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Iovance Biotherapeutics, Inc. (IOVA) fundamental analysis — strengths, weaknesses & financial health based on data analysis
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
Iovance Biotherapeutics, Inc. (IOVA) stock price & volume — 10-year historical chart
Iovance Biotherapeutics, Inc. (IOVA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Iovance Biotherapeutics, Inc. (IOVA) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q1 2026Latest | Feb 24, 2026 | $0.18vs $0.22+18.2% | $87Mvs $81M+7.4% |
| Q4 2025 | Nov 6, 2025 | $0.25vs $0.29+13.8% | $67Mvs $82M-17.9% |
| Q3 2025 | Aug 7, 2025 | $0.33vs $0.29-13.8% | $60Mvs $78M-23.5% |
| Q2 2025 | May 8, 2025 | $0.36vs $0.25-44.0% | $49Mvs $82M-40.1% |
Iovance Biotherapeutics, Inc. (IOVA) competitors in Cell and Gene Therapy Developers — business model, growth, and fundamentals comparison
Iovance Biotherapeutics, Inc. (IOVA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Iovance Biotherapeutics, Inc. (IOVA) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 0 | 0 | 0 | 0 | 1.19M | 164.07M | 263.5M |
| Revenue Growth % | - | - | - | - | - | - | - | 13698.99% | 60.6% |
| Cost of Goods Sold | 952K | 956K | 8.12M | 0 | 0 | 0 | 10.76M | 124M | 7.29M |
| COGS % of Revenue | - | - | - | - | - | - | 904.54% | 75.57% | 2.77% |
| Gross Profit | -952K▲ 0% | -956K▼ 0.4% | -8.12M▼ 749.7% | 0▲ 100.0% | 0▲ 0% | 0▲ 0% | -9.57M▲ 0% | 40.08M▲ 518.9% | 256.22M▲ 539.3% |
| Gross Margin % | - | - | - | - | - | - | -804.54% | 24.43% | 97.23% |
| Gross Profit Growth % | 2.66% | -0.42% | -749.69% | 100% | - | - | - | 518.93% | 539.34% |
| Operating Expenses | 92.88M | 128.26M | 206.87M | 261.94M | 342.7M | 398.88M | 450.99M | 435.35M | 659.57M |
| OpEx % of Revenue | - | - | - | - | - | - | 37930.45% | 265.35% | 250.31% |
| Selling, General & Admin | 21.26M | 28.43M | 40.85M | 60.21M | 83.66M | 104.1M | 106.92M | 153.02M | 152.32M |
| SG&A % of Revenue | - | - | - | - | - | - | 8992.09% | 93.26% | 57.81% |
| Research & Development | 71.61M | 99.83M | 166.02M | 201.73M | 259.04M | 294.78M | 344.08M | 282.34M | 300.27M |
| R&D % of Revenue | - | - | - | - | - | - | 28938.35% | 172.08% | 113.95% |
| Other Operating Expenses | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 206.98M |
| Operating Income | -92.88M▲ 0% | -128.26M▼ 38.1% | -206.87M▼ 61.3% | -261.94M▼ 26.6% | -342.7M▼ 30.8% | -398.88M▼ 16.4% | -460.56M▼ 15.5% | -395.28M▲ 14.2% | -403.36M▼ 2.0% |
| Operating Margin % | - | - | - | - | - | - | -38734.99% | -240.92% | -153.08% |
| Operating Income Growth % | -73.15% | -38.09% | -61.29% | -26.62% | -30.83% | -16.39% | -15.46% | 14.17% | -2.04% |
| EBITDA | -91.92M | -127.3M | -198.75M | -260.8M | -328.72M | -377.74M | -427.43M | -351.67M | -367.42M |
