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Inovio Pharmaceuticals, Inc. (INO) 10-Year Financial Performance & Capital Metrics

INO • • Industrial / General
HealthcareBiotechnologyInfectious DiseasesHepatitis & Viral Infections
AboutInovio Pharmaceuticals, Inc., a biotechnology company, focuses on the discovery, development, and commercialization of DNA medicines to treat and protect people from diseases associated with human papillomavirus (HPV), cancer, and infectious diseases. Its DNA medicines platform uses precisely designed SynCon that identify and optimize the DNA sequence of the target antigen, as well as CELLECTRA smart devices technology that facilitates delivery of the DNA plasmids. The company engages in conducting and planning clinical studies of its DNA medicines for HPV-associated precancers, including cervical, vulvar, and anal dysplasia; HPV-associated cancers, such as head and neck, cervical, anal, penile, vulvar, and vaginal; other HPV-associated disorders, including recurrent respiratory papillomatosis; glioblastoma multiforme; prostate cancer; HIV; Ebola; Middle East Respiratory Syndrome (MERS); and Lassa fever. Its partners and collaborators include ApolloBio Corp., AstraZeneca, Beijing Advaccine Biotechnology Co., Ltd., The Bill & Melinda Gates Foundation, Coalition for Epidemic Preparedness Innovations (CEPI), Defense Advanced Research Projects Agency (DARPA), Department of Defense (DoD), HIV Vaccines Trial Network, International Vaccine Institute, Kaneka Eurogentec, Medical CBRN Defense Consortium (MCDC), National Cancer Institute, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Ology Bioservices, the Parker Institute for Cancer Immunotherapy, Plumbline Life Sciences, Regeneron Pharmaceuticals, Thermo Fisher Scientific, University of Pennsylvania, Walter Reed Army Institute of Research, and The Wistar Institute. The company has an agreement with Richter-Helm BioLogics GmbH & Co. KG to support investigational DNA vaccine INO-4800 for COVID-19; and a partnership with International Vaccine Institute and Seoul National University Hospital. The company was founded in 1979 and is headquartered in Plymouth Meeting, Pennsylvania.Show more
  • Revenue $218K -73.8%
  • EBITDA -$109M +22.2%
  • Net Income -$107M +20.6%
  • EPS (Diluted) -3.95 +35.1%
  • Gross Margin 100%
  • EBITDA Margin -50179.5% -197.3%
  • Operating Margin -51616.91% -198.4%
  • Net Margin -49254.27% -203.3%
  • ROE -115.42% -45.1%
  • ROIC -114.07% -80.3%
  • Debt/Equity 0.17 -32.7%
  • Interest Coverage -632.05 -436.9%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Trading at only 0.6x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 17 (bottom 17%)
  • ✗Sales declining 44.4% over 5 years
  • ✗Shares diluted 22.5% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-32.1%
5Y-44.44%
3Y-50.31%
TTM-10.36%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM4.24%

EPS CAGR

10Y-
5Y-
3Y-
TTM19%

ROCE

10Y Avg-68.28%
5Y Avg-73.76%
3Y Avg-87.74%
Latest-108.99%

Peer Comparison

Hepatitis & Viral Infections
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Per Share
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Profitability
Quality & Returns
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Sector-Specific
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ADMAADMA Biologics, Inc.4.16B17.5021.6065.15%42.87%48.57%2.64%0.24
CVACCureVac N.V.1.05B4.666.478.96%37.93%33.02%7.95%0.06
DWTXDogwood Therapeutics, Inc.83.24M2.80-0.22-49.37%0.24
ALGSAligos Therapeutics, Inc.44.22M8.26-0.39-74.6%-32.68%-120.37%
INOInovio Pharmaceuticals, Inc.108.55M1.58-0.40-73.83%-592.82%-115.42%0.17
BRNSBarinthus Biotherapeutics plc29.81M0.73-0.4717.66%-408%-89.73%0.09
COCPCocrystal Pharma, Inc.15.3M1.11-0.65-126.11%0.19
KLRSKalaris Therapeutics Inc165.7M8.86-0.76-170.84%

