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CLLS logoCellectis S.A.(CLLS)Earnings, Financials & Key Ratios

CLLS•NASDAQ
$3.95
$287M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
AboutCellectis S.A., a clinical stage biotechnological company, develops immuno-oncology products based on gene-edited T-cells that express chimeric antigen receptors to target and eradicate cancer cells. It operates through two segments, Therapeutics and Plants. The company is developing UCART19, an allogeneic T-cell product candidate for the treatment of CD19-expressing hematologic malignancies, such as acute lymphoblastic leukemia; ALLO-501 and ALLO-501A to treat relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma; ALLO-316 for the treatment of Renal Cell Carcinoma; UCART123 for the treatment of acute myeloid leukemia; and UCART22 to treat B-cell acute lymphoblastic leukemia. It is also developing UCARTCS1 and ALLO-715 for the treatment of multiple myeloma. The company has strategic alliances with Allogene Therapeutics, Inc.; Les Laboratoires Servier; The University of Texas M.D. Anderson Cancer Center; and Iovance Biotherapeutics, as well as a strategic research and development collaboration with Cytovia Therapeutics, Inc. Cellectis S.A. was founded in 1999 and is headquartered in Paris, France.Show more
  • Revenue$42M+5397.5%
  • EBITDA-$40M+49.6%
  • Net Income-$37M+63.6%
  • EPS (Diluted)-0.41+76.8%
  • Gross Margin77.88%+108.8%
  • EBITDA Margin-95.67%+99.1%
  • Operating Margin-143.48%+98.9%
  • Net Margin-88.57%+99.3%
  • ROE-34.08%+64.5%
  • ROIC-79.56%+21.0%
  • Debt/Equity0.70-30.5%
  • Interest Coverage-7.99+56.4%
Technical→

CLLS Key Insights

Cellectis S.A. (CLLS) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong Piotroski F-Score: 7/9
  • ✓FCF machine: 47.0% free cash flow margin
  • ✓Strong 5Y sales CAGR of 22.3%

✗Weaknesses

  • ✗Shares diluted 58.9% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

CLLS Price & Volume

Cellectis S.A. (CLLS) stock price & volume — 10-year historical chart

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CLLS Growth Metrics

Cellectis S.A. (CLLS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years4.67%
5 Years22.27%
3 Years11%
TTM158.91%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM58.67%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM66.37%

Return on Capital

10 Years-28.26%
5 Years-30.65%
3 Years-38.46%
Last Year-30.05%

CLLS Recent Earnings

Cellectis S.A. (CLLS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 5/12 qtrs (42%)
Q2 2026Latest
Mar 19, 2026
EPS
$0.26
Est $0.20
-27.9%
Revenue
$12M
Est $13M
-8.9%
Q4 2025
Nov 7, 2025
EPS
$0.01
Est $0.10
+110.0%
Revenue
$35M
Est $10M
+242.4%
Q3 2025
Aug 4, 2025
EPS
$0.24
Est $0.10
-140.0%
Revenue
$17M
Est $8M
+106.0%
Q2 2025
May 12, 2025
EPS
$0.18
Est $0.19
+5.3%
Revenue
$11M
Est $13M
-16.2%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 19, 2026
$0.26vs $0.20-27.9%
$12Mvs $13M-8.9%
Q4 2025Nov 7, 2025
$0.01vs $0.10+110.0%
$35Mvs $10M+242.4%
Q3 2025Aug 4, 2025
$0.24vs $0.10-140.0%
$17Mvs $8M+106.0%
Q2 2025May 12, 2025
$0.18vs $0.19+5.3%
$11Mvs $13M-16.2%
Based on last 12 quarters of dataView full earnings history →

