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ASMB logoAssembly Biosciences, Inc.(ASMB)Earnings, Financials & Key Ratios

ASMB•NASDAQ
$31.36
$498M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutAssembly Biosciences, Inc., a clinical-stage biotechnology company, discovers and develops therapeutic candidates for the treatment of hepatitis B virus (HBV) infection in the United States. The company's lead product candidate is Vebicorvir, which as completed Phase 2 clinical trials to treat patients with chronic HBV infection. It is also developing ABI-H3733 that has completed Phase 1a clinical study, and ABI-4334, which is in pre-clinical trials for the treatment of HBV. The company has collaboration agreements with BeiGene, Ltd. and Arbutus Biopharma Corporation; and Antios Therapeutics, Inc. to evaluate a triple combination treatment in patients with chronic hepatitis B virus infection. It also has strategic license agreements with Indiana University Research and Technology Corporation; and Door Pharmaceuticals, LLC. The company was formerly known as Ventrus Biosciences, Inc. and changed its name to Assembly Biosciences, Inc. in June 2014. Assembly Biosciences, Inc. was incorporated in 2005 and is headquartered in South San Francisco, California.Show more
  • Revenue$72M+153.5%
  • EBITDA-$12M+73.5%
  • Net Income-$6M+84.8%
  • EPS (Diluted)-0.55+91.8%
  • Gross Margin99.82%-0.2%
  • EBITDA Margin-16.58%+89.6%
  • Operating Margin-16.76%+89.5%
  • Net Margin-8.47%+94.0%
  • ROE-5.1%+95.3%
  • ROIC-12.2%+96.1%
  • Debt/Equity0.01-86.3%
Technical→

ASMB Key Insights

Assembly Biosciences, Inc. (ASMB) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Strong 5Y profit CAGR of 37.1%
  • ✓High quality earnings: Operating CF exceeds net income

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 86.7% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

ASMB Price & Volume

Assembly Biosciences, Inc. (ASMB) stock price & volume — 10-year historical chart

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ASMB Growth Metrics

Assembly Biosciences, Inc. (ASMB) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-1.78%
3 Years-
TTM153.52%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM84.76%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM82.39%

Return on Capital

10 Years-45.35%
5 Years-53.29%
3 Years-44.34%
Last Year-8.65%

ASMB Recent Earnings

Assembly Biosciences, Inc. (ASMB) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 6/12 qtrs (86%)
Q2 2026Latest
Mar 19, 2026
EPS
$2.48
Est $0.51
+586.3%
Revenue
$42M
Est $7M
+472.2%
Q4 2025
Nov 10, 2025
EPS
$0.72
Est $0.50
-44.0%
Revenue
$11M
Est $7M
+44.6%
Q3 2025
Aug 6, 2025
EPS
$1.33
Est $0.65
-103.6%
Revenue
$10M
Est $9M
+3.2%
Q2 2025
May 8, 2025
EPS
$1.17
Est $2.01
+41.8%
Revenue
$9M
Est $7M
+27.0%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 19, 2026
$2.48vs $0.51+586.3%
$42Mvs $7M+472.2%
Q4 2025Nov 10, 2025
$0.72vs $0.50-44.0%
$11Mvs $7M+44.6%
Q3 2025Aug 6, 2025
$1.33vs $0.65-103.6%
$10Mvs $9M+3.2%
Q2 2025May 8, 2025
$1.17vs $2.01+41.8%
$9Mvs $7M+27.0%
Based on last 12 quarters of dataView full earnings history →

ASMB Peer Comparison

Assembly Biosciences, Inc. (ASMB) competitors in Vaccines and Infectious Disease — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ARWR logoARWRArrowhead Pharmaceuticals, Inc.Direct Competitor11.08B79.14-6486.89232.58%18.54%35.64%0.73
RCKT logoRCKTRocket Pharmaceuticals, Inc.Direct Competitor418.11M3.86-1.92-80.49%0.09
REPL logoREPLReplimune Group, Inc.Direct Competitor272.34M3.42-1.11-149.55%0.18
GILD logoGILDGilead Sciences, Inc.Product Competitor169.83B136.30358.686.04%28.9%37.62%1.39
REGN logoREGNRegeneron Pharmaceuticals, Inc.Product Competitor74.89B720.7817.380.99%29.65%14.32%0.09
ALNY logoALNYAlnylam Pharmaceuticals, Inc.Product Competitor40.43B303.00130.0465.19%13.46%98.29%1.62
VRTX logoVRTXVertex Pharmaceuticals IncorporatedProduct Competitor108.78B427.6527.919.57%35.4%23.93%0.21
INCY logoINCYIncyte CorporationProduct Competitor19.95B99.8515.5821.22%26.71%29.31%0.01

