| Name | Market Cap | Current Price | P/E Ratio | Revenue Growth 1Y | Net Margin | ROE | FCF Yield | Debt/Equity |
|---|---|---|---|---|---|---|---|---|
| KRYSKrystal Biotech, Inc. | 8.47B | 291.93 | 97.31 | 473.02% | 53.3% | 17.48% | 1.41% | 0.01 |
| BMRNBioMarin Pharmaceutical Inc. | 10.6B | 55.20 | 24.98 | 17.97% | 16.82% | 8.59% | 4.48% | 0.11 |
| SRPTSarepta Therapeutics, Inc. | 2.25B | 21.46 | 9.17 | 52.97% | -11.25% | -20.57% | 0.88 | |
| RAREUltragenyx Pharmaceutical Inc. | 2.33B | 24.11 | -3.83 | 29.01% | -91.95% | -35.88% | 0.15 | |
| DYNDyne Therapeutics, Inc. | 2.81B | 17.04 | -5.06 | -61.26% | 0.04 | |||
| TVTXTravere Therapeutics, Inc. | 2.6B | 29.11 | -7.13 | 60.55% | -20.32% | -120.36% | 6.80 | |
| BEAMBeam Therapeutics Inc. | 3.51B | 34.55 | -7.54 | -83.18% | -7.44% | -42.92% | 0.22 | |
| SLNOSoleno Therapeutics, Inc. | 2.23B | 41.51 | -9.48 | -79.5% | -15.85% | 0.22 |
| Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 152K | 1.49M | 3.7M | 14.41M | 15.98M | 20.08M | 40.96M | 3.65M | 113.31M | 108.3M |
| Revenue Growth % | - | 8.77% | 1.49% | 2.89% | 0.11% | 0.26% | 1.04% | -0.91% | 30.05% | -0.04% |
| Cost of Goods Sold | 9.06M | 393K | 79.31M | 134.43M | 175.43M | 130.94M | 0 | 0 | 0 | 0 |
| COGS % of Revenue | 59.59% | 0.26% | 21.41% | 9.33% | 10.98% | 6.52% | - | - | - | - |
| Gross Profit | -8.9M | 1.09M | -75.61M | -120.01M | -159.45M | -110.87M | 40.96M | 3.65M | 113.31M | 108.3M |
| Gross Margin % | -58.59% | 0.74% | -20.41% | -8.33% | -9.98% | -5.52% | 1% | 1% | 1% | 1% |
| Gross Profit Growth % | -2.72% | 1.12% | -70.24% | -0.59% | -0.33% | 0.3% | 1.37% | -0.91% | 30.05% | -0.04% |
| Operating Expenses | 19.45M | 56.81M | 106.28M | 173.94M | 48.87M | 42.51M | 167.98M | 166.37M | 181.3M | 218.71M |
| OpEx % of Revenue | 127.96% | 38.26% | 28.69% | 12.07% | 3.06% | 2.12% | 4.1% | 45.59% | 1.6% | 2.02% |
| Selling, General & Admin | 10.39M | 15.99M | 26.98M | 39.51M | 48.87M | 42.51M | 46.1M | 50.51M | 51.29M | 59.02M |
| SG&A % of Revenue | 68.38% | 10.77% | 7.28% | 2.74% | 3.06% | 2.12% | 1.13% | 13.84% | 0.45% | 0.54% |
| Research & Development | 9.06M | 40.82M | 79.31M | 134.43M | 175.43M | 130.94M | 121.88M | 115.86M | 130.01M | 159.68M |
| R&D % of Revenue | 59.59% | 27.49% | 21.41% | 9.33% | 10.98% | 6.52% | 2.98% | 31.75% | 1.15% | 1.47% |
| Other Operating Expenses | 56K | -50K | -331K | 9.55M | -175.43M | -130.94M | 0 | 0 | 0 | 0 |
| Operating Income | -19.3M | -55.33M | -102.58M | -159.52M | -208.32M | -153.38M | -127.02M | -162.72M | -68M | -110.4M |
| Operating Margin % | -126.96% | -37.26% | -27.69% | -11.07% | -13.03% | -7.64% | -3.1% | -44.59% | -0.6% | -1.02% |
| Operating Income Growth % | -2.58% | -1.87% | -0.85% | -0.56% | -0.31% | 0.26% | 0.17% | -0.28% | 0.58% | -0.62% |
