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Enanta Pharmaceuticals, Inc. (ENTA) 10-Year Financial Performance & Capital Metrics

ENTA • • Industrial / General
HealthcareBiotechnologyInfectious DiseasesHepatitis & Viral Infections
AboutEnanta Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs for the treatment of viral infections and liver diseases. Its research and development disease targets include respiratory syncytial virus, SARS-CoV-2, human metapneumovirus, and hepatitis B virus. The company has a collaborative development and license agreement with Abbott Laboratories to identify, develop, and commercialize HCV NS3 and NS3/4A protease inhibitor compounds, including paritaprevir and glecaprevir for the treatment of chronic hepatitis C virus. Enanta Pharmaceuticals, Inc. was founded in 1995 and is headquartered in Watertown, Massachusetts.Show more
  • Revenue $65M -3.4%
  • EBITDA -$80M +32.8%
  • Net Income -$82M +29.4%
  • EPS (Diluted) -3.84 +29.9%
  • Gross Margin 100%
  • EBITDA Margin -122.86% +30.4%
  • Operating Margin -130.65% +27.4%
  • Net Margin -125.36% +26.9%
  • ROE -84.63% -26.0%
  • ROIC -23.23% +14.6%
  • Debt/Equity 3.11 +77.0%
  • Interest Coverage -11.11 +0.1%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 89 (top 11%)

✗Weaknesses

  • ✗High debt to equity ratio of 3.1x
  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Sales declining 11.8% over 5 years
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-8.62%
5Y-11.81%
3Y-8.82%
TTM-9.94%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM20.22%

EPS CAGR

10Y-
5Y-
3Y-
TTM20.73%

ROCE

10Y Avg-11.41%
5Y Avg-31.87%
3Y Avg-33.8%
Latest-30.96%

Peer Comparison

Hepatitis & Viral Infections
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Size & Scale
Valuation
Per Share
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Quality & Returns
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TTM Growth
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COCPCocrystal Pharma, Inc.15.3M1.11-0.65-126.11%0.19
KLRSKalaris Therapeutics Inc165.7M8.86-0.76-170.84%

