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HEPAHepion Pharmaceuticals, Inc.
$0.06$698622
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HEPA logoHepion Pharmaceuticals, Inc.(HEPA)Earnings, Financials & Key Ratios

HEPA•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryMetabolic and Obesity Therapies
AboutHepion Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development of drug therapy treatment for chronic liver diseases in the United States. It is involved in developing Rencofilstat, a cyclophilin inhibitor that has completed Phase 2a clinical trials to target multiple pathologic pathways involved in the progression of liver disease; and is in clinical-phase development for the treatment of non-alcoholic steatohepatitis (NASH), as well as in nonclinical studies to reduce liver fibrosis and hepatocellular carcinoma tumor burden in experimental models of NASH, and has demonstrated antiviral activities towards hepatitis B, C, and D viruses through several mechanisms. The company was formerly known as ContraVir Pharmaceuticals, Inc. and changed its name to Hepion Pharmaceuticals, Inc. in July 2019. Hepion Pharmaceuticals, Inc. was incorporated in 2013 and is headquartered in Edison, New Jersey.Show more
  • Revenue$0
  • EBITDA-$8M+57.3%
  • Net Income-$8M+37.3%
  • EPS (Diluted)-0.88+99.2%
  • ROE-2058.63%-322.7%

HEPA Key Insights

Hepion Pharmaceuticals, Inc. (HEPA) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Strong 5Y profit CAGR of 16.5%
  • ✓Momentum leader: RS Rating 86 (top 14%)
  • ✓Trading at only 0.2x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Shares diluted 100.0% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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HEPA Price & Volume

Hepion Pharmaceuticals, Inc. (HEPA) stock price & volume — 10-year historical chart

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HEPA Growth Metrics

Hepion Pharmaceuticals, Inc. (HEPA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM81.86%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM99.69%

Return on Capital

10 Years-195.89%
5 Years-253.69%
3 Years-387.75%
Last Year-671.34%

HEPA Peer Comparison

Hepion Pharmaceuticals, Inc. (HEPA) competitors in Metabolic and Obesity Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
MDGL logoMDGLMadrigal Pharmaceuticals, Inc.Direct Competitor11.66B505.75-39.36432.05%-27.32%-50.15%0.59
AKRO logoAKROAkero Therapeutics, Inc.Direct Competitor4.5B54.65-14.57-30.58%0.05
HALO logoHALOHalozyme Therapeutics, Inc.Direct Competitor8.13B68.5526.7837.55%23.13%126.27%43.89
TERN logoTERNTerns Pharmaceuticals, Inc.Direct Competitor4.77B52.95-51.41-20.02%0.00
ELVN logoELVNEnliven Therapeutics, Inc.Direct Competitor2.75B45.10-24.64-21.04%0.00
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.19B60.98-6.27-43.89%-284.18%-87%1.66
GNFT logoGNFTGenfit S.A.Product Competitor447.53M8.95256.88134.56%-14.12%-22.98%0.90
HIMS logoHIMSHims & Hers Health, Inc.Product Competitor7.79B35.4769.5559%-0.56%-2.48%2.34

Compare HEPA vs Peers

Hepion Pharmaceuticals, Inc. (HEPA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs MDGL

Most directly comparable listed peer for HEPA.

Scale Benchmark

vs ALNY

Larger-name benchmark to compare HEPA against a more recognizable public peer.

Peer Set

Compare Top 5

vs MDGL, AKRO, HALO, TERN

HEPA Income Statement

Hepion Pharmaceuticals, Inc. (HEPA) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0000000000
Revenue Growth %
----------
Cost of Goods Sold
21.94K18.79K26.74K0000000
COGS % of Revenue
----------
Gross Profit
-21.94K▲ 0%
-18.79K▲ 14.4%
-26.74K▼ 42.3%
0▲ 100.0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
Gross Margin %
----------
Gross Profit Growth %
-14.36%-42.32%100%------
Operating Expenses
21.02M14.59M7.77M20.15M30.4M45.49M48.45M19.35M4.16M3.68M
OpEx % of Revenue
----------
Selling, General & Admin
6.69M7M4.59M8.15M10.01M10.35M9.62M7.5M3.32M2.79M
SG&A % of Revenue
----------
Research & Development
14.33M7.59M3.18M12M20.4M33.27M35.64M11.85M445.51K493.28K
R&D % of Revenue
----------
Other Operating Expenses
0-108.94K0001.87M3.19M0402.75K402.75K
Operating Income
-21.04M▲ 0%
-14.59M▲ 30.6%
-7.77M▲ 46.8%
-20.15M▼ 159.3%
-30.4M▼ 50.9%
-45.49M▼ 49.6%
-48.45M▼ 6.5%
-19.35M▲ 60.1%
-4.16M▲ 78.5%
-3.68M▲ 0%
Operating Margin %
----------
Operating Income Growth %
-0.09%30.65%46.76%-159.28%-50.91%-49.62%-6.51%60.07%78.48%-
EBITDA
-21.02M-14.58M-7.74M-20.11M-30.32M-45.41M-48.38M-19.32M-8.25M-3.68M
EBITDA Margin %
----------
EBITDA Growth %
-0.12%30.66%46.87%-159.73%-50.75%-49.79%-6.54%60.08%57.27%76.72%
D&A (Non-Cash Add-back)
21.94K18.79K26.74K34.52K86.07K77.46K67.13K30.76K00
EBIT
-18.92M-14.59M-7.77M-20.15M-32.71M-45.07M-49.33M-14.91M-8.25M-2.97M
Net Interest Income
00-555K-31.23K-8.86K-10.16K-9.46K-1.25M-24.41K-22.82K
Interest Income
0000000000
Interest Expense
0339.16K555K31.23K8.86K10.16K9.46K1.25M24.41K22.82K
Other Income/Expense
2.13M4.61M-175.94K-177.28K-2.32M404.83K-887.11K3.18M-4.11M698.85K
Pretax Income
-18.92M▲ 0%
-9.99M▲ 47.2%
-7.95M▲ 20.4%
-20.32M▼ 155.8%
-32.72M▼ 61.0%
-45.08M▼ 37.8%
-49.34M▼ 9.4%
-16.16M▲ 67.2%
-8.28M▲ 48.8%
-2.98M▲ 0%
Pretax Margin %
----------
Income Tax
-3.9M-536K-908.68K30.58K0-2.88M-409.02K-2.97M00
Effective Tax Rate %
20.59%5.37%11.44%-0.15%0%6.4%0.83%18.37%0%0%
Net Income
-15.02M▲ 0%
-9.45M▲ 37.1%
-7.04M▲ 25.5%
-20.35M▼ 189.2%
-32.72M▼ 60.8%
-42.2M▼ 29.0%
-48.93M▼ 15.9%
-13.19M▲ 73.0%
-8.28M▲ 37.3%
-2.98M▲ 0%
Net Margin %
----------
Net Income Growth %
-0.88%37.1%25.53%-189.23%-60.77%-28.96%-15.94%73.04%37.25%81.86%
Net Income (Continuing)
-15.02M-9.45M-7.04M-20.35M-32.72M-42.2M-48.93M-13.19M-8.28M-2.98M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-106400.00▲ 0%
-97353.00▲ 8.5%
-6108.07▲ 93.7%
-2103.70▲ 65.6%
-465.52▲ 77.9%
-594.75▼ 27.8%
-616.07▼ 3.6%
-107.35▲ 82.6%
-0.88▲ 99.2%
-0.26▲ 0%
EPS Growth %
-3053.59%8.5%93.73%65.56%77.87%-27.76%-3.58%82.58%99.18%99.69%
EPS (Basic)
-106400.00-97353.00-6108.07-2103.70-465.52-594.75-616.07-107.35-0.88-
Diluted Shares Outstanding
1381842.04K9.68K70.29K76.23K79.42K122.89K9.41M11.62M
Basic Shares Outstanding
1381842.04K9.68K70.29K76.23K79.42K122.89K9.41M11.62M
Dividend Payout Ratio
----------

