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Senti Biosciences, Inc. (SNTI) 10-Year Financial Performance & Capital Metrics

SNTI • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsImmuno-Oncology
AboutSenti Biosciences, Inc. operates as a gene circuit company. The company develops cell and gene therapies engineered with gene circuits that are designed to reprogram cells with biological logic to sense inputs, compute decisions, and respond to respective cellular environments. Its synthetic biology platform utilizes off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cells to target particularly challenging liquid and solid tumor oncology indications. The company's lead programs include SENTI-202, a Logic Gated OR+NOT off-the-shelf CAR-NK cell therapy designed to target and eliminate acute myeloid leukemia (AML) cells, while sparing the healthy bone marrow; and SENTI-301, a multi-armed off-the-shelf CAR-NK cell therapy designed for the treatment of hepatocellular carcinoma (HCC). It also develops SENTI-401, a Logic Gated (NOT) off-the-shelf CAR-NK cell therapy designed to target and eliminate colorectal cancer (CRC) cells, while sparing healthy cells in the body. The company was founded in 2016 and is based in South San Francisco, California.Show more
  • Revenue $0 -100.0%
  • EBITDA -$55M +36.8%
  • Net Income -$53M +25.7%
  • EPS (Diluted) -11.49 +45.1%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -114.06% -55.8%
  • ROIC -114.93% -44.9%
  • Debt/Equity 1.31 +133.0%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Trading at only 0.2x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Weak momentum: RS Rating 6 (bottom 6%)
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM32.89%

EPS CAGR

10Y-
5Y-
3Y-
TTM71.42%

ROCE

10Y Avg-63.76%
5Y Avg-62.69%
3Y Avg-61.08%
Latest-63.75%

Peer Comparison

Immuno-Oncology
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
IMTXImmatics N.V.1.33B9.9270.86188.6%-136.72%-27.81%0.03
CTMXCytomX Therapeutics, Inc.720.1M4.2511.1836.45%24.66%26.09%
IOVAIovance Biotherapeutics, Inc.881.27M2.22-1.73136.99%-158.78%-56.62%0.08
REPLReplimune Group, Inc.572.64M7.30-2.38-117.82%0.18
NKTRNektar Therapeutics719.28M35.36-4.079.22%-192.87%-141.9%1.69
IMNMImmunome, Inc.2.52B22.85-4.57-35.5%-23.01%-84.4%0.03
IBRXImmunityBio, Inc.3.89B3.95-6.3722.71%-422.28%
NRIXNurix Therapeutics, Inc.1.91B18.86-6.55-29.15%-292.5%-65.76%0.05