Profit & Loss

Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Sales/Revenue+88.27M102.81M206.63M205.2M122.47M97.07M86.16M79.2M67.64M65.32M
Revenue Growth %-0.45%0.16%1.01%-0.01%-0.4%-0.21%-0.11%-0.08%-0.15%-0.03%
Cost of Goods Sold+0000000000
COGS % of Revenue----------
Gross Profit+88.27M102.81M206.63M205.2M122.47M97.07M86.16M79.2M67.64M65.32M
Gross Margin %1%1%1%1%1%1%1%1%1%1%
Gross Profit Growth %-0.45%0.16%1.01%-0.01%-0.4%-0.21%-0.11%-0.08%-0.15%-0.03%
Operating Expenses+57.43M78.2M118.3M168.46M164.11M206.65M210M216.41M189.33M150.67M
OpEx % of Revenue0.65%0.76%0.57%0.82%1.34%2.13%2.44%2.73%2.8%2.31%
Selling, General & Admin16.97M20.75M23.44M26.25M27.36M32.54M45.48M52.89M57.85M43.93M
SG&A % of Revenue0.19%0.2%0.11%0.13%0.22%0.34%0.53%0.67%0.86%0.67%
Research & Development40.46M57.45M94.86M142.21M136.76M174.11M164.52M163.52M131.48M106.74M
R&D % of Revenue0.46%0.56%0.46%0.69%1.12%1.79%1.91%2.06%1.94%1.63%
Other Operating Expenses0000000000
Operating Income+30.84M24.61M88.33M36.74M-41.64M-109.57M-123.84M-137.21M-121.69M-85.35M
Operating Margin %0.35%0.24%0.43%0.18%-0.34%-1.13%-1.44%-1.73%-1.8%-1.31%
Operating Income Growth %-0.75%-0.2%2.59%-0.58%-2.13%-1.63%-0.13%-0.11%0.11%0.3%
EBITDA+32.5M26.75M90.85M40M-37.99M-106.24M-120.87M-134.84M-119.36M-80.26M
EBITDA Margin %0.37%0.26%0.44%0.19%-0.31%-1.09%-1.4%-1.7%-1.76%-1.23%
EBITDA Growth %-0.74%-0.18%2.4%-0.56%-1.95%-1.8%-0.14%-0.12%0.11%0.33%
D&A (Non-Cash Add-back)1.66M2.14M2.52M3.26M3.64M3.33M2.97M2.37M2.34M5.09M
EBIT30.84M24.61M88.33M36.74M-41.64M-107.58M-122.19M-125.85M-106.85M-75.87M
Net Interest Income+1.69M2.49M4.85M8.82M6.47M2.02M1.57M6.21M3.83M1.8M
Interest Income1.74M2.53M08.82M6.47M2.02M1.57M11.36M14.77M9.48M
Interest Expense45K40K4.85M00005.15M10.94M7.68M
Other Income/Expense1.72M2.33M4.79M8.82M6.62M1.99M1.66M6.21M3.9M1.8M
Pretax Income+32.56M26.95M93.12M45.56M-35.02M-107.58M-122.19M-131M-117.79M-83.55M
Pretax Margin %0.37%0.26%0.45%0.22%-0.29%-1.11%-1.42%-1.65%-1.74%-1.28%
Income Tax+10.89M9.24M21.16M-826K1.15M-28.58M-433K2.82M-1.74M-1.66M
Effective Tax Rate %0.67%0.66%0.77%1.02%1.03%0.73%1%1.02%0.99%0.98%
Net Income+21.67M17.71M71.96M46.38M-36.17M-79M-121.75M-133.82M-116.05M-81.89M
Net Margin %0.25%0.17%0.35%0.23%-0.3%-0.81%-1.41%-1.69%-1.72%-1.25%
Net Income Growth %-0.73%-0.18%3.06%-0.36%-1.78%-1.18%-0.54%-0.1%0.13%0.29%
Net Income (Continuing)21.67M17.71M71.96M46.38M-36.17M-79M-121.75M-133.82M-116.05M-81.89M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+1.130.913.482.21-1.81-3.92-5.91-6.38-5.48-3.84
EPS Growth %-0.72%-0.19%2.82%-0.36%-1.82%-1.17%-0.51%-0.08%0.14%0.3%
EPS (Basic)1.140.933.482.37-1.81-3.92-5.91-6.38-5.48-3.84
Diluted Shares Outstanding19.22M19.41M20.65M20.97M19.94M20.17M20.6M20.97M21.16M21.34M
Basic Shares Outstanding18.93M19.07M20.65M19.58M19.94M20.17M20.6M20.97M21.16M21.34M
Dividend Payout Ratio----------

