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AGEN logoAgenus Inc.(AGEN)Earnings, Financials & Key Ratios

AGEN•NASDAQ
$3.89
$137M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutAgenus Inc., a clinical-stage immuno-oncology company, discovers and develops immuno-oncology products in the United States and internationally. The company offers Retrocyte Display, an antibody expression platform for the identification of fully human and humanized monoclonal antibodies; and display technologies. It develops vaccine programs comprising Prophage vaccine candidate; and QS-21 Stimulon adjuvant, a saponin-based vaccine adjuvant. The company also develops Balstilimab, an anti-PD-1 antagonist that has completed Phase II clinical trial to treat second line cervical cancer; AGEN1181, an anti-CTLA-4 monospecific antibody that is in Phase 1/2 clinical trial; AGEN2373, an anti-CD137 monospecific antibody that is in Phase 1 clinical trial; AGEN1423, a tumor microenvironment conditioning anti-CD73/TGFß TRAP bi-functional antibody that has completed Phase 1 clinical trial; AGEN1777, an anti-TIGIT bispecific antibodies; and AGEN1327, a human monoclonal antibody. In addition, the company develops INCAGN1876, an anti-GITR monospecific antibody; INCAGN1949, an anti-OX40 monospecific antibody; INCAGN2390, an anti-TIM-3 monospecific antibody; INCAGN2385, an anti-LAG-3 monospecific antibody; MK-4830, a monospecific antibody targeting ILT4; AGENT 797, an iNKT cells that is in Phase 1 clinical trial for solid tumors, multiple myeloma, and viral ARDS, as well as in clinical stage to treat hematological malignancies and multiple myeloma/B cells; and AGEN1884, a first-generation anti-CTLA-4 monospecific antibody. Agenus Inc. operates under ASV, Agenus, AutoSynVax, EVAMPLIX, MiNK, PSV, PhosPhoSynVax, Prophage, Retrocyte Display, and Stimulon trademarks. It has collaborations with Incyte Corporation, Merck Sharpe & Dohme, Recepta Biopharma SA, and Gilead Sciences, Inc. The company was formerly known as Antigenics Inc. and changed its name to Agenus Inc. in January 2011. Agenus Inc. was founded in 1994 and is headquartered in Lexington, Massachusetts.Show more
  • Revenue$114M+10.4%
  • EBITDA-$11M+90.1%
  • Net Income$115K+100.1%
  • EPS (Diluted)-0.00+100.0%
  • Gross Margin90.35%+277.9%
  • EBITDA Margin-9.24%+91.1%
  • Operating Margin-18%+84.5%
  • Net Margin0.1%+100.0%
  • Interest Coverage-0.37+63.9%
Technical→

AGEN Key Insights

Agenus Inc. (AGEN) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 38.5% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

AGEN Price & Volume

Agenus Inc. (AGEN) stock price & volume — 10-year historical chart

Loading chart...

AGEN Growth Metrics

Agenus Inc. (AGEN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years16.49%
5 Years5.31%
3 Years5.22%
TTM10.37%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM100.05%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM96.37%

Return on Capital

10 Years-135.82%
5 Years-137.56%
3 Years-248.03%
Last Year-

AGEN Recent Earnings

Agenus Inc. (AGEN) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 6/12 qtrs (50%)
Q2 2026Latest
Mar 16, 2026
EPS
$0.56
Est $1.27
+144.1%
Revenue
$34M
Est $28M
+21.7%
Q4 2025
Nov 10, 2025
EPS
$1.94
Est $2.63
-26.2%
Revenue
$30M
Est $28M
+7.6%
Q3 2025
Aug 11, 2025
EPS
$1.00
Est $0.78
-28.2%
Revenue
$26M
Est $25M
+2.8%
Q2 2025
May 12, 2025
EPS
$1.03
Est $1.61
+36.0%
Revenue
$24M
Est $22M
+8.9%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 16, 2026
$0.56vs $1.27+144.1%
$34Mvs $28M+21.7%
Q4 2025Nov 10, 2025
$1.94vs $2.63-26.2%
$30Mvs $28M+7.6%
Q3 2025Aug 11, 2025
$1.00vs $0.78-28.2%
$26Mvs $25M+2.8%
Q2 2025May 12, 2025
$1.03vs $1.61+36.0%
$24Mvs $22M+8.9%
Based on last 12 quarters of dataView full earnings history →

