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Wave Life Sciences Ltd. (WVE) 10-Year Financial Performance & Capital Metrics

WVE • • Industrial / General
HealthcareBiotechnologyRare Genetic DiseasesGene Therapy & Rare Diseases
AboutWave Life Sciences Ltd., a clinical stage genetic medicine company, designs, optimizes, and produces novel stereopure oligonucleotides through PRISM, a discovery and drug developing platform. It is developing oligonucleotides target ribonucleic acid to reduce the expression of disease-promoting proteins or restore the production of functional proteins, or modulate protein expression. The company also develops WVE-004, a C9orf72 molecule for the treatment of amyotrophic lateral sclerosis and frontotemporal dementia; WVE-003, a mutant huntingtin SNP3 molecule for the treatment of Huntington's disease; WVE-N531, an Exon 53 molecule for the treatment of Duchenne muscular dystrophy; and ATXN3, a discovery stage program for the treatment of spinocerebellar ataxia 3, as well as multiple preclinical programs for CNS disorders. In addition, it focuses on developing GalNAc-conjugated AIMers to treat hepatic indications comprising Alpha-1 antitrypsin deficiency (AATD); and two preclinical programs, such as Usher syndrome type 2A (USH2A) and retinitis pigmentosa due to a P23H mutation in the RHO gene (RhoP23H) for the treatment of retinal diseases. It has collaboration agreements with Pfizer Inc., Takeda Pharmaceutical Company Limited, University of Oxford, University of Massachusetts, Western Washington University, Grenoble Institute of Neurosciences, IRBM S.p.A, University of Louisville, and University College London. The company was incorporated in 2012 and is based in Singapore.Show more
  • Revenue $108M -4.4%
  • EBITDA -$102M -73.1%
  • Net Income -$97M -68.7%
  • EPS (Diluted) -0.70 -29.6%
  • Gross Margin 100%
  • EBITDA Margin -93.94% -81.1%
  • Operating Margin -101.94% -69.9%
  • Net Margin -89.57% -76.5%
  • ROE -77.87% +46.3%
  • ROIC -
  • Debt/Equity 0.12 -85.0%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 94 (top 6%)
  • ✓High quality earnings: Operating CF exceeds net income
  • ✓Strong 5Y sales CAGR of 46.6%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Shares diluted 30.3% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y46.62%
3Y38.28%
TTM103.75%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM14.43%

EPS CAGR

10Y-
5Y-
3Y-
TTM32.43%

ROCE

10Y Avg-82.54%
5Y Avg-95.74%
3Y Avg-99.9%
Latest-66.96%

Peer Comparison

Gene Therapy & Rare Diseases
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KRYSKrystal Biotech, Inc.8.47B291.9397.31473.02%53.3%17.48%1.41%0.01
BMRNBioMarin Pharmaceutical Inc.10.6B55.2024.9817.97%16.82%8.59%4.48%0.11
SRPTSarepta Therapeutics, Inc.2.25B21.469.1752.97%-11.25%-20.57%0.88
RAREUltragenyx Pharmaceutical Inc.2.33B24.11-3.8329.01%-91.95%-35.88%0.15
DYNDyne Therapeutics, Inc.2.81B17.04-5.06-61.26%0.04
TVTXTravere Therapeutics, Inc.2.6B29.11-7.1360.55%-20.32%-120.36%6.80
BEAMBeam Therapeutics Inc.3.51B34.55-7.54-83.18%-7.44%-42.92%0.22
SLNOSoleno Therapeutics, Inc.2.23B41.51-9.48-79.5%-15.85%0.22