Balance Sheet

Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Total Current Assets+232.16M237.82M380.39M401.85M436.84M319.02M311.71M422.79M299.85M204.34M
Cash & Short-Term Investments210.08M223.67M308.73M335.24M386.65M244M249.23M369.91M248.19M188.86M
Cash Only16.58M65.67M63.9M51.23M87.13M57.21M43.99M85.39M37.23M32.3M
Short-Term Investments193.51M157.99M244.83M284.01M299.52M186.8M205.24M284.52M210.95M156.57M
Accounts Receivable12.84M10.61M67.2M51.31M23.49M60.83M49.04M39.62M38.65M6.88M
Days Sales Outstanding53.137.68118.7291.2770.01228.73207.73182.57208.5538.45
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets9.23M3.54M4.45M026.7M14.19M13.45M0608K8.59M
Total Non-Current Assets+49.12M88.82M33.84M87.98M53.95M121.84M68.88M39.48M76.8M76.4M
Property, Plant & Equipment8M8.05M8.37M10.93M15.62M10.65M29.75M34.71M73.35M72.94M
Fixed Asset Turnover11.03x12.77x24.67x18.78x7.84x9.11x2.90x2.28x0.92x0.90x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments32.12M70.04M16.39M65.01M33.24M109.02M33.25M3.97M3.36M3.36M
Other Non-Current Assets608K608K700K700K92K92K696K803K94K92K
Total Assets+281.28M326.64M414.23M489.83M490.79M440.86M380.59M462.27M376.65M280.73M
Asset Turnover0.31x0.31x0.50x0.42x0.25x0.22x0.23x0.17x0.18x0.23x
Asset Growth %0.14%0.16%0.27%0.18%0%-0.1%-0.14%0.21%-0.19%-0.25%
Total Current Liabilities+7.89M20.98M16.02M22.61M24.16M36.17M29.83M62.79M57.53M48.55M
Accounts Payable3.38M3.71M4.75M6.69M5.74M9.54M6M4.1M8M1.95M
Days Payables Outstanding----------
Short-Term Debt00004.26M4.2M2.89M35.08M34.46M33.86M
Deferred Revenue (Current)01000K00000000
Other Current Liabilities09.22M009.38M16.34M14.5M0012.75M
Current Ratio29.43x11.33x23.74x17.77x18.08x8.82x10.45x6.73x5.21x4.21x
Quick Ratio29.43x11.33x23.74x17.77x18.08x8.82x10.45x6.73x5.21x4.21x
Cash Conversion Cycle----------
Total Non-Current Liabilities+3.45M3.98M4.52M4.73M11.05M5.26M29.43M182.75M190.3M167.46M
Long-Term Debt00001.48M1.51M1.42M160.85M136.13M112.44M
Capital Lease Obligations458K379K293K200K3.84M1.13M22.37M21.24M53.94M54.76M
Deferred Tax Liabilities745K1.18M1.79M1.75M4.66M2.07M5.18M000
Other Non-Current Liabilities2.99M3.6M4.23M4.53M1.08M558K454K663K231K260K
Total Liabilities11.34M24.96M20.55M27.34M35.21M41.43M59.26M245.54M247.84M216.01M
Total Debt+531K458K293K200K9.58M6.83M26.69M222.44M226.06M201.06M
Net Debt-16.05M-65.22M-63.61M-51.03M-77.55M-50.37M-17.31M137.05M188.82M168.76M
Debt / Equity0.00x0.00x0.00x0.00x0.02x0.02x0.08x1.03x1.75x3.11x
Debt / EBITDA0.02x0.02x0.00x0.01x------
Net Debt / EBITDA-0.49x-2.44x-0.70x-1.28x------
Interest Coverage685.36x615.35x18.20x-----26.65x-11.12x-11.11x
Total Equity+269.94M301.68M393.68M462.49M455.58M399.43M321.33M216.74M128.81M64.72M
Equity Growth %0.14%0.12%0.3%0.17%-0.01%-0.12%-0.2%-0.33%-0.41%-0.5%
Book Value per Share14.0415.5419.0622.0622.8519.8015.6010.346.093.03
Total Shareholders' Equity269.94M301.68M393.68M462.49M455.58M399.43M321.33M216.74M128.81M64.72M
Common Stock190K191K194K197K201K202K208K211K212K214K
Retained Earnings27.65M45.36M117.36M163.74M127.57M48.58M-73.18M-207M-323.04M-404.93M
Treasury Stock0000000000
Accumulated OCI19K-112K-398K146K844K-382K-3.72M-1.17M302K-339K
Minority Interest0000000000

