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INO logoInovio Pharmaceuticals, Inc.(INO)Earnings, Financials & Key Ratios

INO•NASDAQ
$1.24
$581M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutInovio Pharmaceuticals, Inc., a biotechnology company, focuses on the discovery, development, and commercialization of DNA medicines to treat and protect people from diseases associated with human papillomavirus (HPV), cancer, and infectious diseases. Its DNA medicines platform uses precisely designed SynCon that identify and optimize the DNA sequence of the target antigen, as well as CELLECTRA smart devices technology that facilitates delivery of the DNA plasmids. The company engages in conducting and planning clinical studies of its DNA medicines for HPV-associated precancers, including cervical, vulvar, and anal dysplasia; HPV-associated cancers, such as head and neck, cervical, anal, penile, vulvar, and vaginal; other HPV-associated disorders, including recurrent respiratory papillomatosis; glioblastoma multiforme; prostate cancer; HIV; Ebola; Middle East Respiratory Syndrome (MERS); and Lassa fever. Its partners and collaborators include ApolloBio Corp., AstraZeneca, Beijing Advaccine Biotechnology Co., Ltd., The Bill & Melinda Gates Foundation, Coalition for Epidemic Preparedness Innovations (CEPI), Defense Advanced Research Projects Agency (DARPA), Department of Defense (DoD), HIV Vaccines Trial Network, International Vaccine Institute, Kaneka Eurogentec, Medical CBRN Defense Consortium (MCDC), National Cancer Institute, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Ology Bioservices, the Parker Institute for Cancer Immunotherapy, Plumbline Life Sciences, Regeneron Pharmaceuticals, Thermo Fisher Scientific, University of Pennsylvania, Walter Reed Army Institute of Research, and The Wistar Institute. The company has an agreement with Richter-Helm BioLogics GmbH & Co. KG to support investigational DNA vaccine INO-4800 for COVID-19; and a partnership with International Vaccine Institute and Seoul National University Hospital. The company was founded in 1979 and is headquartered in Plymouth Meeting, Pennsylvania.Show more
  • Revenue$0-100.0%
  • EBITDA-$86.82B-79357.3%
  • Net Income-$84.95B-79100.6%
  • EPS (Diluted)-1.81+54.2%
  • ROE-703.06%-509.1%
  • Debt/Equity0.39+124.5%
Technical→

INO Key Insights

Inovio Pharmaceuticals, Inc. (INO) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Trading at only 0.0x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 0/9
  • ✗Weak momentum: RS Rating 6 (bottom 6%)
  • ✗Shares diluted 100.0% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

INO Price & Volume

Inovio Pharmaceuticals, Inc. (INO) stock price & volume — 10-year historical chart

Loading chart...

INO Growth Metrics

Inovio Pharmaceuticals, Inc. (INO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-100%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-79100.59%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM99.8%

Return on Capital

10 Years-122.52%
5 Years-178.68%
3 Years-250%
Last Year-565.26%

INO Recent Earnings

Inovio Pharmaceuticals, Inc. (INO) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)●Beat Revenue 3/12 qtrs (43%)
Q2 2026Latest
Mar 12, 2026
EPS
$0.31
Est $0.37
+183.8%
Revenue
—
Est $333,330
Q4 2025
Nov 10, 2025
EPS
$0.44
Est $0.51
+13.7%
Revenue
—
Q3 2025
Aug 12, 2025
EPS
$0.61
Est $0.63
+3.2%
Revenue
—
Est $10,000
Q2 2025
May 13, 2025
EPS
$0.51
Est $0.74
+31.1%
Revenue
$65,343
Est $10,000
+553.4%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 12, 2026
$0.31vs $0.37+183.8%
—vs $333,330
Q4 2025Nov 10, 2025
$0.44vs $0.51+13.7%
—
Q3 2025Aug 12, 2025
$0.61vs $0.63+3.2%
—vs $10,000
Q2 2025May 13, 2025
$0.51vs $0.74+31.1%
$65,343vs $10,000+553.4%
Based on last 12 quarters of dataView full earnings history →