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+40.57M35.37M42.22M30.48M4.11M7.41M1.77M10.26M832.01K217.76K
Revenue Growth %2.88%-0.13%0.19%-0.28%-0.87%0.8%-0.76%4.78%-0.92%-0.74%
Cost of Goods Sold+0000000000
COGS % of Revenue----------
Gross Profit+40.57M35.37M42.22M30.48M4.11M7.41M1.77M10.26M832.01K217.76K
Gross Margin %1%1%1%1%1%1%1%1%1%1%
Gross Profit Growth %2.88%-0.13%0.19%-0.28%-0.87%0.8%-0.76%4.78%-0.92%-0.74%
Operating Expenses+75.86M112.6M126.86M124.57M115.22M131.49M302.99M277.84M144.77M112.62M
OpEx % of Revenue1.87%3.18%3%4.09%28.02%17.74%170.72%27.07%174%517.17%
Selling, General & Admin18.06M23.89M28.29M29.32M27.2M37.25M53.75M90.19M47.58M37M
SG&A % of Revenue0.45%0.68%0.67%0.96%6.62%5.03%30.29%8.79%57.19%169.9%
Research & Development57.79M88.71M98.57M95.26M88.02M94.25M249.24M187.65M86.68M75.62M
R&D % of Revenue1.42%2.51%2.33%3.13%21.41%12.72%140.44%18.29%104.18%347.27%
Other Operating Expenses177.56K127.55K806.82K360.8K000010.51M0
Operating Income+-34.28M-76.24M-83.64M-94.09M-111.11M-124.08M-301.22M-267.57M-143.94M-112.4M
Operating Margin %-0.85%-2.16%-1.98%-3.09%-27.02%-16.74%-169.72%-26.07%-173%-516.17%
Operating Income Growth %0.13%-1.22%-0.1%-0.12%-0.18%-0.12%-1.43%0.11%0.46%0.22%
EBITDA+-32.37M-73.15M-80.17M-89.09M-105.59M-119.45M-296.49M-262.08M-140.44M-109.27M
EBITDA Margin %-0.8%-2.07%-1.9%-2.92%-25.68%-16.12%-167.06%-25.54%-168.79%-501.8%
EBITDA Growth %0.15%-1.26%-0.1%-0.11%-0.19%-0.13%-1.48%0.12%0.46%0.22%
D&A (Non-Cash Add-back)1.92M3.09M3.47M5M5.52M4.63M4.73M5.5M3.5M3.13M
EBIT-35.28M-77.24M-88.18M-94.8M-112.86M-154.19M-301.29M-276.4M-133.89M-107.08M
Net Interest Income+305.07K1.26M1.81M2.26M-5.34M-5.39M1.43M3.53M6.91M4.59M
Interest Income305.07K1.4M1.84M2.26M2.61M3.31M3.36M4.78M8.13M4.77M
Interest Expense0139.25K25.93K07.95M8.7M1.94M1.25M1.22M177.83K
Other Income/Expense3.08M2.5M-4.56M-706.88K-9.7M-43.39M-2.44M-12.24M8.82M5.14M
Pretax Income+-31.2M-73.74M-88.21M-94.8M-120.81M-167.47M-303.66M-279.82M-135.12M-107.25M
Pretax Margin %-0.77%-2.08%-2.09%-3.11%-29.38%-22.6%-171.1%-27.27%-162.4%-492.54%
Income Tax+-2.1M002.17M-257.33K00000
Effective Tax Rate %0.94%1%1%1.02%0.99%0.99%1%1%1%1%
Net Income+-29.19M-73.74M-88.21M-96.97M-119.36M-166.41M-303.66M-279.82M-135.12M-107.25M
Net Margin %-0.72%-2.08%-2.09%-3.18%-29.03%-22.45%-171.1%-27.27%-162.4%-492.54%
Net Income Growth %0.19%-1.53%-0.2%-0.1%-0.23%-0.39%-0.82%0.08%0.52%0.21%
Net Income (Continuing)-29.1M-73.74M-88.21M-96.97M-120.55M-167.47M-303.66M-279.82M-135.12M-107.25M
Discontinued Operations0000000000
Minority Interest245.83K96.27K96.27K96.27K1.97M00000
EPS (Diluted)+-0.43-1.01-1.08-1.05-0.97-1.07-1.42-14.07-6.09-3.95
EPS Growth %0.3%-1.35%-0.07%0.03%0.08%-0.1%-0.33%-8.91%0.57%0.35%
EPS (Basic)-0.43-1.01-1.08-1.05-0.97-1.07-1.42-14.07-6.09-3.95
Diluted Shares Outstanding68.37M73.21M81.92M92.54M124.62M169.87M214.62M19.89M22.17M27.16M
Basic Shares Outstanding68.2M73.01M81.78M92.35M124.62M165.36M214.62M19.89M22.17M27.16M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+171.85M124.6M138.36M87.81M94.2M471.17M448.44M315.24M153.11M97.83M
Cash & Short-Term Investments162.99M104.77M127.43M81.23M89.53M411.64M401.31M253M145.29M94.11M
Cash Only57.63M19.14M23.79M23.69M22.2M250.73M71.14M46.33M14.31M65.81M
Short-Term Investments105.36M85.63M103.64M57.54M67.34M160.91M330.17M206.67M130.98M28.3M
Accounts Receivable7.33M16.57M6.49M4.05M2.03M19.06M8.03M11.74M2.41M1.2M
Days Sales Outstanding65.9717156.1148.56180.38938.881.65K417.51.06K2.01K
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets000000261.19K30.38M20.43K0
Total Non-Current Assets+41.99M49.11M48.88M43.3M49.75M68.6M47.5M33.29M17.84M15.37M
Property, Plant & Equipment7.31M9.03M18.32M15.95M26.56M24.09M29.02M17.96M14.45M11.77M
Fixed Asset Turnover5.55x3.92x2.30x1.91x0.15x0.31x0.06x0.57x0.06x0.02x
Goodwill10.11M10.51M10.51M10.51M10.51M10.51M10.51M10.51M00
Intangible Assets3.91M7.63M6.01M4.76M3.69M3.15M2.63M2.13M00
Long-Term Investments19.99M19.83M11.39M9.41M6.32M4.89M3.91M2.01M2.78M1.61M
Other Non-Current Assets676.8K2.11M2.64M2.67M2.67M25.96M1.43M684.04K605.32K1.98M
