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WVE logoWave Life Sciences Ltd.(WVE)Earnings, Financials & Key Ratios

WVE•NASDAQ
Price updated Jun 11, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryRNA and Genome Editing Developers
AboutWave Life Sciences Ltd., a clinical stage genetic medicine company, designs, optimizes, and produces novel stereopure oligonucleotides through PRISM, a discovery and drug developing platform. It is developing oligonucleotides target ribonucleic acid to reduce the expression of disease-promoting proteins or restore the production of functional proteins, or modulate protein expression. The company also develops WVE-004, a C9orf72 molecule for the treatment of amyotrophic lateral sclerosis and frontotemporal dementia; WVE-003, a mutant huntingtin SNP3 molecule for the treatment of Huntington's disease; WVE-N531, an Exon 53 molecule for the treatment of Duchenne muscular dystrophy; and ATXN3, a discovery stage program for the treatment of spinocerebellar ataxia 3, as well as multiple preclinical programs for CNS disorders. In addition, it focuses on developing GalNAc-conjugated AIMers to treat hepatic indications comprising Alpha-1 antitrypsin deficiency (AATD); and two preclinical programs, such as Usher syndrome type 2A (USH2A) and retinitis pigmentosa due to a P23H mutation in the RHO gene (RhoP23H) for the treatment of retinal diseases. It has collaboration agreements with Pfizer Inc., Takeda Pharmaceutical Company Limited, University of Oxford, University of Massachusetts, Western Washington University, Grenoble Institute of Neurosciences, IRBM S.p.A, University of Louisville, and University College London. The company was incorporated in 2012 and is based in Singapore.Show more
  • Revenue$43M-60.5%
  • EBITDA-$207M-103.0%
  • Net Income-$204M-110.7%
  • EPS (Diluted)-1.21-72.9%
  • Gross Margin79.28%-20.7%
  • EBITDA Margin-483.37%-414.6%
  • Operating Margin-504.09%-394.5%
  • Net Margin-478.33%-434.0%
  • ROE-55.56%+28.7%
  • Debt/Equity0.03-72.2%

WVE Key Insights

Wave Life Sciences Ltd. (WVE) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Strong 5Y sales CAGR of 16.3%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 15 (bottom 15%)
  • ✗Shares diluted 22.0% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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WVE Price & Volume

Wave Life Sciences Ltd. (WVE) stock price & volume — 10-year historical chart

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WVE Growth Metrics

Wave Life Sciences Ltd. (WVE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years75.75%
5 Years16.31%
3 Years127.08%
TTM-31.58%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-63.44%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-26.19%

Return on Capital

10 Years-85.67%
5 Years-87.8%
3 Years-68.37%
Last Year-54.9%

WVE Recent Earnings

Wave Life Sciences Ltd. (WVE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 6/12 qtrs (50%)
Q2 2026Latest
Apr 28, 2026
EPS
$0.13
Est $0.34
+61.8%
Revenue
$38M
Est $8M
+352.6%
Q1 2026
Feb 26, 2026
EPS
$0.30
Est $0.28
-7.1%
Revenue
$17M
Est $16M
+7.4%
Q4 2025
Nov 10, 2025
EPS
$0.32
Est $0.30
-6.7%
Revenue
$8M
Est $16M
-53.5%
Q3 2025
Jul 30, 2025
EPS
$0.31
Est $0.29
-6.9%
Revenue
$9M
Est $10M
-11.7%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestApr 28, 2026
$0.13vs $0.34+61.8%
$38Mvs $8M+352.6%
Q1 2026Feb 26, 2026
$0.30vs $0.28-7.1%
$17Mvs $16M+7.4%
Q4 2025Nov 10, 2025
$0.32vs $0.30-6.7%
$8Mvs $16M-53.5%
Q3 2025Jul 30, 2025
$0.31vs $0.29-6.9%
$9Mvs $10M-11.7%
Based on last 12 quarters of dataView full earnings history →