Compare ASMB vs Peers

Assembly Biosciences, Inc. (ASMB) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ARWR

Most directly comparable listed peer for ASMB.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare ASMB against a more recognizable public peer.

Peer Set

Compare Top 5

vs ARWR, RCKT, REPL, GILD

ASMB Income Statement

Assembly Biosciences, Inc. (ASMB) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue9.02M14.8M15.96M79.11M6.25M07.16M28.52M72.3M
Revenue Growth %-64.15%7.83%395.55%-92.09%-100%-298.16%153.52%
Cost of Goods Sold44.23M72.74M85.32M101.34M069.08M48.9M0129K
COGS % of Revenue490.37%491.36%534.51%128.1%--682.67%-0.18%
Gross Profit
-35.21M▲ 0%
-57.94M▼ 64.6%
-69.36M▼ 19.7%
-22.23M▲ 67.9%
6.25M▲ 128.1%
-69.08M▼ 1204.6%
-41.74M▲ 39.6%
28.52M▲ 168.3%
72.17M▲ 153.1%
Gross Margin %-390.37%-391.36%-434.51%-28.1%100%--582.67%100%99.82%
Gross Profit Growth %-43770.17%-64.56%-19.72%67.95%128.13%-1204.57%39.58%168.33%153.06%
Operating Expenses61.25M107.54M33.35M42.54M138.94M25.03M22.91M73.94M84.42M
OpEx % of Revenue679.09%726.42%208.93%53.78%2221.65%-319.82%259.26%116.76%
Selling, General & Admin17.02M34.8M34.86M36.86M28.78M23.93M22.91M18.01M19.61M
SG&A % of Revenue188.72%235.06%218.37%46.6%460.19%-319.82%63.14%27.12%
Research & Development44.23M72.74M85.76M106.82M68.52M69.98M48.9M55.93M64.81M
R&D % of Revenue490.37%491.36%537.22%135.04%1095.68%-682.67%196.12%89.64%
Other Operating Expenses00-87.26M-101.14M41.64M-68.88M-48.9M00
Operating Income
-52.23M▲ 0%
-92.73M▼ 77.6%
-102.71M▼ 10.8%
-64.78M▲ 36.9%
-132.69M▼ 104.8%
-94.11M▲ 29.1%
-64.65M▲ 31.3%
-45.42M▲ 29.7%
-12.12M▲ 73.3%
Operating Margin %-579.09%-626.42%-643.44%-81.89%-2121.65%--902.5%-159.26%-16.76%
Operating Income Growth %-15.35%-77.56%-10.76%36.94%-104.84%29.07%31.31%29.74%73.32%
EBITDA-52.01M-92.09M-102.22M-64.08M-132.22M-93.62M-64.2M-45.29M-11.99M
EBITDA Margin %-576.66%-622.08%-640.35%-81.01%-2114.2%--896.22%-158.8%-16.58%
EBITDA Growth %-15.07%-77.07%-11%37.31%-106.32%29.2%31.43%29.45%73.53%
D&A (Non-Cash Add-back)219.22K643K494K691K466K498K450K129K129K
EBIT-52.23M-92.73M-104.22M-59.09M-91.05M-93.01M-64.65M-45.42M-12.12M
Net Interest Income983K3.08M4.3M2.62M302K1.02M3.45M5.57M6M
Interest Income983.21K3.08M4.3M2.62M302K1.02M3.45M5.57M6M
Interest Expense000000000
Other Income/Expense368.2K3.08M5.85M2.62M302K1.02M3.45M5.57M6M
Pretax Income
-51.86M▲ 0%
-89.65M▼ 72.9%
-96.86M▼ 8.0%
-62.15M▲ 35.8%
-132.39M▼ 113.0%
-93.09M▲ 29.7%
-61.2M▲ 34.3%
-39.85M▲ 34.9%
-6.12M▲ 84.6%
Pretax Margin %-575.01%-605.59%-606.78%-78.57%-2116.82%--854.32%-139.72%-8.47%
Income Tax-9.05M1.1M774K0-2.53M033K330K0
Effective Tax Rate %17.45%-1.23%-0.8%0%1.91%0%-0.05%-0.83%0%
Net Income
-42.81M▲ 0%
-90.75M▼ 112.0%
-97.63M▼ 7.6%
-62.15M▲ 36.3%
-129.85M▼ 108.9%
-93.09M▲ 28.3%
-61.23M▲ 34.2%
-40.18M▲ 34.4%
-6.12M▲ 84.8%
Net Margin %-474.66%-613.02%-611.63%-78.57%-2076.35%--854.78%-140.87%-8.47%
Net Income Growth %3.28%-111.99%-7.58%36.34%-108.93%28.31%34.23%34.38%84.76%
Net Income (Continuing)-42.81M-90.75M-97.63M-62.15M-129.85M-93.09M-61.23M-40.18M-6.12M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
-24.10▲ 0%
-39.80▼ 65.1%
-27.80▲ 30.2%
-15.00▲ 46.0%
-36.00▼ 140.0%
-22.82▲ 36.6%
-13.38▲ 41.4%
-6.69▲ 50.0%
-0.55▲ 91.8%
EPS Growth %6.23%-65.15%30.15%46.04%-140%36.61%41.37%50%91.78%
EPS (Basic)-24.10-39.80-27.80-15.00-36.00-22.82-13.38-6.69-0.55
Diluted Shares Outstanding1.78M2.28M3.51M3.97M3.61M4.03M4.58M6M11.21M
Basic Shares Outstanding1.78M2.28M3.51M3.97M3.61M4.03M4.58M6M11.21M
Dividend Payout Ratio---------