Profit & Loss

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+85K394K2.29M3.29M1.98M0
Revenue Growth %-3.64%4.81%0.43%-0.4%-1%
Cost of Goods Sold+14.52M00000
COGS % of Revenue170.87%-----
Gross Profit+-14.44M394K2.29M3.29M1.98M0
Gross Margin %-169.87%1%1%1%1%-
Gross Profit Growth %-1.03%4.81%0.43%-0.4%-1%
Operating Expenses+7.39M25.09M42.74M65.37M94.7M61.04M
OpEx % of Revenue86.96%63.68%18.65%19.89%47.88%-
Selling, General & Admin7.34M9.3M21.25M37.63M34.87M23.51M
SG&A % of Revenue86.39%23.61%9.28%11.45%17.63%-
Research & Development14.52M15.96M21.96M28.14M32.15M34.36M
R&D % of Revenue170.87%40.5%9.58%8.57%16.25%-
Other Operating Expenses0-172K-470K-408K27.69M3.17M
Operating Income+-21.78M-24.69M-40.45M-62.08M-92.73M-61.04M
Operating Margin %-256.26%-62.68%-17.65%-18.89%-46.88%-
Operating Income Growth %--0.13%-0.64%-0.53%-0.49%0.34%
EBITDA+-21.36M-22.71M-37.44M-58.16M-87.3M-55.19M
EBITDA Margin %-251.24%-57.64%-16.34%-17.7%-44.13%-
EBITDA Growth %--0.06%-0.65%-0.55%-0.5%0.37%
D&A (Non-Cash Add-back)427K1.99M3.01M3.92M5.43M5.85M
EBIT-21.78M-24.69M-40.45M-62.08M-66.77M-60.73M
Net Interest Income+674K88K11K1.7M2.86M0
Interest Income674K88K11K1.7M2.86M0
Interest Expense000000
Other Income/Expense625K4.83M-14.87M12.42M9.32M8.25M
Pretax Income+-21.16M-19.86M-55.32M-49.66M-83.41M-52.79M
Pretax Margin %-248.91%-50.41%-24.15%-15.11%-42.17%-
Income Tax+000000
Effective Tax Rate %1%1%1%1.17%0.85%1%
Net Income+-21.16M-19.86M-55.32M-58.21M-71.06M-52.79M
Net Margin %-248.91%-50.41%-24.15%-17.71%-35.92%-
Net Income Growth %-0.06%-1.79%-0.05%-0.22%0.26%
Net Income (Continuing)-21.16M-19.86M-55.32M-49.66M-83.41M-52.79M
Discontinued Operations000-8.54M12.35M0
Minority Interest000000
EPS (Diluted)+-15.57-4.55-12.67-13.25-20.94-11.49
EPS Growth %-0.71%-1.78%-0.05%-0.58%0.45%
EPS (Basic)-15.57-4.55-12.67-13.25-20.94-11.49
Diluted Shares Outstanding1.36M4.37M4.37M4.39M4.44M4.6M
Basic Shares Outstanding1.36M4.37M4.37M4.39M4.44M4.6M
Dividend Payout Ratio------

Balance Sheet

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+18.76M31.71M58.75M102.58M71.2M58.96M
Cash & Short-Term Investments17.83M30.54M56.03M98.56M35.93M48.28M
Cash Only5.3M30.54M56.03M57.62M35.93M48.28M
Short-Term Investments12.53M0040.94M00
Accounts Receivable78K317K483K626K17.7M1.8M
Days Sales Outstanding334.94293.6776.9569.533.27K-
Inventory000000
Days Inventory Outstanding------
Other Current Assets853K830K1.43M1.52M237K584K
Total Non-Current Assets+16.59M16.64M37.95M78.21M48.28M38.88M
Property, Plant & Equipment16.59M16.14M33.08M74.55M41.61M35.24M
Fixed Asset Turnover0.01x0.02x0.07x0.04x0.05x-
Goodwill000000
Intangible Assets000000
Long-Term Investments003.26M3.37M4.64M0
Other Non-Current Assets-16.59M497K1.62M293K2.03M3.64M
Total Assets+35.84M48.34M96.7M180.79M119.48M97.84M
Asset Turnover0.00x0.01x0.02x0.02x0.02x-
Asset Growth %-0.35%1%0.87%-0.34%-0.18%
Total Current Liabilities+4.31M4.87M14.54M18.05M12.67M13.15M
Accounts Payable1.2M914K5.19M2.27M1.25M1.45M
Days Payables Outstanding30.08-----
Short-Term Debt001.74M000
Deferred Revenue (Current)001000K799K989K660K
Other Current Liabilities3.11M2.37M3.29M9.26M3.94M2.55M
Current Ratio4.36x6.52x4.04x5.68x5.62x4.49x
Quick Ratio4.36x6.52x4.04x5.68x5.62x4.49x
Cash Conversion Cycle------
Total Non-Current Liabilities+0102.19M21.78M35.48M39.9M59.05M
Long-Term Debt000000
Capital Lease Obligations012.53M20.99M35.1M33.54M28.89M
Deferred Tax Liabilities000000
Other Non-Current Liabilities089.66M619K373K6.36M30.16M
Total Liabilities17.88M107.06M36.33M53.53M52.57M72.19M
Total Debt+014.05M22.73M37.09M37.67M33.64M
Net Debt-5.3M-16.49M-33.3M-20.53M1.74M-14.64M
Debt / Equity--0.38x0.29x0.56x1.31x
Debt / EBITDA------
Net Debt / EBITDA------
Interest Coverage------
Total Equity+17.96M-58.71M60.38M127.26M66.91M25.65M
Equity Growth %--4.27%2.03%1.11%-0.47%-0.62%
Book Value per Share13.22-13.4513.8328.9615.085.58
Total Shareholders' Equity17.96M-58.71M60.38M127.26M66.91M25.65M
Common Stock1K1K04K5K1K
Retained Earnings-39.9M-59.76M-115.08M-173.29M-244.34M-297.13M
Treasury Stock000000
Accumulated OCI0001K00
Minority Interest000000

