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Aytu BioPharma, Inc. (AYTU) 10-Year Financial Performance & Capital Metrics

AYTU • • Industrial / General
HealthcareSpecialty & Generic PharmaSpecialty PharmaceuticalsCNS & Pain Management
AboutAytu Biopharma, Inc., a specialty pharmaceutical company, focuses on developing and commercializing novel therapeutics and consumer healthcare products the United States and internationally. The company offers Adzenys XR-ODT for the treatment of attention deficit hyperactivity disorder (ADHD) in patients from 6 years and older; Cotempla XR-ODT for the treatment of ADHD in patients from 6 to 17 years old; and Adzenys ER, an oral suspension for the treatment of ADHD in patients from 6 years and older. It also provides Karbinal ER, a carbinoxamine oral suspension for the treatment of seasonal and perennial allergies; Poly-Vi-Flor and Tri-Vi-Flor prescription supplements for infants and children for the treatment of fluoride deficiency; Tuzistra XR, a prescription antitussive consisting of codeine polistirex and chlorpheniramine polistirex in an oral suspension; and ZolpiMist, an oral spray for the treatment of insomnia. The company was formerly known as Aytu BioScience, Inc. and changed its name to Aytu Biopharma, Inc. in March 2021. Aytu Biopharma, Inc. was incorporated in 2015 and is headquartered in Englewood, Colorado.Show more
  • Revenue $66M +1.8%
  • EBITDA -$2M -147.7%
  • Net Income -$14M +14.4%
  • EPS (Diluted) -2.16 +24.5%
  • Gross Margin 69.04% -8.3%
  • EBITDA Margin -3.69% -146.9%
  • Operating Margin -11.79% -383.1%
  • Net Margin -20.43% +15.9%
  • ROE -58.1% -23.0%
  • ROIC -33.47% -894.7%
  • Debt/Equity 1.21 +104.2%
  • Interest Coverage -2.11 -536.6%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 85 (top 15%)
  • ✓Strong 5Y sales CAGR of 19.2%
  • ✓Trading at only 0.9x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Shares diluted 13.4% in last year

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y73.94%
5Y19.16%
3Y-11.78%
TTM-5.39%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-109.14%

EPS CAGR

10Y-
5Y-
3Y-
TTM-147.99%

ROCE

10Y Avg-70.95%
5Y Avg-35.52%
3Y Avg-13.29%
Latest-13.3%

Peer Comparison

CNS & Pain Management
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
NBIXNeurocrine Biosciences, Inc.13.49B135.3341.1324.81%15.95%14.25%4.13%0.18
SUPNSupernus Pharmaceuticals, Inc.2.97B51.8039.248.94%-2.8%-1.82%5.76%0.03
PTPIPetros Pharmaceuticals, Inc.338.98K0.01-0.00-12.2%-9.68%-208.53%
QNTMQuantum BioPharma Ltd.26.94M7.01-0.56-379.78%0.08
AYTUAytu BioPharma, Inc.28.02M2.75-1.271.84%-20.52%-56.41%1.21
AQSTAquestive Therapeutics, Inc.429.45M3.52-6.9013.8%-158.95%
AVDLAvadel Pharmaceuticals plc2.11B21.50-42.165.05%-0.11%-0.28%0.02
RGCRegencell Bioscience Holdings Limited17.39B35.17-4042.53-67.02%0.01