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+152K1.49M3.7M14.41M15.98M20.08M40.96M3.65M113.31M108.3M
Revenue Growth %-8.77%1.49%2.89%0.11%0.26%1.04%-0.91%30.05%-0.04%
Cost of Goods Sold+9.06M393K79.31M134.43M175.43M130.94M0000
COGS % of Revenue59.59%0.26%21.41%9.33%10.98%6.52%----
Gross Profit+-8.9M1.09M-75.61M-120.01M-159.45M-110.87M40.96M3.65M113.31M108.3M
Gross Margin %-58.59%0.74%-20.41%-8.33%-9.98%-5.52%1%1%1%1%
Gross Profit Growth %-2.72%1.12%-70.24%-0.59%-0.33%0.3%1.37%-0.91%30.05%-0.04%
Operating Expenses+19.45M56.81M106.28M173.94M48.87M42.51M167.98M166.37M181.3M218.71M
OpEx % of Revenue127.96%38.26%28.69%12.07%3.06%2.12%4.1%45.59%1.6%2.02%
Selling, General & Admin10.39M15.99M26.98M39.51M48.87M42.51M46.1M50.51M51.29M59.02M
SG&A % of Revenue68.38%10.77%7.28%2.74%3.06%2.12%1.13%13.84%0.45%0.54%
Research & Development9.06M40.82M79.31M134.43M175.43M130.94M121.88M115.86M130.01M159.68M
R&D % of Revenue59.59%27.49%21.41%9.33%10.98%6.52%2.98%31.75%1.15%1.47%
Other Operating Expenses56K-50K-331K9.55M-175.43M-130.94M0000
Operating Income+-19.3M-55.33M-102.58M-159.52M-208.32M-153.38M-127.02M-162.72M-68M-110.4M
Operating Margin %-126.96%-37.26%-27.69%-11.07%-13.03%-7.64%-3.1%-44.59%-0.6%-1.02%
Operating Income Growth %-2.58%-1.87%-0.85%-0.56%-0.31%0.26%0.17%-0.28%0.58%-0.62%
EBITDA+-18.7M-54.54M-100.42M-153.94M-200.73M-145.26M-117.18M-152.61M-58.79M-101.74M
EBITDA Margin %-123.05%-36.73%-27.11%-10.68%-12.56%-7.24%-2.86%-41.82%-0.52%-0.94%
EBITDA Growth %-2.66%-1.92%-0.84%-0.53%-0.3%0.28%0.19%-0.3%0.61%-0.73%
D&A (Non-Cash Add-back)594K784K2.15M5.58M7.59M8.11M9.84M10.11M9.21M8.66M
EBIT-19.3M-55.72M-102.39M-159.52M-208.32M-153.38M-127.02M-162.72M-68M-110.4M
Net Interest Income+86K337K6K22K0-16K30K000
Interest Income0000-030K000
Interest Expense86K337K6K22K-16K-000
Other Income/Expense142K542K1.25M12.94M14.68M2.63M4.57M1.58M9.81M13.39M
Pretax Income+-19.16M-54.78M-101.33M-146.58M-193.64M-150.75M-122.45M-161.14M-58.19M-97.01M
Pretax Margin %-126.03%-36.89%-27.36%-10.17%-12.12%-7.51%-2.99%-44.16%-0.51%-0.9%
Income Tax+44K616K708K69K0-841K-204K681K-677K0
Effective Tax Rate %1%1.01%1.01%1%1%0.99%1%1%0.99%1%
Net Income+-19.2M-55.4M-102.03M-146.65M-193.64M-149.91M-122.25M-161.82M-57.51M-97.01M
Net Margin %-126.32%-37.31%-27.55%-10.17%-12.12%-7.47%-2.98%-44.35%-0.51%-0.9%
Net Income Growth %-2.67%-1.89%-0.84%-0.44%-0.32%0.23%0.18%-0.32%0.64%-0.69%
Net Income (Continuing)-19.2M-55.4M-101.98M-146.65M-193.64M-149.91M-122.25M-161.82M-57.51M-97.01M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-0.89-2.43-3.85-5.06-5.30-3.82-2.36-2.05-0.54-0.70
EPS Growth %-2.56%-1.73%-0.58%-0.31%-0.05%0.28%0.38%0.13%0.74%-0.3%
EPS (Basic)-0.89-2.43-3.85-5.06-5.30-3.82-2.36-2.05-0.54-0.70
Diluted Shares Outstanding21.55M22.8M26.51M28.97M33.87M39.23M51.83M78.86M106.1M138.28M
Basic Shares Outstanding21.55M22.8M26.51M28.97M33.87M39.23M51.83M78.86M106.1M138.28M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+161.38M151.99M150.49M202.27M185.48M230.04M162.56M98.54M235.37M320.39M
Cash & Short-Term Investments161.22M150.29M142.5M174.82M147.16M184.5M150.56M88.5M200.35M302.08M
Cash Only161.22M150.29M142.5M174.82M147.16M184.5M150.56M88.5M200.35M302.08M
Short-Term Investments0000000000
Accounts Receivable001M10M20M30M0021.09M1.42M
Days Sales Outstanding--98.54253.23456.74545.4--67.934.79
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets164K1.7M010.87M8.69M5.11M5.42M2.11M4.02M7.35M
Total Non-Current Assets+4.04M12.82M31.36M93.67M98.77M49.2M44.44M47.85M39.58M31.81M
Property, Plant & Equipment2.79M8.61M27.33M39.93M54.47M45.43M40.64M44.13M35.72M28M
Fixed Asset Turnover0.05x0.17x0.14x0.36x0.29x0.44x1.01x0.08x3.17x3.87x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments1.05M3.6M3.61M53.63M33.65M3.65M0000
Other Non-Current Assets1.06M3.65M411K111K10.66M115K3.8M3.72M3.85M3.81M
Total Assets+165.42M164.81M181.84M295.94M284.25M279.24M207.01M146.39M274.95M352.21M
