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MDGLMadrigal Pharmaceuticals, Inc.
$513.02$11.8B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
Live BreakoutsStock ScreenerOwnership
MDGL logo

Madrigal Pharmaceuticals, Inc.

MDGL
NASDAQ · Biotechnology
$513.02
At close - Sep 23, 4:00 PM EDT - USD
Market Cap$11.83B
P/E-39.9x
52W High$615.00
Volume315.94K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Revenue Surge Narrows Losses Amid Debt-Fueled Expansion

Madrigal Pharmaceuticals is executing a rapid commercial launch of Rezdiffra, with revenue accelerating 71.2% year-over-year to $364.3M in 2026Q2 and operating losses narrowing to -$56.3M, signaling a potential path to profitability. However, the company remai...

GrowthAccelerating
ProfitabilityStrained
ValuationReview
TechnicalsMixed
Explore valuation models
MARKET ACTION

MDGL price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

7/12 Beats

EPS beat 7 of last 12 quarters

02

Valuation risk

-217% Peers

P/E is 217% below peer median

03

Market leadership

RS 59 · Avg

Average momentum (RS Rating: 59)

04

Mixed Trend

Mixed

Price < 50DMA but > 200DMA

Next CatalystEstimated earnings · Oct 30
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

Revenue surged 71.2% year-over-year to $364.3M in 2026Q2, with gross margin at 89.0% and operating margin improving to -15.5% from -39.7% in 2025Q3, though net losses persist at -$57.9M.

Analyst Consensus+32.0% target
Buy(25 analysts)
22 Buy2 Hold1 Sell

The Bull Case

Upside Catalysts

Advanced AI Integration

ChatGPT's advanced conversational capabilities can enhance Madrigal Pharmaceuticals' investor relations and data analysis.

Stock Analysis Tools

MarketBeat provides comprehensive stock analysis, price targets, and earnings estimates for informed investment decisions.

Investor Relations Resources

Madrigal Pharmaceuticals offers detailed business information for stockholders and financial analysts on its Investor Relations website.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
MDGL-13.61%
S&P 500 (^GSPC)+12.39%
1-Year Return
MDGL+15.72%
S&P 500 (^GSPC)+15.77%
3-Year Return
MDGL+239.88%
S&P 500 (^GSPC)+78.64%
5-Year Return
MDGL+503.84%
S&P 500 (^GSPC)+54.30%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E
-39.9x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-39.9x
N/A
N/A
EV/EBITDA
N/A
N/A
N/A
Price/FCF
N/A
N/A
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$12.74-97.5%
Base (Fair)$460.08-13.4%
Bull$25.90-95.0%
$12.74 Bear$460.08 Base$25.90 Bull
Current Market Price: $513.02
Trades at a 11.5% premium to Base DCF ($460.08)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue
$958M+432.1% YoY
Net income
-$288M+38.1% YoY
Free cash flow
-$190M+58.4% YoY
Operating margin
-31.3%+245.1 pts YoY
ROIC (TTM)-29.4%
Avg ROIC 5Y-
ROE (TTM)-42.5%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate7/12 (58%)
Revenue Beat Rate6/12 (67%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Jul 30, 2026
-$1.99+25.7%
vs -$2.68
$364M+3.5%
vs $352M
Q2 2026
May 6, 2026
-$3.25+10.0%
vs -$3.61
$311M+3.4%
vs $301M
Q1 2026
Feb 19, 2026
-$2.57-6525.0%
vs $0.04
$321M+2.8%
vs $313M
Q4 2025
Nov 4, 2025
-$5.08-149.4%
vs -$2.04
$287M+17.3%
vs $245M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
GlobeNewsWire·Sep 16, 2026
Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)

CONSHOHOCKEN, Pa., Sept. 16, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), today announced that it granted equity awards on September 1, 2026 and September 14, 2026 to a total of 27 new non-executive employees as equity inducement awards under the terms of Madrigal's 2025 Inducement Plan. The equity awards were approved by Madrigal's independent Compensation Committee in accordance with Nasdaq Listing Rule 5635(c)(4).