| EBITDA Margin % | - | - | - | - | - | - | -35948.86% | -214.34% | -139.44% |
| EBITDA Growth % | -74.56% | -38.48% | -56.12% | -31.22% | -26.05% | -14.91% | -13.15% | 17.72% | -4.48% |
| D&A (Non-Cash Add-back) | 952K | 956K | 8.12M | 1.14M | 13.98M | 21.14M | 33.13M | 43.61M | 35.94M |
| EBIT | -92.06M | -123.58M | -197.56M | -261.94M | -342.7M | -398.88M | -460.56M | -395.28M | -393.05M |
| Net Interest Income | 0 | 0 | 9.32M | 2.36M | 451K | 0 | 13.04M | 20.27M | 0 |
| Interest Income | 813K | 0 | 9.32M | 2.36M | 451K | 2.98M | 13.04M | 20.27M | 0 |
| Interest Expense | 0 | 0 | 0 | 0 | 0 | 2.98M | 0 | 0 | 0 |
| Other Income/Expense | 813K | 4.68M | 9.32M | 2.36M | 451K | 2.98M | 13.04M | 20.27M | 10.31M |
| Pretax Income | -92.06M▲ 0% | -123.58M▼ 34.2% | -197.56M▼ 59.9% | -259.58M▼ 31.4% | -342.25M▼ 31.8% | -395.89M▼ 15.7% | -447.52M▼ 13.0% | -375M▲ 16.2% | -393.05M▼ 4.8% |
| Pretax Margin % | - | - | - | - | - | - | -37638.02% | -228.56% | -149.16% |
| Income Tax | 0 | 0 | 0 | 0 | 0 | 0 | -3.48M | -2.83M | -2.07M |
| Effective Tax Rate % | 0% | 0% | 0% | 0% | 0% | 0% | 0.78% | 0.75% | 0.53% |
| Net Income | -92.06M▲ 0% | -123.58M▼ 34.2% | -197.56M▼ 59.9% | -259.58M▼ 31.4% | -342.25M▼ 31.8% | -395.89M▼ 15.7% | -444.04M▼ 12.2% | -372.18M▲ 16.2% | -390.98M▼ 5.1% |
| Net Margin % | - | - | - | - | - | - | -37345.42% | -226.84% | -148.38% |
| Net Income Growth % | -74.05% | -34.23% | -59.86% | -31.4% | -31.85% | -15.67% | -12.16% | 16.18% | -5.05% |
| Net Income (Continuing) | -92.06M | -123.58M | -197.56M | -259.58M | -342.25M | -395.89M | -444.04M | -372.18M | -390.98M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -1.41▲ 0% | -1.27▲ 9.9% | -1.50▼ 18.1% | -1.88▼ 25.3% | -2.23▼ 18.6% | -2.49▼ 11.7% | -1.89▲ 24.1% | -1.28▲ 32.3% | -1.09▲ 14.8% |
| EPS Growth % | -46.88% | 9.93% | -18.11% | -25.33% | -18.62% | -11.66% | 24.1% | 32.28% | 14.84% |
| EPS (Basic) | -1.41 | -1.27 | -1.50 | -1.88 | -2.23 | -2.49 | -1.89 | -1.28 | -1.09 |
| Diluted Shares Outstanding | 65.24M | 97.28M | 124.34M | 138.3M | 153.41M | 159.26M | 235.13M | 289.88M | 357.35M |
| Basic Shares Outstanding | 65.24M | 97.28M | 124.34M | 138.3M | 153.41M | 159.26M | 235.13M | 289.88M | 357.35M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
Iovance Biotherapeutics, Inc. (IOVA) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 149.29M | 475.37M | 316.49M | 636.1M | 507.96M | 479.12M | 307.85M | 457.02M | 442.69M |
| Cash & Short-Term Investments | 145.37M | 468.52M | 307.08M | 629.44M | 504.41M | 471.85M | 279.87M | 323.78M | 296.98M |
| Cash Only | 145.37M | 82.15M | 13.97M | 67.33M | 78.23M | 231.73M | 114.89M | 115.69M | 163.08M |
| Short-Term Investments | 0 | 386.37M | 293.11M | 562.11M | 426.18M | 240.11M | 164.98M | 208.09M | 133.9M |