CLLS Peer Comparison

Cellectis S.A. (CLLS) competitors in Cell and Gene Therapy Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
CRSP logoCRSPCRISPR Therapeutics AGDirect Competitor5.31B55.08-8.51-89.97%-138.57%-30.88%0.21
BEAM logoBEAMBeam Therapeutics Inc.Direct Competitor3.32B32.33-39.92120.01%-57.24%-7.31%0.24
EDIT logoEDITEditas Medicine, Inc.Direct Competitor310.73M3.18-1.76-100%-5.23%0.66
NTLA logoNTLAIntellia Therapeutics, Inc.Direct Competitor1.61B13.85-3.64-100%-61.47%0.14
FATE logoFATEFate Therapeutics, Inc.Product Competitor264.17M2.29-1.99-51.24%-20.51%-65.79%0.38
ALLO logoALLOAllogene Therapeutics, Inc.Product Competitor529.95M2.31-2.66-100%-57.07%0.26
SANA logoSANASana Biotechnology, Inc.Product Competitor954.64M3.64-3.14-120.02%0.38
CABA logoCABACabaletta Bio, Inc.Product Competitor381.44M3.73-2.27-121.73%0.24

Compare CLLS vs Peers

Cellectis S.A. (CLLS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CRSP

Most directly comparable listed peer for CLLS.

Scale Benchmark

vs TMO

Larger-name benchmark to compare CLLS against a more recognizable public peer.