Asset Turnover0.00x0.01x0.02x0.05x0.06x0.07x0.20x0.02x0.41x0.31x
Asset Growth %55.3%-0%0.1%0.63%-0.04%-0.02%-0.26%-0.29%0.88%0.28%
Total Current Liabilities+3.82M12.15M19.62M130.04M118.15M121.04M64.2M71.52M186.44M110.95M
Accounts Payable2.81M4.94M7.6M13.09M9.07M13.79M7.28M16.91M12.84M16.26M
Days Payables Outstanding113.284.59K34.9735.5418.8838.45----
Short-Term Debt62K62K01.16M3.24M3.71M0000
Deferred Revenue (Current)591K1000K1000K1000K1000K1000K1000K1000K1000K1000K
Other Current Liabilities291K3.38M1.33M6.47M7.52M2.97M10.18M12.29M14.06M15.36M
Current Ratio42.27x12.50x7.67x1.56x1.57x1.90x2.53x1.38x1.26x2.89x
Quick Ratio42.27x12.50x7.67x1.56x1.57x1.90x2.53x1.38x1.26x2.89x
Cash Conversion Cycle----------
Total Non-Current Liabilities+8.12M17.79M22.41M92.55M94.49M67.55M110.31M119.96M48.88M31.74M
Long-Term Debt003.09M9.25M000000
Capital Lease Obligations78K16K3.09M9.25M29.3M25.59M24.95M32.12M25.4M17.77M
Deferred Tax Liabilities78K16K1.37M68.16M000000
Other Non-Current Liabilities163K1.59M10.61M5.9M1.72M474K7.87M8.06M7.87M7.87M
Total Liabilities11.93M29.95M42.03M222.59M212.64M188.59M174.51M191.48M235.32M142.69M
Total Debt+140K78K3.45M10.4M32.55M29.3M29.92M37.61M32.12M25.4M
Net Debt-161.08M-150.22M-139.05M-164.42M-114.61M-155.19M-120.65M-50.88M-168.23M-276.67M
Debt / Equity0.00x0.00x0.02x0.14x0.45x0.32x0.92x-0.81x0.12x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage-224.40x-164.18x-17096.67x-7251.05x--9586.06x----
Total Equity+153.49M134.86M139.81M73.35M71.61M90.65M32.5M-45.09M39.63M209.51M
Equity Growth %74.72%-0.12%0.04%-0.48%-0.02%0.27%-0.64%-2.39%1.88%4.29%
Book Value per Share7.125.915.272.532.112.310.63-0.570.371.52
Total Shareholders' Equity153.49M134.86M139.81M73.35M71.61M90.65M32.5M-45.09M39.63M209.51M
Common Stock185.34M215.6M310.04M375.15M539.55M694.09M749.85M802.83M935.37M1.18B
Retained Earnings-35.08M-90.48M-192.51M-339.72M-533.36M-683.27M-805.51M-967.34M-1.02B-1.12B
Treasury Stock0000000000
Accumulated OCI41K-291K116K153K267K389K181K-29K-124K-262K
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-12.53M-31.87M-83.67M-22.86M-188.23M-115.98M-88.99M-127.78M-19.43M-151.03M
Operating CF Margin %-82.41%-21.46%-22.59%-1.59%-11.78%-5.78%-2.17%-35.02%-0.17%-1.39%
Operating CF Growth %-1.83%-1.54%-1.63%0.73%-7.23%0.38%0.23%-0.44%0.85%-6.77%
Net Income-19.2M-55.4M-102.03M-146.65M-193.64M-149.91M-122.25M-161.82M-57.51M-97.01M
Depreciation & Amortization594K784K2.15M5.58M9.2M9.98M9.84M10.11M9.21M8.66M
Stock-Based Compensation4.02M6.85M12.14M15.6M19.51M14.3M16.41M17.19M9.79M13.14M
Deferred Taxes36K-874K774K44K0-9.14M-12.64M000
Other Non-Cash Items88K565K3.59M183K09.14M12.64M12K00
Working Capital Changes1.93M16.21M-299K102.39M-23.3M9.65M7.01M6.72M19.08M-75.82M
Change in Receivables193K0-1M-59M10M20M30M0-21.09M19.66M
Change in Inventory242K00-4.08M04.61M2.04M000
Change in Payables1.65M3.37M3.89M4.94M-3.5M5.12M-6.57M9.35M-3.76M3.42M
Cash from Investing+-2.91M-8.16M-18.9M-9.94M-3.92M-1.34M-560K-1.25M-1.11M-938K
Capital Expenditures-1.86M-5.57M-18.89M-9.94M-3.92M-1.34M-560K-1.36M-1.11M-938K
CapEx % of Revenue12.22%3.75%5.1%0.69%0.25%0.07%0.01%0.37%0.01%0.01%
Acquisitions----------
Investments----------
Other Investing-1.05M-2.6M-9K-9.94M000106K00
Cash from Financing+175.59M29.12M94.37M65.09M164.4M154.54M55.83M67.19M132.53M253.89M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing112K-817K927K5.11M2.61M912K858K14.86M1.26M17.71M
Net Change in Cash----------
Free Cash Flow+-14.38M-37.44M-102.56M-32.8M-192.15M-117.32M-89.55M-129.14M-20.55M-151.96M
FCF Margin %-94.63%-25.21%-27.69%-2.28%-12.02%-5.84%-2.19%-35.39%-0.18%-1.4%
FCF Growth %-1.87%-1.6%-1.74%0.68%-4.86%0.39%0.24%-0.44%0.84%-6.4%
FCF per Share-0.67-1.64-3.87-1.13-5.67-2.99-1.73-1.64-0.19-1.10
FCF Conversion (FCF/Net Income)0.65x0.58x0.82x0.16x0.97x0.77x0.73x0.79x0.34x1.56x
Interest Paid029K37K0000000
Taxes Paid0554K11K0000000

