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ALX Oncology Holdings Inc. (ALXO) 10-Year Financial Performance & Capital Metrics

ALXO • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsImmuno-Oncology
AboutALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for patients fighting cancer. Its lead product candidate is ALX148, a CD47 blocking therapeutic that is in Phase 1b/2 clinical trial used for the treatment of myelodysplastic syndromes; and for the treatment of acute myeloid leukemia and non-Hodgkin's lymphoma, as well as a range of solid tumor indications, including head and neck squamous cell carcinoma, human epidermal growth factor receptor 2 (HER2) positive gastric/gastroesophageal junction carcinoma, HER2-expressing breast cancer, and other solid tumors. The company's pre-clinical products include ALTA-002, a SIRPa TRAAC that offers ways to engage the innate and adaptive immune response to cancer. ALX Oncology Holdings Inc. has a collaboration agreement with Merck for a Phase 2 trial evaluating ALX148 in combination with pembrolizumab with and without chemotherapy in patients with head and neck cancer; Zymeworks on a Phase 1 trial evaluating ALX148 with the HER2-targeting bispecific antibody zanidatamab in patients with HER2-expressing breast cancer and other solid tumors; and Tallac Therapeutics for the development, manufacturing and commercialization of a novel class of cancer immunotherapeutics. It also has a license agreement with Selexis SA and Crystal Bioscience, Inc. The company was founded in 2015 and is headquartered in South San Francisco, California.Show more
  • Revenue $0
  • EBITDA -$142M +16.4%
  • Net Income -$135M +16.1%
  • EPS (Diluted) -2.58 +31.0%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -88.91% -25.3%
  • ROIC -71.82% -15.2%
  • Debt/Equity 0.15 +64.8%
  • Interest Coverage -82.40 +24.3%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 94 (top 6%)
  • ✓Trading at only 0.6x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Shares diluted 21.4% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM28.55%

EPS CAGR

10Y-
5Y-
3Y-
TTM31.88%

ROCE

10Y Avg-91.31%
5Y Avg-47.16%
3Y Avg-64.91%
Latest-84.85%

Peer Comparison

Immuno-Oncology
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Size & Scale
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Per Share
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Quality & Returns
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Latest Quarter
Momentum & Returns
Total Return (DRIP)
Technical
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
IMTXImmatics N.V.1.33B9.9270.86188.6%-136.72%-27.81%0.03
CTMXCytomX Therapeutics, Inc.720.1M4.2511.1836.45%24.66%26.09%
IOVAIovance Biotherapeutics, Inc.881.27M2.22-1.73136.99%-158.78%-56.62%0.08
REPLReplimune Group, Inc.572.64M7.30-2.38-117.82%0.18
NKTRNektar Therapeutics719.28M35.36-4.079.22%-192.87%-141.9%1.69
IMNMImmunome, Inc.2.52B22.85-4.57-35.5%-23.01%-84.4%0.03
IBRXImmunityBio, Inc.3.89B3.95-6.3722.71%-422.28%
NRIXNurix Therapeutics, Inc.1.91B18.86-6.55-29.15%-292.5%-65.76%0.05

