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Madrigal Pharmaceuticals, Inc. (MDGL) 10-Year Financial Performance & Capital Metrics

MDGL • • Industrial / General
HealthcareBiotechnologyMetabolic & Liver DiseasesNASH & Liver Diseases
AboutMadrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular, metabolic, and liver diseases. Its lead product candidate is resmetirom, a liver-directed selective thyroid hormone receptor-ß agonist, which is in Phase III clinical trials for the treatment of non-alcoholic steatohepatitis. The company also develops MGL-3745, a backup compound to resmetirom. It has research, development, and commercialization agreement with Hoffmann-La Roche. Madrigal Pharmaceuticals, Inc. is headquartered in West Conshohocken, Pennsylvania.Show more
  • Revenue $180M
  • EBITDA -$497M -30.7%
  • Net Income -$466M -24.7%
  • EPS (Diluted) -21.90 -9.6%
  • Gross Margin 96.54%
  • EBITDA Margin -275.78%
  • Operating Margin -276.39%
  • Net Margin -258.64%
  • ROE -80.35% +35.2%
  • ROIC -62.41% +63.0%
  • Debt/Equity 0.16 -45.2%
  • Interest Coverage -33.94 -13.4%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 81 (top 19%)

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 13.8% in last year
  • ✗Expensive at 14.0x book value
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM864.21%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM44.26%