Defense World·Sep 14, 2026
VIRGINIA RETIREMENT SYSTEMS ET Al Buys Shares of 1,800 Madrigal Pharmaceuticals, Inc. $MDGL

VIRGINIA RETIREMENT SYSTEMS ET Al purchased a new stake in shares of Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL) during the second quarter, according to the company in its most recent disclosure with the SEC. The firm purchased 1,800 shares of the biopharmaceutical company's stock, valued at approximately $967,000. A number of other large investors

Seeking Alpha·Sep 10, 2026
Madrigal Pharmaceuticals, Inc. (MDGL) Presents at 12th Annual Cantor Fitzgerald Global Healthcare Conference Transcript

Madrigal Pharmaceuticals, Inc. (MDGL) Presents at 12th Annual Cantor Fitzgerald Global Healthcare Conference Transcript

The Motley Fool·Sep 10, 2026
Institutional Investors Are Loading Up on Madrigal Pharmaceuticals Stock. Should You?

Madrigal's only commercial drug, Rezdiffra, continues to grow sales. Institutional investors hold more than 95% of the stock's float.

Filtered for Madrigal Pharmaceuticals, Inc.More Headlines
04

Compare before deciding

Benchmark MDGL against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Madrigal Pharmaceuticals, Inc. (MDGL)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MDGL logoMDGLMadrigal Pharmaceuticals, Inc.Current
$513.02$11.83B-39.92432.05%-30.08%-42.49%—
AKRO logoAKROAkero Therapeutics, Inc.
$54.65$4.5B-14.57——-30.58%—
HIMS logoHIMSHims & Hers Health, Inc.
$28.39$6.33B55.6759%-5.51%-30.03%—
ELVN logoELVNEnliven Therapeutics, Inc.
$46.09$3.29B-25.19——-18.55%—
TERN logoTERNTerns Pharmaceuticals, Inc.
$52.95$4.77B-51.41——-20.02%—
GPCR logoGPCRStructure Therapeutics Inc.
$35.95$2.07B-14.98——-16.91%—

Compare MDGL vs Peers

Madrigal Pharmaceuticals, Inc. (MDGL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs AKRO

Most directly comparable listed peer for MDGL.

Scale Benchmark

vs LLY

Larger-name benchmark to compare MDGL against a more recognizable public peer.

Peer Set

Compare Top 5

vs AKRO, HIMS, ELVN, TERN

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

MDGL SEC Filings & Documents

Madrigal Pharmaceuticals, Inc. (MDGL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 30, 2026·SEC

Material company update

Jun 17, 2026·SEC

Material company update

May 6, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 19, 2026·SEC

FY 2025

Feb 26, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Jul 30, 2026·SEC

FY 2026

May 6, 2026·SEC

FY 2025

Nov 4, 2025·SEC

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MDGL Frequently Asked Questions

Madrigal Pharmaceuticals, Inc. (MDGL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Madrigal Pharmaceuticals, Inc.'s revenue?

Madrigal Pharmaceuticals, Inc. (MDGL) reported $1.28B in revenue for fiscal year 2025. This represents a 98362% increase from $1.3M in 2003.

How fast is Madrigal Pharmaceuticals, Inc. growing?

Madrigal Pharmaceuticals, Inc. (MDGL) grew revenue by 432.1% over the past year. This is strong growth.

Is MDGL profitable?

Madrigal Pharmaceuticals, Inc. (MDGL) reported a net loss of $325.1M for fiscal year 2025.

Dividend & Returns
What is MDGL's return on equity?

Madrigal Pharmaceuticals, Inc. (MDGL) has a return on equity (ROE) of -42.5%. Negative ROE indicates the company is unprofitable.

What is Madrigal Pharmaceuticals, Inc.'s free cash flow?

Madrigal Pharmaceuticals, Inc. (MDGL) had negative free cash flow of $206.3M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in MDGL back in 2003?

Total return calculator · dividends reinvested · 23+ years of data

See returns →