Total Assets+213.84M173.71M187.24M131.11M143.95M539.77M495.94M348.53M170.95M113.2M
Asset Turnover0.19x0.20x0.23x0.23x0.03x0.01x0.00x0.03x0.00x0.00x
Asset Growth %0.62%-0.19%0.08%-0.3%0.1%2.75%-0.08%-0.3%-0.51%-0.34%
Total Current Liabilities+31.47M43.82M35.41M35.3M31.99M41.71M65.74M96.87M42.57M35.33M
Accounts Payable4.46M6.99M8.49M11.02M7.65M1.47M27.97M21.08M4.65M6.44M
Days Payables Outstanding----------
Short-Term Debt0000000016.77M0
Deferred Revenue (Current)1000K1000K1000K257.15K124.13K46.63K21.63K000
Other Current Liabilities5.84M8.15M9.24M14.73M15.74M20.66M20.71M15.14M9.95M23.26M
Current Ratio5.46x2.84x3.91x2.49x2.94x11.30x6.82x3.25x3.60x2.77x
Quick Ratio5.46x2.84x3.91x2.49x2.94x11.30x6.82x3.25x3.60x2.77x
Cash Conversion Cycle----------
Total Non-Current Liabilities+6.44M6.51M9.35M8.78M106.56M36.93M30.53M29.3M11.03M9.37M
Long-Term Debt000077.02M18.66M14.96M16.61M00
Capital Lease Obligations000020.41M18.06M15.46M12.66M11.03M9.37M
Deferred Tax Liabilities175.64K174.79K24.77K24.77K32.05K32.05K32.05K32.05K00
Other Non-Current Liabilities5.49M5.93M9.1M8.61M8.99M95.16K14.83K000
Total Liabilities37.91M50.33M44.75M44.08M138.55M78.63M96.27M126.17M53.6M44.69M
Total Debt+000099.51M39.05M33.02M32.07M30.21M11.87M
Net Debt-57.63M-19.14M-23.79M-23.69M77.31M-211.68M-38.12M-14.25M15.9M-53.95M
Debt / Equity----18.41x0.08x0.08x0.14x0.26x0.17x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage--547.48x-3225.35x--13.98x-14.26x-155.55x-213.38x-117.71x-632.05x
Total Equity+175.93M123.38M142.49M87.03M5.4M461.14M399.67M222.36M117.35M68.5M
Equity Growth %0.58%-0.3%0.15%-0.39%-0.94%84.32%-0.13%-0.44%-0.47%-0.42%
Book Value per Share2.571.691.740.940.042.711.8611.185.292.52
Total Shareholders' Equity175.69M123.28M142.39M86.94M3.44M461.14M399.67M222.36M117.35M68.5M
Common Stock72.22K74.06K90.36K97.23K101.36K186.85K217.38K21.09K22.79K36.1K
Retained Earnings-361.1M-434.84M-523.36M-620.43M-739.79M-906.2M-1.21B-1.49B-1.62B-1.73B
Treasury Stock0000000000
Accumulated OCI2.71M1.33M-117K-528.87K472.61K-256.15K-282.24K-698.74K-662.6K-675.67K
Minority Interest245.83K96.27K96.27K96.27K1.97M00000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-12.44M-62.56M-63.21M-73.55M-97.85M-177.98M-215.71M-216.22M-124.37M-104.08M
Operating CF Margin %-0.31%-1.77%-1.5%-2.41%-23.8%-24.01%-121.54%-21.07%-149.48%-477.95%
Operating CF Growth %0.58%-4.03%-0.01%-0.16%-0.33%-0.82%-0.21%-0%0.42%0.16%
Net Income-29.1M-73.74M-88.21M-96.97M-120.55M-167.47M-303.66M-279.82M-135.12M-107.25M
Depreciation & Amortization1.92M3.09M3.47M5M5.52M4.63M4.73M5.5M3.5M3.13M
Stock-Based Compensation6.19M10.48M13.07M10.65M10.9M15.65M26.34M22.56M11.07M6.6M
Deferred Taxes-2.08M-849-150.03K3.42M-260.82K37.93M04.03M-32.05K0
Other Non-Cash Items-3M-1.83M5.71M-360.8K10.09M2.36M6.53M11.69M6.47M-3.88M
Working Capital Changes13.64M-546.16K2.9M4.71M-3.54M-71.07M50.35M19.83M-10.26M-2.66M
Change in Receivables-4.53M-9.24M10.08M2.43M2.02M-17.02M11.03M-3.71M9.33M1.21M
Change in Inventory1.05M592.02K531.87K-963.92K935.79K-55.15M0000
Change in Payables6.59M7.28M2.68M601.26K-4.59M3.25M26.14M32.61M-45.99M-3.37M
Cash from Investing+-54.82M16.27M-27.83M42.42M-9.04M-58.8M-175.34M109.59M87.36M104.07M
Capital Expenditures-2.78M-3.94M-10.29M-2.09M-987.93K-1.52M-1.23M-969.15K-320.9K0
CapEx % of Revenue0.07%0.11%0.24%0.07%0.24%0.21%0.69%0.09%0.39%2.24%
Acquisitions----------
Investments----------
Other Investing1M2.2M1M-2.78T-987.93B-2.77M000-428.51K
Cash from Financing+84.35M7.79M95.69M31.04M105.4M465.28M211.5M81.84M5M51.48M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing2.45M1.49M1.34M1.81M-1.14M10.62M2.06M-1.11M-466.65K31.86M
Net Change in Cash----------
Free Cash Flow+-15.22M-66.49M-73.5M-75.64M-98.84M-179.5M-216.94M-217.18M-124.69M-104.56M
FCF Margin %-0.38%-1.88%-1.74%-2.48%-24.04%-24.22%-122.24%-21.16%-149.86%-480.19%
FCF Growth %0.51%-3.37%-0.11%-0.03%-0.31%-0.82%-0.21%-0%0.43%0.16%
FCF per Share-0.22-0.91-0.90-0.82-0.79-1.06-1.01-10.92-5.62-3.85
FCF Conversion (FCF/Net Income)0.43x0.85x0.72x0.76x0.82x1.07x0.71x0.77x0.92x0.97x
Interest Paid000004.62M1.08M1.07M00
Taxes Paid00002.72M4.62M1.08M1.07M00

