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Caribou Biosciences, Inc. (CRBU) 10-Year Financial Performance & Capital Metrics

CRBU • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsImmuno-Oncology
AboutCaribou Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of genome-edited allogeneic cell therapies for the treatment of hematologic malignancies and solid tumors in the United States and internationally. Its lead product candidates are CB-010, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy for the treatment of relapsed or refractory multiple myeloma. The company also develops CB-012, an allogeneic anti-CD371 CAR-T cell therapy for the treatment of relapsed or refractory acute myeloid leukemia; and CB-020, an allogeneic CAR-NK cell therapy for the treatment of solid tumors. It has collaboration with AbbVie Manufacturing Management Unlimited Company to develop CAR-T cell therapies. The company was incorporated in 2011 and is headquartered in Berkeley, California.Show more
  • Revenue $10M -71.0%
  • EBITDA -$163M -44.6%
  • Net Income -$149M -46.1%
  • EPS (Diluted) -1.65 -19.6%
  • Gross Margin 60.71% -32.4%
  • EBITDA Margin -1627.87% -398.7%
  • Operating Margin -1667.16% -395.3%
  • Net Margin -1491.95% -403.9%
  • ROE -47.99% -57.3%
  • ROIC -41.14% -45.2%
  • Debt/Equity 0.10 +42.3%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 11.5%
  • ✓Trading at only 0.6x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Negative free cash flow
  • ✗Shares diluted 22.4% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y11.54%
3Y1.36%
TTM-19%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-6.08%

EPS CAGR

10Y-
5Y-
3Y-
TTM-3.03%

ROCE

10Y Avg-49.95%
5Y Avg-46.71%
3Y Avg-35.81%
Latest-48.54%

Peer Comparison

Immuno-Oncology
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
IMTXImmatics N.V.1.33B9.9270.86188.6%-136.72%-27.81%0.03
CTMXCytomX Therapeutics, Inc.720.1M4.2511.1836.45%24.66%26.09%
IOVAIovance Biotherapeutics, Inc.881.27M2.22-1.73136.99%-158.78%-56.62%0.08
REPLReplimune Group, Inc.572.64M7.30-2.38-117.82%0.18
NKTRNektar Therapeutics719.28M35.36-4.079.22%-192.87%-141.9%1.69
IMNMImmunome, Inc.2.52B22.85-4.57-35.5%-23.01%-84.4%0.03
IBRXImmunityBio, Inc.3.89B3.95-6.3722.71%-422.28%
NRIXNurix Therapeutics, Inc.1.91B18.86-6.55-29.15%-292.5%-65.76%0.05

Profit & Loss

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+5.79M12.36M9.6M13.85M34.48M9.99M
Revenue Growth %-1.14%-0.22%0.44%1.49%-0.71%
Cost of Goods Sold+23.64M34.42M984K3.64M3.52M3.93M
COGS % of Revenue4.08%2.78%0.1%0.26%0.1%0.39%
Gross Profit+5.79M-22.06M8.61M10.21M30.95M6.07M
Gross Margin %1%-1.78%0.9%0.74%0.9%0.61%
Gross Profit Growth %--4.81%1.39%0.19%2.03%-0.8%
Operating Expenses+40.09M14.06M75.59M116.61M147.01M172.68M
OpEx % of Revenue6.93%1.14%7.88%8.42%4.26%17.28%
Selling, General & Admin16.46M14.06M23.34M38.02M38.46M46.46M
SG&A % of Revenue2.84%1.14%2.43%2.74%1.12%4.65%
Research & Development23.64M34.42M52.26M82.23M112.08M130.15M
R&D % of Revenue4.08%2.78%5.44%5.94%3.25%13.02%
Other Operating Expenses0-34.42M0-3.64M-3.52M-3.93M
Operating Income+-34.3M-36.12M-66.98M-106.4M-116.06M-166.62M
Operating Margin %-5.93%-2.92%-6.98%-7.68%-3.37%-16.67%
Operating Income Growth %--0.05%-0.85%-0.59%-0.09%-0.44%
EBITDA+-33.55M-35.22M-66M-104.78M-112.53M-162.69M
EBITDA Margin %-5.8%-2.85%-6.88%-7.56%-3.26%-16.28%
EBITDA Growth %--0.05%-0.87%-0.59%-0.07%-0.45%
D&A (Non-Cash Add-back)751K900K984K1.62M3.52M3.93M
EBIT-30.96M-36.11M-66.59M-106.4M-116.06M-166.62M
Net Interest Income+1.04M216K140K4.6M10.7M0
Interest Income1.05M236K148K4.6M10.7M0
Interest Expense4K20K8K000
Other Income/Expense3.34M-3K377K7.05M14.18M17.5M
Pretax Income+-30.97M-36.13M-66.6M-99.35M-101.88M-149.11M
Pretax Margin %-5.35%-2.92%-6.94%-7.17%-2.95%-14.92%
Income Tax+-7.54M-1.82M321K70K193K-9K
Effective Tax Rate %0.76%0.95%1%1%1%1%
Net Income+-23.43M-34.31M-66.92M-99.42M-102.07M-149.1M
Net Margin %-4.05%-2.78%-6.97%-7.18%-2.96%-14.92%
Net Income Growth %--0.46%-0.95%-0.49%-0.03%-0.46%
Net Income (Continuing)-23.43M-34.31M-66.92M-99.42M-102.07M-149.1M
Discontinued Operations000000
Minority Interest000000
EPS (Diluted)+-0.85-1.24-1.11-1.64-1.38-1.65
EPS Growth %--0.46%0.1%-0.48%0.16%-0.2%
EPS (Basic)-0.85-1.24-1.11-1.64-1.38-1.65
Diluted Shares Outstanding27.66M27.66M60.26M60.8M73.81M90.32M
Basic Shares Outstanding27.66M27.66M60.26M60.8M73.81M90.32M
Dividend Payout Ratio------