AGEN Peer Comparison

Agenus Inc. (AGEN) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.67B85.09-8.75-43.89%-192.87%-356.81%0.95
INCY logoINCYIncyte CorporationDirect Competitor19.95B99.8515.5821.22%26.71%29.31%0.01
EXEL logoEXELExelixis, Inc.Direct Competitor12.37B48.7017.526.98%35.08%40.21%0.08
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.62B26.00-7.90-4.26%-156.36%-68.97%0.16
MGNX logoMGNXMacroGenics, Inc.Product Competitor190.59M3.01-2.550.78%-49.91%-120.2%0.66
ALKS logoALKSAlkermes plcProduct Competitor5.89B35.3224.70-5.25%9.78%8.82%0.04
FATE logoFATEFate Therapeutics, Inc.Product Competitor264.17M2.29-1.99-51.24%-20.51%-65.79%0.38
IMVT logoIMVTImmunovant, Inc.Product Competitor5.83B28.67-10.50-47.07%0.00

Compare AGEN vs Peers

Agenus Inc. (AGEN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NKTR

Most directly comparable listed peer for AGEN.

Scale Benchmark

vs AZN

Larger-name benchmark to compare AGEN against a more recognizable public peer.

Peer Set

Compare Top 5

vs NKTR, INCY, EXEL, RCUS

AGEN Income Statement

Agenus Inc. (AGEN) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue42.88M36.78M150.05M88.17M295.67M98.02M156.31M103.46M114.2M
Revenue Growth %89.95%-14.21%307.92%-41.24%235.34%-66.85%59.47%-33.81%10.37%
Cost of Goods Sold116.13M124.6M168.34M144.97M182.08M197.26M237.68M156.01M11.02M
COGS % of Revenue270.83%338.74%112.19%164.42%61.58%201.24%152.05%150.79%9.65%
Gross Profit
-73.25M▲ 0%
-87.82M▼ 19.9%
-18.29M▲ 79.2%
-56.8M▼ 210.5%
113.59M▲ 300.0%
-99.23M▼ 187.4%
-81.37M▲ 18.0%
-52.55M▲ 35.4%
103.17M▲ 296.3%
Gross Margin %-170.83%-238.74%-12.19%-64.42%38.42%-101.24%-52.05%-50.79%90.35%
Gross Profit Growth %-1.17%-19.89%79.17%-210.51%299.99%-187.36%18.01%35.41%296.33%
Operating Expenses33.74M37.34M51.85M60.44M87.84M80.19M78.18M67.92M123.73M
OpEx % of Revenue78.69%101.51%34.55%68.55%29.71%81.81%50.02%65.65%108.35%
Selling, General & Admin33.74M37.34M46.04M59.22M76.36M81.01M78.74M71.88M44.39M
SG&A % of Revenue78.69%101.51%30.68%67.16%25.83%82.64%50.37%69.47%38.87%
Research & Development116.13M124.6M168.34M142.62M178.61M0234.57M155.53M79.34M
R&D % of Revenue270.83%338.74%112.19%161.75%60.41%-150.06%150.32%69.48%
Other Operating Expenses-16.89M-2.18M-162.53M-141.4M-167.13M-815K-235.13M-159.48M0