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-20.31%-49.27%-66.35%-84.5%-258.25%-71.34%-70.55%-89.97%-79.55%-115.42%
Return on Invested Capital (ROIC)-27.17%-51.39%-56.28%-77.53%-114.11%-56.03%-73.95%-70.46%-63.25%-114.07%
Gross Margin100%100%100%100%100%100%100%100%100%100%
Net Margin-71.94%-208.49%-208.92%-318.12%-2902.75%-2245.39%-17109.87%-2726.67%-16239.87%-49254.27%
Debt / Equity----18.41x0.08x0.08x0.14x0.26x0.17x
Interest Coverage--547.48x-3225.35x--13.98x-14.26x-155.55x-213.38x-117.71x-632.05x
FCF Conversion0.43x0.85x0.72x0.76x0.82x1.07x0.71x0.77x0.92x0.97x
Revenue Growth288%-12.83%19.37%-27.8%-86.51%80.24%-76.05%478.23%-91.89%-73.83%

Revenue by Segment

20182019202020212024
Reportables----217.76K
Reportables Growth-----
License29.86M3.64M5.17M902.26K-
License Growth--87.82%42.17%-82.55%-
Other Revenue--786.9K627.19K-
Other Revenue Growth----20.30%-
License with Affiliated Entities449.52K235.65K1.45M245.31K-
License with Affiliated Entities Growth--47.58%516.90%-83.13%-
Other Revenue Affiliated Entity-----
Other Revenue Affiliated Entity Growth-----
Grant171.59K237.54K---
Grant Growth-38.43%---
Grant with Affiliated Revenue-1.8K---
Grant with Affiliated Revenue Growth-----

Frequently Asked Questions

Growth & Financials

Inovio Pharmaceuticals, Inc. (INO) reported $0.2M in revenue for fiscal year 2024. This represents a 98% decrease from $9.8M in 2011.

Inovio Pharmaceuticals, Inc. (INO) saw revenue decline by 73.8% over the past year.

Inovio Pharmaceuticals, Inc. (INO) reported a net loss of $108.1M for fiscal year 2024.

Dividend & Returns

Inovio Pharmaceuticals, Inc. (INO) has a return on equity (ROE) of -115.4%. Negative ROE indicates the company is unprofitable.

Inovio Pharmaceuticals, Inc. (INO) had negative free cash flow of $20.88B in fiscal year 2024, likely due to heavy capital investments.

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