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Werewolf Therapeutics, Inc. (HOWL) 10-Year Financial Performance & Capital Metrics

HOWL • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsImmuno-Oncology
AboutWerewolf Therapeutics, Inc., a biopharmaceutical company, develops therapeutics engineered to stimulate the body's immune system for the treatment of cancer. The company, through its proprietary PREDATOR platform, designs conditionally activated molecules that stimulate adaptive and innate immunity for addressing the limitations of conventional proinflammatory immune therapies. Its lead product candidates are WTX-124, a conditionally activated Interleukin-2 INDUKINE molecule for the treatment of advanced solid tumors; and WTX-330, a conditionally activated Interleukin-12 INDUKINE molecule for the treatment of relapsed or refractory advanced or metastatic solid tumors or lymphoma. The company is also developing WTX-613, a conditionally activated interferon alpha INDUKINE molecule for the treatment of solid tumors and hematologic malignancies. Werewolf Therapeutics, Inc. was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue $2M -90.5%
  • EBITDA -$72M -85.3%
  • Net Income -$71M -88.7%
  • EPS (Diluted) -1.63 -55.2%
  • Gross Margin 3.77% -95.9%
  • EBITDA Margin -3807.96% -1860.4%
  • Operating Margin -3904.19% -1822.4%
  • Net Margin -3740.85% -1896.5%
  • ROE -76.33% -138.7%
  • ROIC -388.21% -134.2%
  • Debt/Equity 0.51 +8.4%
  • Interest Coverage -15.81 -22.5%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Trading at only 0.3x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 5 (bottom 5%)
  • ✗Shares diluted 23.0% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-100%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-17.26%

EPS CAGR

10Y-
5Y-
3Y-
TTM-8%

ROCE

10Y Avg-41.6%
5Y Avg-39.8%
3Y Avg-39.93%
Latest-55.08%

Peer Comparison

Immuno-Oncology
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
IMTXImmatics N.V.1.33B9.9270.86188.6%-136.72%-27.81%0.03
CTMXCytomX Therapeutics, Inc.720.1M4.2511.1836.45%24.66%26.09%
IOVAIovance Biotherapeutics, Inc.881.27M2.22-1.73136.99%-158.78%-56.62%0.08
REPLReplimune Group, Inc.572.64M7.30-2.38-117.82%0.18
NKTRNektar Therapeutics719.28M35.36-4.079.22%-192.87%-141.9%1.69
IMNMImmunome, Inc.2.52B22.85-4.57-35.5%-23.01%-84.4%0.03
IBRXImmunityBio, Inc.3.89B3.95-6.3722.71%-422.28%
NRIXNurix Therapeutics, Inc.1.91B18.86-6.55-29.15%-292.5%-65.76%0.05

