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REPLReplimune Group, Inc.
$21.62$1.8B
Overview & Tools
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REPL logo

Replimune Group, Inc.

REPL
NASDAQ · Cell & Gene Therapy
$21.62
At close - Nov 6, 4:00 PM EST - USD
Market Cap$1.82B
P/E-8.4x
52W High$21.91
Volume2.97M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2027Q1

Accelerating Cash Burn Threatens Clinical Runway

Replimune is a clinical-stage biotechnology company with zero product revenue, investing heavily to advance its oncolytic virus candidate RP1 through pivotal trials.

GrowthStable
ProfitabilityNegative
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

REPL price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/12 Beats

EPS beat 5 of last 12 quarters

02

Valuation risk

-136% Peers

P/E is 136% below peer median

03

Market leadership

RS 98 · Leader

High momentum (Outperforming 98% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystEstimated earnings · Jan 28

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
REPL+142.92%
S&P 500 (^GSPC)+7.63%
1-Year Return
REPL+154.35%
S&P 500 (^GSPC)+9.69%
3-Year Return
REPL+67.99%
S&P 500 (^GSPC)+81.88%
5-Year Return
REPL-35.13%
S&P 500 (^GSPC)+67.09%

Growth & profitability

Annual revenue & EPS trend
Revenue FY26
-
Net income FY26
-$314M-26.9% YoY
Free cash flow FY26
-$285M-43.0% YoY
Operating margin FY26
-
ROIC (FY26)-106.7%
Avg ROIC 5Y-51.9%
ROE (TTM)-157.8%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/12 (42%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Oct 28, 2026
-$0.54+31.1%
vs -$0.78
—
vs $1M
Q3 2026
Aug 14, 2026
-$0.72-3.7%
vs -$0.69
—
vs $14M
Q3 2026
Jun 29, 2026
-$0.76-4.1%
vs -$0.73
—
vs $4M
Q1 2026
Feb 3, 2026
-$0.77-0.2%
vs -$0.77
—
vs $428,571
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Zacks Investment Research·5d ago
Wall Street Analysts Believe Replimune Group (REPL) Could Rally 26.8%: Here's is How to Trade

The mean of analysts' price targets for Replimune Group (REPL) points to a 26.8% upside in the stock. While this highly sought-after metric has not proven reasonably effective, strong agreement among analysts in raising earnings estimates does indicate an upside in the stock.

The Motley Fool·Oct 28, 2026
Replimune: 3 Key Takeaways for Long-Term Investors

Replimune ended the second quarter with $307.8 million in cash. Over 15 institutions wrote prescriptions within 20 business days.

Seeking Alpha·Oct 28, 2026
Replimune Group, Inc. (REPL) Q2 2027 Earnings Call Transcript

Replimune Group, Inc. ( REPL ) Q2 2027 Earnings Call October 28, 2026 8:00 AM EDT Company Participants Arleen Goldenberg Sushil Patel - CEO & Director Michelle DiNapoli - Chief Commercial Officer Emily Hill - Chief Financial Officer Conference Call Participants Evan Seigerman - BMO Capital Markets Equity Research Allison Bratzel - Piper Sandler & Co., Research Division Anupam Rama - JPMorgan Chase & Co, Research Division Jiale Song - Jefferies LLC, Research Division Mubeen Mosaheb Romy O'Connor - Van Lanschot Kempen NV Presentation Operator Good day, and thank you for standing by. Welcome to the Replimune's Second Quarter Fiscal 2027 Earnings Conference Call.

GlobeNewsWire·Oct 28, 2026
Replimune Reports Fiscal Second Quarter 2027 Financial Results and Provides Corporate Update

TUDRIQEV first delivered to patients for advanced melanoma on October 6th More than 15 institutions have prescribed TUDRIQEV Management will host a webcast today at 8:00 a.m. ET WOBURN, Mass.

Filtered for Replimune Group, Inc.More Headlines
04

Compare before deciding

Benchmark REPL against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Replimune Group, Inc. (REPL)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
REPL logoREPLReplimune Group, Inc.Current
$21.62$1.82B-8.39——-157.78%—
AMGN logoAMGNAmgen Inc.
$460.42$248.49B26.779.92%24.12%85.59%2.05%
IMVT logoIMVTImmunovant, Inc.
$30.53$6.3B-11.66—-7585.86%-69.59%—
CGEN logoCGENCompugen Ltd.
$1.96$185.32M5.27161.14%47.55%42.57%—
IOVA logoIOVAIovance Biotherapeutics, Inc.
$8.04$3.59B-16.6260.6%-58.19%-29.71%—
NKTR logoNKTRNektar Therapeutics
$37.26$1.23B-7.84-43.89%-287.84%-37.99%—

Compare REPL vs Peers

Replimune Group, Inc. (REPL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs AMGN

Most directly comparable listed peer for REPL.

Scale Benchmark

vs MRK

Larger-name benchmark to compare REPL against a more recognizable public peer.

Peer Set

Compare Top 5

vs AMGN, IMVT, CGEN, IOVA

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

REPL SEC Filings & Documents

Replimune Group, Inc. (REPL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 14, 2026·SEC

Material company update

Aug 10, 2026·SEC

Material company update

Aug 7, 2026·SEC

10-K Annual Reports

3
FY 2026

Jun 29, 2026·SEC

FY 2025

May 22, 2025·SEC

FY 2024

May 16, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 14, 2026·SEC

FY 2026

Feb 3, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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REPL Frequently Asked Questions

Replimune Group, Inc. (REPL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is REPL profitable?

No. Replimune Group, Inc. (REPL) reported a net loss of $271.0M over the trailing twelve months.

Dividend & Returns
What is REPL's return on equity?

Replimune Group, Inc. (REPL) had a return on equity (ROE) of -157.8% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Replimune Group, Inc.'s free cash flow?

Replimune Group, Inc. (REPL) had negative free cash flow of $245.8M over the trailing twelve months.

What if you invested $1,000 in REPL back in 2017?

Total return calculator · dividends reinvested · 9+ years of data

See returns →