Operating Income
-103.8M▲ 0%
-123.82M▼ 19.3%
-70.14M▲ 43.4%
-117.23M▼ 67.2%
25.75M▲ 122.0%
-179.43M▼ 796.9%
-159.55M▲ 11.1%
-120.47M▲ 24.5%
-20.56M▲ 82.9%
Operating Margin %-242.09%-336.62%-46.74%-132.96%8.71%-183.04%-102.07%-116.44%-18%
Operating Income Growth %3.42%-19.29%43.36%-67.15%121.96%-796.89%11.08%24.49%82.94%
EBITDA-97.79M-117.53M-63.48M-110.06M32.53M-172.48M-145.96M-107.13M-10.56M
EBITDA Margin %-228.08%-319.53%-42.3%-124.82%11%-175.96%-93.38%-103.55%-9.24%
EBITDA Growth %4.62%-20.18%45.99%-73.38%129.56%-630.14%15.38%26.6%90.15%
D&A (Non-Cash Add-back)6.01M6.29M6.66M7.18M6.79M6.95M13.59M13.34M10M
EBIT-101.82M-136.77M-70.11M-121.81M36.99M-168.79M-159.51M-114.64M-20.56M
Net Interest Income-18.87M-25.27M-41.45M-61.08M-65.72M-61.86M-97.92M-117.63M-55.27M
Interest Income00000000345K
Interest Expense18.87M25.27M41.45M61.08M65.72M61.86M97.92M117.63M55.62M
Other Income/Expense-16.89M-38.22M-41.42M-65.66M-54.47M-51.23M-97.89M-111.8M17.47M
Pretax Income
-120.69M▲ 0%
-162.04M▼ 34.3%
-111.56M▲ 31.2%
-182.89M▼ 63.9%
-28.72M▲ 84.3%
-230.66M▼ 703.0%
-257.44M▼ 11.6%
-232.27M▲ 9.8%
-3.08M▲ 98.7%
Pretax Margin %-281.48%-440.53%-74.35%-207.43%-9.71%-235.31%-164.69%-224.5%-2.7%
Income Tax0-12.95M0000000
Effective Tax Rate %0%7.99%0%0%0%0%0%0%0%
Net Income
-120.69M▲ 0%
-159.69M▼ 32.3%
-107.66M▲ 32.6%
-180.91M▼ 68.0%
-23.93M▲ 86.8%
-220.07M▼ 819.8%
-245.76M▼ 11.7%
-227.21M▲ 7.5%
115K▲ 100.1%
Net Margin %-281.48%-434.14%-71.75%-205.19%-8.09%-224.51%-157.22%-219.61%0.1%
Net Income Growth %4.96%-32.31%32.58%-68.05%86.77%-819.81%-11.67%7.55%100.05%
Net Income (Continuing)-120.69M-162.04M-111.56M-182.89M-28.72M-230.66M-257.44M-232.27M-3.08M
Discontinued Operations000000000
Minority Interest0-2.08M-5.98M-7.83M13.47M6.38M11.95M19.96M-6.75M
EPS (Diluted)
-24.53▲ 0%
-28.83▼ 17.5%
-22.10▲ 23.3%
-21.00▲ 5.0%
-2.11▲ 90.0%
-15.64▼ 641.2%
-13.75▲ 12.1%
-10.59▲ 23.0%
-0.00▲ 100.0%
EPS Growth %15.91%-17.53%23.34%4.98%89.95%-641.23%12.08%22.98%99.97%
EPS (Basic)-24.53-28.83-22.10-21.00-2.11-15.64-13.75-10.59-0.00
Diluted Shares Outstanding4.92M5.54M6.75M8.63M11.45M14.09M17.89M21.47M29.73M
Basic Shares Outstanding4.92M5.54M6.75M8.63M11.45M14.09M17.89M21.47M29.73M
Dividend Payout Ratio---------

