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CDIOCardio Diagnostics Holdings, Inc.
$2.08$4M
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CDIO logoCardio Diagnostics Holdings, Inc.(CDIO)Earnings, Financials & Key Ratios

CDIO•NASDAQ
$2.08
Price updated Jun 30, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDiagnostics and Omics Tools
AboutCardio Diagnostics Holdings, Inc. develops and commercializes epigenetics-based clinical tests for cardiovascular disease. It offers Epi+Gen CHD, a three-year symptomatic coronary heart disease risk assessment test. Cardio Diagnostics Holdings, Inc. was founded in 2017 and is based in Chicago, Illinois.Show more
  • Revenue$15K-57.5%
  • EBITDA-$6M+24.8%
  • Net Income-$6M+22.5%
  • EPS (Diluted)-3.71+60.1%
  • Gross Margin100%
  • EBITDA Margin-41051.94%-77.1%
  • Operating Margin-43737.46%-82.4%
  • Net Margin-43832.49%-82.4%
  • ROE-78.62%+41.3%

CDIO Price & Volume

Cardio Diagnostics Holdings, Inc. (CDIO) stock price & volume — 10-year historical chart

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Persistent Operational Losses Challenge Commercial Diagnostic Scalability

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Capital exhaustion and dilution

Key Thesis Takeaways

  • Cardio Diagnostics faces a critical juncture as its Epi+Gen CHD diagnostic platform struggles to achieve meaningful market penetration, evidenced by quarterly revenue that remains negligible at $2.7K in 2026Q1.
  • While the company maintains a lean debt-to-equity ratio of 0.06, the persistent operational cash burn and reliance on capital infusions to sustain its $1.7M quarterly SG&A burden present significant long-term solvency risks.
  • Investors should monitor whether the firm's proprietary epigenetic data can eventually command strategic value, as current financial performance suggests an inability to reach a self-sustaining commercial model.

Verdict Logic

the company's inability to generate meaningful revenue, coupled with a persistent quarterly cash burn of $1.6 million, suggests a high risk of continued shareholder dilution and capital exhaustion.

CDIO Growth Metrics

Cardio Diagnostics Holdings, Inc. (CDIO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years149.89%
TTM-16.77%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-13.6%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-16.87%

Return on Capital

10 Years-278.32%
5 Years-132.16%
3 Years-127.15%
Last Year-75.64%

CDIO Recent Earnings

Cardio Diagnostics Holdings, Inc. (CDIO) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (82%)●Beat Revenue 1/12 qtrs (10%)
Q2 2026Latest
May 15, 2026
Metric
Actual
Est
EPS
$0.63
—
Rev
$2,680
—
Q2 2026
Mar 13, 2026
Metric
Actual
Est
EPS
$0.80+55.6%
$1.80
Rev
$3,555-98.6%
$250,000
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.98+45.6%
$1.80
Rev
$2,855-98.1%
$150,000
Q3 2025
Aug 14, 2025
Metric
Actual
Est
EPS
$0.97+46.1%
$1.80
Rev
$7,475-90.0%
$75,000
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 15, 2026
$0.63
$2,680
Q2 2026Mar 13, 2026
$0.80vs $1.80+55.6%
$3,555vs $250,000-98.6%
Q4 2025Nov 12, 2025
$0.98vs $1.80+45.6%
$2,855vs $150,000-98.1%
Q3 2025Aug 14, 2025
$0.97vs $1.80+46.1%
$7,475vs $75,000-90.0%
Based on last 12 quarters of dataView full earnings history →

Latest CDIO News

Recent stock market news and headlines for Cardio Diagnostics Holdings, Inc. (CDIO)

Business Wire·5 days ago
Atlas Healthcare Physicians to Cover Cardio Diagnostics' Precision Cardiovascular Medicine Tests Across Its Network

CHICAGO--(BUSINESS WIRE)--Cardio Diagnostics today announced that Atlas Healthcare Physicians (AHP) will cover Cardio Diagnostics' tests, Epi+Gen CHD™ and PrecisionCHD™.

Peers Comparison

Key metrics vs top competitors for Cardio Diagnostics Holdings, Inc. (CDIO)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CDIO logoCDIOCardio Diagnostics Holdings, Inc.Current
$2.08$4.31M-0.56-57.51%-43832.49%-78.62%—
HLIO logoHLIOHelios Technologies, Inc.
$89.40$2.95B61.664.11%6.98%6.59%—
EXAS logoEXASExact Sciences Corporation
$104.91$20.02B-95.3717.69%-6.4%-8.66%—
NTRA logoNTRANatera, Inc.
$272.31$39B-179.1535.9%-9.05%-15.13%—
TMDX logoTMDXTransMedics Group, Inc.
$67.29$2.33B13.8237.13%27.04%41.92%—
HOLX logoHOLXHologic, Inc.
$76.01$16.97B30.531.74%13.18%11.01%—

Compare CDIO vs Peers

Cardio Diagnostics Holdings, Inc. (CDIO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs HLIO

Most directly comparable listed peer for CDIO.

Scale Benchmark

vs TMO

Larger-name benchmark to compare CDIO against a more recognizable public peer.

Peer Set

Compare Top 5

vs HLIO, EXAS, NTRA, TMDX

CDIO SEC Filings & Documents

Cardio Diagnostics Holdings, Inc. (CDIO) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Feb 19, 2026·SEC

Material company update

Oct 15, 2025·SEC

Material company update

May 28, 2025·SEC

10-K Annual Reports

4
FY 2026

Mar 13, 2026·SEC

FY 2025

Mar 20, 2025·SEC

FY 2024

Apr 1, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 15, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 14, 2025·SEC

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CDIO Frequently Asked Questions

Cardio Diagnostics Holdings, Inc. (CDIO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Cardio Diagnostics Holdings, Inc.'s revenue?

Cardio Diagnostics Holdings, Inc. (CDIO) reported $0.0M in revenue for fiscal year 2025.

How fast is Cardio Diagnostics Holdings, Inc. growing?

Cardio Diagnostics Holdings, Inc. (CDIO) saw revenue decline by 57.5% over the past year.

Is CDIO profitable?

Cardio Diagnostics Holdings, Inc. (CDIO) reported a net loss of $6.7M for fiscal year 2025.

Dividend & Returns
What is CDIO's return on equity?

Cardio Diagnostics Holdings, Inc. (CDIO) has a return on equity (ROE) of -78.6%. Negative ROE indicates the company is unprofitable.

What is Cardio Diagnostics Holdings, Inc.'s free cash flow?

Cardio Diagnostics Holdings, Inc. (CDIO) had negative free cash flow of $6.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CDIO back in 2020?

Total return calculator · dividends reinvested · 6+ years of data

See returns →