Balance Sheet

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+57.01M24.31M391.19M260.25M338.84M219.38M
Cash & Short-Term Investments49.47M15.95M375.83M247.66M328.83M209.54M
Cash Only41.07M15.95M240.42M58.34M51.16M16.29M
Short-Term Investments8.4M0135.41M189.32M277.67M193.24M
Accounts Receivable3.98M5.16M8.12M4.66M3.86M3.25M
Days Sales Outstanding251.11152.37308.95122.9140.85118.73
Inventory000000
Days Inventory Outstanding------
Other Current Assets373K423K671K1.12M1.22M1.78M
Total Non-Current Assets+4.92M11.74M51.16M113.52M93.37M93.94M
Property, Plant & Equipment4.33M3.5M4.89M34.91M40.45M39.29M
Fixed Asset Turnover1.34x3.53x1.96x0.40x0.85x0.25x
Goodwill000000
Intangible Assets000000
Long-Term Investments07.63M45.3M77.07M51.33M49.13M
Other Non-Current Assets593K612K975K1.54M1.59M5.52M
Total Assets+61.93M36.05M442.36M373.76M432.21M313.31M
Asset Turnover0.09x0.34x0.02x0.04x0.08x0.03x
Asset Growth %--0.42%11.27%-0.16%0.16%-0.28%
Total Current Liabilities+10.08M12.39M25.83M28.13M28.3M30.65M
Accounts Payable2.54M2.6M3.99M1.15M3.12M2.48M
Days Payables Outstanding39.1827.581.48K114.88323.06230.13
Short-Term Debt532K654K259K000
Deferred Revenue (Current)717K161K1000K1000K1000K1000K
Other Current Liabilities496K629K4.75M7.12M10.62M10.22M
Current Ratio5.66x1.96x15.15x9.25x11.97x7.16x
Quick Ratio5.66x1.96x15.15x9.25x11.97x7.16x
Cash Conversion Cycle------
Total Non-Current Liabilities+44.39M47.09M28.7M44.77M35.51M29.71M
Long-Term Debt0924K0000
Capital Lease Obligations00026.78M25.91M25.06M
Deferred Tax Liabilities650K155K476K381K557K548K
Other Non-Current Liabilities42.76M45.08M6.19M1.65M2.94M785K
Total Liabilities54.47M59.48M54.53M72.89M63.81M60.36M
Total Debt+532K1.58M259K27.75M27.11M26.49M
Net Debt-40.54M-14.38M-240.42M-30.59M-24.05M10.19M
Debt / Equity0.07x-0.00x0.09x0.07x0.10x
Debt / EBITDA------
Net Debt / EBITDA------
Interest Coverage-8576.25x-1806.20x-8372.38x---
Total Equity+7.46M-23.44M387.82M300.87M368.4M252.95M
Equity Growth %--4.14%17.55%-0.22%0.22%-0.31%
Book Value per Share0.27-0.856.444.954.992.80
Total Shareholders' Equity7.46M-23.44M387.82M300.87M368.4M252.95M
Common Stock1K1K6K6K8K9K
Retained Earnings3.44M-30.87M-97.79M-197.22M-299.29M-448.39M
Treasury Stock000000
Accumulated OCI00-135K-1.52M30K255K
Minority Interest000000

