | +85.2% |
| 1-Year ReturnPast 12 months | -9.3% | -62.1% |
| 3-Year ReturnCumulative with dividends | -62.9% | -96.7% |
| 5-Year ReturnCumulative with dividends | -95.7% | -98.2% |
| 10-Year ReturnCumulative with dividends | -96.7% | -98.2% |
| CAGR (3Y)Annualised 3-year return | -28.2% | -68.0% |
Risk & Volatility
SEER is the less volatile stock with a 0.52 beta — it tends to amplify market swings less than CDIO's 2.02 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. SEER currently trades 76.8% from its 52-week high vs CDIO's 30.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.52x | 2.02x |
| 52-Week HighHighest price in past year | $2.41 | $17.39 |
| 52-Week LowLowest price in past year | $1.62 | $0.97 |
| % of 52W HighCurrent price vs 52-week peak | +76.8% | +30.2% |
| RSI (14)Momentum oscillator 0–100 | 42.7 | 64.3 |
| Avg Volume (50D)Average daily shares traded | 239K | 3.3M |
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | — |
| Price TargetConsensus 12-month target | — | — |
| # AnalystsCovering analysts | 4 | — |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +11.4% | 0.0% |
Historical Charts
Charts are rendered on first load. Hover for details.
Chart 1Total Return — 5 Years (Rebased to 100)
| Stock | Feb 22 | Mar 26 | Change |
|---|---|---|---|
| Seer, Inc. (SEER) | 100 | 9.96 | -90.0% |
| Cardio Diagnostics … (CDIO) | 100.1 | 1.77 | -98.2% |
Seer, Inc. (SEER) returned -96% over 5 years vs Cardio Diagnostics … (CDIO)'s -98%.
Chart 2Revenue Growth — 10 Years
| Stock | 2018 | 2024 | Change |
|---|---|---|---|
| Seer, Inc. (SEER) | $0.00 | $14M | — |
| Cardio Diagnostics … (CDIO) | $0.00 | $34890.00 | — |
Seer, Inc.'s revenue grew from $0M (2018) to $14M (2024) — a 0.0% CAGR.
Chart 3Net Margin Trend — 10 Years
| Stock | 2019 | 2024 | Change |
|---|---|---|---|
| Seer, Inc. (SEER) | -138.3% | -6.2% | +95.5% |
| Cardio Diagnostics … (CDIO) | -688.6% | -240.3% | +65.1% |
Seer, Inc.'s net margin went from -138% (2019) to -6% (2024).
Chart 4EPS Growth — 10 Years
| Stock | 2018 | 2024 | Change |
|---|---|---|---|
| Seer, Inc. (SEER) | -0.29 | -1.39 | -379.3% |
| Cardio Diagnostics … (CDIO) | -0.06 | -9.3 | -14522.6% |
Seer, Inc.'s EPS grew from $-0.29 (2018) to $-1.39 (2024).
Chart 5Free Cash Flow — 5 Years
Seer, Inc. generated $-50M FCF in 2024 (+7% vs 2021). Cardio Diagnostics Holdings, Inc. generated $-5M FCF in 2024 (-672% vs 2021).
SEER vs CDIO: Frequently Asked Questions
7 questions · data-driven answers · updated daily
01Is SEER or CDIO a better buy right now?
Analysts rate Seer, Inc. (SEER) a "Hold" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — SEER or CDIO?
Over the past 5 years, Seer, Inc. (SEER) delivered a total return of -95.7%, compared to -98.2% for Cardio Diagnostics Holdings, Inc. (CDIO). A $10,000 investment in SEER five years ago would be worth approximately $427 today (assuming dividends reinvested). Over 10 years, the gap is even starker: SEER returned -96.7% versus CDIO's -98.2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — SEER or CDIO?
By beta (market sensitivity over 5 years), Seer, Inc. (SEER) is the lower-risk stock at 0.52β versus Cardio Diagnostics Holdings, Inc.'s 2.02β — meaning CDIO is approximately 288% more volatile than SEER relative to the S&P 500. On balance sheet safety, Seer, Inc. (SEER) carries a lower debt/equity ratio of 8% versus 10% for Cardio Diagnostics Holdings, Inc. — giving it more financial flexibility in a downturn.
04Which has better profit margins — SEER or CDIO?
Seer, Inc. (SEER) is the more profitable company, earning -620.9% net margin versus -240.3% for Cardio Diagnostics Holdings, Inc. — meaning it keeps -620.9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SEER leads at -717.7% versus -239.8% for CDIO. At the gross margin level — before operating expenses — CDIO leads at 100.0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
05Which pays a better dividend — SEER or CDIO?
None of the stocks in this comparison currently pay a material dividend. All are effectively zero-yield and should be held for capital appreciation rather than income.
06Is SEER or CDIO better for a retirement portfolio?
For long-horizon retirement investors, Seer, Inc. (SEER) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.52)). Cardio Diagnostics Holdings, Inc. (CDIO) carries a higher beta of 2.02 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SEER: -96.7%, CDIO: -98.2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
07What are the main differences between SEER and CDIO?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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