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Phio Pharmaceuticals Corp. (PHIO) 10-Year Financial Performance & Capital Metrics

PHIO • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsImmuno-Oncology
AboutPhio Pharmaceuticals Corp. develops immuno-oncology therapeutics in the United States. It offers INTASYL therapeutic platform focuses on targeting tumor and immune cells by regulating genes of the immune system. The company develops PH-762 that activates immune cells to recognize and kill cancer cells by reducing the expression of the checkpoint protein PD-1 for immunotherapy in adoptive cell transfer (ACT); PH-894 that silences the epigenetic protein BRD4, which is an intracellular regulator of gene expression for use in ACT; and PH-804 that targets the suppressive immune receptor TIGIT, which is a checkpoint protein present on T cells and natural killer cells for use in ACT. It has collaborations with AgonOx Inc. on clinical development of novel T cell-based cancer immunotherapies. The company was formerly known as RXi Pharmaceuticals Corporation and changed its name to Phio Pharmaceuticals Corp. in November 2018. Phio Pharmaceuticals Corp. was incorporated in 2011 and is headquartered in Marlborough, Massachusetts.Show more
  • Revenue $0
  • EBITDA -$7M +30.6%
  • Net Income -$7M +34.0%
  • EPS (Diluted) -0.91 +98.1%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -114.83% +1.5%
  • ROIC -
  • Debt/Equity -
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Weak momentum: RS Rating 8 (bottom 8%)
  • ✗Shares diluted 100.0% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-7.2%

EPS CAGR

10Y-
5Y-
3Y-
TTM-294107.81%

ROCE

10Y Avg-109.15%
5Y Avg-93.92%
3Y Avg-101.5%
Latest-118.64%

Peer Comparison

Immuno-Oncology
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
IMTXImmatics N.V.1.33B9.9270.86188.6%-136.72%-27.81%0.03
CTMXCytomX Therapeutics, Inc.720.1M4.2511.1836.45%24.66%26.09%
IOVAIovance Biotherapeutics, Inc.881.27M2.22-1.73136.99%-158.78%-56.62%0.08
REPLReplimune Group, Inc.572.64M7.30-2.38-117.82%0.18
NKTRNektar Therapeutics719.28M35.36-4.079.22%-192.87%-141.9%1.69
IMNMImmunome, Inc.2.52B22.85-4.57-35.5%-23.01%-84.4%0.03
IBRXImmunityBio, Inc.3.89B3.95-6.3722.71%-422.28%
NRIXNurix Therapeutics, Inc.1.91B18.86-6.55-29.15%-292.5%-65.76%0.05