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-24.69%-38.43%-74.29%-137.6%-267.17%-184.78%-198.53%--145.12%-77.87%
Return on Invested Capital (ROIC)---10056.86%-------
Gross Margin-5858.55%73.54%-2041.17%-832.62%-997.61%-552.21%100%100%100%100%
Net Margin-12631.58%-3730.71%-2754.72%-1017.43%-1211.52%-746.68%-298.42%-4434.72%-50.76%-89.57%
Debt / Equity0.00x0.00x0.02x0.14x0.45x0.32x0.92x-0.81x0.12x
Interest Coverage-224.40x-164.18x-17096.67x-7251.05x--9586.06x----
FCF Conversion0.65x0.58x0.82x0.16x0.97x0.77x0.73x0.79x0.34x1.56x
Revenue Growth-876.97%149.43%289.15%10.89%25.61%104.03%-91.09%3005.1%-4.42%

Frequently Asked Questions

Growth & Financials

Wave Life Sciences Ltd. (WVE) reported $109.2M in revenue for fiscal year 2024.

Wave Life Sciences Ltd. (WVE) saw revenue decline by 4.4% over the past year.

Wave Life Sciences Ltd. (WVE) reported a net loss of $121.9M for fiscal year 2024.

Dividend & Returns

Wave Life Sciences Ltd. (WVE) has a return on equity (ROE) of -77.9%. Negative ROE indicates the company is unprofitable.

Wave Life Sciences Ltd. (WVE) had negative free cash flow of $198.2M in fiscal year 2024, likely due to heavy capital investments.

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