Peer Set

Compare Top 5

vs CRSP, BEAM, EDIT, NTLA

CLLS Income Statement

Cellectis S.A. (CLLS) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue42.58M25.19M12.73M15.19M51.06M30.35M19.17M755K41.51M75.27M
Revenue Growth %-22.63%-40.85%-49.46%19.32%236.12%-40.56%-36.83%-96.06%5397.48%158.91%
Cost of Goods Sold1.69M2.62M2.74M11.39M1.95M1.84M8.48M7.42M9.18M9.31M
COGS % of Revenue3.96%10.4%21.51%75%3.82%6.08%44.25%982.65%22.12%-
Gross Profit
40.9M▲ 0%
22.57M▼ 44.8%
9.99M▼ 55.7%
3.8M▼ 62.0%
49.11M▲ 1192.9%
28.5M▼ 42.0%
10.69M▼ 62.5%
-6.66M▼ 162.4%
32.32M▲ 585.1%
65.96M▲ 0%
Gross Margin %96.04%89.6%78.49%25%96.18%93.92%55.75%-882.65%77.88%87.63%
Gross Profit Growth %-21.86%-44.82%-55.72%-61.99%1192.94%-41.96%-62.5%-162.36%585.05%-
Operating Expenses104.86M115.22M115.08M127.35M91.42M131.98M100.35M90.64M91.88M92.36M
OpEx % of Revenue246.23%457.43%903.96%838.38%179.05%434.93%523.46%12005.03%221.36%-
Selling, General & Admin41.26M44.75M47.25M43.02M22.51M22.88M8.89M8.12M8.42M8.04M
SG&A % of Revenue96.89%177.66%371.13%283.19%44.1%75.4%46.4%1075.36%20.29%-
Research & Development74.56M79.23M76.57M92.04M77.05M117.84M97.5M87.65M90.54M89.95M
R&D % of Revenue175.1%314.54%601.42%605.94%150.91%388.32%508.59%11608.74%218.13%-
Other Operating Expenses-19.38M-17.9M-25.42M-7.71M-8.14M-8.74M-6.04M-5.13M-7.08M-3.92M
Operating Income
-63.96M▲ 0%
-92.65M▼ 44.9%
-105.09M▼ 13.4%
-123.55M▼ 17.6%
-42.31M▲ 65.8%
-103.48M▼ 144.6%
-89.67M▲ 13.4%
-97.3M▼ 8.5%
-59.55M▲ 38.8%
-26.41M▲ 0%
Operating Margin %-150.2%-367.83%-825.47%-813.38%-82.87%-341%-467.72%-12887.68%-143.48%-35.08%
Operating Income Growth %-109.51%-44.85%-13.43%-17.57%65.75%-144.57%13.35%-8.52%38.79%-
EBITDA-61.75M-89.28M-102.71M-116.68M-34.48M-89.33M-71.23M-78.78M-39.71M-5.62M
EBITDA Margin %-145.01%-354.45%-806.8%-768.12%-67.53%-294.36%-371.56%-10434.3%-95.67%-7.46%
EBITDA Growth %-115.75%-44.58%-15.05%-13.59%70.45%-159.09%20.26%-10.6%49.6%90.52%
D&A (Non-Cash Add-back)2.21M3.37M2.38M6.88M7.83M14.16M18.43M18.52M19.85M20.79M
EBIT-67.25M-103.68M-88.29M-112.61M-51.17M-92.58M-94.81M-111.16M-29.31M-26.86M
Net Interest Income-583K1.41M6.06M4.02M-1.69M-3.65M-2.67M-1.69M3.83M3.18M
Interest Income44.17K1.97M6.79M6.98M1.96M719K1.12M3.61M11.28M10.99M
Interest Expense6.31K560K723K2.96M3.65M4.37M3.79M5.31M7.45M7.81M
Other Income/Expense47K-11.03M16.76M8.34M-11.27M6.73M-8.94M-19.16M22.79M-8.43M
Pretax Income
-63.92M▲ 0%
-103.68M▼ 62.2%
-88.33M▲ 14.8%
-115.21M▼ 30.4%
-53.58M▲ 53.5%
-96.75M▼ 80.6%
-98.6M▼ 1.9%
-116.46M▼ 18.1%
-36.76M▲ 68.4%
-34.84M▲ 0%
Pretax Margin %-150.09%-411.63%-693.84%-758.47%-104.94%-318.83%-514.32%-15425.7%-88.57%-46.28%
Income Tax-1.54M-13.2M000-3K87K371K0514K
Effective Tax Rate %2.42%12.73%0%0%0%0%-0.09%-0.32%0%-1.48%
Net Income
-63.92M▲ 0%
-99.37M▼ 55.5%
-78.69M▲ 20.8%
-102.09M▼ 29.7%
-81.07M▲ 20.6%
-114.2M▼ 40.9%
-106.14M▲ 7.1%
-101.06M▲ 4.8%
-36.76M▲ 63.6%
-35.35M▲ 0%
Net Margin %-150.1%-394.51%-618.12%-672.09%-158.79%-376.32%-553.64%-13385.3%-88.57%-46.97%
Net Income Growth %-184.58%-55.46%20.81%-29.73%20.59%-40.86%7.06%4.79%63.62%58.67%
Net Income (Continuing)-67.25M-103.68M-88.33M-115.21M-53.58M-96.75M-98.69M-116.83M-36.76M-35.35M
Discontinued Operations0000-43.9M-28.36M-15.35M8.39M00
Minority Interest1.87M19.11M40.97M40.35M25.05M15.18M7.97M000
EPS (Diluted)
-1.78▲ 0%
-2.78▼ 56.2%
-1.93▲ 30.6%
-2.14▼ 10.9%
-1.71▲ 20.1%
-1.93▼ 12.9%
-2.33▼ 20.7%
-1.77▲ 24.0%
-0.41▲ 76.8%
-0.35▲ 0%
EPS Growth %-173.85%-56.18%30.58%-10.88%20.09%-12.87%-20.73%24.03%76.84%66.37%
EPS (Basic)-1.81-2.78-1.93-2.14-1.71-1.93-2.33-1.77-0.41-
Diluted Shares Outstanding35.81M35.69M40.77M42.44M42.5M44.82M45.55M57.01M90.57M100.33M
Basic Shares Outstanding35.29M35.69M40.77M42.44M42.5M44.82M45.55M57.01M90.57M100.33M
Dividend Payout Ratio----------