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+34K19K15K138K21K00000
Revenue Growth %-0.52%-0.44%-0.21%8.2%-0.85%-1%----
Cost of Goods Sold+6.92M5.42M5.37M4.33M03.72M8.89M7.01M6.33M3.64M
COGS % of Revenue203.68%285%358%31.35%------
Gross Profit+-6.89M-5.4M-5.36M-4.19M21K-3.72M-8.89M-7.01M-6.33M-3.64M
Gross Margin %-202.68%-284%-357%-30.35%1%-----
Gross Profit Growth %-0.23%0.22%0.01%0.22%1.01%-177.95%-1.39%0.21%0.1%0.42%
Operating Expenses+10.27M9.03M9.38M7.5M9.01M5.08M4.63M4.45M4.49M3.74M
OpEx % of Revenue302.09%475.47%625.4%54.36%428.95%-----
Selling, General & Admin3.35M3.62M4.01M3.18M4.71M5.08M4.63M4.45M4.29M3.74M
SG&A % of Revenue98.41%190.47%267.4%23.01%224.19%-----
Research & Development6.92M5.42M5.37M4.33M4.3M3.72M8.89M7.01M6.33M3.64M
R&D % of Revenue203.68%285%358%31.35%204.76%-----
Other Operating Expenses2.44M3.11M4.7M4K0-3.72M-8.89M-7.01M-6.13M-3.64M
Operating Income+-10.24M-9.02M-14.06M-7.36M-8.99M-8.79M-13.51M-11.46M-10.82M-7.39M
Operating Margin %-301.09%-474.47%-937.47%-53.36%-427.95%-----
Operating Income Growth %-0.16%0.12%-0.56%0.48%-0.22%0.02%-0.54%0.15%0.06%0.32%
EBITDA+-10.16M-8.96M-13.99M-7.28M-8.92M-8.72M-13.44M-11.39M-10.64M-7.38M
EBITDA Margin %-298.82%-471.68%-932.8%-52.78%-424.76%-----
EBITDA Growth %-0.16%0.12%-0.56%0.48%-0.22%0.02%-0.54%0.15%0.07%0.31%
D&A (Non-Cash Add-back)77K53K70K81K67K72K75K71K184K2K
EBIT-10.24M-9.02M-14.07M-7.36M-8.99M-8.79M-13.51M-11.46M-10.83M-7.39M
Net Interest Income+16K15K-1K000000231K
Interest Income16K15K0000000231K
Interest Expense001K0000000
Other Income/Expense14K21K-11K4K79K-1K224K-18K-2K237K
Pretax Income+-10.22M-8.99M-14.07M-7.36M-8.91M-8.79M-13.29M-11.48M-10.83M-7.15M
Pretax Margin %-300.68%-473.37%-938.2%-53.33%-424.19%-----
Income Tax+-91K-74K-1.62M4K000000
Effective Tax Rate %1%1%0.88%1%1%1%1%1%1%1%
Net Income+-10.22M-8.99M-12.45M-7.36M-8.91M-8.79M-13.29M-11.48M-10.83M-7.15M
Net Margin %-300.68%-473.37%-830.13%-53.33%-424.19%-----
Net Income Growth %-0.16%0.12%-0.38%0.41%-0.21%0.01%-0.51%0.14%0.06%0.34%
Net Income (Continuing)-10.22M-8.99M-12.45M-7.36M-8.91M-8.79M-13.29M-11.48M-10.83M-7.15M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-93029.39-79282.81-32801.22-6218.35-2074.18-207.25-111.32-89.61-46.76-0.91
EPS Growth %0.61%0.15%0.59%0.81%0.67%0.9%0.46%0.2%0.48%0.98%
EPS (Basic)-93029.39-79282.81-32801.22-6218.35-2074.18-207.25-111.32-89.61-46.87-0.91
Diluted Shares Outstanding1101133801.18K4.26K42.43K118.68K126.16K231.51K7.87M
Basic Shares Outstanding1101133801.18K4.26K42.43K118.68K126.16K231K7.87M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+10.98M13.11M3.83M15.15M7.3M15.16M24.73M12.45M9.32M5.74M
Cash & Short-Term Investments10.62M12.91M3.58M14.88M6.93M14.24M24.06M11.78M8.49M5.38M
Cash Only5.12M12.91M3.58M14.88M6.93M14.24M24.06M11.78M8.49M5.38M
Short-Term Investments5.5M000000000
Accounts Receivable0000000000
Days Sales Outstanding----------
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets50K50K50K50K50K50K50K50K832K354K
Total Non-Current Assets+181K291K266K172K739K575K443K368K42K2K
Property, Plant & Equipment163K114K248K172K721K557K416K344K39K2K
Fixed Asset Turnover0.21x0.17x0.06x0.80x0.03x-----
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments0154.5K00000000
Other Non-Current Assets18K22.5K18K018K18K27K24K3K0
Total Assets+11.16M13.4M4.1M15.32M8.04M15.74M25.17M12.81M9.36M5.74M
Asset Turnover0.00x0.00x0.00x0.01x0.00x-----
Asset Growth %0.21%0.2%-0.69%2.74%-0.48%0.96%0.6%-0.49%-0.27%-0.39%
Total Current Liabilities+2.27M2.54M2.27M1.74M1.88M2.2M3.07M1.94M1.63M1.01M
Accounts Payable1.16M917K511K550K809K728K283K779K657K253K
Days Payables Outstanding61.361.8134.7346.41-71.5111.6240.5537.8725.35
Short-Term Debt0000000000
Deferred Revenue (Current)0000000000
Other Current Liabilities0000551K722K019K720K731K
Current Ratio4.84x5.16x1.69x8.69x3.88x6.91x8.06x6.42x5.71x5.65x
Quick Ratio4.84x5.16x1.69x8.69x3.88x6.91x8.06x6.42x5.71x5.65x
Cash Conversion Cycle----------
Total Non-Current Liabilities+0000411K526K170K35K00
Long-Term Debt00000231K0000
Capital Lease Obligations0000411K295K170K35K00
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities0000000000
Total Liabilities2.27M2.54M2.27M1.74M2.29M2.72M3.24M1.97M1.63M1.01M
Total Debt+0000518K642K295K170K35K0
Net Debt-5.12M-12.91M-3.58M-14.88M-6.42M-13.6M-23.76M-11.61M-8.46M-5.38M
Debt / Equity----0.09x0.05x0.01x0.02x0.00x-
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage---14062.00x-------
Total Equity+8.89M10.86M1.83M13.58M5.75M13.02M21.93M10.84M7.73M4.72M
Equity Growth %2.24%0.22%-0.83%6.41%-0.58%1.26%0.68%-0.51%-0.29%-0.39%
Book Value per Share80899.0895687.664828.5111471.851348.54306.77184.7985.9233.390.60
Total Shareholders' Equity8.89M10.86M1.83M13.58M5.75M13.02M21.93M10.84M7.73M4.72M
Common Stock7K1K02K1K1K0000
Retained Earnings-57.1M-66.1M-78.55M-85.91M-94.82M-103.61M-116.9M-128.38M-139.21M-146.36M
Treasury Stock0000000000
Accumulated OCI-778K-831K-900K-981K000000
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-7.32M-7.76M-9.51M-7.52M-8.64M-8.8M-11.86M-12.13M-10.75M-7.11M
Operating CF Margin %-215.21%-408.42%-634.27%-54.49%-411.67%-----
Operating CF Growth %0.06%-0.06%-0.23%0.21%-0.15%-0.02%-0.35%-0.02%0.11%0.34%
Net Income-10.22M-8.99M-12.45M-7.36M-8.91M-8.79M-13.29M-11.48M-10.83M-7.15M
Depreciation & Amortization77K53K70K81K67K72K75K193K184K35K
Stock-Based Compensation1.53M756K314K282K300K136K480K414K303K147K
Deferred Taxes00-1.62M000-233K000
Other Non-Cash Items228K-9K4.71M405K109K111K117K0126K-6K
Working Capital Changes1.07M434K-530K-523K-213K-327K990K-1.26M-536K-138K
Change in Receivables0000000000
Change in Inventory0000000000
Change in Payables878K-246K-608K39K259K-81K-445K496K-122K-404K
Cash from Investing+-5.56M5.35M-103K-5K-72K-19K-51K-121K-5K8K
Capital Expenditures-57K-4K-203K-5K-72K-19K-51K-121K-5K-1K
CapEx % of Revenue1.68%0.21%13.53%0.04%3.43%-----
Acquisitions----------
Investments----------
Other Investing-5.5K-150K100K0000009K
Cash from Financing+9.49M10.2M292K18.82M772K16.13M21.72M-26K7.41M4M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid-209K000000000
Share Repurchases----------
Other Financing9.7M00069K3.85M2.15M-28K-26K-5K
Net Change in Cash----------
Free Cash Flow+-7.37M-7.76M-9.72M-7.53M-8.72M-8.82M-11.91M-12.25M-10.75M-7.11M
FCF Margin %-216.88%-408.63%-647.8%-54.53%-415.1%-----
FCF Growth %0.06%-0.05%-0.25%0.23%-0.16%-0.01%-0.35%-0.03%0.12%0.34%
FCF per Share-67103.47-68440.26-25596.65-6357.76-2045.09-207.89-100.34-97.10-46.45-0.90
FCF Conversion (FCF/Net Income)0.72x0.86x0.76x1.02x0.97x1.00x0.89x1.06x0.99x0.99x
Interest Paid0000000011K0
Taxes Paid0000000000