WVE Peer Comparison

Wave Life Sciences Ltd. (WVE) competitors in RNA and Genome Editing Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
SRPT logoSRPTSarepta Therapeutics, Inc.Direct Competitor1.58B15.00-2.1015.58%2.98%4.89%0.91
IONS logoIONSIonis Pharmaceuticals, Inc.Direct Competitor12.2B73.82-31.0233.87%-30.87%-58.57%5.35
ARWR logoARWRArrowhead Pharmaceuticals, Inc.Direct Competitor10.48B74.41-6099.18232.58%-48.38%-55.09%0.73
NTLA logoNTLAIntellia Therapeutics, Inc.Direct Competitor1.39B12.35-3.2416.92%-5.97%-57.27%0.14
BEAM logoBEAMBeam Therapeutics Inc.Direct Competitor3.02B29.41-36.31120.01%-49.17%-5.89%0.24
PRQR logoPRQRProQR Therapeutics N.V.Direct Competitor151.72M1.44-3.28-19.18%-339.41%-86.47%0.28
ALNY logoALNYAlnylam Pharmaceuticals, Inc.Product Competitor38.61B289.39124.2065.19%13.46%98.29%1.62
REGN logoREGNRegeneron Pharmaceuticals, Inc.Product Competitor63.53B611.4814.740.99%29.65%14.32%0.09

Compare WVE vs Peers

Wave Life Sciences Ltd. (WVE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for WVE.

Scale Benchmark

vs TMO

Larger-name benchmark to compare WVE against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, IONS, ARWR, NTLA

WVE Income Statement

Wave Life Sciences Ltd. (WVE) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
3.7M14.41M15.98M20.08M40.96M3.65M113.31M108.3M42.73M71.8M
Revenue Growth %
149.43%289.15%10.89%25.61%104.03%-91.09%3005.1%-4.42%-60.55%-31.58%
Cost of Goods Sold
79.31M134.43M175.43M130.94M00008.85M4.46M
COGS % of Revenue
2141.17%932.62%1097.61%652.21%----20.72%-
Gross Profit
-75.61M▲ 0%
-120.01M▼ 58.7%
-159.45M▼ 32.9%
-110.87M▲ 30.5%
40.96M▲ 136.9%
3.65M▼ 91.1%
113.31M▲ 3005.1%
108.3M▼ 4.4%
33.88M▼ 68.7%
67.34M▲ 0%
Gross Margin %
-2041.17%-832.62%-997.61%-552.21%100%100%100%100%79.28%93.79%
Gross Profit Growth %
-7023.53%-58.74%-32.86%30.47%136.95%-91.09%3005.1%-4.42%-68.72%-
Operating Expenses
106.28M173.94M48.87M42.51M167.98M166.37M181.3M218.71M249.26M264.22M
OpEx % of Revenue
2869.44%1206.72%305.76%211.73%410.07%4559.3%160.01%201.94%583.37%-
Selling, General & Admin
26.98M39.51M48.87M42.51M46.1M50.51M51.29M59.02M75.33M79.08M
SG&A % of Revenue
728.27%274.1%305.76%211.73%112.55%1384.3%45.27%54.5%176.31%-
Research & Development
79.31M134.43M175.43M130.94M121.88M115.86M130.01M159.68M182.78M189.6M
R&D % of Revenue
2141.17%932.62%1097.61%652.21%297.52%3175.01%114.74%147.44%427.78%-
