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ALXOALX Oncology Holdings Inc.
$1.53$83M
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ALXO logoALX Oncology Holdings Inc.(ALXO)Earnings, Financials & Key Ratios

ALXO•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for patients fighting cancer. Its lead product candidate is ALX148, a CD47 blocking therapeutic that is in Phase 1b/2 clinical trial used for the treatment of myelodysplastic syndromes; and for the treatment of acute myeloid leukemia and non-Hodgkin's lymphoma, as well as a range of solid tumor indications, including head and neck squamous cell carcinoma, human epidermal growth factor receptor 2 (HER2) positive gastric/gastroesophageal junction carcinoma, HER2-expressing breast cancer, and other solid tumors. The company's pre-clinical products include ALTA-002, a SIRPa TRAAC that offers ways to engage the innate and adaptive immune response to cancer. ALX Oncology Holdings Inc. has a collaboration agreement with Merck for a Phase 2 trial evaluating ALX148 in combination with pembrolizumab with and without chemotherapy in patients with head and neck cancer; Zymeworks on a Phase 1 trial evaluating ALX148 with the HER2-targeting bispecific antibody zanidatamab in patients with HER2-expressing breast cancer and other solid tumors; and Tallac Therapeutics for the development, manufacturing and commercialization of a novel class of cancer immunotherapeutics. It also has a license agreement with Selexis SA and Crystal Bioscience, Inc. The company was founded in 2015 and is headquartered in South San Francisco, California.Show more
  • Revenue$0
  • EBITDA-$103M+27.0%
  • Net Income-$102M+24.6%
  • EPS (Diluted)-1.90+26.4%
  • ROE-145.7%-63.9%

ALXO Key Insights

ALX Oncology Holdings Inc. (ALXO) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Profits declining 17.3% over 5 years
  • ✗Weak Piotroski F-Score: 2/9
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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ALXO Price & Volume

ALX Oncology Holdings Inc. (ALXO) stock price & volume — 10-year historical chart

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ALXO Growth Metrics

ALX Oncology Holdings Inc. (ALXO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM31.65%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM33.2%

Return on Capital

10 Years-95.77%
5 Years-68.56%
3 Years-94.05%
Last Year-127.03%

ALXO Recent Earnings

ALX Oncology Holdings Inc. (ALXO) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)
Q2 2026Latest
May 8, 2026
Metric
Actual
Est
EPS
$0.17-13.3%
$0.15
Rev
—
—
Q1 2026
Feb 27, 2026
Metric
Actual
Est
EPS
$0.42-10.5%
$0.38
Rev
—
—
Q4 2025
Nov 7, 2025
Metric
Actual
Est
EPS
$0.41-10.8%
$0.37
Rev
—
—
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.49-6.5%
$0.46
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 8, 2026
$0.17vs $0.15-13.3%
—
Q1 2026Feb 27, 2026
$0.42vs $0.38-10.5%
—
Q4 2025Nov 7, 2025
$0.41vs $0.37-10.8%
—
Q3 2025Aug 12, 2025
$0.49vs $0.46-6.5%
—
Based on last 12 quarters of dataView full earnings history →

ALXO Peer Comparison

ALX Oncology Holdings Inc. (ALXO) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
FATE logoFATEFate Therapeutics, Inc.Direct Competitor243.61M2.09-1.82-51.24%-20.57%-58.89%0.38
IMVT logoIMVTImmunovant, Inc.Direct Competitor7.26B35.34-12.76-68.16%0.00
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.45B24.31-7.39-4.26%-156.36%-68.97%0.16
AGEN logoAGENAgenus Inc.Direct Competitor124.93M3.00-882.3510.37%52.16%
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.19B60.98-6.27-43.89%-284.18%-87%1.66
MGNX logoMGNXMacroGenics, Inc.Direct Competitor262.52M4.13-3.500.78%-44.79%-147.8%1.92
EXEL logoEXELExelixis, Inc.Product Competitor13.19B51.9118.676.98%35.08%40.21%0.08
HALO logoHALOHalozyme Therapeutics, Inc.Product Competitor8.13B68.5526.7837.55%23.13%126.27%43.89

Compare ALXO vs Peers

ALX Oncology Holdings Inc. (ALXO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs FATE

Most directly comparable listed peer for ALXO.

Scale Benchmark

vs AMGN

Larger-name benchmark to compare ALXO against a more recognizable public peer.

