Exact Sciences is demonstrating significant top-line momentum with 23.1% year-over-year revenue growth in 2025Q4, yet the firm remains challenged by a persistent inability to achieve operating leverage as SG&A expenses continue to outpace gross profit.
Price trend, volume and key moving averages
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Revenue growth accelerated to 23.1% in 2025Q4, though the company continues to struggle with profitability as evidenced by a -9.4% operating margin.
Exact Sciences' collaboration with Walgreens integrates Cologuard into pharmacy workflows, increasing accessibility for average-risk customers.
The FDA-approved at-home colorectal cancer screening test is being promoted through nationwide initiatives, driving potential market penetration.
Pharmacist-led services for Cologuard requests aim to close care gaps, enhancing patient engagement and test utilization.
Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).
Check whether operating performance supports the current valuation.
Recent results and news deserve attention only when they alter the forward view.
| Quarter | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|
Q1 2026Latest Feb 13, 2026 | -$0.45-316.9% vs -$0.11 | $878M+2.0% vs $861M |
Q4 2025 Nov 3, 2025 | $0.24+492.0% vs -$0.06 | $851M+5.0% vs $811M |
Q3 2025 Aug 6, 2025 | $0.22+1200.0% vs -$0.02 | $811M+0.1% vs $810M |
Q2 2025 May 1, 2025 | -$0.54-45.9% vs -$0.37 | $707M+2.6% vs $689M |
Benchmark EXAS against direct peers instead of judging its metrics in isolation.
Key metrics vs top competitors for Exact Sciences Corporation (EXAS)
| Company | Price | Market Cap | P/E Ratio | Rev Growth (1Y) | Net Margin | ROE | Div Yield |
|---|---|---|---|---|---|---|---|
| $104.91 | $20.02B | -95.37 | 17.69% | -6.4% | -8.66% | — | |
| $150.87 | $20.01B | -45.44 | 32.88% | -38.33% | — | — | |
| $310.67 | $44.49B | -204.39 | 35.9% | -7.11% | -11.73% | — | |
| $213.13 | $32.25B | 39.11 | -0.78% | 19.72% | 31.45% | — | |
| $366.57 | $30.06B | 35.04 | 7.25% | 6.88% | 11.52% | 0.78% | |
| $255.63 | $28.21B | 29.21 | 11.78% | 9.53% | 14.66% | 1.22% |
Exact Sciences Corporation (EXAS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
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Exact Sciences Corporation (EXAS) SEC filings — annual & quarterly reports (10-K, 10-Q)
Mar 23, 2026·SEC
Mar 20, 2026·SEC
Feb 20, 2026·SEC
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Exact Sciences Corporation (EXAS) stock FAQ — growth, dividends, profitability & financials explained
Exact Sciences Corporation (EXAS) reported $3.25B in revenue in fiscal year 2025, which is also its trailing twelve months.
Exact Sciences Corporation (EXAS) grew revenue by 17.7% in fiscal year 2025, compared with the prior fiscal year.
No. Exact Sciences Corporation (EXAS) reported a net loss of $207.9M over the trailing twelve months.
Exact Sciences Corporation (EXAS) had a return on equity (ROE) of -8.7% in fiscal year 2025. A negative ROE means the company lost money over the period.
Exact Sciences Corporation (EXAS) generated $356.8M in free cash flow over the trailing twelve months.