HEPA Balance Sheet

Hepion Pharmaceuticals, Inc. (HEPA) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
6.06M2.97M14.39M42.63M97.45M56.5M17.49M1.61M3.07M2.71M
Cash & Short-Term Investments
5.95M2.83M13.92M40.73M91.35M51.19M14.79M406.41K1.83M2.6M
Cash Only
5.95M2.83M13.92M40.73M91.35M51.19M14.79M406.41K1.83M2.6M
Short-Term Investments
0000000000
Accounts Receivable
0000000000
Days Sales Outstanding
----------
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
0000000000
Total Non-Current Assets
5.19M5.22M6.22M6.01M6.1M3.75M606.56K000
Property, Plant & Equipment
56.59K32.43K855.08K664.93K456.46K3.32M242.37K000
Fixed Asset Turnover
----------
Goodwill
1.87M1.87M1.87M1.87M1.87M00000
Intangible Assets
03.19M3.19M3.19M3.19M3.19M0000
Long-Term Investments
000-731.3K000000
Other Non-Current Assets
3.26M127.79K306.88K285.1K582.85K-2.76M364.19K000
Total Assets
11.25M▲ 0%
8.19M▼ 27.2%
20.61M▲ 151.7%
48.65M▲ 136.0%
103.55M▲ 112.9%
60.24M▼ 41.8%
18.09M▼ 70.0%
1.61M▼ 91.1%
3.07M▲ 90.2%
2.71M▲ 0%
Asset Turnover
---------0.00x
Asset Growth %
-38.79%-27.23%151.69%136.01%112.87%-41.82%-69.97%-91.08%90.24%8.7%
Total Current Liabilities
2.6M2.85M1.61M4.66M8.21M7.89M5.29M3.14M299.38K735.57K
Accounts Payable
1.56M748.43K491.56K3.72M2.45M2.67M2.35M220.2K167.81K138.44K
Days Payables Outstanding
25.9K14.54K6.71K-------
Short-Term Debt
01.44M000002.9M54.07K0
Deferred Revenue (Current)
0000000000
Other Current Liabilities
00002.99M2.27M386K00597.13K
Current Ratio
2.33x1.04x8.94x9.15x11.88x7.16x3.31x0.51x10.25x3.68x
Quick Ratio
2.33x1.04x8.94x9.15x11.88x7.16x3.31x0.51x10.25x3.68x
Cash Conversion Cycle
----------
Total Non-Current Liabilities
4.95M3.36M3.39M3.46M2.35M2.5M5.52M333.19K103.02K113.17K
Long-Term Debt
000176.59K000000
Capital Lease Obligations
00540.75K295.75K50.34K093.1K000
Deferred Tax Liabilities
896.7K360.7K409.02K409.02K0409.02K0000
Other Non-Current Liabilities
4.05M3M2.44M2.58M2.3M2.09M5.43M333.19K103.02K113.17K
Total Liabilities
7.55M6.21M4.99M8.12M10.56M10.39M10.81M3.48M402.4K848.75K
Total Debt
01.44M807.45K752.17K316.99K53.61K209.02K2.9M54.07K0
Net Debt
-5.95M-1.39M-13.12M-39.97M-91.03M-51.14M-14.58M2.49M-1.77M-2.6M
Debt / Equity
-0.73x0.05x0.02x0.00x0.00x0.03x-0.02x0.00x
Debt / EBITDA
----------0.00x
Net Debt / EBITDA
---------0.71x
Interest Coverage
--43.03x-14.00x-645.11x-3692.66x-4434.65x-5211.37x-11.96x-338.17x-130.18x
Total Equity
3.7M▲ 0%
1.98M▼ 46.7%
15.62M▲ 690.7%
40.52M▲ 159.5%
93M▲ 129.5%
49.86M▼ 46.4%
7.28M▼ 85.4%
-1.86M▼ 125.6%
2.67M▲ 243.2%
1.86M▲ 0%
Equity Growth %
-59.12%-46.67%690.7%159.47%129.5%-46.39%-85.4%-125.59%243.16%1114.86%
Book Value per Share
26783.6510741.047644.004187.291323.00654.0391.68-15.160.280.16
Total Shareholders' Equity
3.7M1.98M15.62M40.52M93M49.86M7.28M-1.86M2.67M1.86M
Common Stock
7.83K253753.2K7.62K381482141.16K1.16K
Retained Earnings
-67.01M-76.46M-83.75M-104.11M-133.5M-175.7M-224.63M-237.82M-246.1M-246.91M
Treasury Stock
6.85K000000000
Accumulated OCI
00000-90.17K-78.78K8.35K8.35K8.35K
Minority Interest
0000000000