Profit & Loss

Jun 2016Jun 2017Jun 2018Jun 2019Jun 2020Jun 2021Jun 2022Jun 2023Jun 2024Jun 2025
Sales/Revenue+2.56M3.22M3.66M7.32M27.63M65.63M96.67M107.4M65.18M66.38M
Revenue Growth %8.79%0.26%0.14%1%2.77%1.38%0.47%0.11%-0.39%0.02%
Cost of Goods Sold+957.08K1.42M2.05M2.2M8.28M36.43M46.39M40.77M16.13M20.55M
COGS % of Revenue0.37%0.44%0.56%0.3%0.3%0.56%0.48%0.38%0.25%0.31%
Gross Profit+1.61M1.8M1.61M5.12M19.35M29.2M50.28M66.63M49.05M45.83M
Gross Margin %0.63%0.56%0.44%0.7%0.7%0.44%0.52%0.62%0.75%0.69%
Gross Profit Growth %8.24%0.12%-0.11%2.18%2.78%0.51%0.72%0.33%-0.26%-0.07%
Operating Expenses+15.81M20.66M19.45M21.96M40.48M88.07M160.19M83.7M50.65M53.66M
OpEx % of Revenue6.17%6.41%5.32%3%1.47%1.34%1.66%0.78%0.78%0.81%
Selling, General & Admin8.83M17.61M17.73M19.24M31.06M55.81M69.88M70.08M42.04M38.28M
SG&A % of Revenue3.44%5.47%4.84%2.63%1.12%0.85%0.72%0.65%0.64%0.58%
Research & Development6.32M1.35M167.59K589.07K1.72M5.62M12.66M4.09M2.77M1.33M
R&D % of Revenue2.47%0.42%0.05%0.08%0.06%0.09%0.13%0.04%0.04%0.02%
Other Operating Expenses664.71K1.71M6.28M2.14M7.7M26.64M77.65M9.52M5.84M14.05M
Operating Income+-21.7M-20.13M-19.7M-16.85M-21.13M-58.87M-109.91M-17.07M-1.59M-7.83M
Operating Margin %-8.47%-6.25%-5.38%-2.3%-0.76%-0.9%-1.14%-0.16%-0.02%-0.12%
Operating Income Growth %-1.84%0.07%0.02%0.14%-0.25%-1.79%-0.87%0.84%0.91%-3.92%
EBITDA+-20.83M-18.28M-17.85M-14.61M-15.42M-49.67M-99.76M-8.25M5.13M-2.45M
EBITDA Margin %-8.13%-5.67%-4.88%-2%-0.56%-0.76%-1.03%-0.08%0.08%-0.04%
EBITDA Growth %-1.77%0.12%0.02%0.18%-0.06%-2.22%-1.01%0.92%1.62%-1.48%
D&A (Non-Cash Add-back)874.79K1.84M1.85M2.24M5.71M9.2M10.15M8.81M6.72M5.38M
EBIT-22.69M-19.97M-17.84M-16.85M-17.92M-38.24M-38.1M-12.09M-5.32M-10.04M
Net Interest Income+-5.49M-2.53M-749.42K000-147.48M-4.96M-4.79M-3.7M
Interest Income00000014K000
Interest Expense5.49M2.53M749.42K000147.5M4.96M4.79M3.7M
Other Income/Expense-6.48M-2.38M9.51M-10.29M7.51M840K1.02M14K-8.79M-5.92M
Pretax Income+-28.18M-22.51M-10.19M-27.13M-13.62M-58.03M-108.89M-17.05M-10.38M-13.74M
Pretax Margin %-11%-6.99%-2.78%-3.71%-0.49%-0.88%-1.13%-0.16%-0.16%-0.21%
Income Tax+00020.04M0259K-110K02.14M437K
Effective Tax Rate %1%1%1%1.74%1%1%1%1%1.53%0.99%
Net Income+-28.18M-22.51M-10.19M-47.17M-13.62M-58.29M-108.78M-17.05M-15.84M-13.56M
Net Margin %-11%-6.99%-2.78%-6.44%-0.49%-0.89%-1.13%-0.16%-0.24%-0.2%
Net Income Growth %-2.65%0.2%0.55%-3.63%0.71%-3.28%-0.87%0.84%0.07%0.14%
Net Income (Continuing)-28.18M-22.51M-10.19M-27.13M-13.62M-58.29M-108.78M-17.05M-12.52M-14.18M
Discontinued Operations00000000-3.32M620K
Minority Interest0000000000
EPS (Diluted)+-999999.00-193194.38-3061.23-1210.28-60.20-69.60-74.01-5.11-2.86-2.16
EPS Growth %-1.35%0.85%0.98%0.6%0.95%-0.16%-0.06%0.93%0.44%0.24%
EPS (Basic)-999999.00-193194.38-3061.23-1210.28-60.20-69.60-74.01-5.11-2.86-2.16
Diluted Shares Outstanding221173.33K38.97K230K840K1.47M3.34M5.54M6.28M
Basic Shares Outstanding221173.33K38.97K230K840K1.47M3.34M5.54M6.28M
Dividend Payout Ratio----------