INO Peer Comparison

Inovio Pharmaceuticals, Inc. (INO) competitors in Vaccines and Infectious Disease — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
NVAX logoNVAXNovavax, Inc.Direct Competitor1.53B9.363.6964.69%-14.73%
OCGN logoOCGNOcugen, Inc.Direct Competitor492.54M1.46-6.338.83%-15.37%-26.26%
DVAX logoDVAXDynavax Technologies CorporationDirect Competitor1.82B15.5077.5019.36%-13.13%-8.13%0.43
VXRT logoVXRTVaxart, Inc.Direct Competitor179.17M0.7510.647.27%6.88%33.83%0.10
AGEN logoAGENAgenus Inc.Direct Competitor137.4M3.89-1144.1210.37%0.1%
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.67B85.09-8.75-43.89%-192.87%-356.81%0.95
MRNA logoMRNAModerna, Inc.Product Competitor19.35B48.79-6.72-39.23%-143.55%-36.73%0.22
BNTX logoBNTXBioNTech SEProduct Competitor23.94B95.26-18.000.2%-39.6%-6.03%0.01

Compare INO vs Peers

Inovio Pharmaceuticals, Inc. (INO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NVAX

Most directly comparable listed peer for INO.

Scale Benchmark

vs TMO

Larger-name benchmark to compare INO against a more recognizable public peer.

Peer Set

Compare Top 5

vs NVAX, OCGN, DVAX, VXRT

INO Income Statement

Inovio Pharmaceuticals, Inc. (INO) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue42.22M30.48M4.11M7.41M1.77M10.26M832.01K217.76K0
Revenue Growth %19.37%-27.8%-86.51%80.24%-76.05%478.23%-91.89%-73.83%-100%
Cost of Goods Sold000000000
COGS % of Revenue---------
Gross Profit
42.22M▲ 0%
30.48M▼ 27.8%
4.11M▼ 86.5%
7.41M▲ 80.2%
1.77M▼ 76.1%
10.26M▲ 478.2%
832.01K▼ 91.9%
217.76K▼ 73.8%
0▼ 100.0%
Gross Margin %100%100%100%100%100%100%100%100%-
Gross Profit Growth %19.37%-27.8%-86.51%80.24%-76.05%478.23%-91.89%-73.83%-100%
Operating Expenses126.86M124.57M115.22M131.49M302.99M277.84M144.77M112.62M86.89B
OpEx % of Revenue300.48%408.68%2802.1%1774.25%17072.34%2707.35%17400.28%51716.91%-
Selling, General & Admin28.29M29.32M27.2M37.25M53.75M90.19M47.58M37M32.68B
SG&A % of Revenue67.01%96.17%661.57%502.59%3028.71%878.8%5718.93%16989.81%-
Research & Development98.57M95.26M88.02M94.25M249.24M187.65M86.68M75.62M54.21B
R&D % of Revenue233.47%312.51%2140.54%1271.66%14043.62%1828.55%10417.73%34727.1%-
Other Operating Expenses806.82K360.8K000010.51M00
