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IMCRImmunocore Holdings plc
$28.60$1.5B
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IMCR logoImmunocore Holdings plc(IMCR)Earnings, Financials & Key Ratios

IMCR•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutImmunocore Holdings plc, a commercial-stage biotechnology company, engages in the development of immunotherapies for the treatment of cancer, infectious, and autoimmune diseases. The company offers KIMMTRAK for the treatment of patients with unresectable or metastatic uveal melanoma. Its other programs for oncology comprise IMC-C103C that is in Phase I/II dose escalation trial in patients with solid tumor cancers, including non-small-cell lung (NSCLC), gastric, head and neck, ovarian, and synovial sarcoma cancers; IMC-F106C, which is in a Phase I/II dose escalation trial in patients with multiple solid tumor cancers comprising NSCLC, small-cell lung, endometrial, ovarian, cutaneous melanoma, and breast cancers. In addition, the company's programs for infectious diseases include IMC-I109V, which is in a Phase I/II clinical trial in patients with chronic hepatitis B virus; and IMC-M113V that is in pre-clinical development stage for patients with human immunosuppression virus. Further, it develops product candidates to provide precision targeted immunosuppression for the treatment of autoimmune diseases. Immunocore Holdings plc was founded in 1999 and is headquartered in Abingdon, the United Kingdom.Show more
  • Revenue$298M+20.0%
  • EBITDA-$31M+40.8%
  • Net Income-$26M+35.3%
  • EPS (Diluted)-0.53+48.0%
  • Gross Margin97.91%+0.2%
  • EBITDA Margin-10.52%+50.7%
  • Operating Margin-11.34%+50.0%
  • Net Margin-8.88%+46.0%
  • ROE-7.12%+43.0%

IMCR Key Insights

Immunocore Holdings plc (IMCR) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y profit CAGR of 18.6%
  • ✓Strong 5Y sales CAGR of 58.1%

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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IMCR Price & Volume

Immunocore Holdings plc (IMCR) stock price & volume — 10-year historical chart

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IMCR Growth Metrics

Immunocore Holdings plc (IMCR) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years33.2%
5 Years58.11%
3 Years27.3%
TTM15.64%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM12.98%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM11.2%

Return on Capital

10 Years-34.23%
5 Years-18.54%
3 Years-8.62%
Last Year-4.17%

IMCR Recent Earnings

Immunocore Holdings plc (IMCR) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)●Beat Revenue 5/12 qtrs (42%)
Q2 2026Latest
May 6, 2026
Metric
Actual
Est
EPS
$0.25+196.2%
$0.26
Rev
$145M-0.3%
$145M
Q1 2026
Feb 25, 2026
Metric
Actual
Est
EPS
$0.60-114.3%
$0.28
Rev
$140M-3.1%
$144M
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.02+105.2%
$0.30
Rev
$104M-27.1%
$142M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.20+4.8%
$0.21
Rev
$134M+0.1%
$134M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 6, 2026
$0.25vs $0.26+196.2%
$145Mvs $145M-0.3%
Q1 2026Feb 25, 2026
$0.60vs $0.28-114.3%
$140Mvs $144M-3.1%
Q4 2025Nov 6, 2025
$0.02vs $0.30+105.2%
$104Mvs $142M-27.1%
Q3 2025Aug 7, 2025
$0.20vs $0.21+4.8%
$134Mvs $134M+0.1%
Based on last 12 quarters of dataView full earnings history →

IMCR Peer Comparison

Immunocore Holdings plc (IMCR) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
KYMR logoKYMRKymera Therapeutics, Inc.Direct Competitor7.38B90.43-24.51-16.72%-6.12%-25.02%0.05
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.45B24.31-7.39-4.26%-156.36%-68.97%0.16
AGEN logoAGENAgenus Inc.Direct Competitor124.93M3.00-882.3510.37%52.16%
MGNX logoMGNXMacroGenics, Inc.Direct Competitor262.52M4.13-3.500.78%-44.79%-147.8%1.92
FATE logoFATEFate Therapeutics, Inc.Direct Competitor243.61M2.09-1.82-51.24%-20.57%-58.89%0.38
ADCT logoADCTADC Therapeutics S.A.Direct Competitor138.64M1.09-0.9714.85%-173.02%
GILD logoGILDGilead Sciences, Inc.Product Competitor153.66B123.7618.252.39%30.99%42.33%1.09
EXEL logoEXELExelixis, Inc.Product Competitor13.19B51.9118.676.98%35.08%40.21%0.08

Compare IMCR vs Peers

Immunocore Holdings plc (IMCR) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs KYMR

Most directly comparable listed peer for IMCR.