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-175.73%-91.1%-196.28%-95.52%-92.19%-93.73%-76.04%-70.06%-116.6%-114.83%
Return on Invested Capital (ROIC)-203.49%-785.28%--------
Gross Margin-20267.65%-28400%-35700%-3034.78%100%-----
Net Margin-30067.65%-47336.84%-83013.33%-5333.33%-42419.05%-----
Debt / Equity----0.09x0.05x0.01x0.02x0.00x-
Interest Coverage---14062.00x-------
FCF Conversion0.72x0.86x0.76x1.02x0.97x1.00x0.89x1.06x0.99x0.99x
Revenue Growth-52.11%-44.12%-21.05%820%-84.78%-100%----

Frequently Asked Questions

Growth & Financials

Phio Pharmaceuticals Corp. (PHIO) grew revenue by 0.0% over the past year. Growth has been modest.

Phio Pharmaceuticals Corp. (PHIO) reported a net loss of $8.0M for fiscal year 2024.

Dividend & Returns

Phio Pharmaceuticals Corp. (PHIO) has a return on equity (ROE) of -114.8%. Negative ROE indicates the company is unprofitable.

Phio Pharmaceuticals Corp. (PHIO) had negative free cash flow of $7.3M in fiscal year 2024, likely due to heavy capital investments.

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