Operating Income
-83.64M▲ 0%
-94.09M▼ 12.5%
-111.11M▼ 18.1%
-124.08M▼ 11.7%
-301.22M▼ 142.8%
-267.57M▲ 11.2%
-143.94M▲ 46.2%
-112.4M▲ 21.9%
-86.82B▼ 77144.6%
Operating Margin %-198.11%-308.68%-2702.1%-1674.25%-16972.34%-2607.35%-17300.28%-51616.91%-
Operating Income Growth %-9.72%-12.49%-18.09%-11.68%-142.76%11.17%46.21%21.91%-77144.61%
EBITDA-80.17M-89.09M-105.59M-119.45M-296.49M-262.08M-140.44M-109.27M-86.82B
EBITDA Margin %-189.9%-292.29%-2567.95%-1611.8%-16705.78%-2553.8%-16879.18%-50179.5%-
EBITDA Growth %-9.6%-11.13%-18.52%-13.13%-148.2%11.61%46.41%22.19%-79357.3%
D&A (Non-Cash Add-back)3.47M5M5.52M4.63M4.73M5.5M3.5M3.13M0
EBIT-88.18M-94.8M-112.86M-154.19M-301.29M-276.4M-133.89M-107.08M0
Net Interest Income1.81M2.26M-5.34M-5.39M1.43M3.53M6.91M4.59M0
Interest Income1.84M2.26M2.61M3.31M3.36M4.78M8.13M4.77M2.42B
Interest Expense25.93K07.95M8.7M1.94M1.25M1.22M177.83K0
Other Income/Expense-4.56M-706.88K-9.7M-43.39M-2.44M-12.24M8.82M5.14M1.88B
Pretax Income
-88.21M▲ 0%
-94.8M▼ 7.5%
-120.81M▼ 27.4%
-167.47M▼ 38.6%
-303.66M▼ 81.3%
-279.82M▲ 7.9%
-135.12M▲ 51.7%
-107.25M▲ 20.6%
-84.95B▼ 79100.6%
Pretax Margin %-208.92%-311%-2938.01%-2259.75%-17109.87%-2726.67%-16239.87%-49254.27%-
Income Tax02.17M-257.33K000000
Effective Tax Rate %0%-2.29%0.21%0%0%0%0%0%0%
Net Income
-88.21M▲ 0%
-96.97M▼ 9.9%
-119.36M▼ 23.1%
-166.41M▼ 39.4%
-303.66M▼ 82.5%
-279.82M▲ 7.9%
-135.12M▲ 51.7%
-107.25M▲ 20.6%
-84.95B▼ 79100.6%
Net Margin %-208.92%-318.12%-2902.75%-2245.39%-17109.87%-2726.67%-16239.87%-49254.27%-
Net Income Growth %-19.62%-9.93%-23.09%-39.42%-82.47%7.85%51.71%20.62%-79100.59%
Net Income (Continuing)-88.21M-96.97M-120.55M-167.47M-303.66M-279.82M-135.12M-107.25M-84.95B
Discontinued Operations000000000
Minority Interest96.27K96.27K1.97M000000
EPS (Diluted)
-1.08▲ 0%
-1.05▲ 2.8%
-0.97▲ 7.6%
-1.07▼ 10.3%
-1.42▼ 32.7%
-14.07▼ 890.8%
-6.09▲ 56.7%
-3.95▲ 35.1%
-1.81▲ 54.2%
EPS Growth %-6.93%2.78%7.62%-10.31%-32.71%-890.85%56.72%35.14%54.18%
EPS (Basic)-1.08-1.05-0.97-1.07-1.42-14.07-6.09-3.95-1.81
Diluted Shares Outstanding81.92M92.54M124.62M169.87M214.62M19.89M22.17M27.16M468.86M
Basic Shares Outstanding81.78M92.35M124.62M165.36M214.62M19.89M22.17M27.16M468.86M
Dividend Payout Ratio---------

