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MDGLMadrigal Pharmaceuticals, Inc.
$505.75$11.7B
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MDGL logoMadrigal Pharmaceuticals, Inc.(MDGL)Earnings, Financials & Key Ratios

MDGL•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryMetabolic and Obesity Therapies
AboutMadrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular, metabolic, and liver diseases. Its lead product candidate is resmetirom, a liver-directed selective thyroid hormone receptor-ß agonist, which is in Phase III clinical trials for the treatment of non-alcoholic steatohepatitis. The company also develops MGL-3745, a backup compound to resmetirom. It has research, development, and commercialization agreement with Hoffmann-La Roche. Madrigal Pharmaceuticals, Inc. is headquartered in West Conshohocken, Pennsylvania.Show more
  • Revenue$958M+432.1%
  • EBITDA-$299M+39.9%
  • Net Income-$288M+38.1%
  • EPS (Diluted)-12.85+41.3%
  • Gross Margin94.14%-2.5%
  • EBITDA Margin-31.16%+88.7%
  • Operating Margin-31.31%+88.7%
  • Net Margin-30.08%+88.4%
  • ROE-42.49%+47.1%

MDGL Key Insights

Madrigal Pharmaceuticals, Inc. (MDGL) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Expensive at 18.8x book value

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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MDGL Price & Volume

Madrigal Pharmaceuticals, Inc. (MDGL) stock price & volume — 10-year historical chart

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MDGL Growth Metrics

Madrigal Pharmaceuticals, Inc. (MDGL) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM256.82%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM20.98%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM29.09%

Return on Capital

10 Years-66.26%
5 Years-89.36%
3 Years-67.77%
Last Year-32.94%

MDGL Recent Earnings

Madrigal Pharmaceuticals, Inc. (MDGL) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 5/12 qtrs (63%)
Q2 2026Latest
May 6, 2026
Metric
Actual
Est
EPS
$3.25+10.0%
$3.61
Rev
$311M+3.4%
$301M
Q1 2026
Feb 19, 2026
Metric
Actual
Est
EPS
$2.57-6525.0%
$0.04
Rev
$321M+2.8%
$313M
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$5.08-149.4%
$2.04
Rev
$287M+17.3%
$245M
Q3 2025
Aug 5, 2025
Metric
Actual
Est
EPS
$1.90+45.4%
$3.48
Rev
$213M-12.6%
$243M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 6, 2026
$3.25vs $3.61+10.0%
$311Mvs $301M+3.4%
Q1 2026Feb 19, 2026
$2.57vs $0.04-6525.0%
$321Mvs $313M+2.8%
Q4 2025Nov 4, 2025
$5.08vs $2.04-149.4%
$287Mvs $245M+17.3%
Q3 2025Aug 5, 2025
$1.90vs $3.48+45.4%
$213Mvs $243M-12.6%
Based on last 12 quarters of dataView full earnings history →

MDGL Peer Comparison

Madrigal Pharmaceuticals, Inc. (MDGL) competitors in Metabolic and Obesity Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
AKRO logoAKROAkero Therapeutics, Inc.Direct Competitor4.5B54.65-14.57-30.58%0.05
HIMS logoHIMSHims & Hers Health, Inc.Direct Competitor7.79B35.4769.5559%-0.56%-2.48%2.34
ELVN logoELVNEnliven Therapeutics, Inc.Direct Competitor2.75B45.10-24.64-21.04%0.00
TERN logoTERNTerns Pharmaceuticals, Inc.Direct Competitor4.77B52.95-51.41-20.02%0.00
GPCR logoGPCRStructure Therapeutics Inc.Direct Competitor2.56B44.51-18.55-15.14%0.00
NVCR logoNVCRNovoCure LimitedDirect Competitor1.62B14.28-11.708.28%-25.66%-50.82%0.85
HALO logoHALOHalozyme Therapeutics, Inc.Product Competitor8.13B68.5526.7837.55%23.13%126.27%43.89
ARWR logoARWRArrowhead Pharmaceuticals, Inc.Product Competitor11.52B81.82-6706.56232.58%-48.38%-55.09%0.73

Compare MDGL vs Peers

Madrigal Pharmaceuticals, Inc. (MDGL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs AKRO

Most directly comparable listed peer for MDGL.