Profit & Loss

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+2.07M4.8M1.18M0000
Revenue Growth %-1.32%-0.75%-1%---
Cost of Goods Sold+1.88M4.36M1.07M0000
COGS % of Revenue0.91%0.91%0.91%----
Gross Profit+187K436K107K0000
Gross Margin %0.09%0.09%0.09%----
Gross Profit Growth %-1.33%-0.75%-1%---
Operating Expenses+13.87M19.62M43.77M83.56M127.44M170.28M142.47M
OpEx % of Revenue6.71%4.09%37.03%----
Selling, General & Admin2.6M3.31M14.81M23.39M29.04M28.48M26.09M
SG&A % of Revenue1.26%0.69%12.53%----
Research & Development11.27M16.31M28.96M60.17M98.4M141.79M116.37M
R&D % of Revenue5.45%3.4%24.5%----
Other Operating Expenses-2K000000
Operating Income+-13.68M-19.18M-43.66M-83.56M-127.44M-170.28M-142.47M
Operating Margin %-6.62%-4%-36.94%----
Operating Income Growth %--0.4%-1.28%-0.91%-0.53%-0.34%0.16%
EBITDA+-13.25M-18.75M-43.46M-83.5M-127.09M-169.44M-141.59M
EBITDA Margin %-6.41%-3.91%-36.77%----
EBITDA Growth %--0.42%-1.32%-0.92%-0.52%-0.33%0.16%
D&A (Non-Cash Add-back)431K429K202K51K342K836K872K
EBIT-13.69M-19.19M-43.66M-83.47M-123.18M-159.24M-133.12M
Net Interest Income+0-21K-811K-12.91K4.04M9.08M7.64M
Interest Income000914.28M10.65M9.37M
Interest Expense021K811K13K238K1.56M1.73M
Other Income/Expense-2K-26K-1.84M71K4.02M9.47M7.62M
Pretax Income+-13.69M-19.21M-45.5M-83.48M-123.42M-160.81M-134.85M
Pretax Margin %-6.62%-4.01%-38.49%----
Income Tax+45K34K241K-21K64K00
Effective Tax Rate %1%1%1.01%1%1%1%1%
Net Income+-13.73M-19.24M-45.74M-83.46M-123.48M-160.81M-134.85M
Net Margin %-6.64%-4.01%-38.7%----
Net Income Growth %--0.4%-1.38%-0.82%-0.48%-0.3%0.16%
Net Income (Continuing)-13.73M-19.24M-45.74M-83.46M-123.48M-160.81M-134.85M
Discontinued Operations0000000
Minority Interest0000000
EPS (Diluted)+-0.63-0.88-1.28-2.07-3.03-3.74-2.58
EPS Growth %--0.4%-0.45%-0.62%-0.46%-0.23%0.31%
EPS (Basic)-0.63-0.88-1.28-2.07-3.03-3.74-2.58
Diluted Shares Outstanding21.95M21.95M39.84M40.31M40.7M42.99M52.17M
Basic Shares Outstanding21.95M21.95M39.84M40.31M40.7M42.99M52.17M
Dividend Payout Ratio-------

Balance Sheet

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+10.21M9.81M435.99M367.02M270.97M188.66M134.35M
Cash & Short-Term Investments8.26M9.02M434.22M363.67M266.21M182.74M127.76M
Cash Only8.26M9.02M434.22M363.67M48.82M22.41M17.57M
Short-Term Investments0000217.38M160.33M110.19M
Accounts Receivable932K536K0000892K
Days Sales Outstanding164.5840.79-----
Inventory0000000
Days Inventory Outstanding-------
Other Current Assets00004.76M5.92M5.7M
Total Non-Current Assets+956K867K62K13.16M35.52M53.89M13.42M
Property, Plant & Equipment956K860K52K3.47M9.81M10.84M9.63M
Fixed Asset Turnover2.16x5.58x22.73x----
Goodwill0000000
Intangible Assets0000000
Long-Term Investments000016.7M35.41M3.52M
Other Non-Current Assets07K10K9.69M9.01M7.64M267K
Total Assets+11.16M10.68M436.05M380.18M306.49M242.55M147.78M
Asset Turnover0.19x0.45x0.00x----
Asset Growth %--0.04%39.84%-0.13%-0.19%-0.21%-0.39%
Total Current Liabilities+1.87M4.98M6.2M15.29M28.32M36M18.5M
Accounts Payable697K3.75M4K3.76M8.07M8.59M4.5M
Days Payables Outstanding135.32313.771.36----
Short-Term Debt000000435K
Deferred Revenue (Current)0000000
Other Current Liabilities369K1.06M2.13M3.53M4.72M6.7M5.97M
Current Ratio5.45x1.97x70.28x24.00x9.57x5.24x7.26x
Quick Ratio5.45x1.97x70.28x24.00x9.57x5.24x7.26x
Cash Conversion Cycle-------
Total Non-Current Liabilities+136K5.97M5K1.84M14.7M16.84M15.66M
Long-Term Debt05.42M009.39M9.64M9.47M
Capital Lease Obligations000005.98M5.16M
Deferred Tax Liabilities0000000
Other Non-Current Liabilities0412K5K1.84M5.31M1.22M1.03M
Total Liabilities2.01M10.95M6.21M17.13M43.02M52.84M34.16M
Total Debt+05.42M0742K10.43M17.2M16.98M
Net Debt-8.26M-3.6M-434.22M-362.93M-38.39M-5.21M-589K
Debt / Equity---0.00x0.04x0.09x0.15x
Debt / EBITDA-------
Net Debt / EBITDA-------
Interest Coverage--913.48x-53.84x-6427.31x-535.45x-108.80x-82.40x
Total Equity+9.15M-276K429.85M363.05M263.46M189.71M113.62M
Equity Growth %--1.03%1558.41%-0.16%-0.27%-0.28%-0.4%
Book Value per Share0.42-0.0110.799.016.474.412.18
Total Shareholders' Equity9.15M-276K429.85M363.05M263.46M189.71M113.62M
Common Stock3K3K40K41K41K50K53K
Retained Earnings-53.54M-72.78M-118.52M-201.99M-325.47M-486.27M-621.12M
Treasury Stock0000000
Accumulated OCI-1.02M000-845K256K275K
Minority Interest0000000