Scale Benchmark

vs MRK

Larger-name benchmark to compare IMCR against a more recognizable public peer.

Peer Set

Compare Top 5

vs KYMR, RCUS, AGEN, MGNX

IMCR Income Statement

Immunocore Holdings plc (IMCR) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
19.17M23.65M25.67M30.11M27.04M144.23M197.39M247.98M297.57M385.76M
Revenue Growth %
-5.19%23.42%8.52%17.32%-10.19%433.32%36.85%25.63%20%15.64%
Cost of Goods Sold
0099.99M74.81M05.29M820.63K5.54M6.21M4.61M
COGS % of Revenue
--389.54%248.42%-3.67%0.42%2.24%2.09%-
Gross Profit
19.17M▲ 0%
23.65M▲ 23.4%
-74.32M▼ 414.2%
-44.7M▲ 39.9%
27.04M▲ 160.5%
138.94M▲ 413.7%
196.57M▲ 41.5%
242.44M▲ 23.3%
291.36M▲ 20.2%
381.15M▲ 0%
Gross Margin %
100%100%-289.54%-148.42%100%96.33%99.58%97.76%97.91%98.81%
Gross Profit Growth %
-5.19%23.42%-414.2%39.86%160.51%413.74%41.47%23.34%20.18%-
Operating Expenses
109.94M117.73M44M41.5M156.46M181.71M243.77M298.77M325.09M410.51M
OpEx % of Revenue
573.67%497.72%171.41%137.8%578.53%125.99%123.5%120.48%109.25%-
Selling, General & Admin
29.22M34.16M44.18M45.74M82.15M0114.35M121.17M120.62M151.41M
SG&A % of Revenue
152.47%144.4%172.13%151.89%303.76%-57.93%48.86%40.54%-
Research & Development
81.13M83.58M99.99M74.81M74.31M84.31M129.42M177.44M204.47M259.11M
R&D % of Revenue
423.34%353.32%389.54%248.42%274.77%58.45%65.57%71.55%68.71%-
Other Operating Expenses
-411.37K0-100.18M-79.05M097.4M0000
Operating Income
-90.78M▲ 0%
-93.45M▼ 2.9%
-118.32M▼ 26.6%
-86.19M▲ 27.2%
-129.42M▼ 50.1%
-42.77M▲ 66.9%
-47.2M▼ 10.4%
-56.28M▼ 19.2%
-33.74M▲ 40.1%
-29.36M▲ 0%
Operating Margin %
-473.67%-395.09%-460.95%-286.22%-478.53%-29.66%-23.91%-22.7%-11.34%-7.61%
Operating Income Growth %
-127.66%-2.95%-26.61%27.15%-50.15%66.95%-10.36%-19.23%40.05%-
EBITDA
-85.53M-86.75M-111.56M-79.75M-123.79M-38.36M-43.97M-52.92M-31.31M-27.16M
EBITDA Margin %
-446.26%-366.74%-434.61%-264.82%-457.72%-26.6%-22.27%-21.34%-10.52%-7.04%
EBITDA Growth %
-133.86%-1.43%-28.6%28.52%-55.23%69.01%-14.61%-20.37%40.84%37.61%
D&A (Non-Cash Add-back)
5.25M6.71M6.76M6.45M5.63M4.41M3.24M3.36M2.43M2.2M
EBIT
-90.78M-93.45M-118.32M-88.83M-129.21M-42.77M-44.11M-41.86M-2.04M-5.2M
Net Interest Income
703.1K-20K-2.4M-2.4M-5.51M-1.65M10.15M6.77M4.31M3.17M
Interest Income
0822K1.4M706K65K3.76M14.23M25.62M16.48M15.77M
Interest Expense
0842K3.8M3.11M5.57M5.41M4.08M18.84M12.17M6.13M
Other Income/Expense
3.76M5.28M36.65M-1.17M-3.92M8.95M-982.07K14.01M19.53M21.54M
Pretax Income
-87.02M▲ 0%
-88.18M▼ 1.3%
-81.67M▲ 7.4%
-87.36M▼ 7.0%
-133.34M▼ 52.6%
-33.82M▲ 74.6%
-48.19M▼ 42.5%
-42.32M▲ 12.2%
-14.21M▲ 66.4%
-7.82M▲ 0%
Pretax Margin %
-454.06%-372.78%-318.18%-290.1%-493.04%-23.45%-24.41%-17.07%-4.77%-2.03%
Income Tax
21.26M-16.55M22.26M-13.27M111.19K9.65M-4.43M-1.48M12.21M10.4M
Effective Tax Rate %
-24.43%18.77%-27.25%15.19%-0.08%-28.52%9.2%3.49%-85.94%-132.9%
Net Income
-65.76M▲ 0%
-71.63M▼ 8.9%
-103.93M▼ 45.1%
-74.09M▲ 28.7%
-133.45M▼ 80.1%
-43.46M▲ 67.4%
-43.75M▼ 0.7%
-40.81M▲ 6.7%
-26.42M▲ 35.3%
-18.82M▲ 0%
Net Margin %
-343.13%-302.82%-404.89%-246.04%-493.45%-30.13%-22.17%-16.45%-8.88%-4.88%
Net Income Growth %
-131.54%-8.93%-45.09%28.71%-80.11%67.43%-0.66%6.73%35.26%12.98%
Net Income (Continuing)
-65.76M-71.63M-103.93M-74.09M-133.45M-43.46M-43.75M-40.84M-26.42M-18.82M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-26.74▲ 0%
-2.62▲ 90.2%
-3.81▼ 45.4%
-2.33▲ 38.8%
-3.00▼ 28.8%
-0.95▲ 68.3%
-0.89▲ 6.3%
-1.02▼ 14.6%
-0.53▲ 48.0%
-0.36▲ 0%
EPS Growth %
-130.52%90.2%-45.42%38.85%-28.76%68.33%6.32%-14.61%48.04%11.2%
EPS (Basic)
-26.74-2.62-3.81-2.33-3.13-0.95-0.89-1.02-0.53-
Diluted Shares Outstanding
2.46M27.31M27.31M31.78M43.86M45.71M48.89M49.99M50.35M52.93M
Basic Shares Outstanding
2.46M27.31M27.31M31.78M42.49M45.71M48.89M49.99M50.35M50.75M
Dividend Payout Ratio
----------