EPS CAGR

10Y-
5Y-
3Y-
TTM48.13%

ROCE

10Y Avg-63.68%
5Y Avg-95.33%
3Y Avg-100.96%
Latest-71.38%

Peer Comparison

NASH & Liver Diseases
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Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+000000000180.13M
Revenue Growth %----------
Cost of Goods Sold+015677K96K112K471K00527K6.23M
COGS % of Revenue---------0.03%
Gross Profit+0-156-77K-96K-112K-471K00-527K173.9M
Gross Margin %---------0.97%
Gross Profit Growth %1%--492.59%-0.25%-0.17%-3.21%1%--330.98%
Operating Expenses+3.17M24.98M31.81M40.36M94.86M205.85M242.48M293.57M379.97M671.77M
OpEx % of Revenue---------3.73%
Selling, General & Admin13.39M9.29M7.67M14.97M22.65M21.86M37.32M48.13M108.15M435.06M
SG&A % of Revenue---------2.42%
Research & Development54.22M15.93M24.39M25.39M72.32M184.81M205.16M245.44M271.82M236.72M
R&D % of Revenue---------1.31%
Other Operating Expenses0000000000
Operating Income+-3.17M-24.98M-31.89M-40.46M-94.97M-206.32M-242.48M-293.57M-380.5M-497.88M
Operating Margin %----------2.76%
Operating Income Growth %0.96%-6.88%-0.28%-0.27%-1.35%-1.17%-0.18%-0.21%-0.3%-0.31%
EBITDA+-3.17M-24.98M-31.81M-40.36M-94.86M-205.85M-242.08M-293.1M-379.97M-496.78M
EBITDA Margin %----------2.76%
EBITDA Growth %0.96%-6.88%-0.27%-0.27%-1.35%-1.17%-0.18%-0.21%-0.3%-0.31%
D&A (Non-Cash Add-back)2.58K15677K96K112K471K405K467K527K1.1M
EBIT-3.23M-25.18M-31.15M-32.81M-83.95M-202.24M-241.85M-291.39M-360.92M-451.22M
Net Interest Income+-3.61M-1.16M558K7.67M11.02M4.33M363K-1.78M6.87M31.98M
Interest Income048.3K558K7.67M11.02M4.33M363K2.19M19.58M46.65M
Interest Expense1.06M1.16M000003.96M12.71M14.67M
Other Income/Expense-3.67M-1.41M732K7.64M11.02M4.08M636K-1.78M6.87M31.98M
Pretax Income+-68.67M-26.39M-31.15M-32.81M-83.95M-202.24M-241.85M-295.35M-373.63M-465.89M
Pretax Margin %----------2.59%
Income Tax+0000000000
Effective Tax Rate %0.1%1%1%1%1%1%1%1%1%1%
Net Income+-6.84M-26.39M-31.15M-32.81M-83.95M-202.24M-241.85M-295.35M-373.63M-465.89M
Net Margin %----------2.59%
Net Income Growth %0.92%-2.86%-0.18%-0.05%-1.56%-1.41%-0.2%-0.22%-0.27%-0.25%
Net Income (Continuing)-6.84M-26.39M-31.15M-32.81M-83.95M-202.24M-241.85M-295.35M-373.63M-465.89M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-401.56-5.07-2.54-2.22-4.73-13.09-14.63-17.23-19.99-21.90
EPS Growth %-12.11%0.99%0.5%0.13%-1.13%-1.77%-0.12%-0.18%-0.16%-0.1%
EPS (Basic)-401.56-5.07-2.54-2.22-4.73-13.09-14.63-17.23-19.99-21.90
Diluted Shares Outstanding171.01K5.21M12.24M14.8M15.39M15.45M16.54M17.14M18.69M21.27M
Basic Shares Outstanding171.01K5.21M12.24M14.8M15.39M15.45M16.54M17.14M18.69M21.27M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+363.58K41.21M192.01M485.2M440.2M285.16M271.68M361.37M637.28M1.03B
Cash & Short-Term Investments66.57M40.5M191.53M483.72M439.05M284.15M270.35M358.77M634.13M926.25M
Cash Only34.97M40.5M148.63M57.38M46.7M54M36.27M331.55M99.92M100.02M
Short-Term Investments31.61M042.9M426.34M392.35M230.15M234.08M27.23M534.22M826.23M
Accounts Receivable7.33K0000000053.82M
Days Sales Outstanding---------109.06
Inventory-7.33K0000000034.07M
Days Inventory Outstanding---------1.99K
Other Current Assets00485K1.48M1.15M002.6M3.15M18.79M
Total Non-Current Assets+420K3K301K227K1.86M1.83M1.65M1.2M3.27M9.32M
Property, Plant & Equipment420K2.95K301K227K1.86M1.83M1.65M1.2M3.27M4.59M
Fixed Asset Turnover---------39.24x
Goodwill0000000000
Intangible Assets0000000004.73M
Long-Term Investments0000000000
Other Non-Current Assets0000000000
Total Assets+68.19M41.21M192.31M485.43M442.06M287M273.33M362.57M640.55M1.04B
Asset Turnover---------0.17x
Asset Growth %-0.32%-0.4%3.67%1.52%-0.09%-0.35%-0.05%0.33%0.77%0.63%
Total Current Liabilities+49.28M4.8M10.05M8.44M25.13M46.56M76.84M115.89M118.55M169.28M
Accounts Payable102.29K762K1.93M2.49M1.18M1.02M21.38M23.83M28.04M43.6M
Days Payables Outstanding-1000K9.14K9.46K3.84K788.12--19.42K2.55K
Short-Term Debt49.1M000000000
Deferred Revenue (Current)-43K000000000
Other Current Liabilities43K001.8M2.78M4.69M6.77M14.86M17.03M34.96M
Current Ratio0.01x8.58x19.10x57.46x17.52x6.13x3.54x3.12x5.38x6.10x
Quick Ratio0.01x8.58x19.10x57.46x17.52x6.13x3.54x3.12x5.38x5.90x
Cash Conversion Cycle----------449.07
Total Non-Current Liabilities+0000361K468K387K49.29M116.67M118.59M
Long-Term Debt000000049.29M115.48M117.57M
Capital Lease Obligations0000361K468K387K01.19M1.02M
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities0000000000
Total Liabilities17.79M4.8M10.05M8.44M25.49M47.02M77.22M165.18M235.21M287.86M
Total Debt+4.65M000676K786K797K49.89M117.19M119.57M
Net Debt-30.32M-40.5M-191.53M-483.72M-46.02M-53.22M-35.47M-281.66M17.28M19.55M
Debt / Equity0.09x---0.00x0.00x0.00x0.25x0.29x0.16x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage-2.99x-21.46x------74.06x-29.93x-33.94x
Total Equity+50.41M36.41M182.26M476.98M416.56M239.97M196.11M197.39M405.33M754.38M
Equity Growth %-0.23%-0.28%4.01%1.62%-0.13%-0.42%-0.18%0.01%1.05%0.86%
Book Value per Share294.767.0014.8832.2427.0615.5411.8611.5221.6935.46
Total Shareholders' Equity50.41M36.41M182.26M476.98M416.56M239.97M196.11M197.39M405.33M754.38M
Common Stock14K1.2K1K2K2K2K2K2K2K2K
Retained Earnings-706.24M-75.31M-106.46M-139.27M-223.22M-425.46M-667.31M-962.66M-1.34B-1.8B
Treasury Stock0000000000
Accumulated OCI4K25.4K-31K-319K216K47K-80K-32K468K468K
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-71.44M-17.61M-22.32M-25.51M-41.62M-157.56M-183.92M-224.86M-324.23M-455.57M
Operating CF Margin %----------2.53%
Operating CF Growth %0.09%0.75%-0.27%-0.14%-0.63%-2.79%-0.17%-0.22%-0.44%-0.41%
Net Income-68.67M-26.39M-31.15M-32.81M-83.95M-202.24M-241.85M-295.35M-373.63M-465.89M
Depreciation & Amortization662K15677K96K112K471K405K467K527K696K
Stock-Based Compensation4.3M8.68M3.25M13.49M22.76M20.73M26.87M31.63M49.73M79.88M
Deferred Taxes00000-21.83M-7.32M000
Other Non-Cash Items3.48M1.21M2.49M13.12M021.83M7.32M797K2.41M2.09M
Working Capital Changes-7.74M-1.11M5.51M-6.28M19.45M23.48M30.65M37.6M-3.28M-72.34M
Change in Receivables38.82K7.33M0000000-53.82M
Change in Inventory0-44.72M0000000-34.07M
Change in Payables-1.84M-128.06K917K558K-1.31M-161K20.36M2.45M4.21M15.56M
Cash from Investing+20M21.99M-22.01M-380.08M30.71M159.78M-5.05M206.69M-502.52M-274.39M
Capital Expenditures-58K-3.08K-125K-22K-172K-334K-209K-217K-1.48M-1.46M
CapEx % of Revenue---------0.01%
Acquisitions----------
Investments----------
Other Investing0780.01K-21.88K3.67M0-1.92M-787K3K019.09M
Cash from Financing+40.39M14.45M173.81M314.33M235K5.09M171.24M313.45M595.12M735.06M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing0-8202.51M235K667K1.03M8.07M269.93M337.57M
Net Change in Cash----------
Free Cash Flow+-71.5M-17.61M-22.44M-25.53M-41.8M-157.9M-184.13M-225.07M-325.71M-457.03M
FCF Margin %----------2.54%
FCF Growth %0.1%0.75%-0.27%-0.14%-0.64%-2.78%-0.17%-0.22%-0.45%-0.4%
FCF per Share-418.11-3.38-1.83-1.73-2.71-10.22-11.14-13.13-17.43-21.48
FCF Conversion (FCF/Net Income)10.44x0.67x0.72x0.78x0.50x0.78x0.76x0.76x0.87x0.98x
Interest Paid0000000000
Taxes Paid0000000000