| EBITDA | -18.7M | -54.54M | -100.42M | -153.94M | -200.73M | -145.26M | -117.18M | -152.61M | -58.79M | -101.74M |
| EBITDA Margin % | -123.05% | -36.73% | -27.11% | -10.68% | -12.56% | -7.24% | -2.86% | -41.82% | -0.52% | -0.94% |
| EBITDA Growth % | -2.66% | -1.92% | -0.84% | -0.53% | -0.3% | 0.28% | 0.19% | -0.3% | 0.61% | -0.73% |
| D&A (Non-Cash Add-back) | 594K | 784K | 2.15M | 5.58M | 7.59M | 8.11M | 9.84M | 10.11M | 9.21M | 8.66M |
| EBIT | -19.3M | -55.72M | -102.39M | -159.52M | -208.32M | -153.38M | -127.02M | -162.72M | -68M | -110.4M |
| Net Interest Income | 86K | 337K | 6K | 22K | 0 | -16K | 30K | 0 | 0 | 0 |
| Interest Income | 0 | 0 | 0 | 0 | - | 0 | 30K | 0 | 0 | 0 |
| Interest Expense | 86K | 337K | 6K | 22K | - | 16K | - | 0 | 0 | 0 |
| Other Income/Expense | 142K | 542K | 1.25M | 12.94M | 14.68M | 2.63M | 4.57M | 1.58M | 9.81M | 13.39M |
| Pretax Income | -19.16M | -54.78M | -101.33M | -146.58M | -193.64M | -150.75M | -122.45M | -161.14M | -58.19M | -97.01M |
| Pretax Margin % | -126.03% | -36.89% | -27.36% | -10.17% | -12.12% | -7.51% | -2.99% | -44.16% | -0.51% | -0.9% |
| Income Tax | 44K | 616K | 708K | 69K | 0 | -841K | -204K | 681K | -677K | 0 |
| Effective Tax Rate % | 1% | 1.01% | 1.01% | 1% | 1% | 0.99% | 1% | 1% | 0.99% | 1% |
| Net Income | -19.2M | -55.4M | -102.03M | -146.65M | -193.64M | -149.91M | -122.25M | -161.82M | -57.51M | -97.01M |
| Net Margin % | -126.32% | -37.31% | -27.55% | -10.17% | -12.12% | -7.47% | -2.98% | -44.35% | -0.51% | -0.9% |
| Net Income Growth % | -2.67% | -1.89% | -0.84% | -0.44% | -0.32% | 0.23% | 0.18% | -0.32% | 0.64% | -0.69% |
| Net Income (Continuing) | -19.2M | -55.4M | -101.98M | -146.65M | -193.64M | -149.91M | -122.25M | -161.82M | -57.51M | -97.01M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.89 | -2.43 | -3.85 | -5.06 | -5.30 | -3.82 | -2.36 | -2.05 | -0.54 | -0.70 |
| EPS Growth % | -2.56% | -1.73% | -0.58% | -0.31% | -0.05% | 0.28% | 0.38% | 0.13% | 0.74% | -0.3% |
| EPS (Basic) | -0.89 | -2.43 | -3.85 | -5.06 | -5.30 | -3.82 | -2.36 | -2.05 | -0.54 | -0.70 |
| Diluted Shares Outstanding | 21.55M | 22.8M | 26.51M | 28.97M | 33.87M | 39.23M | 51.83M | 78.86M | 106.1M | 138.28M |
| Basic Shares Outstanding | 21.55M | 22.8M | 26.51M | 28.97M | 33.87M | 39.23M | 51.83M | 78.86M | 106.1M | 138.28M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - |
| Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 161.38M | 151.99M | 150.49M | 202.27M | 185.48M | 230.04M | 162.56M | 98.54M | 235.37M | 320.39M |
| Cash & Short-Term Investments | 161.22M | 150.29M | 142.5M | 174.82M | 147.16M | 184.5M | 150.56M | 88.5M | 200.35M | 302.08M |
| Cash Only | 161.22M | 150.29M | 142.5M | 174.82M | 147.16M | 184.5M | 150.56M | 88.5M | 200.35M | 302.08M |
