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Lyell Immunopharma, Inc. (LYEL) 10-Year Financial Performance & Capital Metrics

LYEL • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsImmuno-Oncology
AboutLyell Immunopharma, Inc., a T cell reprogramming company, engages in developing T cell therapies for patients with solid tumors. The company develops therapies using technology platforms, such as Gen-R, an ex vivo genetic reprogramming technology to overcome T cell exhaustion; and Epi-R, an ex vivo epigenetic reprogramming technology to generate population of T cells with durable stemness. Its pipeline includes LYL797, a T cell product candidate for the treatment of non-small cell lung cancer and triple negative breast cancers; LYL845, that targets multiple solid tumors; and NY-ESO-1 for synovial sarcoma and other solid tumor indications. The company entered into research and development collaboration and license agreement with GlaxoSmithKline for NY-ESO-1 program. Lyell Immunopharma, Inc. was incorporated in 2018 and is headquartered in South San Francisco, California.Show more
  • Revenue $61K -53.1%
  • EBITDA -$339M -49.6%
  • Net Income -$343M -46.2%
  • EPS (Diluted) -1.31 -40.1%
  • Gross Margin 100%
  • EBITDA Margin -555940.98% -218.7%
  • Operating Margin -588122.95% -209.5%
  • Net Margin -562285.25% -211.5%
  • ROE -66.1% -109.6%
  • ROIC -59.22% -115.8%
  • Debt/Equity 0.15 +59.7%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 94 (top 6%)

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Sales declining 37.8% over 5 years
  • ✗Trading more than 30% below 52-week high
  • ✗Expensive at 15.7x book value

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-37.83%
3Y-82.11%
TTM-34.92%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-59.65%

EPS CAGR

10Y-
5Y-
3Y-
TTM-642.69%

ROCE

10Y Avg-30.57%
5Y Avg-32.86%
3Y Avg-37.24%
Latest-62.25%

Peer Comparison

Immuno-Oncology
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
IMTXImmatics N.V.1.33B9.9270.86188.6%-136.72%-27.81%0.03
CTMXCytomX Therapeutics, Inc.720.1M4.2511.1836.45%24.66%26.09%
IOVAIovance Biotherapeutics, Inc.881.27M2.22-1.73136.99%-158.78%-56.62%0.08
REPLReplimune Group, Inc.572.64M7.30-2.38-117.82%0.18
NKTRNektar Therapeutics719.28M35.36-4.079.22%-192.87%-141.9%1.69
IMNMImmunome, Inc.2.52B22.85-4.57-35.5%-23.01%-84.4%0.03
IBRXImmunityBio, Inc.3.89B3.95-6.3722.71%-422.28%
NRIXNurix Therapeutics, Inc.1.91B18.86-6.55-29.15%-292.5%-65.76%0.05