| Accounts Receivable | 0 | 0 | 0 | 0 | 0 | 0 | 151K | 69.34M | 82.45M |
| Days Sales Outstanding | - | - | - | - | - | - | 46.35 | 154.26 | 114.21 |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 10.37M | 51.52M | 51.68M |
| Days Inventory Outstanding | - | - | - | - | - | - | 352 | 151.66 | 2.59K |
| Other Current Assets | 3.92M | 6.85M | 0 | 0 | 0 | 7.27M | 17.46M | 12.38M | 11.58M |
| Total Non-Current Assets | 6.08M | 5.45M | 28.16M | 132.36M | 269.38M | 184.87M | 472.5M | 453.41M | 470.48M |
| Property, Plant & Equipment | 2.45M | 2.68M | 19.23M | 113.92M | 169.92M | 178.25M | 176.54M | 164.28M | 177.01M |
| Fixed Asset Turnover | - | - | - | - | - | - | 0.01x | 1.00x | 1.49x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 229.26M | 282.4M | 279.32M |
| Long-Term Investments | 0 | 0 | 0 | 0 | 91.59M | 0 | 66.43M | 0 | 0 |
| Other Non-Current Assets | 3.63M | 2.76M | 8.93M | 18.44M | 7.87M | 6.62M | 270K | 6.73M | 14.15M |
| Total Assets | 155.37M▲ 0% | 480.82M▲ 209.5% | 344.65M▼ 28.3% | 768.46M▲ 123.0% | 777.33M▲ 1.2% | 663.98M▼ 14.6% | 780.35M▲ 17.5% | 910.43M▲ 16.7% | 913.17M▲ 0.3% |
| Asset Turnover | - | - | - | - | - | - | 0.00x | 0.18x | 0.29x |
| Asset Growth % | -9.61% | 209.46% | -28.32% | 122.96% | 1.15% | -14.58% | 17.53% | 16.67% | 0.3% |
| Total Current Liabilities | 9.89M | 14.4M | 39.08M | 54.87M | 89.2M | 91.48M | 110.31M | 122.34M | 138.36M |
| Accounts Payable | 1.23M | 2.74M | 15.57M | 13.51M | 27.38M | 26.6M | 33.12M | 27.51M | 22.16M |
| Days Payables Outstanding | 472.35 | 1.05K | 699.49 | - | - | - | 1.12K | 80.98 | 1.11K |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.04M |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 5.75M | 7.55M | 0 | 0 | 0 | 0 | 34.59M | 50.03M | 112.16M |
| Current Ratio | 15.09x | 33.02x | 8.10x | 11.59x | 5.69x | 5.24x | 2.79x | 3.74x | 3.20x |
| Quick Ratio | 15.09x | 33.02x | 8.10x | 11.59x | 5.69x | 5.24x | 2.70x | 3.31x | 2.83x |
| Cash Conversion Cycle | - | - | - | - | - | - | -725.76 | 224.94 | 1.59K |
| Total Non-Current Liabilities | 297K | 230K | 6.6M | 57.09M | 66.47M | 72.86M | 85.43M | 77.68M | 76.23M |
| Long-Term Debt | 0 | 0 | 0 | 0 | 1M | 1M | 1M | 1M | 44.4M |
| Capital Lease Obligations | 0 | 0 | 4.25M | 45.38M | 65.47M | 71.86M | 67.08M | 44.37M | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 17.35M | 32.31M | 31.83M |
| Other Non-Current Liabilities | 297K | 230K | 2.35M | 11.71M | 0 | 0 | 0 | 0 | 0 |
| Total Liabilities | 9.89M | 14.63M | 45.68M | 111.96M | 155.67M | 164.34M | 195.74M | 200.02M | 214.59M |
| Total Debt | 0 | 0 | 11.5M | 51.66M | 71.53M | 85.45M | 75.86M | 58.26M | 48.44M |
| Net Debt | -145.37M | -82.15M | -2.47M | -15.67M | -6.7M | -146.28M | -39.03M | -57.43M | -114.63M |