IMCR Balance Sheet

Immunocore Holdings plc (IMCR) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
192.85M171.18M164.64M152.93M354.58M473.98M418.48M929.86M996.74M1B
Cash & Short-Term Investments
157.27M124.39M97.99M176.78M321.06M402.47M350.27M820.38M864.15M844.9M
Cash Only
111.42M124.39M97.99M176.78M321.06M402.47M350.27M455.73M467.71M452.68M
Short-Term Investments
45.84M000000364.64M396.44M392.22M
Accounts Receivable
5.38K4.37M66.3M2.05M33.52M57.08M48.62M83.1M73.98M81.07M
Days Sales Outstanding
0.167.49942.7924.86452.46144.4589.9122.3190.7471.13
Inventory
0-7.57M0-6.51M0692K3.56M5.45M6.74M8.25M
Days Inventory Outstanding
-----47.711.58K358.55396.03516.94
Other Current Assets
24.06M42.42M352.38K-25.9M-7.69M3.62M7.68M7.9M51.87M69.59M
Total Non-Current Assets
69.88M24.6M81.3M44.26M52.7M52.78M53.96M79.64M70.53M68.29M
Property, Plant & Equipment
32.16M20.87M72.7M36.85M42.56M38.78M33.82M47.73M50.24M49.67M
Fixed Asset Turnover
0.60x1.13x0.35x0.82x0.64x3.72x5.84x5.20x5.92x7.80x
Goodwill
0000000000
Intangible Assets
985.41K318K0004100000
Long-Term Investments
000973K222.69K137K0000
Other Non-Current Assets
36.74M2.53M6.6M4.21M6.44M8.75M11.45M17.12M20.28M18.61M
Total Assets
262.73M▲ 0%
195.78M▼ 25.5%
245.94M▲ 25.6%
197.19M▼ 19.8%
407.28M▲ 106.5%
526.76M▲ 29.3%
472.44M▼ 10.3%
1.01B▲ 113.7%
1.07B▲ 5.7%
1.07B▲ 0%
Asset Turnover
0.07x0.12x0.10x0.15x0.07x0.27x0.42x0.25x0.28x0.36x
Asset Growth %
-2.33%-25.48%25.62%-19.82%106.54%29.34%-10.31%113.68%5.72%17.42%
Total Current Liabilities
40M49.61M111.96M55M82.57M100.83M110.01M212.18M246.7M240.11M
Accounts Payable
10.81M6.44M20.84M7.88M10.12M14.45M14.08M25.1M24.36M30.16M
Days Payables Outstanding
--76.0638.45-996.236.26K1.65K1.43K2.01K
Short-Term Debt
0027.96M9.84M00002.01M2M
Deferred Revenue (Current)
0037.78M27.12M33M7.76M00583K2.33M
Other Current Liabilities
20.78M29.91M25.28M-19.8M83.68K9.15M9.18M13.1M219.74M207.39M
Current Ratio
4.82x3.45x1.47x2.78x4.29x4.70x3.80x4.38x4.04x4.18x
Quick Ratio
4.82x3.60x1.47x2.90x4.29x4.69x3.77x4.36x4.01x4.15x
Cash Conversion Cycle
------804.07-4.59K-1.17K-944.39-1.42K
Total Non-Current Liabilities
40.25M89.59M114.41M86.85M93.19M87.02M70.54M436.61M439.54M438.31M
Long-Term Debt
22.77M18.88M036.65M50.24M47.81M37.99M391.01M41.56M40.03M
Capital Lease Obligations
0050.74M25.19M34.22M31.76M27.41M40.16M042.56M
Deferred Tax Liabilities
000-24.87M000000
Other Non-Current Liabilities
17.48M70.71M139.1K25.01M76.93K2.21M773.94K0397.98M398.28M
Total Liabilities
80.25M139.19M226.37M141.85M175.76M187.86M180.55M648.79M686.24M678.42M
Total Debt
22.77M18.88M78.7M74.47M86.16M81.45M66.5M432.72M43.56M42.02M
Net Debt
-88.65M-105.51M-19.29M-102.31M-234.9M-321.02M-283.77M-23.01M-424.15M-410.65M
Debt / Equity
0.12x0.33x4.02x1.35x0.37x0.24x0.23x1.20x0.11x0.11x
Debt / EBITDA
----------1.55x
Net Debt / EBITDA
---------15.12x
Interest Coverage
--110.99x-31.17x-28.57x-23.18x-7.91x-10.81x-2.22x-0.17x-0.85x
Total Equity
182.48M▲ 0%
56.58M▼ 69.0%
19.57M▼ 65.4%
55.35M▲ 182.8%
231.53M▲ 318.3%
338.9M▲ 46.4%
291.89M▼ 13.9%
360.72M▲ 23.6%
381.03M▲ 5.6%
393.67M▲ 0%
Equity Growth %
-15.07%-68.99%-65.42%182.84%318.32%46.38%-13.87%23.58%5.63%22.78%
Book Value per Share
74.202.070.721.745.287.415.977.227.577.44
Total Shareholders' Equity
182.48M56.58M19.57M55.35M231.53M338.9M291.89M360.72M381.03M393.67M
Common Stock
00064K118.77K129K83.18K135K136K137K
Retained Earnings
-147.9M-175.18M-369.75M-349.87M-649.7M-689.39M-589.3M-795.76M-831.27M-818.3M
Treasury Stock
0000000000
Accumulated OCI
29.27M67K14.08M405.15M521.31M-54.67M-28.7M-33.76M-28.08M-35.37M
Minority Interest
0000000000