Cash Flow

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-18.38M-24.17M-34.63M-34.9M-52.4M-41.4M
Operating CF Margin %-216.21%-61.35%-15.12%-10.62%-26.49%-
Operating CF Growth %--0.32%-0.43%-0.01%-0.5%0.21%
Net Income-21.16M-19.86M-55.32M-58.22M-71.06M-52.79M
Depreciation & Amortization1.4M1.99M3.01M3.92M5.43M5.85M
Stock-Based Compensation205K272K2.29M16.39M9.67M1.75M
Deferred Taxes-329K00000
Other Non-Cash Items1.38M-4.79M14.76M-10.89M-1.1M-256K
Working Capital Changes124K-1.77M615K13.9M4.67M4.04M
Change in Receivables124K-10K-395K-131K-929K-727K
Change in Inventory000000
Change in Payables0-324K-617K186K-290K797K
Cash from Investing+3.75M11.36M-5.54M-81.96M30.08M34K
Capital Expenditures-2M-1.16M-5.54M-41.37M-12.04M-26K
CapEx % of Revenue23.48%2.95%2.42%12.59%6.09%-
Acquisitions------
Investments------
Other Investing5.75M000105K60K
Cash from Financing+14.01M38.05M68.44M118.55M779K53.73M
Debt Issued (Net)------
Equity Issued (Net)------
Dividends Paid000000
Share Repurchases------
Other Financing14.01M51K1.48M112.65M375K4.67M
Net Change in Cash------
Free Cash Flow+-20.37M-25.33M-40.18M-76.27M-64.43M-41.42M
FCF Margin %-239.69%-64.3%-17.54%-23.21%-32.57%-
FCF Growth %--0.24%-0.59%-0.9%0.16%0.36%
FCF per Share-15.00-5.80-9.20-17.35-14.52-9.01
FCF Conversion (FCF/Net Income)0.87x1.22x0.63x0.60x0.74x0.78x
Interest Paid000000
Taxes Paid000000

Key Ratios

Metric201920202021202220232024
Return on Equity (ROE)-117.77%--6652.92%-62.04%-73.19%-114.06%
Return on Invested Capital (ROIC)----69.6%-79.31%-114.93%
Gross Margin-16987.06%100%100%100%100%-
Net Margin-24890.59%-5041.12%-2414.62%-1771.45%-3592.42%-
Debt / Equity--0.38x0.29x0.56x1.31x
FCF Conversion0.87x1.22x0.63x0.60x0.74x0.78x
Revenue Growth-363.53%481.47%43.43%-39.81%-100%

Revenue by Segment

2022
License800K
License Growth-

Frequently Asked Questions

Growth & Financials

Senti Biosciences, Inc. (SNTI) saw revenue decline by 100.0% over the past year.

Senti Biosciences, Inc. (SNTI) reported a net loss of $47.6M for fiscal year 2024.

Dividend & Returns

Senti Biosciences, Inc. (SNTI) has a return on equity (ROE) of -114.1%. Negative ROE indicates the company is unprofitable.

Senti Biosciences, Inc. (SNTI) had negative free cash flow of $50.3M in fiscal year 2024, likely due to heavy capital investments.

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