Profit & Loss

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+00016.4M19.94M1.89M
Revenue Growth %----0.22%-0.91%
Cost of Goods Sold+463K777K02.51M1.76M1.81M
COGS % of Revenue---0.15%0.09%0.96%
Gross Profit+-463K-777K013.89M18.18M71K
Gross Margin %---0.85%0.91%0.04%
Gross Profit Growth %--0.68%1%-0.31%-1%
Operating Expenses+9.94M21.63M50.09M69.95M58.68M73.67M
OpEx % of Revenue---4.26%2.94%39.08%
Selling, General & Admin3.6M5.76M14.82M21.5M18.67M19.05M
SG&A % of Revenue---1.31%0.94%10.1%
Research & Development6.34M16.64M35.27M53.76M41.78M56.43M
R&D % of Revenue---3.28%2.09%29.94%
Other Operating Expenses0-777K0-5.32M-1.76M-1.81M
Operating Income+-9.94M-22.4M-50.09M-56.06M-40.5M-73.59M
Operating Margin %----3.42%-2.03%-39.04%
Operating Income Growth %--1.25%-1.24%-0.12%0.28%-0.82%
EBITDA+-9.47M-21.63M-49.87M-53.55M-38.74M-71.78M
EBITDA Margin %----3.26%-1.94%-38.08%
EBITDA Growth %--1.28%-1.31%-0.07%0.28%-0.85%
D&A (Non-Cash Add-back)463K777K216K2.51M1.76M1.81M
EBIT-9.88M-15.04M-50.09M-53.81M-34.23M-65.86M
Net Interest Income+0101K104K1.91M4.28M2.02M
Interest Income372K101K104K1.91M7.42M6.67M
Interest Expense372K0003.14M4.66M
Other Income/Expense-312K7.36M104K2.25M3.13M3.08M
Pretax Income+-10.25M-15.04M-49.98M-53.81M-37.37M-70.52M
Pretax Margin %----3.28%-1.87%-37.41%
Income Tax+000000
Effective Tax Rate %1.07%0.99%1%1%1%1%
Net Income+-10.99M-14.94M-49.98M-53.81M-37.37M-70.52M
Net Margin %----3.28%-1.87%-37.41%
Net Income Growth %--0.36%-2.35%-0.08%0.31%-0.89%
Net Income (Continuing)-10.25M-15.04M-49.98M-53.81M-37.37M-70.52M
Discontinued Operations000000
Minority Interest000000
EPS (Diluted)+-0.38-0.98-10.94-1.86-1.05-1.63
EPS Growth %--1.58%-10.16%0.83%0.44%-0.55%
EPS (Basic)-0.38-0.98-10.94-1.86-1.05-1.63
Diluted Shares Outstanding28.66M28.66M18.45M28.86M35.65M43.86M
Basic Shares Outstanding28.66M28.66M18.45M28.86M35.65M43.33M
Dividend Payout Ratio------

Balance Sheet

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+18.06M92.91M161.07M140.2M138.37M113.07M
Cash & Short-Term Investments17.9M92.57M157.53M129.31M134.34M111M
Cash Only17.9M92.57M157.53M129.31M134.34M111M
Short-Term Investments000000
Accounts Receivable0006.93M1.35M0
Days Sales Outstanding---154.1824.71-
Inventory000000
Days Inventory Outstanding------
Other Current Assets75K0100K3.96M2.68M2.07M
Total Non-Current Assets+3.62M3.48M18.18M20.05M36.46M13.86M
Property, Plant & Equipment3.41M3.12M16.32M17.45M14.85M12.32M
Fixed Asset Turnover---0.94x1.34x0.15x
Goodwill000000
Intangible Assets000000
Long-Term Investments0001.21M21.02M1.22M
Other Non-Current Assets208K362K1.86M1.38M594K320K
Total Assets+21.68M96.4M179.25M160.25M174.83M126.93M
Asset Turnover---0.10x0.11x0.01x
Asset Growth %-3.45%0.86%-0.11%0.09%-0.27%
Total Current Liabilities+2.04M5.28M11.87M23.99M19.38M15.18M
Accounts Payable633K1.02M2.04M1.22M1.34M3.04M
Days Payables Outstanding499.02479.62-177.56276.44610.68
Short-Term Debt00006.67M0
Deferred Revenue (Current)0001000K907K0
Other Current Liabilities094K163K11.02M3.63M10.59M
Current Ratio8.84x17.58x13.56x5.84x7.14x7.45x
Quick Ratio8.84x17.58x13.56x5.84x7.14x7.45x
Cash Conversion Cycle------
Total Non-Current Liabilities+9.87M1.9M14.59M13.92M44.08M38.36M
Long-Term Debt000032.66M26.09M
Capital Lease Obligations2.54M1.86M14.59M12.6M10.99M9.44M
Deferred Tax Liabilities000000
Other Non-Current Liabilities7.32M31K01.32M433K2.83M
Total Liabilities11.91M7.18M26.46M37.91M63.46M53.54M
Total Debt+3.14M2.54M15.66M14.68M51.92M37.09M
Net Debt-14.76M-90.03M-141.87M-114.63M-82.42M-73.91M
Debt / Equity0.32x0.03x0.10x0.12x0.47x0.51x
Debt / EBITDA------
Net Debt / EBITDA------
Interest Coverage-26.71x----12.90x-15.81x
Total Equity+9.77M89.22M152.79M122.34M111.37M73.39M
Equity Growth %-8.13%0.71%-0.2%-0.09%-0.34%
Book Value per Share0.343.118.284.243.121.67
Total Shareholders' Equity9.77M89.22M152.79M122.34M111.37M73.39M
Common Stock2K2K2K3K4K5K
Retained Earnings-24.41M-51.87M-252.9M-306.7M-344.07M-414.59M
Treasury Stock000000
Accumulated OCI000000
Minority Interest000000