IMCR Cash Flow Statement

Immunocore Holdings plc (IMCR) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-81.9M-16.63M-101.38M-60.57M-143.11M-49.21M2.33M26.06M-7.97M-24.9M
Operating CF Margin %
-427.33%-70.29%-394.94%-201.15%-529.15%-34.12%1.18%10.51%-2.68%-
Operating CF Growth %
-80.77%79.7%-509.74%40.25%-136.25%65.61%104.73%1020.14%-130.58%-3505.92%
Net Income
-65.76M-71.63M-103.93M-74.09M-180.03M-52.54M-34.32M-51.09M-26.42M-18.82M
Depreciation & Amortization
5.51M6.71M9.21M8.98M7.59M5.33M3.24M4.2M2.43M3.36M
Stock-Based Compensation
4.33M666K3.06M8.16M48.89M32.89M25.69M34.19M028.21M
Deferred Taxes
0-16.55M-22.26M-13.27M-12.69M-3.53M0011M14.79M
Other Non-Cash Items
-3.89M-3.4M22.64M38.45M15.09M-7.19M3.14M-6.38M11.94M-19.06M
Working Capital Changes
-22.09M67.58M-10.09M-28.8M-21.96M-24.16M4.58M45.13M-6.92M-24.61M
Change in Receivables
-8.62M01.83M-532K-4.86M-26.26M-14.14M-12.35M-5.46M-16.59M
Change in Inventory
0000000000
Change in Payables
00001.47M4.91M2.08M7.27M-1.83M-193.53K
Cash from Investing
-12.92M58.01M-4.14M467K-1.28M-2.2M-4.29M-355.13M-12.16M-21.83M
Capital Expenditures
-23.52M-3.54M-4.28M-3.07M-1.39M-2.2M-3.37M-5.17M-3.23M-5.82M
CapEx % of Revenue
122.72%14.95%16.66%10.21%5.12%1.53%1.71%2.09%1.08%1.51%
Acquisitions
0000000000
Investments
----------
Other Investing
10.6M34.1M139K3.54M106K6K-925.46K44K0-1
Cash from Financing
25.64M101K55.13M115.94M288.19M145.44M27.18M343.88M9.2M10.47M
Debt Issued (Net)
24.89M0-4.04M45.13M000352.5M00
Equity Issued (Net)
0059.87M113.41M286.89M139.51M009.2M7.55M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
744.77K101K-711K-42.6M1.3M5.93M27.18M-8.62M02.93M
Net Change in Cash
-69.19M▲ 0%
41.5M▲ 160.0%
-50.42M▼ 221.5%
55.75M▲ 210.6%
144.42M▲ 159.1%
81.39M▼ 43.6%
31.78M▼ 61.0%
13.11M▼ 58.8%
8.89M▼ 32.2%
-24.17M▲ 0%
Free Cash Flow
-105.42M▲ 0%
-20.16M▲ 80.9%
-105.65M▼ 424.0%
-63.65M▲ 39.8%
-144.49M▼ 127.0%
-51.41M▲ 64.4%
-1.97M▲ 96.2%
20.89M▲ 1162.2%
-11.2M▼ 153.6%
-30.72M▲ 0%
FCF Margin %
-550.05%-85.24%-411.59%-211.36%-534.27%-35.64%-1%8.42%-3.76%-7.96%
FCF Growth %
-99.29%80.87%-423.99%39.76%-127.02%64.42%96.17%1162.18%-153.61%-217.95%
FCF per Share
-42.86-0.74-3.87-2.00-3.29-1.12-0.040.42-0.22-0.58
FCF Conversion (FCF/Net Income)
1.25x0.23x0.98x0.82x1.07x1.13x-0.05x-0.64x0.30x1.63x
Interest Paid
00005.71M4.48M0010.06M5.03M
Taxes Paid
00000765K977K510K4.64M4.61M

IMCR Key Ratios

Immunocore Holdings plc (IMCR) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-33.1%-59.93%-272.96%-197.81%-93.04%-15.24%-13.87%-12.51%-7.12%-4.83%
Return on Invested Capital (ROIC)
-94.7%-312.18%-31597.28%---442.43%-272.43%-24.41%-17.18%-40.34%
Gross Margin
100%100%-289.54%-148.42%100%96.33%99.58%97.76%97.91%98.81%
Net Margin
-343.13%-302.82%-404.89%-246.04%-493.45%-30.13%-22.17%-16.45%-8.88%-4.88%
Debt / Equity
0.12x0.33x4.02x1.35x0.37x0.24x0.23x1.20x0.11x0.11x
Interest Coverage
--110.99x-31.17x-28.57x-23.18x-7.91x-10.81x-2.22x-0.17x-0.85x
FCF Conversion
1.25x0.23x0.98x0.82x1.07x1.13x-0.05x-0.64x0.30x1.63x
Revenue Growth
-5.19%23.42%8.52%17.32%-10.19%433.32%36.85%25.63%20%15.64%
Related:IMCR Dividend History·IMCR Revenue History·IMCR Price History·IMCR P/E History·IMCR Financial Ratios·IMCR Institutional Holders

IMCR SEC Filings & Documents

Immunocore Holdings plc (IMCR) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

Feb 25, 2026·SEC

Material company update

Jan 30, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 25, 2026·SEC

FY 2025

Feb 26, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 6, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

IMCR Frequently Asked Questions

Immunocore Holdings plc (IMCR) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Immunocore Holdings plc (IMCR) reported $385.8M in revenue for fiscal year 2025. This represents a 11585% increase from $3.3M in 2013.

Immunocore Holdings plc (IMCR) grew revenue by 20.0% over the past year. This is strong growth.

Immunocore Holdings plc (IMCR) reported a net loss of $18.8M for fiscal year 2025.

Dividend & Returns

Immunocore Holdings plc (IMCR) has a return on equity (ROE) of -7.1%. Negative ROE indicates the company is unprofitable.

Immunocore Holdings plc (IMCR) had negative free cash flow of $30.7M in fiscal year 2025, likely due to heavy capital investments.

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