Cash Flow

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-13.19M-14.25M-38.29M-68.1M-89.22M-130.36M-121.91M
Operating CF Margin %-6.38%-2.97%-32.39%----
Operating CF Growth %--0.08%-1.69%-0.78%-0.31%-0.46%0.06%
Net Income-13.73M-19.24M-45.74M-83.46M-123.48M-160.81M-134.85M
Depreciation & Amortization431K429K202K51K342K836K872K
Stock-Based Compensation269K297K5.44M13.91M23.84M26.27M27.09M
Deferred Taxes0000000
Other Non-Cash Items2.33M11K1.57M5.42M228K-4.96M-2.6M
Working Capital Changes-159K4.26M247K-4.03M9.85M8.3M-12.43M
Change in Receivables-932K396K536K0000
Change in Inventory0000000
Change in Payables-269K2.98M-3.74M3.29M4.51M458K-4.02M
Cash from Investing+-653K-353K610K-4.92M-235.42M44.66M86.26M
Capital Expenditures-653K-353K-31K-4.92M-1.43M-1.27M-447K
CapEx % of Revenue0.32%0.07%0.03%----
Acquisitions-------
Investments-------
Other Investing00641K0-233.99K00
Cash from Financing+1K15.36M462.88M2.47M9.86M59.29M30.82M
Debt Issued (Net)-------
Equity Issued (Net)-------
Dividends Paid0000000
Share Repurchases-------
Other Financing7K10K-10.05M0-655K792K0
Net Change in Cash-------
Free Cash Flow+-13.84M-14.6M-38.32M-73.02M-90.65M-131.64M-122.36M
FCF Margin %-6.7%-3.04%-32.42%----
FCF Growth %--0.05%-1.62%-0.91%-0.24%-0.45%0.07%
FCF per Share-0.63-0.67-0.96-1.81-2.23-3.06-2.35
FCF Conversion (FCF/Net Income)0.96x0.74x0.84x0.82x0.72x0.81x0.90x
Interest Paid00427K11K000
Taxes Paid0047K274K000

Key Ratios

Metric2018201920202021202220232024
Return on Equity (ROE)-149.98%-433.45%-21.3%-21.05%-39.42%-70.97%-88.91%
Return on Invested Capital (ROIC)-1149.27%---50537.3%-84.88%-62.36%-71.82%
Gross Margin9.05%9.09%9.05%----
Net Margin-664.3%-401.23%-3869.71%----
Debt / Equity---0.00x0.04x0.09x0.15x
Interest Coverage--913.48x-53.84x-6427.31x-535.45x-108.80x-82.40x
FCF Conversion0.96x0.74x0.84x0.82x0.72x0.81x0.90x
Revenue Growth-132.03%-75.35%-100%---

Frequently Asked Questions

Growth & Financials

ALX Oncology Holdings Inc. (ALXO) grew revenue by 0.0% over the past year. Growth has been modest.

ALX Oncology Holdings Inc. (ALXO) reported a net loss of $108.0M for fiscal year 2024.

Dividend & Returns

ALX Oncology Holdings Inc. (ALXO) has a return on equity (ROE) of -88.9%. Negative ROE indicates the company is unprofitable.

ALX Oncology Holdings Inc. (ALXO) had negative free cash flow of $97.4M in fiscal year 2024, likely due to heavy capital investments.

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