Profit & Loss

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+657K7.76M10.65M84.68M130K61K
Revenue Growth %-10.81%0.37%6.95%-1%-0.53%
Cost of Goods Sold+000000
COGS % of Revenue------
Gross Profit+657K7.76M10.65M84.68M130K61K
Gross Margin %1%1%1%1%1%1%
Gross Profit Growth %-10.81%0.37%6.95%-1%-0.53%
Operating Expenses+102.75M219.69M225.43M271.74M247.14M358.82M
OpEx % of Revenue156.39%28.33%21.17%3.21%1901.06%5882.23%
Selling, General & Admin39.15M46.88M89.06M117.31M66.98M52.04M
SG&A % of Revenue59.59%6.04%8.36%1.39%515.25%853.13%
Research & Development63.59M182.24M138.69M159.19M182.94M171.6M
R&D % of Revenue96.8%23.5%13.02%1.88%1407.27%2813.16%
Other Operating Expenses0-9.43M-2.32M-4.75M-2.79M135.17M
Operating Income+-102.09M-211.94M-214.78M-187.06M-247.01M-358.75M
Operating Margin %-155.39%-27.33%-20.17%-2.21%-1900.06%-5881.23%
Operating Income Growth %--1.08%-0.01%0.13%-0.32%-0.45%
EBITDA+-100.83M-207.64M-201.15M-169.04M-226.76M-339.12M
EBITDA Margin %-153.47%-26.77%-18.89%-2%-1744.29%-5559.41%
EBITDA Growth %--1.06%0.03%0.16%-0.34%-0.5%
D&A (Non-Cash Add-back)1.26M4.29M13.62M18.02M20.25M19.63M
EBIT-102.09M-219.72M-214.78M-187.06M-247.01M-220.27M
Net Interest Income+8.12M5.94M1.17M7.05M23.45M24.07M
Interest Income8.12M5.94M1.17M7.05M23.45M24.07M
Interest Expense000000
Other Income/Expense-27.29M7.46M-35.44M3.94M12.38M15.76M
Pretax Income+-129.38M-204.47M-250.22M-183.12M-234.63M-342.99M
Pretax Margin %-196.92%-26.36%-23.49%-2.16%-1804.86%-5622.85%
Income Tax+000000
Effective Tax Rate %1%1%1%1%1%1%
Net Income+-129.38M-204.47M-250.22M-183.12M-234.63M-342.99M
Net Margin %-196.92%-26.36%-23.49%-2.16%-1804.86%-5622.85%
Net Income Growth %--0.58%-0.22%0.27%-0.28%-0.46%
Net Income (Continuing)-129.38M-204.47M-250.22M-183.12M-234.63M-342.99M
Discontinued Operations000000
Minority Interest000000
EPS (Diluted)+-0.53-0.84-1.03-0.74-0.93-1.31
EPS Growth %--0.59%-0.22%0.28%-0.26%-0.4%
EPS (Basic)-0.53-0.84-1.03-0.74-0.93-1.31
Diluted Shares Outstanding246.58M246.58M242.74M247.08M250.98M261.48M
Basic Shares Outstanding246.58M246.58M242.74M247.08M250.98M261.48M
Dividend Payout Ratio------

Balance Sheet

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+440.26M617.55M626.29M651.29M554.69M379.59M
Cash & Short-Term Investments436.05M612.62M614.79M640.15M546.22M370.53M
Cash Only96.67M140.41M293.83M123.55M145.65M105.6M
Short-Term Investments339.38M472.21M320.97M516.6M400.58M264.93M
Accounts Receivable000000
Days Sales Outstanding------
Inventory000000
Days Inventory Outstanding------
Other Current Assets00011.14M8.46M9.07M
Total Non-Current Assets+115.37M290.73M501.12M286.27M195.34M111.27M
Property, Plant & Equipment43.7M124.06M166.64M166.26M142.32M72.94M
Fixed Asset Turnover0.02x0.06x0.06x0.51x0.00x0.00x
Goodwill000000
Intangible Assets000000
Long-Term Investments68.98M163.44M330.53M115.04M48.51M32.01M
Other Non-Current Assets2.68M3.23M3.95M4.96M4.52M6.31M
Total Assets+555.63M908.28M1.13B937.56M750.03M490.86M
Asset Turnover0.00x0.01x0.01x0.09x0.00x0.00x
Asset Growth %-0.63%0.24%-0.17%-0.2%-0.35%
Total Current Liabilities+22.05M49.28M46.74M37.03M34.52M53.79M
Accounts Payable2.84M9.4M3.21M3.92M4.82M5.37M
Days Payables Outstanding------
Short-Term Debt000000
Deferred Revenue (Current)1000K1000K1000K000
Other Current Liabilities10.58M15.33M28.25M22.16M8.79M22.72M
Current Ratio19.97x12.53x13.40x17.59x16.07x7.06x
Quick Ratio19.97x12.53x13.40x17.59x16.07x7.06x
Cash Conversion Cycle------
Total Non-Current Liabilities+125.53M140.56M150.88M67.28M60.56M54.25M
Long-Term Debt000000
Capital Lease Obligations27.13M50.96M66.65M63.17M56.89M50.99M
Deferred Tax Liabilities000000
Other Non-Current Liabilities0532K4.57M4.11M3.66M3.25M
Total Liabilities147.58M189.84M197.62M104.31M95.08M108.03M
Total Debt+27.47M54.57M67.82M67.7M63.17M58.97M
Net Debt-69.2M-85.83M-226.01M-55.85M-82.48M-46.63M
Debt / Equity0.07x0.08x0.07x0.08x0.10x0.15x
Debt / EBITDA------
Net Debt / EBITDA------
Interest Coverage------
Total Equity+408.06M718.44M929.79M833.25M654.95M382.82M
Equity Growth %-0.76%0.29%-0.1%-0.21%-0.42%
Book Value per Share1.652.913.833.372.611.46
Total Shareholders' Equity408.06M718.44M929.79M833.25M654.95M382.82M
Common Stock1K2K24K25K25K29K
Retained Earnings-129.67M-334.14M-584.36M-767.48M-1B-1.35B
Treasury Stock000000
Accumulated OCI454K256K-1.62M-7.6M-94K291K
Minority Interest000000