INO Balance Sheet

Inovio Pharmaceuticals, Inc. (INO) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets138.36M87.81M94.2M471.17M448.44M315.24M153.11M97.83M61.12B
Cash & Short-Term Investments127.43M81.23M89.53M411.64M401.31M253M145.29M94.11M58.51B
Cash Only23.79M23.69M22.2M250.73M71.14M46.33M14.31M65.81M44.27B
Short-Term Investments103.64M57.54M67.34M160.91M330.17M206.67M130.98M28.3M14.24B
Accounts Receivable6.49M4.05M2.03M19.06M8.03M11.74M2.41M1.2M0
Days Sales Outstanding56.1148.56180.38938.881.65K417.51.06K2.01K-
Inventory000000000
Days Inventory Outstanding---------
Other Current Assets0000261.19K30.38M20.43K02.61B
Total Non-Current Assets48.88M43.3M49.75M68.6M47.5M33.29M17.84M15.37M13.19B
Property, Plant & Equipment18.32M15.95M26.56M24.09M29.02M17.96M14.45M11.77M9.07B
Fixed Asset Turnover2.30x1.91x0.15x0.31x0.06x0.57x0.06x0.02x-
Goodwill10.51M10.51M10.51M10.51M10.51M10.51M000
Intangible Assets6.01M4.76M3.69M3.15M2.63M2.13M000
Long-Term Investments11.39M9.41M6.32M4.89M3.91M2.01M2.78M1.61M2.1B
Other Non-Current Assets2.64M2.67M2.67M25.96M1.43M684.04K605.32K1.98M2.01B
Total Assets
187.24M▲ 0%
131.11M▼ 30.0%
143.95M▲ 9.8%
539.77M▲ 275.0%
495.94M▼ 8.1%
348.53M▼ 29.7%
170.95M▼ 51.0%
113.2M▼ 33.8%
74.31B▲ 65546.5%
Asset Turnover0.23x0.23x0.03x0.01x0.00x0.03x0.00x0.00x-
Asset Growth %7.79%-29.98%9.79%274.97%-8.12%-29.72%-50.95%-33.78%65546.53%
Total Current Liabilities35.41M35.3M31.99M41.71M65.74M96.87M42.57M35.33M43.67B
Accounts Payable8.49M11.02M7.65M1.47M27.97M21.08M4.65M6.44M0
Days Payables Outstanding---------
Short-Term Debt00000016.77M02.82B
Deferred Revenue (Current)1.35M257.15K124.13K46.63K21.63K0000
Other Current Liabilities9.24M14.73M15.74M20.66M20.71M15.14M9.95M23.26M40.85B
Current Ratio3.91x2.49x2.94x11.30x6.82x3.25x3.60x2.77x1.40x
Quick Ratio3.91x2.49x2.94x11.30x6.82x3.25x3.60x2.77x1.40x
Cash Conversion Cycle---------
Total Non-Current Liabilities9.35M8.78M106.56M36.93M30.53M29.3M11.03M9.37M6.55B
Long-Term Debt0077.02M18.66M14.96M16.61M006.55B
Capital Lease Obligations0020.41M18.06M15.46M12.66M11.03M9.37M0
Deferred Tax Liabilities24.77K24.77K32.05K32.05K32.05K32.05K000
Other Non-Current Liabilities9.1M8.61M8.99M95.16K14.83K0000
Total Liabilities44.75M44.08M138.55M78.63M96.27M126.17M53.6M44.69M50.21B
Total Debt0099.51M39.05M33.02M32.07M30.21M11.87M9.37B
Net Debt-23.79M-23.69M77.31M-211.68M-38.12M-14.25M15.9M-53.95M-34.91B
Debt / Equity--18.41x0.08x0.08x0.14x0.26x0.17x0.39x
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage-3225.35x--13.98x-14.26x-155.55x-213.38x-117.71x-632.05x-
Total Equity
142.49M▲ 0%
87.03M▼ 38.9%
5.4M▼ 93.8%
461.14M▲ 8432.0%
399.67M▼ 13.3%
222.36M▼ 44.4%
117.35M▼ 47.2%
68.5M▼ 41.6%
24.1B▲ 35075.1%
Equity Growth %15.49%-38.92%-93.79%8431.97%-13.33%-44.36%-47.23%-41.62%35075.1%
Book Value per Share1.740.940.042.711.8611.185.292.5251.39
Total Shareholders' Equity142.39M86.94M3.44M461.14M399.67M222.36M117.35M68.5M24.1B
Common Stock90.36K97.23K101.36K186.85K217.38K21.09K22.79K36.1K29.14B
Retained Earnings-523.36M-620.43M-739.79M-906.2M-1.21B-1.49B-1.62B-1.73B-1.82T
Treasury Stock000000000
Accumulated OCI-117K-528.87K472.61K-256.15K-282.24K-698.74K-662.6K-675.67K-637.96M
Minority Interest96.27K96.27K1.97M000000