| Debt / Equity | - | - | 0.04x | 0.08x | 0.12x | 0.17x | 0.13x | 0.08x | 0.07x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Interest Coverage | - | - | - | - | - | -133.63x | - | - | - |
| Total Equity | 145.48M▲ 0% | 466.19M▲ 220.4% | 298.97M▼ 35.9% | 656.5M▲ 119.6% | 621.66M▼ 5.3% | 499.64M▼ 19.6% | 584.61M▲ 17.0% | 710.4M▲ 21.5% | 698.58M▼ 1.7% |
| Equity Growth % | -12.84% | 220.45% | -35.87% | 119.59% | -5.31% | -19.63% | 17.01% | 21.52% | -1.66% |
| Book Value per Share | 2.23 | 4.79 | 2.40 | 4.75 | 4.05 | 3.14 | 2.49 | 2.45 | 1.95 |
| Total Shareholders' Equity | 145.48M | 466.19M | 298.97M | 656.5M | 621.66M | 499.64M | 584.61M | 710.4M | 698.58M |
| Common Stock | 3K | 5K | 5K | 6K | 7K | 8K | 11K | 13K | 17K |
| Retained Earnings | -249.18M | -372.76M | -570.61M | -830.19M | -1.17B | -1.57B | -2.01B | -2.38B | -2.78B |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | 0 | -42K | 220K | 19K | -601K | -902K | 2.53M | -1.05M | 16.44M |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Iovance Biotherapeutics, Inc. (IOVA) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -78.71M | -101.25M | -158.89M | -205.13M | -227.94M | -292.76M | -361.82M | -352.98M | -302.41M |
| Operating CF Margin % | - | - | - | - | - | - | -30430.61% | -215.14% | -114.77% |
| Operating CF Growth % | -140.94% | -28.64% | -56.93% | -29.11% | -11.12% | -28.44% | -23.59% | 2.44% | 14.33% |
| Net Income | -92.06M | -123.58M | -197.56M | -259.58M | -342.25M | -395.89M | -444.04M | -372.18M | -390.98M |
| Depreciation & Amortization | 952K | 956K | 8.12M | 1.14M | 13.98M | 21.14M | 33.13M | 43.61M | 34.46M |
| Stock-Based Compensation | 11.97M | 20.03M | 24.28M | 40.89M | 69.77M | 84.02M | 62.63M | 109.63M | 61.58M |
| Deferred Taxes | 0 | 0 | 0 | 1.86M | 0 | 0 | -3.48M | -2.83M | -2.07M |
| Other Non-Cash Items | 19K | -1.32M | 8.97M | 7.57M | 6.01M | 871K | -3.54M | -8.65M | 18.87M |
| Working Capital Changes | 416K | 2.67M | -2.7M | 2.98M | 24.55M | -2.89M | -6.52M | -122.56M | -24.27M |
| Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | -149K | -69.19M | -13.11M |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | -10.12M | -39.92M | -14.21M |
| Change in Payables | 369K | 1.51M | 0 | -2.96M | 6.98M | 5.88M | 4.83M | -7.84M | -6.66M |
| Cash from Investing | 58.68M | -386.28M | 90.03M | -317.85M | 132K | 256.45M | -155.24M | -96.41M | 47.5M |
| Capital Expenditures | -1.03M | -1.2M | -6.92M | -46.79M | -37.57M | -20.43M | -22.29M | -11.07M | -33.84M |
| CapEx % of Revenue | - | - | - | - | - | - | 1874.68% | 6.75% | 12.84% |
| Acquisitions | 0 | 0 | 0 | 271.06M | -37.71M | -276.88M | -212.63M | -52.57M | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | 59.7M | -385.08M | 96.94M | -271.06M | 37.71M | 276.88M | 0 | 0 | 0 |