Scale Benchmark

vs LLY

Larger-name benchmark to compare MDGL against a more recognizable public peer.

Peer Set

Compare Top 5

vs AKRO, HIMS, ELVN, TERN

MDGL Income Statement

Madrigal Pharmaceuticals, Inc. (MDGL) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0000000180.13M958.4M1.13B
Revenue Growth %
--------432.05%256.82%
Cost of Goods Sold
77K96K112K471K0006.23M56.15M78.48M
COGS % of Revenue
-------3.46%5.86%-
Gross Profit
-77K▲ 0%
-96K▼ 24.7%
-112K▼ 16.7%
-471K▼ 320.5%
0▲ 100.0%
0▲ 0%
0▲ 0%
173.9M▲ 0%
902.25M▲ 418.8%
1.05B▲ 0%
Gross Margin %
-------96.54%94.14%93.07%
Gross Profit Growth %
-49258.97%-24.68%-16.67%-320.54%100%---418.84%-
Operating Expenses
31.81M40.36M94.86M205.85M242.48M293.57M380.5M671.77M1.2B1.37B
OpEx % of Revenue
-------372.93%125.45%-
Selling, General & Admin
7.67M14.97M22.65M21.86M37.32M48.13M108.15M435.06M813.83M914.47M
SG&A % of Revenue
-------241.52%84.91%-
Research & Development
24.39M25.39M72.32M184.81M205.16M245.44M272.35M236.72M388.52M453.05M
R&D % of Revenue
-------131.41%40.54%-
Other Operating Expenses
0000000000
Operating Income
-31.89M▲ 0%
-40.46M▼ 26.9%
-94.97M▼ 134.8%
-206.32M▼ 117.2%
-242.48M▼ 17.5%
-293.57M▼ 21.1%
-380.5M▼ 29.6%
-497.88M▼ 30.8%
-300.1M▲ 39.7%
-313.51M▲ 0%
Operating Margin %
--------276.39%-31.31%-27.68%
Operating Income Growth %
-27.64%-26.88%-134.75%-117.24%-17.53%-21.07%-29.61%-30.85%39.72%-
EBITDA
-31.81M-40.36M-94.86M-205.85M-242.08M-293.1M-379.97M-496.78M-298.59M-312.38M
EBITDA Margin %
--------275.78%-31.16%-27.58%
EBITDA Growth %
-27.33%-26.88%-135.03%-117%-17.6%-21.08%-29.64%-30.74%39.89%26.3%
D&A (Non-Cash Add-back)
77K96K112K471K405K467K527K1.1M1.51M1.13M
EBIT
-31.15M-32.81M-83.95M-202.24M-241.85M-291.39M-360.92M-451.22M-265.98M-288.76M
Net Interest Income
558K7.67M11.02M4.33M363K-1.78M6.87M31.98M15.05M8.98M
Interest Income
558K7.67M11.02M4.33M363K2.19M19.58M46.65M37.36M36.24M
Interest Expense
000003.96M12.71M14.67M22.31M11.19M
Other Income/Expense
732K7.64M11.02M4.08M636K-1.78M6.87M31.98M11.81M4.07M
Pretax Income
-31.15M▲ 0%
-32.81M▼ 5.3%
-83.95M▼ 155.9%
-202.24M▼ 140.9%
-241.85M▼ 19.6%
-295.35M▼ 22.1%
-373.63M▼ 26.5%
-465.89M▼ 24.7%
-288.28M▲ 38.1%
-309.44M▲ 0%
Pretax Margin %
--------258.64%-30.08%-27.32%
Income Tax
0000000000
Effective Tax Rate %
0%0%0%0%0%0%0%0%0%0%
Net Income
-31.15M▲ 0%
-32.81M▼ 5.3%
-83.95M▼ 155.9%
-202.24M▼ 140.9%
-241.85M▼ 19.6%
-295.35M▼ 22.1%
-373.63M▼ 26.5%
-465.89M▼ 24.7%
-288.28M▲ 38.1%
-309.44M▲ 0%
Net Margin %
--------258.64%-30.08%-27.32%
Net Income Growth %
-18.06%-5.32%-155.85%-140.92%-19.58%-22.12%-26.5%-24.69%38.12%20.98%
Net Income (Continuing)
-31.15M-32.81M-83.95M-202.24M-241.85M-295.35M-373.63M-465.89M-288.28M-309.44M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-2.54▲ 0%
-2.22▲ 12.6%
-4.73▼ 113.1%
-13.09▼ 176.7%
-14.63▼ 11.8%
-17.23▼ 17.8%
-19.99▼ 16.0%
-21.90▼ 9.6%
-12.85▲ 41.3%
-10.66▲ 0%
EPS Growth %
49.9%12.6%-113.06%-176.74%-11.76%-17.77%-16.02%-9.55%41.32%29.09%
EPS (Basic)
-2.54-2.22-4.73-13.09-14.63-17.23-19.99-21.90-12.85-
Diluted Shares Outstanding
12.24M14.8M15.39M15.45M16.54M17.14M18.69M21.27M22.43M29.03M
Basic Shares Outstanding
12.24M14.8M15.39M15.45M16.54M17.14M18.69M21.27M22.43M29.03M
Dividend Payout Ratio
----------

