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MDGLMadrigal Pharmaceuticals, Inc.
$399.63$9.2B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
Live BreakoutsStock ScreenerOwnership
MDGL logo

Madrigal Pharmaceuticals, Inc.

MDGL
NASDAQ · Metabolic & Cardiovascular Biotech
$399.63
At close - Nov 6, 4:00 PM EST - USD
Market Cap$9.21B
P/E-77.9x
52W High$615.00
Volume1.09M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Commercial Ramp Reaches Profitability Amid Accumulated Deficit

Madrigal's revenue has scaled from $14.6M in 2024Q2 to $431.3M in 2026Q3 with 50.1% year-over-year growth, and operating margin turned positive at 13.0%, which suggests the commercial ramp is beginning to convert into earnings.

GrowthExpanding
ProfitabilityModerate
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

MDGL price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

8/12 Beats

EPS beat 8 of last 12 quarters

02

Valuation risk

-391% Peers

P/E is 391% below peer median

03

Market leadership

RS 31 · Lag

Laggard (Underperforming 69% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 3
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

Revenue scaled from $14.6M to $431.3M over ten quarters and operating margin improved from -187.1% to 13.0%, though gross margin has eroded from 96.7% to 89.0% before recovering to 91.2%.

Analyst Consensus+71.4% target
Buy(25 analysts)
22 Buy2 Hold1 Sell

The Bull Case

Upside Catalysts

Advanced AI Integration

ChatGPT's advanced conversational capabilities can enhance Madrigal Pharmaceuticals' investor relations and data analysis.

Stock Analysis Tools

MarketBeat provides comprehensive stock analysis, price targets, and earnings estimates for informed investment decisions.

Investor Relations Resources

Madrigal Pharmaceuticals offers detailed business information for stockholders and financial analysts on its Investor Relations website.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
MDGL-32.71%
S&P 500 (^GSPC)+7.63%
1-Year Return
MDGL-18.21%
S&P 500 (^GSPC)+9.69%
3-Year Return
MDGL+171.17%
S&P 500 (^GSPC)+68.53%
5-Year Return
MDGL+335.23%
S&P 500 (^GSPC)+56.58%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E
-77.9x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-77.9x
N/A
N/A
EV/EBITDA
N/A
N/A
N/A
Price/FCF
N/A
N/A
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$18.18-95.5%
Base (Fair)$482.22+20.7%
Bull$35.12-91.2%
$18.18 Bear$482.22 Base$35.12 Bull
Current Market Price: $399.63
Trades at a 17.1% discount to Base DCF ($482.22)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$958M+432.1% YoY
Net income FY25
-$288M+38.1% YoY
Free cash flow FY25
-$190M+58.4% YoY
Operating margin FY25
-31.3%+245.1 pts YoY
ROIC (FY25)-29.4%
Avg ROIC 5Y-188.4%
ROE (TTM)-27.1%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate8/12 (67%)
Revenue Beat Rate7/12 (70%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 3, 2026
$1.83+312.0%
vs -$0.86
$431M+6.7%
vs $404M
Q3 2026
Jul 30, 2026
-$1.99+25.7%
vs -$2.68
$364M+3.5%
vs $352M
Q2 2026
May 6, 2026
-$3.25+10.0%
vs -$3.61
$311M+3.4%
vs $301M
Q1 2026
Feb 19, 2026
-$2.57-6525.0%
vs $0.04
$321M+2.8%
vs $313M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Newsfile Corp·2d ago
Kaplan Fox & Kilsheimer LLP Encourages Madrigal Pharmaceuticals, Inc. (MDGL) Investors to Contact the Firm Regarding Potential Securities Law Violations

New York, New York--(Newsfile Corp. - November 6, 2026) - Kaplan Fox & Kilsheimer LLP is investigating potential securities violations by Madrigal Pharmaceuticals, Inc. ("Madrigal" or the "Company") (NASDAQ: MDGL). CLICK HERE TO RECEIVE MORE INFORMATION ABOUT THIS INVESTIGATION If you are a Madrigal investor and have suffered losses, or if you have information that could assist in the Madrigal investigation, you may CLICK HERE to contact us.

Business Wire·2d ago
Lost Money on Madrigal Pharmaceuticals, Inc. Shares? The Law Offices of Frank R.