Cash Flow

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-32.01M-33.22M-32.52M-90.97M-93.29M-138.2M
Operating CF Margin %-5.53%-2.69%-3.39%-6.57%-2.71%-13.83%
Operating CF Growth %--0.04%0.02%-1.8%-0.03%-0.48%
Net Income-23.43M-34.31M-66.92M-99.42M-102.07M-149.1M
Depreciation & Amortization751K900K984K3.64M3.52M3.93M
Stock-Based Compensation1.23M1M3.45M013.75M16.71M
Deferred Taxes000-95K00
Other Non-Cash Items-2.29M-986K904K9.02M-1.18M-4.61M
Working Capital Changes-8.27M177K29.07M-4.11M-7.32M-5.11M
Change in Receivables-1.09M-1.18M-2.96M3.46M805K608K
Change in Inventory000000
Change in Payables1.18M43K1.14M-2.72M1.82M-354K
Cash from Investing+27.23M6.36M-176.4M-93.25M-68.18M86.61M
Capital Expenditures-884K-317K-2.12M-6.45M-11.61M-4.88M
CapEx % of Revenue0.15%0.03%0.22%0.47%0.34%0.49%
Acquisitions------
Investments------
Other Investing0-988K-1M-600K0-1.61M
Cash from Financing+172K1.74M433.43M2.13M154.3M16.72M
Debt Issued (Net)------
Equity Issued (Net)------
Dividends Paid000000
Share Repurchases------
Other Financing002.55M01.58M1.53M
Net Change in Cash------
Free Cash Flow+-32.89M-34.53M-35.64M-97.42M-104.9M-144.71M
FCF Margin %-5.68%-2.79%-3.71%-7.03%-3.04%-14.48%
FCF Growth %--0.05%-0.03%-1.73%-0.08%-0.38%
FCF per Share-1.19-1.25-0.59-1.60-1.42-1.60
FCF Conversion (FCF/Net Income)1.37x0.97x0.49x0.91x0.91x0.93x
Interest Paid000000
Taxes Paid1.81M21K11K0170K0

Key Ratios

Metric201920202021202220232024
Return on Equity (ROE)-313.96%--36.73%-28.87%-30.5%-47.99%
Return on Invested Capital (ROIC)---91.46%-38.19%-28.32%-41.14%
Gross Margin100%-178.5%89.75%73.71%89.78%60.71%
Net Margin-404.82%-277.55%-697.26%-717.79%-296.05%-1491.95%
Debt / Equity0.07x-0.00x0.09x0.07x0.10x
Interest Coverage-8576.25x-1806.20x-8372.38x---
FCF Conversion1.37x0.97x0.49x0.91x0.91x0.93x
Revenue Growth-113.56%-22.35%44.31%148.91%-71.01%

Revenue by Segment

2021202220232024
Reportable---9.99M
Reportable Growth----

Revenue by Geography

2021202220232024
UNITED STATES8.91M13.3M32.77M9.27M
UNITED STATES Growth-49.25%146.34%-71.71%
Non-US685K548K1.71M724K
Non-US Growth--20.00%211.50%-57.59%

Frequently Asked Questions

Growth & Financials

Caribou Biosciences, Inc. (CRBU) reported $9.3M in revenue for fiscal year 2024. This represents a 61% increase from $5.8M in 2019.

Caribou Biosciences, Inc. (CRBU) saw revenue decline by 71.0% over the past year.

Caribou Biosciences, Inc. (CRBU) reported a net loss of $157.1M for fiscal year 2024.

Dividend & Returns

Caribou Biosciences, Inc. (CRBU) has a return on equity (ROE) of -48.0%. Negative ROE indicates the company is unprofitable.

Caribou Biosciences, Inc. (CRBU) had negative free cash flow of $127.7M in fiscal year 2024, likely due to heavy capital investments.

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