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-11.85%-60.79%-28.49%-9.95%-18.79%-61.61%-110.92%-150.12%-123.98%-80.35%
Return on Invested Capital (ROIC)-8.96%-234.17%-161.9%-13.39%-18.03%-55.53%-104.7%-576.64%-168.69%-62.41%
Gross Margin---------96.54%
Net Margin----------258.64%
Debt / Equity0.09x---0.00x0.00x0.00x0.25x0.29x0.16x
Interest Coverage-2.99x-21.46x------74.06x-29.93x-33.94x
FCF Conversion10.44x0.67x0.72x0.78x0.50x0.78x0.76x0.76x0.87x0.98x

Frequently Asked Questions

Growth & Financials

Madrigal Pharmaceuticals, Inc. (MDGL) reported $740.6M in revenue for fiscal year 2024. This represents a 9666% increase from $7.6M in 2011.

Madrigal Pharmaceuticals, Inc. (MDGL) grew revenue by 0.0% over the past year. Growth has been modest.

Madrigal Pharmaceuticals, Inc. (MDGL) reported a net loss of $289.1M for fiscal year 2024.

Dividend & Returns

Madrigal Pharmaceuticals, Inc. (MDGL) has a return on equity (ROE) of -80.3%. Negative ROE indicates the company is unprofitable.

Madrigal Pharmaceuticals, Inc. (MDGL) had negative free cash flow of $161.6M in fiscal year 2024, likely due to heavy capital investments.

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