CLLS Balance Sheet

Cellectis S.A. (CLLS) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets311.79M323.22M487.64M391.52M315.36M225.43M143.81M233.01M287.07M221.19M
Cash & Short-Term Investments290.5M296.98M451.89M360.91M268.24M186.13M97.7M203.81M260.31M190.22M
Cash Only290.5M296.98M451.89M360.91M241.15M185.64M89.79M136.71M143.25M52.24M
Short-Term Investments000027.09M499K7.91M67.11M117.06M137.98M
Accounts Receivable3.63M4.57M22.07M15.29M19.19M31.07M17.57M23.13M23.04M26.41M
Days Sales Outstanding31.0966.15632.66367.48137.22373.74334.5911.18K202.59126.5
Inventory117.79K250K275K2.9M1.61M00000
Days Inventory Outstanding25.4734.8336.6592.82300.46-----
Other Current Assets363K2.99M2.42M594K12.21M50K22.31M345K298K4.55M
Total Non-Current Assets18.89M9.66M13.2M75.95M154.11M156.65M117.41M101.27M96.48M121.85M
Property, Plant & Equipment16.86M7.23M10.04M69.32M145.52M148.27M107.9M92.74M75.86M66.71M
Fixed Asset Turnover2.53x3.49x1.27x0.22x0.35x0.20x0.18x0.01x0.55x1.05x
Goodwill0000000000
Intangible Assets1.34M1.43M1.27M1.11M1.58M1.85M718K672K1.11M845K
Long-Term Investments689.92K1M1.89M5.52M7.01M6.52M8.79M7.85M7.52M13.32M
Other Non-Current Assets0102K-1K5.52M-1K3K0-1K11.6M130.41M
Total Assets
330.68M▲ 0%
332.88M▲ 0.7%
500.84M▲ 50.5%
467.47M▼ 6.7%
469.47M▲ 0.4%
382.08M▼ 18.6%
261.22M▼ 31.6%
334.27M▲ 28.0%
383.54M▲ 14.7%
343.05M▲ 0%
Asset Turnover0.13x0.08x0.03x0.03x0.11x0.08x0.07x0.00x0.11x0.21x
Asset Growth %-11.32%0.67%50.46%-6.66%0.43%-18.62%-31.63%27.97%14.74%-8.95%
Total Current Liabilities56.04M43.53M46.87M62.6M52.02M49.35M62.99M155.14M166.27M148.58M
Accounts Payable9.72M9.46M15.88M29.26M24.61M23.76M21.46M19.07M18.66M16.09M
Days Payables Outstanding2.1K1.32K2.12K937.624.6K4.7K923.08938.16741.93680.95
Short-Term Debt1.69M00002.25M4.97M5.16M4.84M5.45M
Deferred Revenue (Current)38.84M26.06M20.75M20.03M452K301K59K110.33M112.16M338.84M
Other Current Liabilities1.46M2.02M2.86M4.95M7.21M2.16M16.16M2.72M13.37M118.7M
Current Ratio5.56x7.42x10.40x6.25x6.06x4.57x2.28x1.50x1.73x1.73x
Quick Ratio5.56x7.42x10.40x6.21x6.03x4.57x2.28x1.50x1.73x1.73x
Cash Conversion Cycle-2.05K-1.22K-1.45K-477.32-4.17K-----554.45
Total Non-Current Liabilities588.95K3.44M3.7M49.4M108.61M96.25M72.28M94.43M95.25M93.99M
Long-Term Debt000024.22M18.77M13.57M28.44M43.99M49.74M
Capital Lease Obligations30K13K1.02M46.54M75.76M71.53M49.36M42.95M34.24M128.9M
Deferred Tax Liabilities0000000158K00
Other Non-Current Liabilities560K3.43M2.68M2.85M8.63M5.96M9.35M22.88M17.02M32.4M
Total Liabilities56.63M46.98M50.57M112M160.63M145.6M135.28M249.57M252.51M242.57M
Total Debt1.76M34K1.35M47.61M106.68M100.87M75.77M85.06M91.46M92.78M
Net Debt-288.74M-296.95M-450.54M-313.3M-134.47M-84.77M-14.02M-51.65M-51.79M40.53M
Debt / Equity0.01x0.00x0.00x0.13x0.35x0.43x0.60x1.00x0.70x0.70x
Debt / EBITDA----------16.52x
Net Debt / EBITDA----------7.22x
Interest Coverage-10136.33x-165.45x-145.35x-41.75x-11.58x-23.69x-23.68x-18.33x-7.99x-3.44x
Total Equity
274.05M▲ 0%
285.9M▲ 4.3%
450.27M▲ 57.5%
355.47M▼ 21.1%
308.85M▼ 13.1%
236.47M▼ 23.4%
125.94M▼ 46.7%
84.69M▼ 32.8%
131.03M▲ 54.7%
100.48M▲ 0%
Equity Growth %-4.92%4.33%57.49%-21.05%-13.12%-23.43%-46.74%-32.75%54.71%26%
Book Value per Share7.658.0111.048.387.275.282.761.491.451.00
Total Shareholders' Equity272.18M266.79M409.3M315.12M283.8M221.29M117.97M84.69M131.03M100.48M
Common Stock1.86M2.37M2.77M2.77M2.79M2.94M2.96M4.37M5.89M5.9M
Retained Earnings-229.77M-351.3M-405.32M-508.48M-587.03M-698.33M-439.5M-405.77M-329.61M-307.86M
Treasury Stock-416K-297K00000000
Accumulated OCI2.63M1.98M-16.67M-22.64M-4.09M-18.02M-28.61M-36.69M-39.54M-32.73M
Minority Interest1.87M19.11M40.97M40.35M25.05M15.18M7.97M000