Balance Sheet

Jun 2016Jun 2017Jun 2018Jun 2019Jun 2020Jun 2021Jun 2022Jun 2023Jun 2024Jun 2025
Total Current Assets+10.12M3.03M9.47M15.43M75.42M105.23M59.93M72.83M61.89M79.18M
Cash & Short-Term Investments9.1M802.33K7.01M11.04M48.08M49.65M19.36M22.98M20.01M30.95M
Cash Only8.05M802.33K7.01M11.04M48.08M49.65M19.36M22.98M20.01M30.95M
Short-Term Investments1.04M000000000
Accounts Receivable162.43K528.04K578.78K1.74M5.63M28.18M21.71M28.94M23.53M31.16M
Days Sales Outstanding23.1459.8357.7286.874.41156.781.9898.34131.74171.31
Inventory524.71K1.31M1.34M1.44M10M16.34M10.85M11.99M12.14M11.43M
Days Inventory Outstanding200.11337.93238.34238.7440.72163.6985.37107.4274.75203.08
Other Current Assets121.98K75.21K100K250K5.99M1.29M633K868K1.12M0
Total Non-Current Assets+14.22M11.97M11.59M19.29M77.87M160.43M77.69M65.01M56.97M45M
Property, Plant & Equipment231.43K647.25K219K203.73K893K8.7M6.3M3.87M1.52M1.59M
Fixed Asset Turnover11.07x4.98x16.71x35.93x30.94x7.54x15.35x27.76x42.83x41.67x
Goodwill221K238.43K0028.09M65.8M0000
Intangible Assets13.55M11.08M11.37M19.08M48.85M85.46M70.63M58.97M52.45M42.2M
Long-Term Investments00000-10.91M0000
Other Non-Current Assets216.36K2.89K4.72K2.2K33K465K766K792K2.23M1.2M
Total Assets+24.34M15M21.06M34.72M153.29M265.67M137.62M137.84M118.86M124.18M
Asset Turnover0.11x0.21x0.17x0.21x0.18x0.25x0.70x0.78x0.55x0.53x
Asset Growth %0.34%-0.38%0.4%0.65%3.41%0.73%-0.48%0%-0.14%0.04%
Total Current Liabilities+10.1M3.61M3.39M5.37M28.76M109.44M64.44M69.02M62.23M63.06M
Accounts Payable2.32M2.22M2.12M2.13M11.64M19.25M10.99M13.48M10.31M10.6M
Days Payables Outstanding885.77571.8377.3353.64513.05192.9186.45120.67233.41188.28
Short-Term Debt0000982K24.6M3.81M8.74M4.96M10.92M
Deferred Revenue (Current)0000339.34K1000K0000
Other Current Liabilities6.58M1.05M734.43K2.23M8M1.47M23.84M41.12M42.35M26.14M
Current Ratio1.00x0.84x2.79x2.87x2.62x0.96x0.93x1.06x0.99x1.26x
Quick Ratio0.95x0.48x2.40x2.60x2.27x0.81x0.76x0.88x0.80x1.07x
Cash Conversion Cycle-662.53-174.05-81.25-28.152.08127.4880.8985.07173.08186.1
Total Non-Current Liabilities+4.15M7.39M4.24M22.26M29.52M18.66M28.87M29.47M28.91M42.15M
Long-Term Debt000002.8M14.2M20.86M10.88M10.89M
Capital Lease Obligations0000725K2.62M84K832K577K985K
Deferred Tax Liabilities0000011.15M01.38M762K0
Other Non-Current Liabilities4.15M7.39M4.24M22.26M28.79M13.23M14.59M6.4M16.7M30.27M
Total Liabilities14.26M11M7.64M27.63M58.28M128.1M93.31M98.48M91.14M105.21M
Total Debt+00002.01M30.97M18.19M30.43M16.42M22.94M
Net Debt-8.05M-802.33K-7.01M-11.04M-46.08M-18.68M-1.17M7.44M-3.59M-8.02M
Debt / Equity----0.02x0.23x0.41x0.77x0.59x1.21x
Debt / EBITDA--------3.20x-
Net Debt / EBITDA---------0.70x-
Interest Coverage-3.95x-7.94x-26.29x----0.75x-3.44x-0.33x-2.11x
Total Equity+10.09M4M13.42M7.09M95.02M137.57M44.31M39.36M27.72M18.97M
Equity Growth %-0.35%-0.6%2.36%-0.47%12.41%0.45%-0.68%-0.11%-0.3%-0.32%
Book Value per Share463368.5234331.424033.78181.87413.11163.7730.1411.785.003.02
Total Shareholders' Equity10.09M4M13.42M7.09M95.02M137.57M44.31M39.36M27.72M18.97M
Common Stock374821791.75K1K3K01K1K1K
Retained Earnings-46.56M-69.07M-79.26M-106.39M-120.01M-178.3M-287.08M-304.13M-319.97M-333.54M
Treasury Stock0000000000
Accumulated OCI-112K-246K00000000
Minority Interest0000000000