Cash Flow

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+39.47M-160.87M-126.25M-169.56M-163.69M-162.39M
Operating CF Margin %60.08%-20.74%-11.85%-2%-1259.18%-2662.2%
Operating CF Growth %--5.08%0.22%-0.34%0.03%0.01%
Net Income-129.38M-204.47M-250.22M-183.12M-234.63M-342.99M
Depreciation & Amortization1.26M4.29M13.62M16.47M20.25M19.63M
Stock-Based Compensation15.73M33.26M62.2M0033.14M
Deferred Taxes-1.52M039.51M000
Other Non-Cash Items42.57M6.38M4.62M79.11M47.27M130.94M
Working Capital Changes110.81M-336K4.01M-82.02M3.42M-3.12M
Change in Receivables000000
Change in Inventory000000
Change in Payables1.71M-278K91K667K1.46M-3.23M
Cash from Investing+-422.43M-273.52M-121.57M-11.54M184.05M122.42M
Capital Expenditures-16.05M-51.48M-65.5M-24.28M-2.69M-464K
CapEx % of Revenue24.42%6.64%6.15%0.29%20.66%7.61%
Acquisitions------
Investments------
Other Investing-610.84M0-673.47M000
Cash from Financing+351.16M476.79M401.24M10.63M1.74M1.33M
Debt Issued (Net)------
Equity Issued (Net)------
Dividends Paid000000
Share Repurchases------
Other Financing0373K9.44M-461K-457K-76K
Net Change in Cash------
Free Cash Flow+23.43M-212.35M-191.75M-193.83M-166.38M-162.86M
FCF Margin %35.66%-27.38%-18%-2.29%-1279.85%-2669.8%
FCF Growth %--10.06%0.1%-0.01%0.14%0.02%
FCF per Share0.10-0.86-0.79-0.78-0.66-0.62
FCF Conversion (FCF/Net Income)-0.31x0.79x0.50x0.93x0.70x0.47x
Interest Paid000000
Taxes Paid000000

Key Ratios

Metric201920202021202220232024
Return on Equity (ROE)-31.71%-36.3%-30.36%-20.77%-31.53%-66.1%
Return on Invested Capital (ROIC)--32.72%-24.11%-18.94%-27.45%-59.22%
Gross Margin100%100%100%100%100%100%
Net Margin-19692.09%-2636.31%-2349.47%-216.24%-180486.15%-562285.25%
Debt / Equity0.07x0.08x0.07x0.08x0.10x0.15x
FCF Conversion-0.31x0.79x0.50x0.93x0.70x0.47x
Revenue Growth-1080.52%37.31%695.15%-99.85%-53.08%

Revenue by Segment

2024
Reportable segment61K
Reportable segment Growth-

Frequently Asked Questions

Growth & Financials

Lyell Immunopharma, Inc. (LYEL) reported $0.0M in revenue for fiscal year 2024. This represents a 94% decrease from $0.7M in 2019.

Lyell Immunopharma, Inc. (LYEL) saw revenue decline by 53.1% over the past year.

Lyell Immunopharma, Inc. (LYEL) reported a net loss of $325.7M for fiscal year 2024.

Dividend & Returns

Lyell Immunopharma, Inc. (LYEL) has a return on equity (ROE) of -66.1%. Negative ROE indicates the company is unprofitable.

Lyell Immunopharma, Inc. (LYEL) had negative free cash flow of $165.5M in fiscal year 2024, likely due to heavy capital investments.

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