| Short-Term Investments | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accounts Receivable | 0 | 0 | 1M | 10M | 20M | 30M | 0 | 0 | 21.09M | 1.42M |
| Days Sales Outstanding | - | - | 98.54 | 253.23 | 456.74 | 545.4 | - | - | 67.93 | 4.79 |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | - | - |
| Other Current Assets | 164K | 1.7M | 0 | 10.87M | 8.69M | 5.11M | 5.42M | 2.11M | 4.02M | 7.35M |
| Total Non-Current Assets | 4.04M | 12.82M | 31.36M | 93.67M | 98.77M | 49.2M | 44.44M | 47.85M | 39.58M | 31.81M |
| Property, Plant & Equipment | 2.79M | 8.61M | 27.33M | 39.93M | 54.47M | 45.43M | 40.64M | 44.13M | 35.72M | 28M |
| Fixed Asset Turnover | 0.05x | 0.17x | 0.14x | 0.36x | 0.29x | 0.44x | 1.01x | 0.08x | 3.17x | 3.87x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 1.05M | 3.6M | 3.61M | 53.63M | 33.65M | 3.65M | 0 | 0 | 0 | 0 |
| Other Non-Current Assets | 1.06M | 3.65M | 411K | 111K | 10.66M | 115K | 3.8M | 3.72M | 3.85M | 3.81M |
| Total Assets | 165.42M | 164.81M | 181.84M | 295.94M | 284.25M | 279.24M | 207.01M | 146.39M | 274.95M | 352.21M |
| Asset Turnover | 0.00x | 0.01x | 0.02x | 0.05x | 0.06x | 0.07x | 0.20x | 0.02x | 0.41x | 0.31x |
| Asset Growth % | 55.3% | -0% | 0.1% | 0.63% | -0.04% | -0.02% | -0.26% | -0.29% | 0.88% | 0.28% |
| Total Current Liabilities | 3.82M | 12.15M | 19.62M | 130.04M | 118.15M | 121.04M | 64.2M | 71.52M | 186.44M | 110.95M |
| Accounts Payable | 2.81M | 4.94M | 7.6M | 13.09M | 9.07M | 13.79M | 7.28M | 16.91M | 12.84M | 16.26M |
| Days Payables Outstanding | 113.28 | 4.59K | 34.97 | 35.54 | 18.88 | 38.45 | - | - | - | - |
| Short-Term Debt | 62K | 62K | 0 | 1.16M | 3.24M | 3.71M | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | 591K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K |
| Other Current Liabilities | 291K | 3.38M | 1.33M | 6.47M | 7.52M | 2.97M | 10.18M | 12.29M | 14.06M | 15.36M |
| Current Ratio | 42.27x | 12.50x | 7.67x | 1.56x | 1.57x | 1.90x | 2.53x | 1.38x | 1.26x | 2.89x |
| Quick Ratio | 42.27x | 12.50x | 7.67x | 1.56x | 1.57x | 1.90x | 2.53x | 1.38x | 1.26x | 2.89x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 8.12M | 17.79M | 22.41M | 92.55M | 94.49M | 67.55M | 110.31M | 119.96M | 48.88M | 31.74M |
| Long-Term Debt | 0 | 0 | 3.09M | 9.25M | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 78K | 16K | 3.09M | 9.25M | 29.3M | 25.59M | 24.95M | 32.12M | 25.4M | 17.77M |
| Deferred Tax Liabilities | 78K | 16K | 1.37M | 68.16M | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 163K | 1.59M | 10.61M | 5.9M | 1.72M | 474K | 7.87M | 8.06M | 7.87M | 7.87M |
| Total Liabilities | 11.93M | 29.95M | 42.03M | 222.59M | 212.64M | 188.59M | 174.51M | 191.48M | 235.32M | 142.69M |
| Total Debt | 140K | 78K | 3.45M | 10.4M | 32.55M | 29.3M | 29.92M | 37.61M | 32.12M | 25.4M |
