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MAZEMaze Therapeutics, Inc.$24.09$1.3B
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MAZE logoMaze Therapeutics, Inc.(MAZE)Earnings, Financials & Key Ratios

MAZE•NASDAQ
Price updated Jun 11, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryMetabolic and Obesity Therapies
AboutMaze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of renal, cardiovascular, related metabolic diseases, and obesity in the United States. Its lead programs includes MZE829, an oral small molecule inhibitor of apolipoprotein L1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor of the solute transporter SLC6A19, which is in phase I clinical trial for the treatment of chronic kidney disease. Maze Therapeutics, Inc. was formerly known as Modulus Therapeutics, Inc. and changed its name to Maze Therapeutics, Inc. in September 2018. The company was incorporated in 2017 and is based in South San Francisco, California.Show more
  • Revenue$0-100.0%
  • EBITDA-$140M-330.8%
  • Net Income-$131M-351.0%
  • EPS (Diluted)-3.05-4020.3%
  • ROE-47.52%-194.1%
  • ROIC-99.35%-165.8%
  • Debt/Equity0.07-51.4%

MAZE Key Insights

Maze Therapeutics, Inc. (MAZE) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Healthy 5Y average net margin of 31.2%

✗Weaknesses

  • ✗Weak momentum: RS Rating 17 (bottom 17%)
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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MAZE Price & Volume

Maze Therapeutics, Inc. (MAZE) stock price & volume — 10-year historical chart

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MAZE Growth Metrics

Maze Therapeutics, Inc. (MAZE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-88.06%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-335.93%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-4396.88%

Return on Capital

10 Years-49.77%
5 Years-49.77%
3 Years-37.71%
Last Year-48.08%

MAZE Recent Earnings

Maze Therapeutics, Inc. (MAZE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/11 qtrs (50%)●Beat Revenue 1/11 qtrs (100%)
Q2 2026Latest
May 12, 2026
EPS
$0.45
Est $0.43
-4.7%
Revenue
$20M
Est $11M
+88.2%
Q2 2026
Mar 25, 2026
EPS
$0.65
Est $0.73
+11.0%
Revenue
—
Est $375,000
Q4 2025
Nov 6, 2025
EPS
$0.66
Est $0.74
+10.8%
Revenue
—
Q3 2025
Aug 12, 2025
EPS
$0.77
Est $0.79
+2.5%
Revenue
—
Est $3M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.45vs $0.43-4.7%
$20Mvs $11M+88.2%
Q2 2026Mar 25, 2026
$0.65vs $0.73+11.0%
—vs $375,000
Q4 2025Nov 6, 2025
$0.66vs $0.74+10.8%
—
Q3 2025Aug 12, 2025
$0.77vs $0.79+2.5%
—vs $3M
Based on last 11 quarters of dataView full earnings history →

MAZE Peer Comparison

Maze Therapeutics, Inc. (MAZE) competitors in Metabolic and Obesity Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
RARE logoRAREUltragenyx Pharmaceutical Inc.Direct Competitor2.36B23.98-4.1120.13%-91.03%-6.08%
FOLD logoFOLDAmicus Therapeutics, Inc.Direct Competitor4.55B14.49-164.8520.05%-4.27%-12.02%1.76
ACMR logoACMRACM Research, Inc.Direct Competitor6.07B91.7066.9315.24%9.48%5.13%0.16
BEAM logoBEAMBeam Therapeutics Inc.Direct Competitor3.02B29.41-36.31120.01%-49.17%-5.89%0.24
NTLA logoNTLAIntellia Therapeutics, Inc.Direct Competitor1.39B12.35-3.2416.92%-5.97%-57.27%0.14
ARWR logoARWRArrowhead Pharmaceuticals, Inc.Direct Competitor10.48B74.41-6099.18232.58%-48.38%-55.09%0.73
ALNY logoALNYAlnylam Pharmaceuticals, Inc.Product Competitor38.61B289.39124.2065.19%13.46%98.29%1.62
IONS logoIONSIonis Pharmaceuticals, Inc.Product Competitor12.2B73.82-31.0233.87%-30.87%-58.57%5.35

Compare MAZE vs Peers

Maze Therapeutics, Inc. (MAZE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RARE

Most directly comparable listed peer for MAZE.

Scale Benchmark

vs TMO

Larger-name benchmark to compare MAZE against a more recognizable public peer.