HEPA Cash Flow Statement

Hepion Pharmaceuticals, Inc. (HEPA) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-8.21M-15.65M-7.57M-16.17M-31.22M-34.96M-40.89M-18.22M-3.27M-1.58M
Operating CF Margin %
----------
Operating CF Growth %
57.18%-90.59%51.65%-113.68%-93.16%-11.97%-16.96%55.45%82.04%392.62%
Net Income
-15.02M-9.45M-7.04M-20.35M-32.72M-42.2M-48.93M-13.19M-8.28M-2.98M
Depreciation & Amortization
21.94K18.79K26.74K34.52K86.07K77.46K67.13K30.76K00
Stock-Based Compensation
1.57K234.51K66.18K2.38M4.67M2.55M1.34M791.64K20.78K0
Deferred Taxes
-372.92K-536K48.32K000-409.02K000
Other Non-Cash Items
7.34M-4.94M157.28K146.05K2.31M1.46M4.07M-3.16M4.49M-1.2M
Working Capital Changes
-19.21K-970.48K-826.23K1.63M-5.57M3.15M2.97M-2.68M493.05K1.79M
Change in Receivables
0000000000
Change in Inventory
0000000000
Change in Payables
-111.21K-897.7K-317.05K0-1.07M0000352.47K
Cash from Investing
-2900-51.47K-85.79K-130.41K-14.07K-14.3K-600K-132.12K-132.12K
Capital Expenditures
-20-51.47K-87.98K-130.41K-16.34K-14.3K000
CapEx % of Revenue
----------
Acquisitions
090000000000
Investments
----------
Other Investing
0102.19K02.27K0-600K0-132.12K
Cash from Financing
1.18M12.52M18.71M43.05M81.98M-5.14M4.49M4.35M4.83M-276.18K
Debt Issued (Net)
01.33M-1.12M176.59K-176.59K000-3.37M-368.82K
Equity Issued (Net)
1.18M12.05M17.74M42.87M82.15M-3.14M02.5M9M0
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
11.9M-857.4K2.09M12K0-2M4.49M1.85M-802.6K92.65K
Net Change in Cash
-1.45M▲ 0%
-3.12M▼ 115.3%
11.09M▲ 455.3%
26.8M▲ 141.7%
50.62M▲ 88.9%
-40.16M▼ 179.3%
-36.4M▲ 9.4%
-14.38M▲ 60.5%
1.42M▲ 109.9%
-1.98M▲ 0%
Free Cash Flow
-8.21M▲ 0%
-15.65M▼ 90.6%
-7.62M▲ 51.3%
-16.25M▼ 113.4%
-31.35M▼ 92.9%
-34.98M▼ 11.6%
-40.9M▼ 16.9%
-18.22M▲ 55.5%
-3.27M▲ 82.0%
-1.58M▲ 0%
FCF Margin %
----------
FCF Growth %
57.21%-90.59%51.32%-113.39%-92.92%-11.55%-16.94%55.46%82.04%89.98%
FCF per Share
-59374.94-85088.71-3728.11-1679.57-446.07-458.85-515.05-148.23-0.35-0.14
FCF Conversion (FCF/Net Income)
0.55x1.66x1.07x0.79x0.95x0.83x0.84x1.38x0.40x0.53x
Interest Paid
000009410000
Taxes Paid
0000000000

HEPA Key Ratios

Hepion Pharmaceuticals, Inc. (HEPA) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-235.44%-332.83%-80.01%-72.52%-49.02%-59.08%-171.26%-487.03%-2058.63%-102.45%
Return on Invested Capital (ROIC)
--1878.68%-377.95%-991.8%-1817.84%-9983.03%--2302.24%-409.86%-423.24%
Debt / Equity
-0.73x0.05x0.02x0.00x0.00x0.03x-0.02x0.00x
Interest Coverage
--43.03x-14.00x-645.11x-3692.66x-4434.65x-5211.37x-11.96x-338.17x-130.18x
FCF Conversion
0.55x1.66x1.07x0.79x0.95x0.83x0.84x1.38x0.40x0.53x
Related:HEPA Dividend History·HEPA Revenue History·HEPA Price History·HEPA P/E History·HEPA Financial Ratios·HEPA Institutional Holders

HEPA SEC Filings & Documents

Hepion Pharmaceuticals, Inc. (HEPA) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 22, 2026·SEC

Material company update

Apr 14, 2026·SEC

Material company update

Mar 18, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 12, 2026·SEC

FY 2025

Apr 8, 2025·SEC

FY 2024

Apr 16, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 14, 2025·SEC

HEPA Frequently Asked Questions

Hepion Pharmaceuticals, Inc. (HEPA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Hepion Pharmaceuticals, Inc. (HEPA) grew revenue by 0.0% over the past year. Growth has been modest.

Hepion Pharmaceuticals, Inc. (HEPA) reported a net loss of $3.0M for fiscal year 2025.

Dividend & Returns

Hepion Pharmaceuticals, Inc. (HEPA) has a return on equity (ROE) of -2058.6%. Negative ROE indicates the company is unprofitable.

Hepion Pharmaceuticals, Inc. (HEPA) had negative free cash flow of $1.6M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in HEPA back in 2012?

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