CLLS Cash Flow Statement

Cellectis S.A. (CLLS) cash flow — operating, investing & free cash flow history

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations-31.09M-52.33M-68.14M-69.14M-80.26M-104.56M-87.44M-24.75M22.1M22.1M
Operating CF Margin %-73%-207.75%-535.21%-455.18%-157.2%-344.57%-456.13%-3277.62%53.25%-
Operating CF Growth %-978.69%-68.32%-30.21%-1.47%-16.08%-30.28%16.37%71.7%189.32%-120.43%
Net Income-63.92M-103.68M-88.33M-115.21M-53.58M-96.75M-98.69M-116.83M-36.7M-35.35M
Depreciation & Amortization2.1M3.37M2.38M6.88M7.83M14.16M18.43M18.52M19.84M20.79M
Stock-Based Compensation55.71M50.42M37.22M26.88M10.03M11.49M6.04M5.23M03.14M
Deferred Taxes1.32M4.32M6.46M00087K371K0-25K
Other Non-Cash Items-1.4M11.04M-16.76M661K-27.22M-21.16M-7.6M71.95M-14.61M-1.09M
Working Capital Changes-24.9M-17.79M-9.1M11.65M-17.32M-12.3M-5.72M-3.99M53.57M-16.55M
Change in Receivables-947.58K-549K-3.7M4.68M-3.23M-12.44M-8.99M2.25M-6.72M2.04M
Change in Inventory47.33K-109K-37K-2.63M100K215K0000
Change in Payables-4.17M-335K9.37M9.63M5.69M177K3.25M-6.3M2.05M-3.31M
Cash from Investing-50.5M1.78M35.62M-35.87M-54.34M7.28M-2.76M-15.51M-102.63M-68.6M
Capital Expenditures-13.34M-2.66M-4.89M-12.91M-44.08M-18.54M-2.43M-1.07M-3.84M-2.43M
CapEx % of Revenue31.32%10.54%38.38%85.01%86.33%61.11%12.68%142.12%9.24%-
Acquisitions-298.68K7.16M1.26M0000000
Investments----------
Other Investing321.82K7.16M1.26M369K-13.15M10.96M-456K-14.44M0-3.46M
Cash from Financing460.64K41.27M236.49M-3.86M27.32M47.52M1.15M82.86M89.8M-9.7M
Debt Issued (Net)-91K-41K-127K-3.39M19.43M-10.64M-6.6M24.56M18.17M-8.98M
Equity Issued (Net)576K1000K1000K01000K1000K-569K1000K1000K-1K
Dividends Paid0000000000
Share Repurchases-137K00-469K00-569K000
Other Financing007.77M-469K-1.32M13.53M8.32M-9.63M-11.04M-718K
Net Change in Cash
-76.5M▲ 0%
1.81M▲ 102.4%
195.12M▲ 10668.3%
-110.98M▼ 156.9%
-99.37M▲ 10.5%
-55.51M▲ 44.1%
-92.42M▼ 66.5%
43.49M▲ 147.1%
6.54M▼ 85.0%
-106.84M▲ 0%
Free Cash Flow
-44.42M▲ 0%
-54.98M▼ 23.8%
-73.02M▼ 32.8%
-82.1M▼ 12.4%
-124.68M▼ 51.9%
-123.12M▲ 1.3%
-89.89M▲ 27.0%
-25.82M▲ 71.3%
19.52M▲ 175.6%
-32.71M▲ 0%
FCF Margin %-104.32%-218.29%-573.58%-540.49%-244.21%-405.71%-468.86%-3419.74%47.04%-43.46%
FCF Growth %-6113.1%-23.77%-32.81%-12.43%-51.87%1.26%26.99%71.28%175.62%-154.18%
FCF per Share-1.24-1.54-1.79-1.93-2.93-2.75-1.97-0.450.220.22
FCF Conversion (FCF/Net Income)0.49x0.53x0.87x0.68x0.99x0.92x0.82x0.24x-0.60x0.93x
Interest Paid0000000000
Taxes Paid0000000000

CLLS Key Ratios

Cellectis S.A. (CLLS) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)-22.74%-35.49%-21.38%-25.34%-24.41%-41.88%-58.57%-95.96%-34.08%-31.79%
Return on Invested Capital (ROIC)----442.28%-29.31%-47.6%-51.02%-100.68%-79.56%-79.56%
Gross Margin96.04%89.6%78.49%25%96.18%93.92%55.75%-882.65%77.88%87.63%
Net Margin-150.1%-394.51%-618.12%-672.09%-158.79%-376.32%-553.64%-13385.3%-88.57%-46.97%
Debt / Equity0.01x0.00x0.00x0.13x0.35x0.43x0.60x1.00x0.70x0.70x
Interest Coverage-10136.33x-165.45x-145.35x-41.75x-11.58x-23.69x-23.68x-18.33x-7.99x-3.44x
FCF Conversion0.49x0.53x0.87x0.68x0.99x0.92x0.82x0.24x-0.60x0.93x
Revenue Growth-22.63%-40.85%-49.46%19.32%236.12%-40.56%-36.83%-96.06%5397.48%158.91%

CLLS Frequently Asked Questions

Cellectis S.A. (CLLS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Cellectis S.A. (CLLS) reported $75.3M in revenue for fiscal year 2024. This represents a 1735% increase from $4.1M in 2007.

Cellectis S.A. (CLLS) grew revenue by 5397.5% over the past year. This is strong growth.

Cellectis S.A. (CLLS) reported a net loss of $35.4M for fiscal year 2024.

Dividend & Returns

Cellectis S.A. (CLLS) has a return on equity (ROE) of -34.1%. Negative ROE indicates the company is unprofitable.

Cellectis S.A. (CLLS) had negative free cash flow of $32.7M in fiscal year 2024, likely due to heavy capital investments.

Explore More CLLS

Cellectis S.A. (CLLS) financial analysis — history, returns, DCA and operating performance tools

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