Peer Set

Compare Top 5

vs RARE, FOLD, ACMR, BEAM

MAZE Income Statement

Maze Therapeutics, Inc. (MAZE) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
00167.5M020M
Revenue Growth %
----100%-88.06%
Cost of Goods Sold
0002.4M1.59M
COGS % of Revenue
-----
Gross Profit
0▲ 0%
0▲ 0%
167.5M▲ 0%
-2.4M▼ 101.4%
18.41M▲ 0%
Gross Margin %
--100%-92.04%
Gross Profit Growth %
----101.43%-
Operating Expenses
111.03M98.55M109.91M140.5M152.46M
OpEx % of Revenue
--65.62%--
Selling, General & Admin
22.83M24.61M26.42M34.45M39.03M
SG&A % of Revenue
--15.77%--
Research & Development
88.19M73.94M83.5M108.45M114.57M
R&D % of Revenue
--49.85%--
Other Operating Expenses
000-2.4M-1.15M
Operating Income
-111.03M▲ 0%
-98.55M▲ 11.2%
57.59M▲ 158.4%
-142.9M▼ 348.1%
-134.05M▲ 0%
Operating Margin %
--34.38%--670.25%
Operating Income Growth %
-11.24%158.43%-348.15%-
EBITDA
-107.21M-94.46M60.88M-140.5M-131.89M
EBITDA Margin %
--36.35%--659.44%
EBITDA Growth %
-11.89%164.45%-330.76%-347.77%
D&A (Non-Cash Add-back)
3.82M4.09M3.3M2.4M2.16M
EBIT
-111.03M-98.55M57.59M-142.9M-128.38M
Net Interest Income
2.03M1.97M4.65M08.3M
Interest Income
2.03M1.97M4.65M09.16M
Interest Expense
0000866K
Other Income/Expense
-3.91M-1.86M-4.18M11.78M11.51M
Pretax Income
-114.94M▲ 0%
-100.42M▲ 12.6%
53.4M▲ 153.2%
-131.12M▼ 345.5%
-122.54M▲ 0%
Pretax Margin %
--31.88%--612.71%
Income Tax
001.17M00
Effective Tax Rate %
0%0%2.19%0%0%
Net Income
-114.94M▲ 0%
-100.42M▲ 12.6%
52.23M▲ 152.0%
-131.12M▼ 351.0%
-122.54M▲ 0%
Net Margin %
--31.18%--612.71%
Net Income Growth %
-12.64%152.02%-351.04%-335.93%
Net Income (Continuing)
-114.94M-100.42M52.23M-131.12M-122.54M
Discontinued Operations
00000
Minority Interest
00000
EPS (Diluted)
-2.63▲ 0%
-2.29▲ 12.6%
0.08▲ 103.4%
-3.05▼ 4020.3%
-2.27▲ 0%
EPS Growth %
-12.64%103.39%-4020.31%-4396.88%
EPS (Basic)
-2.63-2.290.08-3.05-
Diluted Shares Outstanding
43.78M43.78M43.8M42.98M53.9M
Basic Shares Outstanding
43.78M43.78M43.8M42.98M53.9M
Dividend Payout Ratio
-----

MAZE Balance Sheet

Maze Therapeutics, Inc. (MAZE) balance sheet — assets, liabilities & shareholders' equity

MetricDec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
106.15M34.11M201.67M349.72M379.78M
Cash & Short-Term Investments
99.92M29.16M196.81M341.92M352.38M
Cash Only
99.92M29.16M196.81M189.25M198.77M
Short-Term Investments
000152.67M153.62M
Accounts Receivable
000020M
Days Sales Outstanding
----94.44
Inventory
00000
Days Inventory Outstanding
-----
Other Current Assets
6.23M4.95M4.86M7.8M7.4M
Total Non-Current Assets
43.81M37.39M38.87M47.41M39.93M
Property, Plant & Equipment
41.23M34.98M29.92M25.16M23.97M
Fixed Asset Turnover
--5.60x-0.77x
Goodwill
00000
Intangible Assets
00000
Long-Term Investments
1.21M1.09M1.09M18.11M20.29M
Other Non-Current Assets
1.37M1.32M7.87M4.14M15.96M
Total Assets
149.96M▲ 0%
71.5M▼ 52.3%
240.54M▲ 236.4%
397.13M▲ 65.1%
419.71M▲ 0%
Asset Turnover
--0.70x-0.05x
Asset Growth %
--52.32%236.4%65.1%251.12%
Total Current Liabilities
20.78M16.32M20.67M22.56M21.24M
Accounts Payable
1.58M2.02M1.94M1.79M4.01M
Days Payables Outstanding
---272.5710.23
Short-Term Debt
00004.84M
Deferred Revenue (Current)
00000
Other Current Liabilities
7.49M2.93M6.02M10.85M12.38M
Current Ratio
5.11x2.09x9.76x15.50x17.88x
Quick Ratio
5.11x2.09x9.76x15.50x17.88x
Cash Conversion Cycle
-----615.78
Total Non-Current Liabilities
27.73M45.13M22.96M19.61M56.77M
Long-Term Debt
020.08M0038.83M
Capital Lease Obligations
27.73M25.05M22M18.51M75.77M
Deferred Tax Liabilities
00000
Other Non-Current Liabilities
00969K1.09M388K
Total Liabilities
48.51M61.45M43.64M42.16M78.01M
Total Debt
32.05M49.62M26.63M23.31M61.22M
Net Debt
-67.86M20.46M-170.18M-165.94M-137.54M
Debt / Equity
0.32x4.94x0.14x0.07x0.18x
Debt / EBITDA
--0.44x--0.46x
Net Debt / EBITDA
---2.80x-1.04x
Interest Coverage
-----148.24x
Total Equity
101.44M▲ 0%
10.05M▼ 90.1%
196.9M▲ 1858.5%
354.97M▲ 80.3%
341.7M▲ 0%
Equity Growth %
--90.09%1858.46%80.27%579.06%
Book Value per Share
2.320.234.508.266.34
Total Shareholders' Equity
101.44M10.05M196.9M354.97M341.7M
Common Stock
21K22K2K49K50K
Retained Earnings
-295.27M-395.69M-358.43M-489.55M-513.75M
Treasury Stock
00000
Accumulated OCI
000110K-135K
Minority Interest
00000