AGEN Balance Sheet

Agenus Inc. (AGEN) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets73.55M74.81M86.54M113.78M331.97M213.12M112.42M45.57M133.44M
Cash & Short-Term Investments60.19M53.05M61.81M99.87M306.92M193.36M76.11M40.44M3M
Cash Only60.19M53.05M61.81M99.87M291.93M178.67M76.11M40.44M3M
Short-Term Investments000014.99M14.68M000
Accounts Receivable1.13M938.14K16.29M1.16M1.52M2.74M25.84M407K1.83M
Days Sales Outstanding9.669.3139.634.791.8710.2160.331.445.85
Inventory79.49K55.49K7.42M020.36M13.83M000
Days Inventory Outstanding0.250.1616.09-40.8225.59---
Other Current Assets1.08M1.5M-6.41M2.01M-17.19M-10.63M2.37M2.42M128.61M
Total Non-Current Assets82.2M61.59M68.8M100.73M133.98M200.43M201.5M180.7M93.36M
Property, Plant & Equipment26.18M25.12M33.69M60.27M91.08M164.29M163.03M147.4M24.25M
Fixed Asset Turnover1.64x1.46x4.45x1.46x3.25x0.60x0.96x0.70x4.71x
Goodwill23.05M22.92M23.19M25.45M24.88M25.47M24.72M24.09M24.09M
Intangible Assets31.76M12.34M10.5M10.89M8.49M6.23M4.41M3.38M3.04M
Long-Term Investments0000003.22M042.73M
Other Non-Current Assets1.21M1.21M1.42M4.12M12.21M7.12M6.11M5.83M-742K
Total Assets
138.4M▲ 0%
136.4M▼ 1.4%
155.34M▲ 13.9%
214.51M▲ 38.1%
465.96M▲ 117.2%
413.56M▼ 11.2%
313.91M▼ 24.1%
226.27M▼ 27.9%
226.8M▲ 0.2%
Asset Turnover0.31x0.27x0.97x0.41x0.63x0.24x0.50x0.46x0.50x
Asset Growth %-11.84%-1.45%13.88%38.1%117.22%-11.25%-24.09%-27.92%0.23%
Total Current Liabilities56.44M68.06M122.21M129.88M156.94M188.95M255.9M221.4M323.49M
Accounts Payable8.09M13.62M13.56M17.02M30.49M40.94M61.45M61.47M82.99M
Days Payables Outstanding25.4239.9129.4142.8461.1175.7594.36143.812.75K
Short-Term Debt20.64M146K646K833K728K575K146K2.7M155.11M
Deferred Revenue (Current)4.48M1.81M29.17M17.19M12.43M12.27M18K31K1.14M
Other Current Liabilities3.22M43.71M48.15M69.88M75.66M101.49M141.21M121.85M84.25M
Current Ratio1.30x1.10x0.71x0.88x2.12x1.13x0.44x0.21x0.41x
Quick Ratio1.30x1.10x0.65x0.88x1.99x1.05x0.44x0.21x0.41x
Cash Conversion Cycle-15.51-30.4426.31--18.42-39.96---
Total Non-Current Liabilities157.78M242.88M264.46M296.13M261.11M279.51M206.4M311.29M10.11M
Long-Term Debt142.39M13.21B13.38M18.88M12.82M12.58M12.77M30.47M10.11M
Capital Lease Obligations0-13.2B8.02M34.06M42.11M63.33M67.23M54.55M10.13M
Deferred Tax Liabilities0182.82M26.92M000000
Other Non-Current Liabilities7.65M-13.15B188.44M214.9M194.97M202.45M125.26M225.13M242K
Total Liabilities214.22M310.95M386.67M426.01M418.05M468.46M462.3M532.7M333.6M
Total Debt163.02M13.36M23.39M55.73M58.29M78.43M93.19M94.87M10.11M
Net Debt102.84M-39.7M-38.41M-44.14M-233.64M-100.25M17.08M54.43M7.11M
Debt / Equity----1.22x----
Debt / EBITDA----1.79x----
Net Debt / EBITDA-----7.18x----
Interest Coverage-5.50x-4.90x-1.69x-1.92x0.39x-2.90x-1.63x-1.02x-0.37x
Total Equity
-75.82M▲ 0%
-174.55M▼ 130.2%
-231.34M▼ 32.5%
-211.5M▲ 8.6%
47.91M▲ 122.7%
-54.9M▼ 214.6%
-148.38M▼ 170.3%
-306.42M▼ 106.5%
-113.55M▲ 62.9%
Equity Growth %-93.77%-130.22%-32.54%8.58%122.65%-214.6%-170.27%-106.51%62.94%
Book Value per Share-15.41-31.51-34.28-24.524.19-3.90-8.29-14.27-3.82
Total Shareholders' Equity-75.82M-172.47M-225.36M-203.67M34.44M-61.28M-160.33M-326.38M-271.11M
Common Stock1.02M1.2M1.38M1.96M2.57M3.06M3.94M236K353K
Retained Earnings-1.03B-1.18B-1.28B-1.47B-1.49B-1.71B-1.96B-2.18B-2.18B
Treasury Stock000000000
Accumulated OCI-2.17M-1.54M-1.32M2.77M1.49M915K-955K-1.4M-439K
Minority Interest0-2.08M-5.98M-7.83M13.47M6.38M11.95M19.96M-6.75M