Cash Flow

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-9.54M-18.62M-42.88M-40.6M-32.61M-56.19M
Operating CF Margin %----2.48%-1.64%-29.81%
Operating CF Growth %--0.95%-1.3%0.05%0.2%-0.72%
Net Income-10.25M-15.04M-49.98M-53.81M-37.37M-70.52M
Depreciation & Amortization25K150K216K1.1M1.76M1.81M
Stock-Based Compensation559K632K4.09M7.4M8.01M8.83M
Deferred Taxes-117K00000
Other Non-Cash Items950K-6.29M519K2.17M878K1.16M
Working Capital Changes-711K1.92M2.28M2.54M-5.89M2.53M
Change in Receivables000-6.93M5.58M1.35M
Change in Inventory0006.93M00
Change in Payables116K01.01M-883K-4.33M3.46M
Cash from Investing+-266K-560K-498K-3.61M-769K-254K
Capital Expenditures-266K-560K-498K-3.61M-769K-254K
CapEx % of Revenue---0.22%0.04%0.13%
Acquisitions------
Investments------
Other Investing000000
Cash from Financing+21.91M93.86M109.43M15.91M58.43M13.08M
Debt Issued (Net)------
Equity Issued (Net)------
Dividends Paid000000
Share Repurchases------
Other Financing-193K93.86M-2.17M166K100K-496K
Net Change in Cash------
Free Cash Flow+-9.81M-19.18M-43.37M-44.21M-33.38M-56.44M
FCF Margin %----2.7%-1.67%-29.94%
FCF Growth %--0.96%-1.26%-0.02%0.24%-0.69%
FCF per Share-0.34-0.67-2.35-1.53-0.94-1.29
FCF Conversion (FCF/Net Income)0.87x1.25x0.86x0.75x0.87x0.80x
Interest Paid000000
Taxes Paid000000

Key Ratios

Metric201920202021202220232024
Return on Equity (ROE)-112.5%-30.18%-41.31%-39.12%-31.98%-76.33%
Return on Invested Capital (ROIC)---743.35%-451.51%-165.72%-388.21%
Gross Margin---84.7%91.15%3.77%
Net Margin----328.09%-187.37%-3740.85%
Debt / Equity0.32x0.03x0.10x0.12x0.47x0.51x
Interest Coverage-26.71x----12.90x-15.81x
FCF Conversion0.87x1.25x0.86x0.75x0.87x0.80x
Revenue Growth----21.6%-90.55%

Revenue by Segment

2024
Reportable1.89M
Reportable Growth-

Frequently Asked Questions

Growth & Financials

Werewolf Therapeutics, Inc. (HOWL) reported $1.9M in revenue for fiscal year 2024.

Werewolf Therapeutics, Inc. (HOWL) saw revenue decline by 90.5% over the past year.

Werewolf Therapeutics, Inc. (HOWL) reported a net loss of $72.8M for fiscal year 2024.

Dividend & Returns

Werewolf Therapeutics, Inc. (HOWL) has a return on equity (ROE) of -76.3%. Negative ROE indicates the company is unprofitable.

Werewolf Therapeutics, Inc. (HOWL) had negative free cash flow of $63.6M in fiscal year 2024, likely due to heavy capital investments.

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