ASMB Balance Sheet

Assembly Biosciences, Inc. (ASMB) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets123.12M222.5M282.78M224.49M154.2M96.97M133.79M115.5M254.55M
Cash & Short-Term Investments119.95M218.08M274.04M216.41M146.63M91.61M130.25M112.08M248.11M
Cash Only82.03M41.47M46.73M59.44M45.63M52.42M19.84M38.34M58.45M
Short-Term Investments37.91M176.61M227.31M156.97M101M39.19M110.41M73.73M189.66M
Accounts Receivable2.27M2.43M3.37M1.23M336K944K43K400K974K
Days Sales Outstanding92.0359.9177.155.6819.61-2.195.124.92
Inventory000000-3.2M00
Days Inventory Outstanding---------
Other Current Assets01.99M5.36M00300K3.5M3.02M5.47M
Total Non-Current Assets46.18M45.54M65.11M58.76M36.86M4.83M3.04M3.67M3.04M
Property, Plant & Equipment860.03K557K13.8M10.73M7.18M3.94M2.72M3.35M2.73M
Fixed Asset Turnover10.49x26.58x1.16x7.37x0.87x-2.63x8.51x26.49x
Goodwill12.64M12.64M12.64M12.64M00000
Intangible Assets29M29M29M29M00000
Long-Term Investments3.35M00027.97M0000
Other Non-Current Assets339.56K3.35M1.68M6.39M1.7M889K312K312K312K
Total Assets
169.3M▲ 0%
268.05M▲ 58.3%
347.89M▲ 29.8%
283.25M▼ 18.6%
191.06M▼ 32.5%
101.79M▼ 46.7%
136.82M▲ 34.4%
119.17M▼ 12.9%
257.59M▲ 116.2%
Asset Turnover0.05x0.06x0.05x0.28x0.03x-0.05x0.24x0.28x
Asset Growth %72.55%58.32%29.79%-18.58%-32.55%-46.72%34.41%-12.9%116.16%
Total Current Liabilities13.49M18.47M24.44M24.43M16.07M16.3M39.23M47.8M48.78M
Accounts Payable2.12M3.69M1.73M4.6M2.66M2.49M461K585K1.17M
Days Payables Outstanding17.5318.537.416.56-13.173.44-3.31K
Short-Term Debt003.19M00000569K
Deferred Revenue (Current)5.23M5.1M6.41M00030.91M37.62M36.9M
Other Current Liabilities6.85M4.67M7.8M7.02M6.43M599K1.15M9.13M10.14M
Current Ratio9.13x12.05x11.57x9.19x9.59x5.95x3.41x2.42x5.22x
Quick Ratio9.13x12.05x11.57x9.19x9.59x5.95x3.49x2.42x5.22x
Cash Conversion Cycle---------
Total Non-Current Liabilities42.69M38.92M50.23M18.24M6.06M2.83M56.5M38.01M2.06M
Long-Term Debt000000000
Capital Lease Obligations009.08M6.72M3.33M101K1.12M2.63M2.06M
Deferred Tax Liabilities2.14M3.25M10.51M2.53M00000
Other Non-Current Liabilities0108K0002.73M035.38M0
Total Liabilities56.18M57.39M74.67M42.68M22.13M19.13M95.73M85.81M50.84M
Total Debt0012.27M10.13M6.48M3.46M2.34M3.09M2.63M
Net Debt-82.03M-41.47M-34.46M-49.31M-39.15M-48.95M-17.5M-35.26M-55.82M
Debt / Equity--0.04x0.04x0.04x0.04x0.06x0.09x0.01x
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage---------
Total Equity
113.12M▲ 0%
210.65M▲ 86.2%
273.22M▲ 29.7%
240.58M▼ 11.9%
168.93M▼ 29.8%
82.66M▼ 51.1%
41.1M▼ 50.3%
33.36M▼ 18.8%
206.75M▲ 519.8%
Equity Growth %41.62%86.22%29.7%-11.95%-29.78%-51.07%-50.28%-18.83%519.78%
Book Value per Share63.7392.3977.8860.6346.8420.498.985.5618.44
Total Shareholders' Equity113.12M210.65M273.22M240.58M168.93M82.66M41.1M33.36M206.75M
Common Stock20.14K25K32K34K48K4K5K7K16K
Retained Earnings-251.04M-341.79M-439.42M-501.57M-631.43M-724.52M-785.75M-825.92M-832.05M
Treasury Stock000000000
Accumulated OCI-392.39K-347K-201K-270K-419K-803K-81K-211K-41K
Minority Interest000000000