Other Operating Expenses
-331K9.55M-175.43M-130.94M0000-8.85M-2M
Operating Income
-102.58M▲ 0%
-159.52M▼ 55.5%
-208.32M▼ 30.6%
-153.38M▲ 26.4%
-127.02M▲ 17.2%
-162.72M▼ 28.1%
-68M▲ 58.2%
-110.4M▼ 62.4%
-215.38M▼ 95.1%
-196.88M▲ 0%
Operating Margin %
-2769.44%-1106.72%-1303.37%-763.94%-310.07%-4459.3%-60.01%-101.94%-504.09%-274.21%
Operating Income Growth %
-85.41%-55.51%-30.59%26.37%17.19%-28.11%58.21%-62.37%-95.09%-
EBITDA
-100.42M-153.94M-200.73M-145.26M-117.18M-152.61M-58.79M-101.74M-206.53M-187.88M
EBITDA Margin %
-2711.26%-1068%-1255.89%-723.53%-286.06%-4182.13%-51.89%-93.94%-483.37%-261.68%
EBITDA Growth %
-84.12%-53.29%-30.39%27.63%19.33%-30.23%61.48%-73.06%-103%-60.45%
D&A (Non-Cash Add-back)
2.15M5.58M7.59M8.11M9.84M10.11M9.21M8.66M8.85M8.99M
EBIT
-102.39M-159.52M-208.32M-153.38M-127.02M-162.72M-68M-110.4M-204.38M-191.09M
Net Interest Income
6K22K0-16K30K00010.48M12.89M
Interest Income
00-030K00010.48M12.89M
Interest Expense
6K22K-16K000000
Other Income/Expense
1.25M12.94M14.68M2.63M4.57M1.58M9.81M13.39M11.01M13.29M
Pretax Income
-101.33M▲ 0%
-146.58M▼ 44.7%
-193.64M▼ 32.1%
-150.75M▲ 22.1%
-122.45M▲ 18.8%
-161.14M▼ 31.6%
-58.19M▲ 63.9%
-97.01M▼ 66.7%
-204.38M▼ 110.7%
-183.59M▲ 0%
Pretax Margin %
-2735.61%-1016.96%-1211.52%-750.86%-298.92%-4416.06%-51.36%-89.57%-478.33%-255.7%
Income Tax
708K69K0-841K-204K681K-677K000
Effective Tax Rate %
-0.7%-0.05%0%0.56%0.17%-0.42%1.16%0%0%0%
Net Income
-102.03M▲ 0%
-146.65M▼ 43.7%
-193.64M▼ 32.0%
-149.91M▲ 22.6%
-122.25M▲ 18.5%
-161.82M▼ 32.4%
-57.51M▲ 64.5%
-97.01M▼ 68.7%
-204.38M▼ 110.7%
-183.59M▲ 0%
Net Margin %
-2754.72%-1017.43%-1211.52%-746.68%-298.42%-4434.72%-50.76%-89.57%-478.33%-255.7%
Net Income Growth %
-84.18%-43.73%-32.04%22.58%18.45%-32.38%64.46%-68.67%-110.68%-63.44%
Net Income (Continuing)
-101.98M-146.65M-193.64M-149.91M-122.25M-161.82M-57.51M-97.01M-204.38M-183.59M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-3.85▲ 0%
-5.06▼ 31.4%
-5.30▼ 4.7%
-3.82▲ 27.9%
-2.36▲ 38.2%
-2.05▲ 13.1%
-0.54▲ 73.7%
-0.70▼ 29.6%
-1.21▼ 72.9%
-0.92▲ 0%
EPS Growth %
-58.44%-31.43%-4.74%27.92%38.22%13.14%73.66%-29.63%-72.86%-26.19%
EPS (Basic)
-3.85-5.06-5.30-3.82-2.36-2.05-0.54-0.70-1.21-
Diluted Shares Outstanding
26.51M28.97M33.87M39.23M51.83M78.86M106.1M138.28M168.65M200.17M
Basic Shares Outstanding
26.51M28.97M33.87M39.23M51.83M78.86M106.1M138.28M168.65M200.17M
Dividend Payout Ratio
----------

