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IOVA
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IOVAIovance Biotherapeutics, Inc.
$10.19$4.5B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
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IOVA logo

Iovance Biotherapeutics, Inc.

IOVA
NASDAQ · Biotechnology
$10.19
At close - Sep 23, 4:00 PM EDT - USD
Market Cap$4.55B
P/E-9.3x
52W High$10.98
Volume15.29M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Commercial Ramp Accelerates Amid Persistent Cash Burn

Iovance has successfully transitioned to a commercial-stage biotech following the FDA approval of Amtagvi, with revenue surging 60.6% YoY to $263.5M TTM and reaching $99.3M in 2026Q2. However, the company remains deeply unprofitable, with operating margin at -...

GrowthAccelerating
ProfitabilityWeak
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

IOVA price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

6/12 Beats

EPS beat 6 of last 12 quarters

02

Valuation risk

-125% Peers

P/E is 125% below peer median

03

Market leadership

RS 98 · Leader

High momentum (Outperforming 98% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystEstimated earnings · Nov 6

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
IOVA+304.37%
S&P 500 (^GSPC)+12.39%
1-Year Return
IOVA+392.27%
S&P 500 (^GSPC)+15.77%
3-Year Return
IOVA+122.98%
S&P 500 (^GSPC)+81.56%
5-Year Return
IOVA-60.20%
S&P 500 (^GSPC)+64.52%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E
-9.3x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-9.3x
N/A
N/A
EV/EBITDA
N/A
N/A
N/A
Price/FCF
N/A
N/A
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$3.26-68.0%
Base (Fair)$4.82-53.0%
Bull$5.58-45.2%
$3.26 Bear$4.82 Base$5.58 Bull
Current Market Price: $10.19
Trades at a 111.4% premium to Base DCF ($4.82)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue
$264M+60.6% YoY
Net income
-$391M-5.1% YoY
Free cash flow
-$336M+7.6% YoY
Operating margin
-153.1%+87.8 pts YoY
ROIC (TTM)-48.9%
Avg ROIC 5Y-
ROE (TTM)-55.5%
Piotroski Score5 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate6/12 (50%)
Revenue Beat Rate4/12 (33%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 6, 2026
-$0.11+17.6%
vs -$0.13
$99M+13.1%
vs $88M
Q2 2026
May 7, 2026
-$0.19+0.0%
vs -$0.19
$71M-8.2%
vs $78M
Q1 2026
Feb 24, 2026
-$0.18+18.2%
vs -$0.22
$87M+7.4%
vs $81M
Q4 2025
Nov 6, 2025
-$0.25+13.8%
vs -$0.29
$67M-17.9%
vs $82M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Defense World·3d ago
Iovance Maps TIL Therapy Expansion After Record Revenue and Margin Gains

Iovance Biotherapeutics (NASDAQ: IOVA) said it is expanding its tumor-infiltrating lymphocyte, or TIL, therapy platform across multiple solid-tumor indications after reporting a record second quarter marked by nearly $100 million in revenue and a 56% margin. Speaking at the H.C. Wainwright 28th Annual Global Investment Conference, Brian Gastman, Iovance's executive vice president of translational medicine and

MarketBeat·4d ago
Iovance Maps TIL Therapy Expansion After Record Revenue and Margin Gains

Iovance Biotherapeutics NASDAQ: IOVA said it is expanding its tumor-infiltrating lymphocyte, or TIL, therapy platform across multiple solid-tumor indications after reporting a record second quarter marked by nearly $100 million in revenue and a 56% margin.

GlobeNewsWire·5d ago
Iovance Biotherapeutics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)

SAN CARLOS, Calif., Sept. 18, 2026 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA) ("Iovance" or the “Company”), a biotechnology company focused on innovating, developing, and delivering novel polyclonal tumor infiltrating lymphocyte (“TIL”) therapies for patients with cancer, today announced that on September 17, 2026 (the “Date of Grant”), the Company approved the grant of inducement stock options covering an aggregate of 179,750 shares of Iovance's common stock to eighteen new, non-executive employees.

Zacks Investment Research·5d ago
4 Biotech Stocks to Watch as Potential Takeover Targets

Biotech M&A surges in 2026, putting ABVX, IOVA, VKTX and BCRX on watchlists, as drugmakers seek late-stage and commercial assets.

Filtered for Iovance Biotherapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark IOVA against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Iovance Biotherapeutics, Inc. (IOVA)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
IOVA logoIOVAIovance Biotherapeutics, Inc.Current
$10.19$4.55B-9.3560.6%-148.38%-55.5%—
ADCT logoADCTADC Therapeutics S.A.
$1.31$166.62M-1.1714.85%-123.03%——
FATE logoFATEFate Therapeutics, Inc.
$2.43$283.24M-2.11-51.24%-1941.09%-65.08%—
CRSP logoCRSPCRISPR Therapeutics AG
$55.76$5.38B-8.62-89.97%-3368.72%-24.39%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$12.33$1.38B-3.2416.92%-672.16%-57.79%—
BEAM logoBEAMBeam Therapeutics Inc.
$24.37$2.51B-30.09120.01%-54.75%-7.7%—

Compare IOVA vs Peers

Iovance Biotherapeutics, Inc. (IOVA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ADCT

Most directly comparable listed peer for IOVA.

Scale Benchmark

vs TMO

Larger-name benchmark to compare IOVA against a more recognizable public peer.

Peer Set

Compare Top 5

vs ADCT, FATE, CRSP, NTLA

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

IOVA SEC Filings & Documents

Iovance Biotherapeutics, Inc. (IOVA) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Aug 6, 2026·SEC

Material company update

Jul 2, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 24, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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IOVA Frequently Asked Questions

Iovance Biotherapeutics, Inc. (IOVA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Iovance Biotherapeutics, Inc.'s revenue?

Iovance Biotherapeutics, Inc. (IOVA) reported $325.0M in revenue for fiscal year 2025.

How fast is Iovance Biotherapeutics, Inc. growing?

Iovance Biotherapeutics, Inc. (IOVA) grew revenue by 60.6% over the past year. This is strong growth.

Is IOVA profitable?

Iovance Biotherapeutics, Inc. (IOVA) reported a net loss of $289.5M for fiscal year 2025.

Dividend & Returns
What is IOVA's return on equity?

Iovance Biotherapeutics, Inc. (IOVA) has a return on equity (ROE) of -55.5%. Negative ROE indicates the company is unprofitable.

What is Iovance Biotherapeutics, Inc.'s free cash flow?

Iovance Biotherapeutics, Inc. (IOVA) had negative free cash flow of $296.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in IOVA back in 2008?

Total return calculator · dividends reinvested · 18+ years of data

See returns →