ASMB Cash Flow Statement

Assembly Biosciences, Inc. (ASMB) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations1.86M-64.96M-84.07M-62.96M-93.4M-84.46M22.74M-51.12M-41.09M
Operating CF Margin %20.62%-438.79%-526.64%-79.59%-1493.38%-317.51%-179.23%-56.83%
Operating CF Growth %105.33%-3592.21%-29.42%25.11%-48.35%9.56%126.93%-324.76%19.61%
Net Income-42.81M-90.75M-97.63M-62.15M-129.85M-93.09M-61.23M-40.18M-6.12M
Depreciation & Amortization219.22K643K494K691K466K498K450K129K129K
Stock-Based Compensation8.6M28.48M20.56M21.85M5.24M6.59M5.12M3.12M4.68M
Deferred Taxes-9.05M1.1M-774K0-2.53M0000
Other Non-Cash Items615.13K-229K2.82M6.96M44.69M3.66M2.06M-2.24M-1.5M
Working Capital Changes44.28M-4.21M-9.53M-30.31M-11.4M-2.12M76.34M-11.95M-38.28M
Change in Receivables-2.27M-156K-944K2.14M894K-608K901K43K-974K
Change in Inventory1.1M-601K-3.01M000000
Change in Payables-244.19K1.57M-1.96M2.87M-1.94M-166K-2.03M124K586K
Cash from Investing-15.64M-135.4M-50.32M68.07M26.52M90.64M-69.14M40.17M-113.47M
Capital Expenditures-864.56K-340K-1.55M-470K-3.1M-102K-255K-28K-66K
CapEx % of Revenue9.59%2.3%9.74%0.59%49.5%-3.56%0.1%0.09%
Acquisitions-33.18B-48.88M-1.74M01.5M1.5M000
Investments---------
Other Investing33.18B48.88M1.74M-1.75M857K024K02.35M
Cash from Financing67.24M159.79M139.65M7.6M53.06M614K13.82M29.45M174.67M
Debt Issued (Net)000000000
Equity Issued (Net)67.24M155.43M134.66M5.45M52.81M325K13.69M29.29M174.67M
Dividends Paid000000000
Share Repurchases000000000
Other Financing04.37M4.99M2.15M258K289K129K155K0
Net Change in Cash
53.46M▲ 0%
-40.56M▼ 175.9%
5.26M▲ 113.0%
12.71M▲ 141.6%
-13.82M▼ 208.7%
6.79M▲ 149.1%
-32.58M▼ 579.7%
18.5M▲ 156.8%
20.11M▲ 8.7%
Free Cash Flow
995.52K▲ 0%
-65.3M▼ 6659.2%
-85.62M▼ 31.1%
-65.18M▲ 23.9%
-96.49M▼ 48.0%
-84.56M▲ 12.4%
22.49M▲ 126.6%
-51.15M▼ 327.4%
-41.16M▲ 19.5%
FCF Margin %11.04%-441.08%-536.37%-82.39%-1542.88%-313.95%-179.33%-56.93%
FCF Growth %102.84%-6659.2%-31.12%23.88%-48.05%12.36%126.59%-327.43%19.52%
FCF per Share0.56-28.64-24.41-16.43-26.75-20.964.91-8.52-3.67
FCF Conversion (FCF/Net Income)-0.04x0.72x0.86x1.01x0.72x0.91x-0.37x1.27x6.71x
Interest Paid000000000
