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PSNLPersonalis, Inc.
$16.28$1.7B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
Live BreakoutsStock ScreenerOwnership
PSNL logo

Personalis, Inc.

PSNL
NASDAQ · Diagnostics & Research
$16.28
At close - Oct 2, 4:00 PM EDT - USD
Market Cap$1.74B
P/E-17.9x
52W High$18.89
Volume1.11M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Clinical Volume Surge Masks Persistent Cash Burn

Personalis is navigating a pivotal inflection, with Q2 2026 clinical volume surging 199% YoY and revenue up 33% sequentially to $22.4M, yet the company remains deeply unprofitable, posting a -150.2% operating margin and a -$31.7M net loss. The balance sheet, b...

GrowthMixed
ProfitabilityWeak
ValuationReview
TechnicalsHealthy
Explore valuation models
MARKET ACTION

PSNL price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

9/12 Beats

EPS beat 9 of last 12 quarters

02

Valuation risk

-139% Peers

P/E is 139% below peer median

03

Market leadership

RS 94 · Leader

High momentum (Outperforming 94% of market)

04

Healthy Uptrend

Uptrend

Price > 50DMA > 200DMA

Next CatalystEstimated earnings · Nov 4

Market performance

Price History →

Trailing total returns as of 10/3/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
PSNL+107.39%
S&P 500 (^GSPC)+12.66%
1-Year Return
PSNL+140.47%
S&P 500 (^GSPC)+15.01%
3-Year Return
PSNL+1192.06%
S&P 500 (^GSPC)+82.48%
5-Year Return
PSNL-6.33%
S&P 500 (^GSPC)+98.84%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E
-17.9x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-17.9x
N/A
N/A
EV/EBITDA
N/A
N/A
N/A
Price/FCF
N/A
N/A
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$1.20-92.6%
Base (Fair)$11.77-27.7%
Bull$1.40-91.4%
$1.20 Bear$11.77 Base$1.40 Bull
Current Market Price: $16.28
Trades at a 38.3% premium to Base DCF ($11.77)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue
$70M-17.7% YoY
Net income
-$81M+0.0% YoY
Free cash flow
-$79M-69.9% YoY
Operating margin
-126.4%-45.8 pts YoY
ROIC (TTM)-39.7%
Avg ROIC 5Y-
ROE (TTM)-35%
Piotroski Score4 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate9/12 (75%)
Revenue Beat Rate9/12 (75%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 4, 2026
-$0.30-13.9%
vs -$0.26
$22M+34.0%
vs $17M
Q2 2026
May 7, 2026
-$0.29-26.1%
vs -$0.23
$15M+6.8%
vs $14M
Q1 2026
Feb 26, 2026
-$0.26+16.1%
vs -$0.31
$17M+1.7%
vs $17M
Q4 2025
Nov 4, 2025
-$0.24+14.3%
vs -$0.28
$14M-14.9%
vs $17M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Defense World·Sep 24, 2026
Aaron Tachibana Sells 2,931 Shares of Personalis (NASDAQ:PSNL) Stock

Personalis, Inc. (NASDAQ: PSNL - Get Free Report) CFO Aaron Tachibana sold 2,931 shares of the stock in a transaction dated Friday, September 18th. The shares were sold at an average price of $16.22, for a total transaction of $47,540.82. Following the completion of the sale, the chief financial officer owned 195,902 shares of the company's

Defense World·Sep 24, 2026
Stephen Michael Moore Sells 2,068 Shares of Personalis (NASDAQ:PSNL) Stock

Personalis, Inc. (NASDAQ: PSNL - Get Free Report) SVP Stephen Moore sold 2,068 shares of the business's stock in a transaction dated Friday, September 18th. The stock was sold at an average price of $16.22, for a total transaction of $33,542.96. Following the sale, the senior vice president owned 90,257 shares in the company, valued at

Defense World·Sep 24, 2026
Richard Chen Sells 3,998 Shares of Personalis (NASDAQ:PSNL) Stock

Personalis, Inc. (NASDAQ: PSNL - Get Free Report) CMO Richard Chen sold 3,998 shares of the company's stock in a transaction that occurred on Friday, September 18th. The shares were sold at an average price of $16.22, for a total value of $64,847.56. Following the completion of the transaction, the chief marketing officer directly owned 169,882

Defense World·Sep 23, 2026
Personalis (NASDAQ:PSNL) CEO Christopher Hall Sells 7,459 Shares

Personalis, Inc. (NASDAQ: PSNL - Get Free Report) CEO Christopher Hall sold 7,459 shares of the firm's stock in a transaction that occurred on Friday, September 18th. The stock was sold at an average price of $16.22, for a total value of $120,984.98. Following the completion of the sale, the chief executive officer owned 228,527 shares

Filtered for Personalis, Inc.More Headlines
04

Compare before deciding

Benchmark PSNL against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Personalis, Inc. (PSNL)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
PSNL logoPSNLPersonalis, Inc.Current
$16.28$1.74B-17.89-17.69%-116.69%-35.02%—
NTRA logoNTRANatera, Inc.
$410.35$58.77B-269.9735.9%-7.11%-11.73%—
EXAS logoEXASExact Sciences Corporation
$104.91$20.02B-95.3717.69%-6.4%-8.66%—
GH logoGHGuardant Health, Inc.
$177.80$23.58B-53.5532.88%-38.33%——
TWST logoTWSTTwist Bioscience Corporation
$188.67$11.75B-145.1320.32%-31.66%-29.89%—
ILMN logoILMNIllumina, Inc.
$273.04$41.31B50.10-0.78%18.36%31.08%—

Compare PSNL vs Peers

Personalis, Inc. (PSNL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NTRA

Most directly comparable listed peer for PSNL.

Scale Benchmark

vs TMO

Larger-name benchmark to compare PSNL against a more recognizable public peer.

Peer Set

Compare Top 5

vs NTRA, EXAS, GH, TWST

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

PSNL SEC Filings & Documents

Personalis, Inc. (PSNL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 4, 2026·SEC

Material company update

Jul 20, 2026·SEC

Material company update

Jul 20, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 4, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 4, 2025·SEC

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PSNL Frequently Asked Questions

Personalis, Inc. (PSNL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Personalis, Inc.'s revenue?

Personalis, Inc. (PSNL) reported $69.7M in revenue for fiscal year 2025. This represents a 642% increase from $9.4M in 2017.

How fast is Personalis, Inc. growing?

Personalis, Inc. (PSNL) saw revenue decline by 17.7% over the past year.

Is PSNL profitable?

Personalis, Inc. (PSNL) reported a net loss of $107.2M for fiscal year 2025.

Dividend & Returns
What is PSNL's return on equity?

Personalis, Inc. (PSNL) has a return on equity (ROE) of -35.0%. Negative ROE indicates the company is unprofitable.

What is Personalis, Inc.'s free cash flow?

Personalis, Inc. (PSNL) had negative free cash flow of $101.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in PSNL back in 2017?

Total return calculator · dividends reinvested · 9+ years of data

See returns →