MDGL Balance Sheet

Madrigal Pharmaceuticals, Inc. (MDGL) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
192.01M485.2M440.2M285.16M271.68M361.37M637.28M1.03B1.25B1.18B
Cash & Short-Term Investments
191.53M483.72M439.05M284.15M270.35M358.77M634.13M926.25M983.56M817.93M
Cash Only
148.63M57.38M46.7M54M36.27M331.55M99.92M100.02M198.69M232.19M
Short-Term Investments
42.9M426.34M392.35M230.15M234.08M27.23M534.22M826.23M784.87M585.74M
Accounts Receivable
000000053.82M134.48M187.36M
Days Sales Outstanding
-------109.0651.2141.44
Inventory
000000034.07M74.84M112.07M
Days Inventory Outstanding
-------1.99K486.52371.74
Other Current Assets
485K1.48M1.15M002.6M3.15M18.79M52.89M64.95M
Total Non-Current Assets
301K227K1.86M1.83M1.65M1.2M3.27M9.32M13.82M45.02M
Property, Plant & Equipment
301K227K1.86M1.83M1.65M1.2M3.27M4.59M6.44M14.24M
Fixed Asset Turnover
-------39.24x148.87x124.27x
Goodwill
0000000000
Intangible Assets
00000004.73M7.38M7.28M
Long-Term Investments
0000000000
Other Non-Current Assets
00000000023.5M
Total Assets
192.31M▲ 0%
485.43M▲ 152.4%
442.06M▼ 8.9%
287M▼ 35.1%
273.33M▼ 4.8%
362.57M▲ 32.6%
640.55M▲ 76.7%
1.04B▲ 62.7%
1.26B▲ 20.9%
1.23B▲ 0%
Asset Turnover
-------0.17x0.76x0.93x
Asset Growth %
366.67%152.42%-8.93%-35.08%-4.76%32.65%76.67%62.71%20.85%63.27%
Total Current Liabilities
10.05M8.44M25.13M46.56M76.84M115.89M118.55M169.28M310.29M338.26M
Accounts Payable
1.93M2.49M1.18M1.02M21.38M23.83M28.04M43.6M48.88M60.8M
Days Payables Outstanding
9.14K9.46K3.84K788.12---2.55K317.74223.93
Short-Term Debt
000000001.02M1.7M
Deferred Revenue (Current)
0000000000
Other Current Liabilities
01.8M2.78M4.69M6.77M14.86M17.03M34.96M260.39M241.43M
Current Ratio
19.10x57.46x17.52x6.13x3.54x3.12x5.38x6.10x4.01x3.50x
Quick Ratio
19.10x57.46x17.52x6.13x3.54x3.12x5.38x5.90x3.77x3.16x
Cash Conversion Cycle
--------449.07219.99189.26
Total Non-Current Liabilities
00361K468K387K49.29M116.67M118.59M346.61M345.61M
Long-Term Debt
0000049.29M115.48M117.57M346.61M340.33M
Capital Lease Obligations
00361K468K387K01.19M1.02M6.73M22.11M
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
00000000-6.73M0
Total Liabilities
10.05M8.44M25.49M47.02M77.22M165.18M235.21M287.86M656.9M683.87M
Total Debt
00676K786K797K49.89M117.19M119.57M354.36M347.31M
Net Debt
-191.53M-483.72M-46.02M-53.22M-35.47M-281.66M17.28M19.55M155.67M115.12M
Debt / Equity
--0.00x0.00x0.00x0.25x0.29x0.16x0.59x0.64x
Debt / EBITDA
----------1.11x
Net Debt / EBITDA
----------0.37x
Interest Coverage
------73.51x-28.39x-30.76x-11.92x-25.80x
Total Equity
182.26M▲ 0%
476.98M▲ 161.7%
416.56M▼ 12.7%
239.97M▼ 42.4%
196.11M▼ 18.3%
197.39M▲ 0.7%
405.33M▲ 105.3%
754.38M▲ 86.1%
602.69M▼ 20.1%
543.45M▲ 0%
Equity Growth %
400.57%161.71%-12.67%-42.39%-18.28%0.65%105.35%86.11%-20.11%-81.92%
Book Value per Share
14.8832.2427.0615.5411.8611.5221.6935.4626.8618.72
Total Shareholders' Equity
182.26M476.98M416.56M239.97M196.11M197.39M405.33M754.38M602.69M543.45M
Common Stock
1K2K2K2K2K2K2K2K2K2K
Retained Earnings
-106.46M-139.27M-223.22M-425.46M-667.31M-962.66M-1.34B-1.8B-2.09B-2.18B
Treasury Stock
0000000000
Accumulated OCI
-31K-319K216K47K-80K-32K468K468K873K1.08M
Minority Interest
0000000000