Cash Flow

Jun 2016Jun 2017Jun 2018Jun 2019Jun 2020Jun 2021Jun 2022Jun 2023Jun 2024Jun 2025
Cash from Operations+-10.66M-13.83M-15.94M-13.83M-28.37M-25.96M-28.82M-5.13M-1.39M-1.94M
Operating CF Margin %-4.16%-4.29%-4.36%-1.89%-1.03%-0.4%-0.3%-0.05%-0.02%-0.03%
Operating CF Growth %-0.61%-0.3%-0.15%0.13%-1.05%0.08%-0.11%0.82%0.73%-0.4%
Net Income-28.18M-22.51M-10.19M-27.13M-13.62M-58.29M-108.78M-17.05M-15.84M-13.56M
Depreciation & Amortization874.79K4.36M2.59M2.73M6.25M9.2M10.15M8.81M6.72M5.38M
Stock-Based Compensation902.95K2.5M348.51K1.02M1.08M3.57M5.25M6.05M2.37M576K
Deferred Taxes13.55M1.62M-1.94M-80.78K573.53K00000
Other Non-Cash Items403.78K1.23M-6.03M9.84M-10.04M17.87M75.42M2.86M10.02M11.4M
Working Capital Changes1.79M-1.04M-718.81K-210.2K-12.61M1.68M-10.86M-5.8M-4.66M-5.73M
Change in Receivables-5.37K-355.03K-50.74K-1.16M-3.56M1.54M6.53M-7.15M5.2M-7.63M
Change in Inventory-485.26K195.43K-26.75K-101.1K-6.95M2.79M1.3M-3.61M-4.82M382K
Change in Payables1.62M493.22K-109.71K134.78K-1.38M-3.25M-7.68M2.38M-2.08M287K
Cash from Investing+-5.3M-3.53M-484.29K-1.06M-5.66M-2.78M-3.25M-117K-329K-2.56M
Capital Expenditures-2.25M-111.61K-74.71K-59.85K0000-329K-228K
CapEx % of Revenue0.88%0.03%0.02%0.01%----0.01%0%
Acquisitions----------
Investments----------
Other Investing2K613.31K-402.2K-497.11K-5.84M-2.3M-70K-112K0-2.33M
Cash from Financing+16.66M10.19M22.66M19.08M71.07M30.31M1.53M8.87M-1.26M15.44M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing-1.23M845.19K-2.08M14.08M-44.14M-6.09M-4.94M-4.36M-2.84M-6.07M
Net Change in Cash----------
Free Cash Flow+-12.91M-13.94M-16.02M-13.89M-28.37M-25.96M-28.82M-5.13M-1.72M-5.17M
FCF Margin %-5.04%-4.33%-4.38%-1.9%-1.03%-0.4%-0.3%-0.05%-0.03%-0.08%
FCF Growth %-0.95%-0.08%-0.15%0.13%-1.04%0.08%-0.11%0.82%0.67%-2.01%
FCF per Share-593169.47-119661.30-4812.17-356.44-123.36-30.91-19.61-1.54-0.31-0.82
FCF Conversion (FCF/Net Income)0.38x0.61x1.56x0.29x2.08x0.45x0.26x0.30x0.09x0.14x
Interest Paid000001.25M3.15M3.81M4.04M2.82M
Taxes Paid000000001.61M1.42M