| Cash from Financing | 58.69M | 424.31M | 6.13M | 576.42M | 239.27M | 190.15M | 462.96M | 390.66M | 300.77M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 1M | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 1000K | 1000K | -312K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -1.25M | 0 | -312K | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 5.03M | -373.33M | 6.44M | 9.38M | 35.11M | 648K | -322K | -6.64M | -7.06M |
| Net Change in Cash | 38.66M▲ 0% | -63.22M▼ 263.5% | -62.73M▲ 0.8% | 53.44M▲ 185.2% | 11.46M▼ 78.6% | 153.85M▲ 1242.6% | -56.84M▼ 136.9% | -59.27M▼ 4.3% | 47.38M▲ 180.0% |
| Free Cash Flow | -79.74M▲ 0% | -102.45M▼ 28.5% | -165.81M▼ 61.8% | -251.93M▼ 51.9% | -265.51M▼ 5.4% | -313.18M▼ 18.0% | -384.11M▼ 22.6% | -364.05M▲ 5.2% | -336.24M▲ 7.6% |
| FCF Margin % | - | - | - | - | - | - | -32305.3% | -221.88% | -127.61% |
| FCF Growth % | -133.22% | -28.48% | -61.85% | -51.94% | -5.39% | -17.95% | -22.65% | 5.22% | 7.64% |
| FCF per Share | -1.22 | -1.05 | -1.33 | -1.82 | -1.73 | -1.97 | -1.63 | -1.26 | -0.94 |
| FCF Conversion (FCF/Net Income) | 0.85x | 0.82x | 0.80x | 0.79x | 0.67x | 0.74x | 0.81x | 0.95x | 0.77x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Iovance Biotherapeutics, Inc. (IOVA) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -39.04% | -58.94% | -40.41% | -51.64% | -54.34% | -53.55% | -70.61% | -81.91% | -57.48% | -55.5% |
| Return on Invested Capital (ROIC) | -10435.6% | -25056.74% | -50.08% | -45.6% | -41.92% | -40.93% | -61.79% | -76.85% | -49.47% | -48.91% |
| Gross Margin | - | - | - | - | - | - | - | -804.54% | 24.43% | 97.23% |
| Net Margin | - | - | - | - | - | - | - | -37345.42% | -226.84% | -148.38% |
| Debt / Equity | - | - | - | 0.04x | 0.08x | 0.12x | 0.17x | 0.13x | 0.08x | 0.07x |
| Interest Coverage | - | - | - | - | - | - | -133.63x | - | - | - |
| FCF Conversion | 0.62x | 0.85x | 0.82x | 0.80x | 0.79x | 0.67x | 0.74x | 0.81x | 0.95x | 0.77x |
| Revenue Growth | - | - | - | - | - | - | - | - | 13698.99% | 60.6% |
Iovance Biotherapeutics, Inc. (IOVA) SEC filings — annual & quarterly reports (10-K, 10-Q)
Mar 20, 2026·SEC
Feb 24, 2026·SEC
Jan 9, 2026·SEC
Iovance Biotherapeutics, Inc. (IOVA) stock FAQ — growth, dividends, profitability & financials explained
Iovance Biotherapeutics, Inc. (IOVA) reported $263.5M in revenue for fiscal year 2025.
Iovance Biotherapeutics, Inc. (IOVA) grew revenue by 60.6% over the past year. This is strong growth.
Iovance Biotherapeutics, Inc. (IOVA) reported a net loss of $391.0M for fiscal year 2025.
Iovance Biotherapeutics, Inc. (IOVA) has a return on equity (ROE) of -55.5%. Negative ROE indicates the company is unprofitable.
Iovance Biotherapeutics, Inc. (IOVA) had negative free cash flow of $336.2M in fiscal year 2025, likely due to heavy capital investments.
Iovance Biotherapeutics, Inc. (IOVA) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates