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CVKDCadrenal Therapeutics, Inc. Common Stock
$3.05$8M
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CVKD logoCadrenal Therapeutics, Inc. Common Stock(CVKD)Earnings, Financials & Key Ratios

CVKD•NASDAQ
$3.05
Price updated Jun 27, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutCadrenal Therapeutics, Inc. operates as a clinical development biopharmaceutical company. The company focuses on developing Tecarfarin, a novel therapy with orphan drug indication for the prevention of systemic thromboembolism of cardiac origin in patients with end-stage renal disease and atrial fibrillation. The company was incorporated in 2022 and is headquartered in Ponte Vedra, Florida.Show more
  • Revenue$0
  • EBITDA-$13M-22.8%
  • Net Income-$13M-24.3%
  • EPS (Diluted)-6.64+23.9%
  • ROE-260.11%-84.8%

CVKD Price & Volume

Cadrenal Therapeutics, Inc. Common Stock (CVKD) stock price & volume — 10-year historical chart

Loading chart...

Clinical Development Costs Threaten Capital Runway Sustainability

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Binary clinical trial dependency

Key Thesis Takeaways

  • Cadrenal Therapeutics remains a high-risk, pre-revenue biotechnology entity entirely dependent on the successful progression of its clinical pipeline.
  • The company faces significant financial headwinds, characterized by a rapid depletion of its cash reserves and a persistent reliance on external financing to fund ongoing operational losses.
  • Investors should monitor the firm's ability to secure additional capital, as the current $2.3 million cash position appears insufficient to sustain long-term Phase 3 clinical trial requirements.

Verdict Logic

the company's cash position has dwindled to $2.3 million as of 2026Q1, which may necessitate immediate and highly dilutive financing to maintain its going concern status.

CVKD Growth Metrics

Cadrenal Therapeutics, Inc. Common Stock (CVKD) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM7.36%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM39.2%

Return on Capital

10 Years-207.77%
5 Years-207.77%
3 Years-207.77%
Last Year-264.51%

CVKD Recent Earnings

Cadrenal Therapeutics, Inc. Common Stock (CVKD) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (36%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$1.04+31.1%
$1.51
Rev
—
—
Q2 2026
Mar 31, 2026
Metric
Actual
Est
EPS
$1.41-20.5%
$1.17
Rev
—
—
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$1.31+15.5%
$1.55
Rev
—
—
Q3 2025
Aug 11, 2025
Metric
Actual
Est
EPS
$1.87-16.9%
$1.60
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$1.04vs $1.51+31.1%
—
Q2 2026Mar 31, 2026
$1.41vs $1.17-20.5%
—
Q4 2025Nov 10, 2025
$1.31vs $1.55+15.5%
—
Q3 2025Aug 11, 2025
$1.87vs $1.60-16.9%
—
Based on last 12 quarters of dataView full earnings history →

Latest CVKD News

Recent stock market news and headlines for Cadrenal Therapeutics, Inc. Common Stock (CVKD)

GlobeNewsWire·5 days ago
Cadrenal Therapeutics Announces Selection of CAD-1005 Phase 2 Study for Late-Breaking Oral Presentation at ISTH 2026 Congress

Selection highlights the clinical value potential of Cadrenal's first-in-class 12-lipoxygenase inhibitor for Heparin-Induced Thrombocytopenia (HIT) First-ever randomized, blinded, placebo-controlled trial in HIT, a life-threatening blood-clotting disorder triggered by an immune reaction to heparin, the most widely used blood thinner in hospitals Phase-3 ready and addresses a peak $2 billion annual revenue potential in the HIT market PONTE VEDRA, Fla., June 24, 2026 (GLOBE NEWSWIRE) -- Cadrenal Therapeutics, Inc. (Nasdaq: CVKD), a biopharmaceutical company advancing late-stage novel therapies for life-threatening immune and thrombotic conditions, today announced that late-breaking clinical data on its first-in-class 12-lipoxygenase (12-LOX) inhibitor, CAD-1005 (formerly VLX-1005), have been accepted for a prestigious oral presentation at the 34th Congress of the International Society on Thrombosis and Haemostasis (ISTH).

GlobeNewsWire·Jun 18, 2026
Cadrenal Therapeutics to File for FDA Rare Pediatric Disease Designation for Tecarfarin in Kawasaki Disease

Company to present Phase 3-ready pipeline, 12-LOX platform, and pediatric rare-disease expansion to global pharmaceutical partners at the 2026 BIO International Convention in San Diego Kawasaki disease is the leading cause of acquired heart disease in children in developed nations. Patients are at risk of forming blood clots in coronary arteries and may require lifelong treatment If the designation is granted and tecarfarin is approved for this indication, Cadrenal would be eligible to receive a Priority Review Voucher—recent open-market valuations for these vouchers have reached into the ~$200 million range PONTE VEDRA, Fla.

Peers Comparison

Key metrics vs top competitors for Cadrenal Therapeutics, Inc. Common Stock (CVKD)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CVKD logoCVKDCadrenal Therapeutics, Inc. Common StockCurrent
$3.05$7.64M-0.46——-260.11%—
PTGX logoPTGXProtagonist Therapeutics, Inc.
$121.88$7.84B-59.45-89.41%-648.27%-17.76%—
TCRX logoTCRXTScan Therapeutics, Inc.
$0.97$125.86M-0.97266.65%-1360.61%-91.94%—
NKTR logoNKTRNektar Therapeutics
$63.65$1.24B-6.54-43.89%-284.18%-87%—
ARDX logoARDXArdelyx, Inc.
$5.55$1.36B-21.3522.09%-13.58%-38.11%—
BMRN logoBMRNBioMarin Pharmaceutical Inc.
$59.00$11.35B32.7812.87%8.29%4.41%—

Compare CVKD vs Peers

Cadrenal Therapeutics, Inc. Common Stock (CVKD) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PTGX

Most directly comparable listed peer for CVKD.

Scale Benchmark

vs JNJ

Larger-name benchmark to compare CVKD against a more recognizable public peer.

Peer Set

Compare Top 5

vs PTGX, TCRX, NKTR, ARDX

CVKD SEC Filings & Documents

Cadrenal Therapeutics, Inc. Common Stock (CVKD) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Apr 30, 2026·SEC

Material company update

Apr 1, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 31, 2026·SEC

FY 2025

Mar 13, 2025·SEC

FY 2024

Mar 11, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 11, 2025·SEC

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CVKD Frequently Asked Questions

Cadrenal Therapeutics, Inc. Common Stock (CVKD) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is CVKD profitable?

Cadrenal Therapeutics, Inc. Common Stock (CVKD) reported a net loss of $11.9M for fiscal year 2025.

Dividend & Returns
What is CVKD's return on equity?

Cadrenal Therapeutics, Inc. Common Stock (CVKD) has a return on equity (ROE) of -260.1%. Negative ROE indicates the company is unprofitable.

What is Cadrenal Therapeutics, Inc. Common Stock's free cash flow?

Cadrenal Therapeutics, Inc. Common Stock (CVKD) had negative free cash flow of $11.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CVKD back in 2022?

Total return calculator · dividends reinvested · 4+ years of data

See returns →