WVE Balance Sheet

Wave Life Sciences Ltd. (WVE) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
150.49M202.27M185.48M230.04M162.56M98.54M235.37M320.39M614.81M561.27M
Cash & Short-Term Investments
142.5M174.82M147.16M184.5M150.56M88.5M200.35M302.08M602.07M544.59M
Cash Only
142.5M174.82M147.16M184.5M150.56M88.5M200.35M302.08M602.07M544.59M
Short-Term Investments
0000000000
Accounts Receivable
1M10M20M30M0021.09M1.42M1.28M0
Days Sales Outstanding
98.54253.23456.74545.4--67.934.7910.916.39
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
010.87M8.69M5.11M5.42M2.11M4.02M7.35M11.47M16.68M
Total Non-Current Assets
31.36M93.67M98.77M49.2M44.44M47.85M39.58M31.81M23.68M22.27M
Property, Plant & Equipment
27.33M39.93M54.47M45.43M40.64M44.13M35.72M28M19.86M18.07M
Fixed Asset Turnover
0.14x0.36x0.29x0.44x1.01x0.08x3.17x3.87x2.15x3.41x
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
3.61M53.63M33.65M3.65M00003.81M7.62M
Other Non-Current Assets
411K111K10.66M115K3.8M3.72M3.85M3.81M16K386K
Total Assets
181.84M▲ 0%
295.94M▲ 62.7%
284.25M▼ 4.0%
279.24M▼ 1.8%
207.01M▼ 25.9%
146.39M▼ 29.3%
274.95M▲ 87.8%
352.21M▲ 28.1%
638.5M▲ 81.3%
583.54M▲ 0%
Asset Turnover
0.02x0.05x0.06x0.07x0.20x0.02x0.41x0.31x0.07x0.17x
Asset Growth %
10.33%62.74%-3.95%-1.76%-25.87%-29.28%87.82%28.1%81.29%171.84%
Total Current Liabilities
19.62M130.04M118.15M121.04M64.2M71.52M186.44M110.95M95.06M49.83M
Accounts Payable
7.6M13.09M9.07M13.79M7.28M16.91M12.84M16.26M15.7M19.06M
Days Payables Outstanding
34.9735.5418.8838.45----647.371.31K
Short-Term Debt
01.16M3.24M3.71M00008.36M8.33M
Deferred Revenue (Current)
2.71M100.94M89.65M91.56M37.1M31.56M150.06M65.97M44.44M151.94M
Other Current Liabilities
1.33M6.47M7.52M2.97M10.18M12.29M14.06M15.36M26.56M13.04M
Current Ratio
7.67x1.56x1.57x1.90x2.53x1.38x1.26x2.89x6.47x11.26x
Quick Ratio
7.67x1.56x1.57x1.90x2.53x1.38x1.26x2.89x6.47x11.26x
Cash Conversion Cycle
----------1.29K
Total Non-Current Liabilities
22.41M92.55M94.49M67.55M110.31M119.96M48.88M31.74M17.2M21.98M
Long-Term Debt
3.09M9.25M00000000
Capital Lease Obligations
3.09M9.25M29.3M25.59M24.95M32.12M25.4M17.77M9.4M41.74M
Deferred Tax Liabilities
1.37M68.16M00000000
Other Non-Current Liabilities
10.61M5.9M1.72M474K7.87M8.06M7.87M7.87M00
Total Liabilities
42.03M222.59M212.64M188.59M174.51M191.48M235.32M142.69M112.27M71.81M
Total Debt
3.45M10.4M32.55M29.3M29.92M37.61M32.12M25.4M17.77M15.71M
Net Debt
-139.05M-164.42M-114.61M-155.19M-120.65M-50.88M-168.23M-276.67M-584.3M-528.88M
Debt / Equity
0.02x0.14x0.45x0.32x0.92x-0.81x0.12x0.03x0.03x
Debt / EBITDA
----------0.08x
Net Debt / EBITDA
---------2.81x
Interest Coverage
-17065.17x-7251.05x--9586.06x------
Total Equity
139.81M▲ 0%
73.35M▼ 47.5%
71.61M▼ 2.4%
90.65M▲ 26.6%
32.5M▼ 64.2%
-45.09M▼ 238.8%
39.63M▲ 187.9%
209.51M▲ 428.7%
526.23M▲ 151.2%
511.73M▲ 0%
Equity Growth %
3.67%-47.54%-2.38%26.6%-64.15%-238.75%187.89%428.68%151.17%3399.62%
Book Value per Share
5.272.532.112.310.63-0.570.371.523.122.56
Total Shareholders' Equity
139.81M73.35M71.61M90.65M32.5M-45.09M39.63M209.51M526.23M511.73M
Common Stock
310.04M375.15M539.55M694.09M749.85M802.83M935.37M1.18B1.62B1.63B
Retained Earnings
-192.51M-339.72M-533.36M-683.27M-805.51M-967.34M-1.02B-1.12B-1.33B-1.35B
Treasury Stock
0000000000
Accumulated OCI
116K153K267K389K181K-29K-124K-262K-250K-254K
Minority Interest
0000000000