AGEN Cash Flow Statement

Agenus Inc. (AGEN) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-94.23M-131.09M-18.68M-139.1M10.14M-175.37M-224.2M-158.31M-158.31M
Operating CF Margin %-219.76%-356.39%-12.45%-157.76%3.43%-178.91%-143.43%-153.02%-138.63%
Operating CF Growth %-17.84%-39.13%85.75%-644.55%107.29%-1828.66%-27.84%29.39%0%
Net Income-120.69M-162.04M-111.56M-182.89M-28.72M-230.66M-257.44M-232.27M-232.27M
Depreciation & Amortization6.01M6.29M6.66M7.18M6.79M6.95M13.59M13.34M13.34M
Stock-Based Compensation12.43M7.63M9.89M10.42M19.58M18.34M22.87M17.39M17.39M
Deferred Taxes23.56K10.91M58K000000
Other Non-Cash Items14.49M5.95M17.58M17.25M22.25M5.92M-13.98M10.62M15.89M
Working Capital Changes-6.48M170.05K58.68M8.95M-9.74M24.08M10.76M32.6M27.33M
Change in Receivables10.22M196.35K-15.36M16.19M-394K122K-23.46M25.34M-1.73M
Change in Inventory8.71K24K55K000000
Change in Payables1.65M5.37M-234K2.77M10.82M6.49M21.37M2.01M23.5M
Cash from Investing2.06M-3.59M-4.66M-4.44M-43.15M-33.61M3.4M27K27K
Capital Expenditures-3.12M-3.6M-4.66M-3.47M-33.81M-53.06M-9.95M-576K-576K
CapEx % of Revenue7.28%9.78%3.1%3.93%11.44%54.13%6.37%0.56%0.5%
Acquisitions120K6.19K0-975K0-2.92M000
Investments---------
Other Investing120K6.19K005.66M22M3.36M24K24K
Cash from Financing80.54M128.28M31.32M183.85M225.26M95.83M119.87M122.84M122.84M
Debt Issued (Net)14.52M-162.13M-320K2.96M-1.32M-490K-8.93M9.52M2.35M
Equity Issued (Net)1000K1000K1000K1000K1000K1000K1000K1000K1000K
Dividends Paid000000000
Share Repurchases-527K000-1.65M-3.79M-5.17M0-87K
Other Financing775204.39M1.64M4.47M7.59M898K807K74.5M84.27M
Net Change in Cash
-11.26M▲ 0%
-7.13M▲ 36.7%
8.75M▲ 222.7%
40.7M▲ 364.9%
192.09M▲ 372.0%
-113.26M▼ 159.0%
-101.56M▲ 10.3%
-35.71M▲ 64.8%
-35.71M▲ 0.0%
Free Cash Flow
-97.35M▲ 0%
-134.69M▼ 38.4%
-23.34M▲ 82.7%
-142.56M▼ 510.8%
-23.67M▲ 83.4%
-228.44M▼ 865.1%
-234.16M▼ 2.5%
-158.89M▲ 32.1%
-158.89M▲ 0.0%
FCF Margin %-227.03%-366.17%-15.55%-161.69%-8.01%-233.04%-149.8%-153.57%-139.14%
FCF Growth %-5.26%-38.36%82.67%-510.83%83.4%-865.12%-2.5%32.14%0%
FCF per Share-19.78-24.32-3.46-16.53-2.07-16.22-13.09-7.40-5.34
FCF Conversion (FCF/Net Income)0.78x0.82x0.17x0.77x-0.42x0.80x0.91x0.70x-1376.65x
Interest Paid0001.18M1.15M1.14M3.17M2.28M0
Taxes Paid000000000

AGEN Key Ratios

Agenus Inc. (AGEN) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-803.72%-----49.94%----
Return on Invested Capital (ROIC)-562.55%-369.42%--------
Gross Margin-320.73%-170.83%-238.74%-12.19%-64.42%38.42%-101.24%-52.05%-50.79%90.35%
Net Margin-562.6%-281.48%-434.14%-71.75%-205.19%-8.09%-224.51%-157.22%-219.61%0.1%
Debt / Equity-----1.22x----
Interest Coverage-6.21x-5.50x-4.90x-1.69x-1.92x0.39x-2.90x-1.63x-1.02x-0.37x
FCF Conversion0.63x0.78x0.82x0.17x0.77x-0.42x0.80x0.91x0.70x-1376.65x
Revenue Growth-9.04%89.95%-14.21%307.92%-41.24%235.34%-66.85%59.47%-33.81%10.37%

AGEN SEC Filings & Documents

Agenus Inc. (AGEN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 26, 2026·SEC

Material company update

Mar 16, 2026·SEC

Material company update

Jan 16, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 16, 2026·SEC

FY 2025

Mar 17, 2025·SEC

FY 2024

Mar 14, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 11, 2025·SEC

FY 2025

May 12, 2025·SEC

AGEN Frequently Asked Questions

Agenus Inc. (AGEN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Agenus Inc. (AGEN) reported $114.2M in revenue for fiscal year 2025. This represents a 114096% increase from $0.1M in 1999.

Agenus Inc. (AGEN) grew revenue by 10.4% over the past year. This is steady growth.

Yes, Agenus Inc. (AGEN) is profitable, generating $0.1M in net income for fiscal year 2025 (0.1% net margin).

Dividend & Returns

Agenus Inc. (AGEN) had negative free cash flow of $158.9M in fiscal year 2025, likely due to heavy capital investments.

Explore More AGEN

Agenus Inc. (AGEN) financial analysis — history, returns, DCA and operating performance tools

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Revenue History

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Valuation

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