INO Cash Flow Statement

Inovio Pharmaceuticals, Inc. (INO) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-63.21M-73.55M-97.85M-177.98M-215.71M-216.22M-124.37M-104.08M-88.63B
Operating CF Margin %-149.71%-241.29%-2379.66%-2401.48%-12154.25%-2106.9%-14947.6%-47795.03%-
Operating CF Growth %-1.05%-16.36%-33.04%-81.89%-21.2%-0.24%42.48%16.31%-85057.92%
Net Income-88.21M-96.97M-120.55M-167.47M-303.66M-279.82M-135.12M-107.25M-84.95B
Depreciation & Amortization3.47M5M5.52M4.63M4.73M5.5M3.5M3.13M2.99B
Stock-Based Compensation13.07M10.65M10.9M15.65M26.34M22.56M11.07M6.6M3.76B
Deferred Taxes-150.03K3.42M-260.82K37.93M04.03M-32.05K00
Other Non-Cash Items5.71M-360.8K10.09M2.36M6.53M11.69M6.47M-3.88M-10.43B
Working Capital Changes2.9M4.71M-3.54M-71.07M50.35M19.83M-10.26M-2.66M0
Change in Receivables10.08M2.43M2.02M-17.02M11.03M-3.71M9.33M1.21M0
Change in Inventory531.87K-963.92K935.79K-55.15M00000
Change in Payables2.68M601.26K-4.59M3.25M26.14M32.61M-45.99M-3.37M-6.42B
Cash from Investing-27.83M42.42M-9.04M-58.8M-175.34M109.59M87.36M104.07M14.04B
Capital Expenditures-10.29M-2.09M-987.93K-1.52M-1.23M-969.15K-320.9K-487.83K0
CapEx % of Revenue24.38%6.84%24.03%20.52%69.36%9.44%38.57%224.03%-
Acquisitions02.78T987.93B38.73M0-2M6.22M00
Investments---------
Other Investing1M-2.78T-987.93B-2.77M00059.32K-1.18B
Cash from Financing95.69M31.04M105.4M465.28M211.5M81.84M5M51.48M53.05B
Debt Issued (Net)0097.44M171.62K000-16.41M0
Equity Issued (Net)1000K1000K1000K1000K1000K1000K1000K1000K0
Dividends Paid000000000
Share Repurchases000000000
Other Financing1.34M1.81M-1.14M10.62M2.06M-1.11M-466.65K-420.8K53.05B
Net Change in Cash
4.65M▲ 0%
-92.95K▼ 102.0%
-1.5M▼ 1511.2%
228.53M▲ 15360.5%
-179.58M▼ 178.6%
-24.81M▲ 86.2%
-32.02M▼ 29.0%
51.5M▲ 260.9%
-21.54B▼ 41923.2%
Free Cash Flow
-73.5M▲ 0%
-75.64M▼ 2.9%
-98.84M▼ 30.7%
-179.5M▼ 81.6%
-216.94M▼ 20.9%
-217.18M▼ 0.1%
-124.69M▲ 42.6%
-104.56M▲ 16.1%
-88.63B▼ 84660.6%
FCF Margin %-174.09%-248.13%-2403.69%-2422%-12223.61%-2116.34%-14986.17%-48019.06%-
FCF Growth %-10.54%-2.9%-30.68%-81.61%-20.86%-0.11%42.59%16.14%-84660.63%
FCF per Share-0.90-0.82-0.79-1.06-1.01-10.92-5.62-3.85-189.03
FCF Conversion (FCF/Net Income)0.72x0.76x0.82x1.07x0.71x0.77x0.92x0.97x1.04x
Interest Paid0004.62M1.08M1.07M000
Taxes Paid002.72M4.62M1.08M1.07M000

INO Key Ratios

Inovio Pharmaceuticals, Inc. (INO) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-49.27%-66.35%-84.5%-258.25%-71.34%-70.55%-89.97%-79.55%-115.42%-703.06%
Return on Invested Capital (ROIC)-51.39%-56.28%-77.53%-114.11%-56.03%-73.95%-70.46%-63.25%-114.07%-
Gross Margin100%100%100%100%100%100%100%100%100%-
Net Margin-208.49%-208.92%-318.12%-2902.75%-2245.39%-17109.87%-2726.67%-16239.87%-49254.27%-
Debt / Equity---18.41x0.08x0.08x0.14x0.26x0.17x0.39x
Interest Coverage-547.48x-3225.35x--13.98x-14.26x-155.55x-213.38x-117.71x-632.05x-
FCF Conversion0.85x0.72x0.76x0.82x1.07x0.71x0.77x0.92x0.97x1.04x
Revenue Growth-12.83%19.37%-27.8%-86.51%80.24%-76.05%478.23%-91.89%-73.83%-100%

INO SEC Filings & Documents

Inovio Pharmaceuticals, Inc. (INO) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 6, 2026·SEC

Material company update

Apr 2, 2026·SEC

Material company update

Mar 12, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 12, 2026·SEC

FY 2025

Mar 18, 2025·SEC

FY 2024

Mar 6, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 12, 2025·SEC

FY 2025

May 13, 2025·SEC

INO Frequently Asked Questions

Inovio Pharmaceuticals, Inc. (INO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Inovio Pharmaceuticals, Inc. (INO) saw revenue decline by 100.0% over the past year.

Inovio Pharmaceuticals, Inc. (INO) reported a net loss of $84.95B for fiscal year 2025.

Dividend & Returns

Inovio Pharmaceuticals, Inc. (INO) has a return on equity (ROE) of -703.1%. Negative ROE indicates the company is unprofitable.

Inovio Pharmaceuticals, Inc. (INO) had negative free cash flow of $19.44B in fiscal year 2025, likely due to heavy capital investments.

Explore More INO

Inovio Pharmaceuticals, Inc. (INO) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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