Key Ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-219.29%-319.61%-116.94%-459.89%-26.68%-50.12%-119.62%-40.76%-47.24%-58.1%
Return on Invested Capital (ROIC)-316.25%-577.37%-307.51%-1029.09%-70.46%-52.62%-101.75%-28.46%-3.36%-33.47%
Gross Margin62.65%56%43.97%69.92%70.03%44.49%52.02%62.04%75.26%69.04%
Net Margin-1099.73%-698.67%-278.36%-644.33%-49.29%-88.81%-112.53%-15.88%-24.31%-20.43%
Debt / Equity----0.02x0.23x0.41x0.77x0.59x1.21x
Interest Coverage-3.95x-7.94x-26.29x----0.75x-3.44x-0.33x-2.11x
FCF Conversion0.38x0.61x1.56x0.29x2.08x0.45x0.26x0.30x0.09x0.14x
Revenue Growth878.85%25.72%13.61%100.01%277.47%137.52%47.29%11.1%-39.31%1.84%

Revenue by Segment

2015201720202021202220232024
Consumer Health-----33.6M15.82M
Consumer Health Growth-------52.92%
Consumer Health Portfolio----35.55M--
Consumer Health Portfolio Growth-------
Pediatric Portfolio----16.08M--
Pediatric Portfolio Growth-------
Aytu Consumer Health---32.95M---
Aytu Consumer Health Growth-------
Aytu Bio Pharma---32.68M---
Aytu Bio Pharma Growth-------
Product Revenue--27.63M----
Product Revenue Growth-------
License Revenue-------
License Revenue Growth-------
AYTU Bioscience, Inc.-3.17M-----
AYTU Bioscience, Inc. Growth-------
Aytu Women's Health-47K-----
Aytu Women's Health Growth-------

Revenue by Geography

2015201720202021202220232024
UNITED STATES----94.61M106.92M80.91M
UNITED STATES Growth-----13.01%-24.32%
Non-US----2.06M481K91K
Non-US Growth------76.68%-81.08%
Non Us---4.95M---
Non Us Growth-------
KOREA, REPUBLIC OF500K------
KOREA, REPUBLIC OF Growth-------

Frequently Asked Questions

Growth & Financials

Aytu BioPharma, Inc. (AYTU) reported $63.7M in revenue for fiscal year 2025. This represents a 3639671% increase from $0.0M in 2012.

Aytu BioPharma, Inc. (AYTU) grew revenue by 1.8% over the past year. Growth has been modest.

Aytu BioPharma, Inc. (AYTU) reported a net loss of $13.1M for fiscal year 2025.

Dividend & Returns

Aytu BioPharma, Inc. (AYTU) has a return on equity (ROE) of -58.1%. Negative ROE indicates the company is unprofitable.

Aytu BioPharma, Inc. (AYTU) had negative free cash flow of $1.5M in fiscal year 2025, likely due to heavy capital investments.

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