Taxes Paid0000000421K0

ASMB Key Ratios

Assembly Biosciences, Inc. (ASMB) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-44.57%-44.36%-56.06%-40.36%-24.19%-63.42%-74%-98.95%-107.92%-5.1%
Return on Invested Capital (ROIC)-47.52%-95.09%-69.46%-37.77%-22.6%-62%-86.35%-169.2%-313.93%-12.2%
Gross Margin--390.37%-391.36%-434.51%-28.1%100%--582.67%100%99.82%
Net Margin--474.66%-613.02%-611.63%-78.57%-2076.35%--854.78%-140.87%-8.47%
Debt / Equity---0.04x0.04x0.04x0.04x0.06x0.09x0.01x
FCF Conversion0.79x-0.04x0.72x0.86x1.01x0.72x0.91x-0.37x1.27x6.71x
Revenue Growth--64.15%7.83%395.55%-92.09%-100%-298.16%153.52%

ASMB SEC Filings & Documents

Assembly Biosciences, Inc. (ASMB) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 30, 2026·SEC

Material company update

Mar 19, 2026·SEC

Material company update

Dec 8, 2025·SEC

10-K Annual Reports

3
FY 2026

Mar 19, 2026·SEC

FY 2025

Mar 20, 2025·SEC

FY 2024

Mar 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 6, 2025·SEC

FY 2025

May 8, 2025·SEC

ASMB Frequently Asked Questions

Assembly Biosciences, Inc. (ASMB) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Assembly Biosciences, Inc. (ASMB) reported $72.3M in revenue for fiscal year 2025.

Assembly Biosciences, Inc. (ASMB) grew revenue by 153.5% over the past year. This is strong growth.

Assembly Biosciences, Inc. (ASMB) reported a net loss of $6.1M for fiscal year 2025.

Dividend & Returns

Assembly Biosciences, Inc. (ASMB) has a return on equity (ROE) of -5.1%. Negative ROE indicates the company is unprofitable.

Assembly Biosciences, Inc. (ASMB) had negative free cash flow of $41.2M in fiscal year 2025, likely due to heavy capital investments.

Explore More ASMB

Assembly Biosciences, Inc. (ASMB) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

→

Price History

Long-term charts & historical price data

→

Revenue History

Sales growth patterns & revenue breakdown

→

Financial Ratios

30 years of market, efficiency and balance-sheet ratios

→

Valuation

DCF intrinsic value, peer multiples & estimates

→
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