Cash Flow

Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Cash from Operations+35.81M52.65M29.22M71.42M7.09M-70M-84.78M-103.15M-78.76M-19.27M
Operating CF Margin %0.41%0.51%0.14%0.35%0.06%-0.72%-0.98%-1.3%-1.16%-0.3%
Operating CF Growth %-0.53%0.47%-0.45%1.44%-0.9%-10.88%-0.21%-0.22%0.24%0.76%
Net Income21.67M17.71M71.96M46.38M-36.17M-79M-121.75M-133.82M-116.05M-81.89M
Depreciation & Amortization1.66M2.14M2.52M3.26M3.64M3.33M2.97M2.37M2.34M5.09M
Stock-Based Compensation9.35M13.07M15.85M19.23M19.57M20.99M26.97M28.22M26.8M18.57M
Deferred Taxes-2.29M-1.65M1.86M-3.14M10.61M345K0000
Other Non-Cash Items-749K-581K-1.17M-5.8M-3.47M-1.98M242K-7.95M1.02M40.51M
Working Capital Changes6.17M21.97M-61.79M11.49M12.9M-13.69M6.79M8.02M7.13M-1.55M
Change in Receivables2.45M2.23M-56.59M15.89M27.82M-24.3M11.79M9.42M973K-236K
Change in Inventory1.88M18.63M-6.42M-6.48M000000
Change in Payables1.45M633K1.32M1.79M-883K3.77M-4.63M-1.15M-414K-1.31M
Cash from Investing+-43.66M-4.57M-35.4M-86.66M19.83M36.99M54.9M-53.58M58.23M40.35M
Capital Expenditures-4.74M-2.51M-2.98M-5.42M-1.45M-750K-2.13M-9.06M-17.95M-12.9M
CapEx % of Revenue0.05%0.02%0.01%0.03%0.01%0.01%0.02%0.11%0.27%0.2%
Acquisitions----------
Investments----------
Other Investing-38.92M-2.07M-32.42M0037.74M54.9M-44.52M00
Cash from Financing+2.71M1.02M4.41M2.57M8.98M3.08M20.03M198.13M-27.63M-26.62M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing2.77M1.09M4.49M2.66M8.98M3.08M20.03M198.13M-147K-26.62M
Net Change in Cash----------
Free Cash Flow+31.07M50.15M26.24M66M5.64M-70.75M-86.91M-112.21M-96.71M-32.17M
FCF Margin %0.35%0.49%0.13%0.32%0.05%-0.73%-1.01%-1.42%-1.43%-0.49%
FCF Growth %-0.58%0.61%-0.48%1.52%-0.91%-13.54%-0.23%-0.29%0.14%0.67%
FCF per Share1.622.581.273.150.28-3.51-4.22-5.35-4.57-1.51
FCF Conversion (FCF/Net Income)1.65x2.97x0.41x1.54x-0.20x0.89x0.70x0.77x0.68x0.24x
Interest Paid00000001.99M11.71M0
Taxes Paid12.62M1.59M26.09M12.67M105K32K04.9M241K0

Key Ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)8.56%6.2%20.7%10.84%-7.88%-18.48%-33.78%-49.74%-67.17%-84.63%
Return on Invested Capital (ROIC)9.87%7.53%23.39%7.43%-7.91%-22.61%-28.44%-31.29%-27.19%-23.23%
Gross Margin100%100%100%100%100%100%100%100%100%100%
Net Margin24.55%17.23%34.82%22.6%-29.53%-81.38%-141.31%-168.95%-171.58%-125.36%
Debt / Equity0.00x0.00x0.00x0.00x0.02x0.02x0.08x1.03x1.75x3.11x
Interest Coverage685.36x615.35x18.20x-----26.65x-11.12x-11.11x
FCF Conversion1.65x2.97x0.41x1.54x-0.20x0.89x0.70x0.77x0.68x0.24x
Revenue Growth-45.13%16.48%100.97%-0.69%-40.31%-20.74%-11.24%-8.07%-14.61%-3.42%

Revenue by Segment

2018201920202021202320242025
Royalty191.63M205.2M122.47M97.07M78.2M67.64M65.32M
Royalty Growth-7.08%-40.31%-20.74%-19.44%-13.51%-3.42%
License----1M--
License Growth-------
Milestone15M------
Milestone Growth-------

Frequently Asked Questions

Growth & Financials

Enanta Pharmaceuticals, Inc. (ENTA) reported $64.8M in revenue for fiscal year 2025. This represents a 55% increase from $41.7M in 2012.

Enanta Pharmaceuticals, Inc. (ENTA) saw revenue decline by 3.4% over the past year.

Enanta Pharmaceuticals, Inc. (ENTA) reported a net loss of $92.0M for fiscal year 2025.

Dividend & Returns

Enanta Pharmaceuticals, Inc. (ENTA) has a return on equity (ROE) of -84.6%. Negative ROE indicates the company is unprofitable.

Enanta Pharmaceuticals, Inc. (ENTA) had negative free cash flow of $43.6M in fiscal year 2025, likely due to heavy capital investments.

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