| Net Debt | -161.08M | -150.22M | -139.05M | -164.42M | -114.61M | -155.19M | -120.65M | -50.88M | -168.23M | -276.67M |
| Debt / Equity | 0.00x | 0.00x | 0.02x | 0.14x | 0.45x | 0.32x | 0.92x | - | 0.81x | 0.12x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | - | - |
| Interest Coverage | -224.40x | -164.18x | -17096.67x | -7251.05x | - | -9586.06x | - | - | - | - |
| Total Equity | 153.49M | 134.86M | 139.81M | 73.35M | 71.61M | 90.65M | 32.5M | -45.09M | 39.63M | 209.51M |
| Equity Growth % | 74.72% | -0.12% | 0.04% | -0.48% | -0.02% | 0.27% | -0.64% | -2.39% | 1.88% | 4.29% |
| Book Value per Share | 7.12 | 5.91 | 5.27 | 2.53 | 2.11 | 2.31 | 0.63 | -0.57 | 0.37 | 1.52 |
| Total Shareholders' Equity | 153.49M | 134.86M | 139.81M | 73.35M | 71.61M | 90.65M | 32.5M | -45.09M | 39.63M | 209.51M |
| Common Stock | 185.34M | 215.6M | 310.04M | 375.15M | 539.55M | 694.09M | 749.85M | 802.83M | 935.37M | 1.18B |
| Retained Earnings | -35.08M | -90.48M | -192.51M | -339.72M | -533.36M | -683.27M | -805.51M | -967.34M | -1.02B | -1.12B |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | 41K | -291K | 116K | 153K | 267K | 389K | 181K | -29K | -124K | -262K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -12.53M | -31.87M | -83.67M | -22.86M | -188.23M | -115.98M | -88.99M | -127.78M | -19.43M | -151.03M |
| Operating CF Margin % | -82.41% | -21.46% | -22.59% | -1.59% | -11.78% | -5.78% | -2.17% | -35.02% | -0.17% | -1.39% |
| Operating CF Growth % | -1.83% | -1.54% | -1.63% | 0.73% | -7.23% | 0.38% | 0.23% | -0.44% | 0.85% | -6.77% |
| Net Income | -19.2M | -55.4M | -102.03M | -146.65M | -193.64M | -149.91M | -122.25M | -161.82M | -57.51M | -97.01M |
| Depreciation & Amortization | 594K | 784K | 2.15M | 5.58M | 9.2M | 9.98M | 9.84M | 10.11M | 9.21M | 8.66M |
| Stock-Based Compensation | 4.02M | 6.85M | 12.14M | 15.6M | 19.51M | 14.3M | 16.41M | 17.19M | 9.79M | 13.14M |
| Deferred Taxes | 36K | -874K | 774K | 44K | 0 | -9.14M | -12.64M | 0 | 0 | 0 |
| Other Non-Cash Items | 88K | 565K | 3.59M | 183K | 0 | 9.14M | 12.64M | 12K | 0 | 0 |
| Working Capital Changes | 1.93M | 16.21M | -299K | 102.39M | -23.3M | 9.65M | 7.01M | 6.72M | 19.08M | -75.82M |
| Change in Receivables | 193K | 0 | -1M | -59M | 10M | 20M | 30M | 0 | -21.09M | 19.66M |
| Change in Inventory | 242K | 0 | 0 | -4.08M | 0 | 4.61M | 2.04M | 0 | 0 | 0 |
| Change in Payables | 1.65M | 3.37M | 3.89M | 4.94M | -3.5M | 5.12M | -6.57M | 9.35M | -3.76M | 3.42M |
| Cash from Investing | -2.91M | -8.16M | -18.9M | -9.94M | -3.92M | -1.34M | -560K | -1.25M | -1.11M | -938K |
| Capital Expenditures | -1.86M | -5.57M | -18.89M | -9.94M | -3.92M | -1.34M | -560K | -1.36M | -1.11M | -938K |
| CapEx % of Revenue | 12.22% | 3.75% | 5.1% | 0.69% | 0.25% | 0.07% | 0.01% | 0.37% | 0.01% | 0.01% |