MDGL Cash Flow Statement

Madrigal Pharmaceuticals, Inc. (MDGL) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-22.32M-25.51M-41.62M-157.56M-183.92M-224.86M-324.23M-455.57M-189.55M-268.1M
Operating CF Margin %
--------252.91%-19.78%-
Operating CF Growth %
-26.75%-14.29%-63.19%-278.53%-16.73%-22.26%-44.19%-40.51%58.39%168.25%
Net Income
-31.15M-32.81M-83.95M-202.24M-241.85M-295.35M-373.63M-465.89M-288.28M-309.44M
Depreciation & Amortization
77K96K112K471K405K467K527K696K4.72M3.39M
Stock-Based Compensation
3.25M13.49M22.76M20.73M26.87M31.63M49.73M79.88M98.13M85.43M
Deferred Taxes
000-21.83M-7.32M00000
Other Non-Cash Items
2.49M13.12M021.83M7.32M797K2.41M2.09M4.38M29.43M
Working Capital Changes
5.51M-6.28M19.45M23.48M30.65M37.6M-3.28M-72.34M-8.5M-76.91M
Change in Receivables
0000000-53.82M-80.65M-125.93M
Change in Inventory
0000000-34.07M-36.98M-37.99M
Change in Payables
917K558K-1.31M-161K20.36M2.45M4.21M15.56M5.28M10.41M
Cash from Investing
-22.01M-380.08M30.71M159.78M-5.05M206.69M-502.52M-274.39M32.32M60.63M
Capital Expenditures
-125K-22K-172K-334K-209K-217K-1.48M-1.46M-467K-7.32M
CapEx % of Revenue
-------0.81%0.05%0.65%
Acquisitions
0-3.67M01.92M787K-3K0000
Investments
----------
Other Investing
-21.88K3.67M0-1.92M-787K3K019.09M-8.97M0
Cash from Financing
173.81M314.33M235K5.09M171.24M313.45M595.12M735.06M255.98M249.67M
Debt Issued (Net)
0000050M65M0217.93M217.93M
Equity Issued (Net)
173.81M311.82M04.42M170.21M255.38M260.19M397.49M38.05M21.36M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
02.51M235K667K1.03M8.07M269.93M337.57M010.38M
Net Change in Cash
129.48M▲ 0%
-91.25M▼ 170.5%
-10.68M▲ 88.3%
7.31M▲ 168.4%
-17.73M▼ 342.7%
295.28M▲ 1765.0%
-231.63M▼ 178.4%
5.1M▲ 102.2%
98.76M▲ 1835.0%
43.54M▲ 0%
Free Cash Flow
-22.44M▲ 0%
-25.53M▼ 13.8%
-41.8M▼ 63.7%
-157.9M▼ 277.8%
-184.13M▼ 16.6%
-225.07M▼ 22.2%
-325.71M▼ 44.7%
-457.03M▼ 40.3%
-190.02M▲ 58.4%
-272.41M▲ 0%
FCF Margin %
--------253.72%-19.83%-24.05%
FCF Growth %
-27.43%-13.76%-63.72%-277.78%-16.61%-22.24%-44.71%-40.32%58.42%32.14%
FCF per Share
-1.83-1.73-2.71-10.22-11.14-13.13-17.43-21.48-8.47-9.38
FCF Conversion (FCF/Net Income)
0.72x0.78x0.50x0.78x0.76x0.76x0.87x0.98x0.66x0.88x