WVE Cash Flow Statement

Wave Life Sciences Ltd. (WVE) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-83.67M-22.86M-188.23M-115.98M-88.99M-127.78M-19.43M-151.03M-187.49M-182.35M
Operating CF Margin %
-2258.94%-158.61%-1177.7%-577.69%-217.25%-3501.81%-17.15%-139.45%-438.82%-
Operating CF Growth %
-162.52%72.68%-723.34%38.38%23.27%-43.59%84.79%-677.24%-24.15%-31.68%
Net Income
-102.03M-146.65M-193.64M-149.91M-122.25M-161.82M-57.51M-97.01M-204.38M-183.59M
Depreciation & Amortization
2.15M5.58M9.2M9.98M9.84M10.11M9.21M8.66M8.85M8.15M
Stock-Based Compensation
12.14M15.6M19.51M14.3M16.41M17.19M9.79M13.14M021.73M
Deferred Taxes
774K44K0-9.14M-12.64M00000
Other Non-Cash Items
3.59M183K09.14M12.64M12K0024.97M9.43M
Working Capital Changes
-299K102.39M-23.3M9.65M7.01M6.72M19.08M-75.82M-16.94M-38.08M
Change in Receivables
-1M-59M10M20M30M0-21.09M19.66M146K177.78K
Change in Inventory
0-4.08M04.61M2.04M00000
Change in Payables
3.89M4.94M-3.5M5.12M-6.57M9.35M-3.76M3.42M-561K4.81M
Cash from Investing
-18.9M-9.94M-3.92M-1.34M-560K-1.25M-1.11M-938K-718K-981.99K
Capital Expenditures
-18.89M-9.94M-3.92M-1.34M-560K-1.36M-1.11M-938K-718K-273K
CapEx % of Revenue
509.91%68.95%24.51%6.66%1.37%37.3%0.98%0.87%1.68%0.38%
Acquisitions
0000000000
Investments
----------
Other Investing
-9K-9.94M000106K000-708.99K
Cash from Financing
94.37M65.09M164.4M154.54M55.83M67.19M132.53M253.89M488.24M489.54M
Debt Issued (Net)
-62K-16K00000000
Equity Issued (Net)
93.51M60M161.79M153.63M54.97M52.33M131.28M236.18M488.24M486.47M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
927K5.11M2.61M912K858K14.86M1.26M17.71M03.07M
Net Change in Cash
-7.79M▲ 0%
32.33M▲ 515.0%
-27.64M▼ 185.5%
37.34M▲ 235.1%
-33.93M▼ 190.9%
-62.06M▼ 82.9%
111.89M▲ 280.3%
101.79M▼ 9.0%
300.04M▲ 194.8%
301.55M▲ 0%
Free Cash Flow
-102.56M▲ 0%
-32.8M▲ 68.0%
-192.15M▼ 485.8%
-117.32M▲ 38.9%
-89.55M▲ 23.7%
-129.14M▼ 44.2%
-20.55M▲ 84.1%
-151.96M▼ 639.6%
-187.49M▼ 23.4%
-183.34M▲ 0%
FCF Margin %
-2768.84%-227.56%-1202.21%-584.35%-218.61%-3539.11%-18.13%-140.31%-438.82%-255.35%
FCF Growth %
-173.93%68.02%-485.82%38.94%23.67%-44.21%84.09%-639.63%-23.38%-1.11%
FCF per Share
-3.87-1.13-5.67-2.99-1.73-1.64-0.19-1.10-1.11-0.92
FCF Conversion (FCF/Net Income)
0.82x0.16x0.97x0.77x0.73x0.79x0.34x1.56x0.92x1.00x
Interest Paid
37K000000000
Taxes Paid
11K000000000

WVE Key Ratios

Wave Life Sciences Ltd. (WVE) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)-74.29%-137.6%-267.17%-184.78%-198.53%--145.12%-77.87%-55.56%-56.41%
Return on Invested Capital (ROIC)-10056.86%--------338.24%
Gross Margin-2041.17%-832.62%-997.61%-552.21%100%100%100%100%79.28%93.79%
Net Margin-2754.72%-1017.43%-1211.52%-746.68%-298.42%-4434.72%-50.76%-89.57%-478.33%-255.7%
Debt / Equity0.02x0.14x0.45x0.32x0.92x-0.81x0.12x0.03x0.03x
Interest Coverage-17065.17x-7251.05x--9586.06x------
FCF Conversion0.82x0.16x0.97x0.77x0.73x0.79x0.34x1.56x0.92x1.00x
Revenue Growth149.43%289.15%10.89%25.61%104.03%-91.09%3005.1%-4.42%-60.55%-31.58%
Related:WVE Dividend History·WVE Revenue History·WVE Price History·WVE P/E History·WVE Financial Ratios·WVE Institutional Holders

WVE SEC Filings & Documents

Wave Life Sciences Ltd. (WVE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 28, 2026·SEC

Material company update

Apr 21, 2026·SEC

Material company update

Apr 15, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 4, 2025·SEC

FY 2024

Mar 6, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Apr 28, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Jul 30, 2025·SEC

WVE Frequently Asked Questions

Wave Life Sciences Ltd. (WVE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Wave Life Sciences Ltd. (WVE) reported $71.8M in revenue for fiscal year 2025.

Wave Life Sciences Ltd. (WVE) saw revenue decline by 60.5% over the past year.

Wave Life Sciences Ltd. (WVE) reported a net loss of $183.6M for fiscal year 2025.

Dividend & Returns

Wave Life Sciences Ltd. (WVE) has a return on equity (ROE) of -55.6%. Negative ROE indicates the company is unprofitable.

Wave Life Sciences Ltd. (WVE) had negative free cash flow of $183.3M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in WVE back in 2013?

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