| Acquisitions | - | - | - | - | - | - | - | - | - | - |
| Investments | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -1.05M | -2.6M | -9K | -9.94M | 0 | 0 | 0 | 106K | 0 | 0 |
| Cash from Financing | 175.59M | 29.12M | 94.37M | 65.09M | 164.4M | 154.54M | 55.83M | 67.19M | 132.53M | 253.89M |
| Debt Issued (Net) | - | - | - | - | - | - | - | - | - | - |
| Equity Issued (Net) | - | - | - | - | - | - | - | - | - | - |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | - | - | - | - | - | - | - | - | - | - |
| Other Financing | 112K | -817K | 927K | 5.11M | 2.61M | 912K | 858K | 14.86M | 1.26M | 17.71M |
| Net Change in Cash | - | - | - | - | - | - | - | - | - | - |
| Free Cash Flow | -14.38M | -37.44M | -102.56M | -32.8M | -192.15M | -117.32M | -89.55M | -129.14M | -20.55M | -151.96M |
| FCF Margin % | -94.63% | -25.21% | -27.69% | -2.28% | -12.02% | -5.84% | -2.19% | -35.39% | -0.18% | -1.4% |
| FCF Growth % | -1.87% | -1.6% | -1.74% | 0.68% | -4.86% | 0.39% | 0.24% | -0.44% | 0.84% | -6.4% |
| FCF per Share | -0.67 | -1.64 | -3.87 | -1.13 | -5.67 | -2.99 | -1.73 | -1.64 | -0.19 | -1.10 |
| FCF Conversion (FCF/Net Income) | 0.65x | 0.58x | 0.82x | 0.16x | 0.97x | 0.77x | 0.73x | 0.79x | 0.34x | 1.56x |
| Interest Paid | 0 | 29K | 37K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 554K | 11K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Metric | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -24.69% | -38.43% | -74.29% | -137.6% | -267.17% | -184.78% | -198.53% | - | -145.12% | -77.87% |
| Return on Invested Capital (ROIC) | - | - | -10056.86% | - | - | - | - | - | - | - |
| Gross Margin | -5858.55% | 73.54% | -2041.17% | -832.62% | -997.61% | -552.21% | 100% | 100% | 100% | 100% |
| Net Margin | -12631.58% | -3730.71% | -2754.72% | -1017.43% | -1211.52% | -746.68% | -298.42% | -4434.72% | -50.76% | -89.57% |
| Debt / Equity | 0.00x | 0.00x | 0.02x | 0.14x | 0.45x | 0.32x | 0.92x | - | 0.81x | 0.12x |
| Interest Coverage | -224.40x | -164.18x | -17096.67x | -7251.05x | - | -9586.06x | - | - | - | - |
| FCF Conversion | 0.65x | 0.58x | 0.82x | 0.16x | 0.97x | 0.77x | 0.73x | 0.79x | 0.34x | 1.56x |
| Revenue Growth | - | 876.97% | 149.43% | 289.15% | 10.89% | 25.61% | 104.03% | -91.09% | 3005.1% | -4.42% |
Wave Life Sciences Ltd. (WVE) reported $109.2M in revenue for fiscal year 2024.
Wave Life Sciences Ltd. (WVE) saw revenue decline by 4.4% over the past year.
Wave Life Sciences Ltd. (WVE) reported a net loss of $121.9M for fiscal year 2024.
Wave Life Sciences Ltd. (WVE) has a return on equity (ROE) of -77.9%. Negative ROE indicates the company is unprofitable.
Wave Life Sciences Ltd. (WVE) had negative free cash flow of $198.2M in fiscal year 2024, likely due to heavy capital investments.