Interest Paid
0000000000
Taxes Paid
0000000000

MDGL Key Ratios

Madrigal Pharmaceuticals, Inc. (MDGL) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-28.49%-9.95%-18.79%-61.61%-110.92%-150.12%-123.98%-80.35%-42.49%-50.15%
Return on Invested Capital (ROIC)
-161.9%-13.39%-18.03%-55.53%-104.7%-576.64%-168.69%-62.41%-29.38%-34.49%
Gross Margin
-------96.54%94.14%93.07%
Net Margin
--------258.64%-30.08%-27.32%
Debt / Equity
--0.00x0.00x0.00x0.25x0.29x0.16x0.59x0.64x
Interest Coverage
------73.51x-28.39x-30.76x-11.92x-25.80x
FCF Conversion
0.72x0.78x0.50x0.78x0.76x0.76x0.87x0.98x0.66x0.88x
Revenue Growth
--------432.05%256.82%
Related:MDGL Dividend History·MDGL Revenue History·MDGL Price History·MDGL P/E History·MDGL Financial Ratios·MDGL Institutional Holders

MDGL SEC Filings & Documents

Madrigal Pharmaceuticals, Inc. (MDGL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

Apr 28, 2026·SEC

Material company update

Feb 19, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 19, 2026·SEC

FY 2025

Feb 26, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 6, 2026·SEC

FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 5, 2025·SEC

MDGL Frequently Asked Questions

Madrigal Pharmaceuticals, Inc. (MDGL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Madrigal Pharmaceuticals, Inc. (MDGL) reported $1.13B in revenue for fiscal year 2025. This represents a 86747% increase from $1.3M in 2003.

Madrigal Pharmaceuticals, Inc. (MDGL) grew revenue by 432.1% over the past year. This is strong growth.

Madrigal Pharmaceuticals, Inc. (MDGL) reported a net loss of $309.4M for fiscal year 2025.

Dividend & Returns

Madrigal Pharmaceuticals, Inc. (MDGL) has a return on equity (ROE) of -42.5%. Negative ROE indicates the company is unprofitable.

Madrigal Pharmaceuticals, Inc. (MDGL) had negative free cash flow of $272.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in MDGL back in 2003?

Total return calculator · dividends reinvested · 23+ years of data

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How much would $100/month in MDGL be worth today?

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