Peer Set

Compare Top 5

vs FATE, IMVT, RCUS, AGEN

ALXO Income Statement

ALX Oncology Holdings Inc. (ALXO) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
2.07M4.8M1.18M000000
Revenue Growth %
-132.03%-75.35%-100%-----
Cost of Goods Sold
1.88M4.36M1.07M00000150K
COGS % of Revenue
90.95%90.91%90.95%------
Gross Profit
187K▲ 0%
436K▲ 133.2%
107K▼ 75.5%
0▼ 100.0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
-150K▲ 0%
Gross Margin %
9.05%9.09%9.05%------
Gross Profit Growth %
-133.16%-75.46%-100%-----
Operating Expenses
13.87M19.62M43.77M83.56M127.44M170.28M142.47M104.02M91.02M
OpEx % of Revenue
671.07%409.07%3703.05%------
Selling, General & Admin
2.6M3.31M14.81M23.39M29.04M28.48M26.09M23.85M21.28M
SG&A % of Revenue
125.83%69.08%1252.88%------
Research & Development
11.27M16.31M28.96M60.17M98.4M141.79M116.37M77M66.71M
R&D % of Revenue
545.23%339.99%2450.17%------
Other Operating Expenses
-2K0000003.17M850K
Operating Income
-13.68M▲ 0%
-19.18M▼ 40.2%
-43.66M▼ 127.6%
-83.56M▼ 91.4%
-127.44M▼ 52.5%
-170.28M▼ 33.6%
-142.47M▲ 16.3%
-104.02M▲ 27.0%
-91.17M▲ 0%
Operating Margin %
-662.02%-399.98%-3693.99%------
Operating Income Growth %
--40.19%-127.61%-91.36%-52.52%-33.62%16.33%26.99%-
EBITDA
-13.25M-18.75M-43.46M-83.5M-127.09M-169.44M-141.59M-103.31M-90.52M
EBITDA Margin %
-641.17%-391.03%-3676.9%------
EBITDA Growth %
--41.51%-131.74%-92.14%-52.2%-33.32%16.43%27.03%33.27%
D&A (Non-Cash Add-back)
431K429K202K51K342K836K872K706K645K
EBIT
-13.69M-19.19M-43.66M-83.47M-123.18M-159.24M-133.12M-100.09M-88.71M
Net Interest Income
0-21K-811K-12.91K4.04M9.08M7.64M2.36M2.14M
Interest Income
000914.28M10.65M9.37M3.96M3.66M
Interest Expense
021K811K13K238K1.56M1.73M1.6M1.53M
Other Income/Expense
-2K-26K-1.84M71K4.02M9.47M7.62M2.33M2.3M
Pretax Income
-13.69M▲ 0%
-19.21M▼ 40.4%
-45.5M▼ 136.9%
-83.48M▼ 83.5%
-123.42M▼ 47.8%
-160.81M▼ 30.3%
-134.85M▲ 16.1%
-101.69M▲ 24.6%
-88.87M▲ 0%
Pretax Margin %
-662.12%-400.52%-3849.32%------
Income Tax
45K34K241K-21K64K0000
Effective Tax Rate %
-0.33%-0.18%-0.53%0.03%-0.05%0%0%0%0%
Net Income
-13.73M▲ 0%
-19.24M▼ 40.1%
-45.74M▼ 137.7%
-83.46M▼ 82.5%
-123.48M▼ 47.9%
-160.81M▼ 30.2%
-134.85M▲ 16.1%
-101.69M▲ 24.6%
-88.87M▲ 0%
Net Margin %
-664.3%-401.23%-3869.71%------
Net Income Growth %
--40.14%-137.7%-82.47%-47.95%-30.23%16.14%24.59%31.65%
Net Income (Continuing)
-13.73M-19.24M-45.74M-83.46M-123.48M-160.81M-134.85M-101.69M-88.87M
Discontinued Operations
000000000
Minority Interest
000000000
EPS (Diluted)
-0.63▲ 0%
-0.88▼ 39.7%
-1.28▼ 45.5%
-2.07▼ 61.7%
-3.03▼ 46.4%
-3.74▼ 23.4%
-2.58▲ 31.0%
-1.90▲ 26.4%
-1.64▲ 0%
EPS Growth %
--39.68%-45.45%-61.72%-46.38%-23.43%31.02%26.36%33.2%
EPS (Basic)
-0.63-0.88-1.28-2.07-3.03-3.74-2.58-1.90-
Diluted Shares Outstanding
21.95M21.95M39.84M40.31M40.7M42.99M52.17M53.66M54.28M
Basic Shares Outstanding
21.95M21.95M39.84M40.31M40.7M42.99M52.17M53.66M54.28M
Dividend Payout Ratio
---------

ALXO Balance Sheet

ALX Oncology Holdings Inc. (ALXO) balance sheet — assets, liabilities & shareholders' equity

MetricDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
10.21M9.81M435.99M367.02M270.97M188.66M134.35M50.73M145.56M
Cash & Short-Term Investments
8.26M9.02M434.22M363.67M266.21M182.74M127.76M44.79M140.32M
Cash Only
8.26M9.02M434.22M363.67M48.82M22.41M17.57M16.37M32.28M
Short-Term Investments
0000217.38M160.33M110.19M28.42M108.04M
Accounts Receivable
932K536K0000892K298K0
Days Sales Outstanding
164.5840.79-------
Inventory
000000000
Days Inventory Outstanding
---------
Other Current Assets
00004.76M5.92M5.7M5.64M5.24M
Total Non-Current Assets
956K867K62K13.16M35.52M53.89M13.42M8.32M32.76M
Property, Plant & Equipment
956K860K52K3.47M9.81M10.84M9.63M1.2M1.05M
Fixed Asset Turnover
2.16x5.58x22.73x-----0.00x
Goodwill
000000000
Intangible Assets
000000000
Long-Term Investments
000016.7M35.41M3.52M3.49M42.35M
Other Non-Current Assets
07K10K9.69M9.01M7.64M267K3.63M2.93M
Total Assets
11.16M▲ 0%
10.68M▼ 4.4%
436.05M▲ 3984.4%
380.18M▼ 12.8%
306.49M▼ 19.4%
242.55M▼ 20.9%
147.78M▼ 39.1%
59.05M▼ 60.0%
178.33M▲ 0%
Asset Turnover
0.19x0.45x0.00x-----0.00x
Asset Growth %
--4.37%3984.43%-12.81%-19.38%-20.86%-39.08%-60.04%-123.59%
Total Current Liabilities
1.87M4.98M6.2M15.29M28.32M36M18.5M24.55M20.18M
Accounts Payable
697K3.75M4K3.76M8.07M8.59M4.5M4.91M3.85M
Days Payables Outstanding
135.32313.771.36-----12.32K
Short-Term Debt
000000435K5.22M5.22M
Deferred Revenue (Current)
000000000
Other Current Liabilities
369K1.06M2.13M3.53M4.72M6.7M5.97M14.42M11.11M
Current Ratio
5.45x1.97x70.28x24.00x9.57x5.24x7.26x2.07x7.21x
Quick Ratio
5.45x1.97x70.28x24.00x9.57x5.24x7.26x2.07x7.21x
Cash Conversion Cycle
---------
Total Non-Current Liabilities
136K5.97M5K1.84M14.7M16.84M15.66M8.51M6.8M
Long-Term Debt
05.42M009.39M9.64M9.47M00
Capital Lease Obligations
000005.98M5.16M04.13M
Deferred Tax Liabilities
000000000
Other Non-Current Liabilities
0412K5K1.84M5.31M1.22M1.03M8.51M6.8M
Total Liabilities
2.01M10.95M6.21M17.13M43.02M52.84M34.16M33.06M26.98M
Total Debt
05.42M0742K10.43M17.2M16.98M5.22M5.22M
Net Debt
-8.26M-3.6M-434.22M-362.93M-38.39M-5.21M-589K-11.16M-27.07M
Debt / Equity
---0.00x0.04x0.09x0.15x0.20x0.03x
Debt / EBITDA
---------0.06x
Net Debt / EBITDA
--------0.30x
Interest Coverage
--913.71x-53.84x-6420.85x-517.56x-101.75x-76.99x-62.48x-58.09x
Total Equity
9.15M▲ 0%
-276K▼ 103.0%
429.85M▲ 155840.9%
363.05M▼ 15.5%
263.46M▼ 27.4%
189.71M▼ 28.0%
113.62M▼ 40.1%
25.98M▼ 77.1%
151.35M▲ 0%
Equity Growth %
--103.01%155840.94%-15.54%-27.43%-27.99%-40.11%-77.13%-132.54%
Book Value per Share
0.42-0.0110.799.016.474.412.180.482.79
Total Shareholders' Equity
9.15M-276K429.85M363.05M263.46M189.71M113.62M25.98M151.35M
Common Stock
3K3K40K41K41K50K53K54K135K
Retained Earnings
-53.54M-72.78M-118.52M-201.99M-325.47M-486.27M-621.12M-722.82M-740.74M
Treasury Stock
000000000
Accumulated OCI
-1.02M000-845K256K275K28K-245K
Minority Interest
000000000

ALXO Cash Flow Statement

ALX Oncology Holdings Inc. (ALXO) cash flow — operating, investing & free cash flow history

MetricDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-13.19M-14.25M-38.29M-68.1M-89.22M-130.36M-121.91M-84.14M-78.13M
Operating CF Margin %
-638.12%-297.1%-3239.34%------
Operating CF Growth %
--8.03%-168.71%-77.86%-31.02%-46.11%6.48%30.98%109.7%
Net Income
-13.73M-19.24M-45.74M-83.46M-123.48M-160.81M-134.85M-101.69M-88.87M
Depreciation & Amortization
431K429K202K51K342K836K872K706K645K
Stock-Based Compensation
269K297K5.44M13.91M23.84M26.27M27.09M12.58M7.36M
Deferred Taxes
000000000
Other Non-Cash Items
2.33M11K1.57M5.42M228K-4.96M-2.6M3.93M6.68M
Working Capital Changes
-159K4.26M247K-4.03M9.85M8.3M-12.43M336K-3.95M
Change in Receivables
-932K396K536K000000
Change in Inventory
000000000
Change in Payables
-269K2.98M-3.74M3.29M4.51M458K-4.02M421K-233K
Cash from Investing
-653K-353K610K-4.92M-235.42M44.66M86.26M82.59M-50.09M
Capital Expenditures
-653K-353K-31K-4.92M-1.43M-1.27M-447K-212K-202K
CapEx % of Revenue
31.59%7.36%2.62%------
Acquisitions
0000233.99K0000
Investments
---------
Other Investing
00641K0-233.99K0000
Cash from Financing
1K15.36M462.88M2.47M9.86M59.29M30.82M362K139.89M
Debt Issued (Net)
05.92M0-281K9.61M-388K-827K-1.36M-2.67M
Equity Issued (Net)
-6K9.43M472.94M2.75M903K58.89M31.64M1.73M142.56M
Dividends Paid
000000000
Share Repurchases
-6K00000000
Other Financing
7K10K-10.05M0-655K792K001K
Net Change in Cash
-13.84M▲ 0%
755K▲ 105.5%
425.2M▲ 56218.1%
-70.55M▼ 116.6%
-314.78M▼ 346.2%
-26.42M▲ 91.6%
-4.84M▲ 81.7%
-1.19M▲ 75.3%
11.67M▲ 0%
Free Cash Flow
-13.84M▲ 0%
-14.6M▼ 5.5%
-38.32M▼ 162.4%
-73.02M▼ 90.6%
-90.65M▼ 24.1%
-131.64M▼ 45.2%
-122.36M▲ 7.0%
-84.35M▲ 31.1%
-78.33M▲ 0%
FCF Margin %
-669.71%-304.46%-3241.96%------
FCF Growth %
--5.48%-162.43%-90.56%-24.14%-45.22%7.05%31.06%28.15%
FCF per Share
-0.63-0.67-0.96-1.81-2.23-3.06-2.35-1.57-1.44
FCF Conversion (FCF/Net Income)
0.96x0.74x0.84x0.82x0.72x0.81x0.90x0.83x0.88x
Interest Paid
00427K11K00000
Taxes Paid
0047K274K00000

ALXO Key Ratios

ALX Oncology Holdings Inc. (ALXO) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2019202020212022202320242025TTM
Return on Equity (ROE)
-433.45%-21.3%-21.05%-39.42%-70.97%-88.91%-145.7%-124.06%
Return on Invested Capital (ROIC)
---50537.3%-84.88%-62.36%-71.82%-122.04%-120.96%
Gross Margin
9.09%9.05%------
Net Margin
-401.23%-3869.71%------
Debt / Equity
--0.00x0.04x0.09x0.15x0.20x0.03x
Interest Coverage
-913.71x-53.84x-6420.85x-517.56x-101.75x-76.99x-62.48x-58.09x
FCF Conversion
0.74x0.84x0.82x0.72x0.81x0.90x0.83x0.88x
Revenue Growth
132.03%-75.35%-100%-----
Related:ALXO Dividend History·ALXO Revenue History·ALXO Price History·ALXO P/E History·ALXO Financial Ratios·ALXO Institutional Holders

ALXO SEC Filings & Documents

ALX Oncology Holdings Inc. (ALXO) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 8, 2026·SEC

Material company update

Apr 13, 2026·SEC

Material company update

Feb 27, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 9, 2026·SEC

FY 2025

Mar 6, 2025·SEC

FY 2024

Mar 7, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 8, 2026·SEC

FY 2025

Nov 7, 2025·SEC

FY 2025

Aug 12, 2025·SEC

ALXO Frequently Asked Questions

ALX Oncology Holdings Inc. (ALXO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

ALX Oncology Holdings Inc. (ALXO) grew revenue by 0.0% over the past year. Growth has been modest.

ALX Oncology Holdings Inc. (ALXO) reported a net loss of $88.9M for fiscal year 2025.

Dividend & Returns

ALX Oncology Holdings Inc. (ALXO) has a return on equity (ROE) of -145.7%. Negative ROE indicates the company is unprofitable.

ALX Oncology Holdings Inc. (ALXO) had negative free cash flow of $78.3M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ALXO back in 2018?

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