MAZE Cash Flow Statement

Maze Therapeutics, Inc. (MAZE) cash flow — operating, investing & free cash flow history

MetricDec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-99.2M-86.83M75.95M-111.94M-121.54M
Operating CF Margin %
--45.35%--
Operating CF Growth %
-12.48%187.48%-247.38%-182.93%
Net Income
-114.94M-100.42M52.23M-131.12M-122.54M
Depreciation & Amortization
3.82M4.09M3.3M2.4M2.16M
Stock-Based Compensation
6.74M8.75M9.65M16.4M13.17M
Deferred Taxes
00000
Other Non-Cash Items
8.42M7.07M12.3M2.65M8.23M
Working Capital Changes
-3.24M-6.32M-1.52M-2.27M-22.56M
Change in Receivables
0000-20M
Change in Inventory
00000
Change in Payables
-3.78M399K-204K-27K1.61M
Cash from Investing
-3.17M-441K-1.15M-170.96M-164.39M
Capital Expenditures
-1.97M-441K-1.15M-794K-588K
CapEx % of Revenue
--0.68%-2.94%
Acquisitions
-1.2M0000
Investments
-----
Other Investing
00000
Cash from Financing
1.73M16.39M92.85M275.34M190.32M
Debt Issued (Net)
016.18M24.48M038.52M
Equity Issued (Net)
1.73M209K68.37M275.84M-120.32M
Dividends Paid
00000
Share Repurchases
00000
Other Financing
000-500K272.12M
Net Change in Cash
-100.64M▲ 0%
-70.88M▲ 29.6%
167.65M▲ 336.5%
-7.57M▼ 104.5%
-95.61M▲ 0%
Free Cash Flow
-101.17M▲ 0%
-87.27M▲ 13.7%
74.81M▲ 185.7%
-112.73M▼ 250.7%
-122.13M▲ 0%
FCF Margin %
--44.66%--610.63%
FCF Growth %
-13.74%185.72%-250.7%-277.74%
FCF per Share
-2.31-1.991.71-2.62-2.27
FCF Conversion (FCF/Net Income)
0.86x0.86x1.45x0.85x1.00x
Interest Paid
00000
Taxes Paid
001.23M00

MAZE Key Ratios

Maze Therapeutics, Inc. (MAZE) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric202320242025TTM
Return on Equity (ROE)-180.12%50.48%-47.52%-36.63%
Return on Invested Capital (ROIC)-230.63%150.91%-99.35%-79.99%
Gross Margin-100%-92.04%
Net Margin-31.18%--612.71%
Debt / Equity4.94x0.14x0.07x0.18x
Interest Coverage----148.24x
FCF Conversion0.86x1.45x0.85x1.00x
Revenue Growth---100%-88.06%
Related:MAZE Dividend History·MAZE Revenue History·MAZE Price History·MAZE P/E History·MAZE Financial Ratios·MAZE Institutional Holders

MAZE SEC Filings & Documents

Maze Therapeutics, Inc. (MAZE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 22, 2026·SEC

Material company update

May 12, 2026·SEC

Material company update

Apr 22, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 25, 2026·SEC

FY 2025

Mar 31, 2025·SEC

10-Q Quarterly Reports

4
FY 2026

May 12, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 12, 2025·SEC

MAZE Frequently Asked Questions

Maze Therapeutics, Inc. (MAZE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Maze Therapeutics, Inc. (MAZE) reported $20.0M in revenue for fiscal year 2025.

Maze Therapeutics, Inc. (MAZE) saw revenue decline by 100.0% over the past year.

Maze Therapeutics, Inc. (MAZE) reported a net loss of $122.5M for fiscal year 2025.

Dividend & Returns

Maze Therapeutics, Inc. (MAZE) has a return on equity (ROE) of -47.5%. Negative ROE indicates the company is unprofitable.

Maze Therapeutics, Inc. (MAZE) had negative free cash flow of $122.1M in fiscal year 2025, likely due to heavy capital investments.

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