LOS ANGELES--(BUSINESS WIRE)--Madrigal Pharmaceuticals, Inc. ("Madrigal" or the "Company") investors who lost money may have claims to recover their losses. The Law Offices of Frank R. Cruz today announced it is investigating potential securities fraud claims on behalf of investors in Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL), examining whether the Company may have violated the federal securities laws. The investigation centers on the disclosure about Madrigal Pharmaceuticals, Inc. on Novem.

GlobeNewsWire·2d ago
Kaplan Fox & Kilsheimer LLP Encourages Investors of Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL) to Contact the Firm Regarding Potential Securities Law Violations

NEW YORK, Nov. 05, 2026 (GLOBE NEWSWIRE) -- Kaplan Fox & Kilsheimer LLP is investigating potential securities violations by Madrigal Pharmaceuticals, Inc. (“Madrigal” or the “Company”) (NASDAQ: MDGL). CLICK HERE TO RECEIVE MORE INFORMATION ABOUT THIS INVESTIGATION If you are a Madrigal investor and have suffered losses, or if you have information that could assist in the Madrigal investigation, you may CLICK HERE to contact us.

GlobeNewsWire·3d ago
Madrigal Announces New Real-World Data at AASLD 2026 Demonstrating Improvements in Liver Stiffness and Cardiometabolic Health Markers with Rezdiffra

CONSHOHOCKEN, Pa., Nov. 05, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL), a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), today announced results from multiple real-world studies of Rezdiffra presented at the American Association for the Study of Liver Diseases (AASLD) The Liver Meeting®, taking place Nov. 5–9 in Denver.

Filtered for Madrigal Pharmaceuticals, Inc.More Headlines
04

Compare before deciding

Benchmark MDGL against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Madrigal Pharmaceuticals, Inc. (MDGL)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MDGL logoMDGLMadrigal Pharmaceuticals, Inc.Current
$399.63$9.21B-77.92432.05%-10.89%-27.07%—
HIMS logoHIMSHims & Hers Health, Inc.
$26.00$5.8B-42.4259%-5.51%-30.03%—
ELVN logoELVNEnliven Therapeutics, Inc.
$49.43$3.53B-33.97——-16.91%—
GPCR logoGPCRStructure Therapeutics Inc.
$20.35$1.17B-6.87——-16.91%—
NVCR logoNVCRNovocure Ltd
$13.28$1.54B-12.748.28%-16.78%-35.81%—
HALO logoHALOHalozyme Therapeutics, Inc.
$103.63$12.29B26.1837.55%26.93%544.26%—

Compare MDGL vs Peers

Madrigal Pharmaceuticals, Inc. (MDGL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs HIMS

Most directly comparable listed peer for MDGL.

Scale Benchmark

vs LLY

Larger-name benchmark to compare MDGL against a more recognizable public peer.

Peer Set

Compare Top 5

vs HIMS, ELVN, GPCR, NVCR

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

MDGL SEC Filings & Documents

Madrigal Pharmaceuticals, Inc. (MDGL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Nov 3, 2026·SEC

Material company update

Jul 30, 2026·SEC

Material company update

Jun 17, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 19, 2026·SEC

FY 2025

Feb 26, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Nov 3, 2026·SEC

FY 2026

Jul 30, 2026·SEC

FY 2026

May 6, 2026·SEC

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MDGL Frequently Asked Questions

Madrigal Pharmaceuticals, Inc. (MDGL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Madrigal Pharmaceuticals, Inc.'s revenue?

Madrigal Pharmaceuticals, Inc. (MDGL) reported $1.43B in revenue over the trailing twelve months. Revenue was $958.4M in fiscal year 2025. That is 73397% more than the $1.3M of fiscal year 2003.

How fast is Madrigal Pharmaceuticals, Inc. growing?

Madrigal Pharmaceuticals, Inc. (MDGL) grew revenue by 92.8% over the trailing twelve months, compared with the twelve months before.

Is MDGL profitable?

No. Madrigal Pharmaceuticals, Inc. (MDGL) reported a net loss of $155.5M over the trailing twelve months.

Dividend & Returns
What is MDGL's return on equity?

Madrigal Pharmaceuticals, Inc. (MDGL) had a return on equity (ROE) of -27.1% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Madrigal Pharmaceuticals, Inc.'s free cash flow?

Madrigal Pharmaceuticals, Inc. (MDGL) had negative free cash flow of $168.7M over the trailing twelve months.

What if you invested $1,000 in MDGL back in 2003?

Total return calculator · dividends reinvested · 23+ years of data

See returns →