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IOBTIO Biotech, Inc.
$0.01$857214
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IOBT logoIO Biotech, Inc.(IOBT)Earnings, Financials & Key Ratios

IOBT•NASDAQ
$0.01
Price updated Jun 20, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutIO Biotech, Inc., a clinical-stage biopharmaceutical company, develops immune-modulating cancer therapies based on the T-win technology platform. The company's lead product candidate, IO102-IO103, which is designed to target immunosuppressive proteins, such as Indoleamine 2,3-dehydrogenase (IDO), and programmed death-ligand (PD-L1) that is in phase 2 clinical trial to treat melanoma, as well as in phase 1 clinical trial to treat lung, head and neck, bladder, and melanoma cancer. It also develops IO112, a product candidate that contains a single Arginase 1-derived peptide designed to target T cells that recognize epitopes derived from Arginase 1 for the treatment of cancers. The company was incorporated in 2014 and is based in Copenhagen, Denmark.Show more
  • Revenue$0
  • EBITDA-$94M-4.0%
  • Net Income-$95M-10.9%
  • EPS (Diluted)-1.45+26.8%
  • ROE-106%-67.5%

IOBT Price & Volume

IO Biotech, Inc. (IOBT) stock price & volume — 10-year historical chart

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Clinical Development Costs Threaten Capital Runway Sustainability

Investment Thesis • Updated 2025Q3

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial Position:Vulnerable
Cash Flow:Burning
Primary Risk:Binary clinical trial failure
"IO Biotech remains a pre-revenue, high-risk clinical-stage entity whose valuation is entirely dependent on the successful progression of its T-win platform. The company faces significant financial pressure as it burns through its remaining $30.7 million cash balance to fund intensive R&D, which reached $13.7 million in 2025Q3. Investors should monitor the high probability of future dilutive capital raises, as the current equity base has eroded to a marginal $0.9 million, leaving little room for operational error."

Verdict Logic

the company's rapid erosion of its asset base from $172.6 million to $40.0 million over two years suggests an unsustainable burn rate that necessitates immediate external financing.

IOBT Growth Metrics

IO Biotech, Inc. (IOBT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM2.2%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM1.46%

Return on Capital

10 Years-392.54%
5 Years-392.54%
3 Years-70.19%
Last Year-103.9%

Peers Comparison

Key metrics vs top competitors for IO Biotech, Inc. (IOBT)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
IOBT logoIOBTIO Biotech, Inc.Current
$0.01$857.21K-0.01——-106%—
IMVT logoIMVTImmunovant, Inc.
$38.85$7.98B-14.03——-68.16%—
NKTX logoNKTXNkarta, Inc.
$2.83$202.47M-2.01——-30.9%—
AGEN logoAGENAgenus Inc.
$3.03$126.18M-891.1810.37%52.16%——
IMCR logoIMCRImmunocore Holdings plc
$30.88$1.57B-58.2620%-4.88%-4.83%—
CLDX logoCLDXCelldex Therapeutics, Inc.
$35.26$2.35B-9.04-78.63%-34596.22%-50.72%—

Compare IOBT vs Peers

IO Biotech, Inc. (IOBT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for IOBT.

Scale Benchmark

vs MRK

Larger-name benchmark to compare IOBT against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, NKTX, AGEN, IMCR

IOBT SEC Filings & Documents

IO Biotech, Inc. (IOBT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 31, 2026·SEC

Material company update

Feb 13, 2026·SEC

Material company update

Jan 30, 2026·SEC

10-K Annual Reports

2
FY 2025

Mar 31, 2025·SEC

FY 2024

Mar 5, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 14, 2025·SEC

FY 2025

Aug 14, 2025·SEC

FY 2025

May 14, 2025·SEC

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IOBT Frequently Asked Questions

IO Biotech, Inc. (IOBT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is IOBT profitable?

IO Biotech, Inc. (IOBT) reported a net loss of $88.3M for fiscal year 2024.

Dividend & Returns
What is IOBT's return on equity?

IO Biotech, Inc. (IOBT) has a return on equity (ROE) of -106.0%. Negative ROE indicates the company is unprofitable.

What is IO Biotech, Inc.'s free cash flow?

IO Biotech, Inc. (IOBT) had negative free cash flow of $81.1M in fiscal year 2024, likely due to heavy capital investments.

What if you invested $1,000 in IOBT back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →