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SOPH logoSOPHiA GENETICS S.A.(SOPH)Earnings, Financials & Key Ratios

SOPH•NASDAQ
$5.02
$360M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryHealthcare ITSub-IndustryLife Sciences and Precision Medicine Software
AboutSOPHiA GENETICS SA operates as a healthcare technology company. The company offers SOPHiA DDM platform, a cloud-based software-as-a-service platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM platform and related solutions, products, and services are used by hospital, laboratory, and biopharma worldwide. SOPHiA GENETICS SA was incorporated in 2011 and is headquartered in Saint-Sulpice, Switzerland.Show more
  • Revenue$77M+18.6%
  • EBITDA-$61M-5.9%
  • Net Income-$79M-26.4%
  • EPS (Diluted)-1.17-23.2%
  • Gross Margin61.88%-8.2%
  • EBITDA Margin-79.46%+10.7%
  • Operating Margin-91.79%+10.1%
  • Net Margin-102.24%-6.6%
  • ROE-110%-118.2%
  • ROIC-123.46%-15.1%
  • Debt/Equity1.34+329.5%
  • Interest Coverage-15.57+49.8%
Technical→

SOPH Key Insights

SOPHiA GENETICS S.A. (SOPH) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 80 (top 20%)
  • ✓Strong 5Y sales CAGR of 22.2%

✗Weaknesses

  • ✗Profits declining 15.0% over 5 years
  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

SOPH Price & Volume

SOPHiA GENETICS S.A. (SOPH) stock price & volume — 10-year historical chart

Loading chart...

SOPH Growth Metrics

SOPHiA GENETICS S.A. (SOPH) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years22.16%
3 Years17.56%
TTM18.56%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-26.41%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-23.16%

Return on Capital

10 Years-51.99%
5 Years-42.4%
3 Years-47.3%
Last Year-58.75%

SOPH Recent Earnings

SOPHiA GENETICS S.A. (SOPH) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (33%)●Beat Revenue 4/12 qtrs (33%)
Q2 2026Latest
May 5, 2026
EPS
$0.27
Est $0.23
-16.1%
Revenue
$22M
Est $20M
+6.3%
Q2 2026
Mar 3, 2026
EPS
$0.28
Est $0.24
-17.9%
Revenue
$22M
Est $20M
+5.9%
Q4 2025
Nov 4, 2025
EPS
$0.30
Est $0.20
-50.0%
Revenue
$19M
Est $20M
-5.0%
Q3 2025
Aug 5, 2025
EPS
$0.33
Est $0.21
+257.1%
Revenue
$18M
Est $18M
-0.2%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$0.27vs $0.23-16.1%
$22Mvs $20M+6.3%
Q2 2026Mar 3, 2026
$0.28vs $0.24-17.9%
$22Mvs $20M+5.9%
Q4 2025Nov 4, 2025
$0.30vs $0.20-50.0%
$19Mvs $20M-5.0%
Q3 2025Aug 5, 2025
$0.33vs $0.21+257.1%
$18Mvs $18M-0.2%
Based on last 12 quarters of dataView full earnings history →

SOPH Peer Comparison

SOPHiA GENETICS S.A. (SOPH) competitors in Life Sciences and Precision Medicine Software — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
NTRA logoNTRANatera, Inc.Direct Competitor29.58B215.09-140.5856.75%-14.61%-24.69%0.16
EXAS logoEXASExact Sciences CorporationDirect Competitor20.02B104.91-95.3717.69%-6.4%-8.66%1.05
VCYT logoVCYTVeracyte, Inc.Direct Competitor3.29B41.1950.2316.01%16.25%6.86%0.03
CDNA logoCDNACareDx, IncDirect Competitor1.08B20.94-52.3513.79%-1.98%-2.61%0.06
ILMN logoILMNIllumina, Inc.Product Competitor21.66B142.5826.16-0.78%19.43%32.84%0.94
PACB logoPACBPacific Biosciences of California, Inc.Product Competitor516.17M1.71-1.60-23.19%-325.8%-13.95%1.33
FLGT logoFLGTFulgent Genetics, Inc.Product Competitor443.83M14.92-7.5713.83%-18.75%-5.42%0.00
TMO logoTMOThermo Fisher Scientific Inc.Supply Chain175.76B472.9526.663.91%15.18%13.23%0.76

Compare SOPH vs Peers

SOPHiA GENETICS S.A. (SOPH) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NTRA

Most directly comparable listed peer for SOPH.

Scale Benchmark

vs TMO

Larger-name benchmark to compare SOPH against a more recognizable public peer.

Peer Set

Compare Top 5

vs NTRA, EXAS, VCYT, CDNA

SOPH Income Statement

SOPHiA GENETICS S.A. (SOPH) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue25.36M28.4M40.45M47.56M62.37M65.17M77.27M
Revenue Growth %-11.98%42.43%17.58%31.14%4.49%18.56%
Cost of Goods Sold7.53M10.71M15.23M16.31M19.46M21.24M29.46M
COGS % of Revenue29.7%37.71%37.65%34.29%31.2%32.58%38.12%
Gross Profit
17.83M▲ 0%
17.69M▼ 0.8%
25.22M▲ 42.6%
31.25M▲ 23.9%
42.91M▲ 37.3%
43.94M▲ 2.4%
47.81M▲ 8.8%
Gross Margin %70.3%62.29%62.35%65.71%68.8%67.42%61.88%
Gross Profit Growth %--0.78%42.56%23.92%37.3%2.39%8.82%
Operating Expenses50.12M55.08M96.71M119.08M117.74M110.5M118.74M
OpEx % of Revenue197.61%193.94%239.09%250.37%188.77%169.56%153.67%
Selling, General & Admin35.08M36.4M70.24M84.08M81.72M76.32M85.17M
SG&A % of Revenue138.33%128.16%173.65%176.79%131.03%117.11%110.23%
Research & Development15.02M18.59M26.58M35.37M36.97M34.37M33.57M
R&D % of Revenue59.21%65.45%65.71%74.37%59.27%52.73%43.44%
Other Operating Expenses16K93K-108K-377K-954K-183K0
Operating Income
-32.29M▲ 0%
-37.39M▼ 15.8%
-71.49M▼ 91.2%
-87.82M▼ 22.8%
-74.83M▲ 14.8%
-66.57M▲ 11.0%
-70.92M▼ 6.5%
Operating Margin %-127.3%-131.64%-176.73%-184.66%-119.97%-102.14%-91.79%
Operating Income Growth %--15.8%-91.21%-22.85%14.8%11.04%-6.55%
EBITDA-30.37M-35M-67.88M-82.25M-66.49M-57.97M-61.4M
EBITDA Margin %-119.76%-123.23%-167.81%-172.94%-106.6%-88.95%-79.46%
EBITDA Growth %--15.22%-93.96%-21.17%19.16%12.81%-5.91%
D&A (Non-Cash Add-back)1.91M2.39M3.61M5.57M8.34M8.6M9.53M
EBIT-32.65M-40.38M-72.85M-86.95M-77.91M-59.36M-70.92M
Net Interest Income-890K-744K-638K685K3.96M1.45M-2.68M
Interest Income86K96K20K1.32M4.55M3.36M1.87M
Interest Expense976K840K658K639K588K1.91M4.55M
Other Income/Expense-1.34M-3.84M-2.02M238K-3.67M5.3M-7.56M
Pretax Income
-33.63M▲ 0%
-41.23M▼ 22.6%
-73.51M▼ 78.3%
-87.58M▼ 19.2%
-78.5M▲ 10.4%
-61.27M▲ 21.9%
-78.49M▼ 28.1%
Pretax Margin %-132.6%-145.16%-181.72%-184.16%-125.85%-94.01%-101.57%
Income Tax162K-1.89M168K-136K486K1.22M512K
Effective Tax Rate %-0.48%4.57%-0.23%0.16%-0.62%-2%-0.65%
Net Income
-33.79M▲ 0%
-39.34M▼ 16.4%
-73.67M▼ 87.3%
-87.45M▼ 18.7%
-78.98M▲ 9.7%
-62.49M▲ 20.9%
-79M▼ 26.4%
Net Margin %-133.23%-138.52%-182.14%-183.87%-126.63%-95.89%-102.24%
Net Income Growth %--16.42%-87.28%-18.7%9.68%20.88%-26.41%
Net Income (Continuing)-33.79M-39.34M-73.67M-87.45M-78.98M-62.49M-79M
Discontinued Operations0000000
Minority Interest0000000
EPS (Diluted)
-0.53▲ 0%
-0.82▼ 54.7%
-1.33▼ 62.2%
-1.36▼ 2.3%
-1.22▲ 10.3%
-0.95▲ 22.1%
-1.17▼ 23.2%
EPS Growth %--54.72%-62.2%-2.26%10.29%22.13%-23.16%
EPS (Basic)-0.53-0.82-1.33-1.36-1.22-0.95-1.17
Diluted Shares Outstanding63.86M48.02M55.3M64.1M64.75M65.78M67.54M
Basic Shares Outstanding63.86M48.02M55.3M64.1M64.75M65.78M67.54M
Dividend Payout Ratio-------

SOPH Balance Sheet

SOPHiA GENETICS S.A. (SOPH) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets33.76M109.69M282.86M196.25M148.05M99.41M99.08M
Cash & Short-Term Investments18.43M97.34M265.32M178.61M123.25M80.23M70.29M
Cash Only18.07M74.63M192.96M161.31M123.25M80.23M70.29M
Short-Term Investments366K22.72M72.36M17.31M000
Accounts Receivable9.71M7.85M7.09M8.05M15.21M8.69M18.53M
Days Sales Outstanding139.67100.9463.9761.888.9848.6787.51
Inventory3.61M3.38M5.73M5.16M6.48M5.87M6.35M
Days Inventory Outstanding174.94115.34137.31115.41121.59100.8678.69
Other Current Assets339K27K775K731K345K835K758K
Total Non-Current Assets17.9M22.42M37.32M47.58M58.11M55.9M64.38M
Property, Plant & Equipment6.45M5.54M15.96M21.4M23.1M19.38M18.05M
Fixed Asset Turnover3.93x5.13x2.54x2.22x2.70x3.36x4.28x
Goodwill7.83M8.6M8.3M8.19M9M8.34M9.56M
Intangible Assets2.4M4.68M7.38M11.78M18.19M20.66M26.34M
Long-Term Investments373K775K00001.98M
Other Non-Current Assets839K711K3.7M4.28M6.1M5.76M6.21M
Total Assets
51.66M▲ 0%
132.12M▲ 155.8%
320.17M▲ 142.3%
243.84M▼ 23.8%
206.16M▼ 15.5%
155.31M▼ 24.7%
163.46M▲ 5.2%
Asset Turnover0.49x0.21x0.13x0.20x0.30x0.42x0.47x
Asset Growth %-155.76%142.34%-23.84%-15.45%-24.66%5.24%
Total Current Liabilities19.26M21.59M28.6M26.81M35.62M26.8M50.53M
Accounts Payable1.73M1.28M2.34M2.17M2.26M1.93M5.32M
Days Payables Outstanding83.7943.6656.0148.5742.3233.2165.86
Short-Term Debt2.23M2.87M00002.7M
Deferred Revenue (Current)2.1M2.64M4.07M3.43M9.49M5.73M16.72M
Other Current Liabilities5.73M5.25M9.16M10.27M13.58M11.22M5.32M
Current Ratio1.75x5.08x9.89x7.32x4.16x3.71x1.96x
Quick Ratio1.57x4.92x9.69x7.13x3.97x3.49x1.84x
Cash Conversion Cycle230.82172.62145.26128.64168.25116.32100.35
Total Non-Current Liabilities10.14M10.02M16.17M16.9M19.09M32.02M65.78M
Long-Term Debt1.61M457K00013.24M47.73M
Capital Lease Obligations3.66M2.88M11.25M14.05M15.67M14.6M12.59M
Deferred Tax Liabilities000000424K
Other Non-Current Liabilities4.79M6.54M4.92M2.85M3.42M4.18M5.04M
Total Liabilities29.4M31.61M44.77M43.71M54.71M58.82M116.31M
Total Debt8.46M7.25M13.06M16.74M18.6M30.03M63.02M
Net Debt-9.61M-67.38M-179.9M-144.56M-104.65M-50.2M-7.27M
Debt / Equity0.38x0.07x0.05x0.08x0.12x0.31x1.34x
Debt / EBITDA-------
Net Debt / EBITDA-------
Interest Coverage-33.46x-48.08x-110.71x-136.07x-132.49x-31.03x-15.57x
Total Equity
22.25M▲ 0%
100.51M▲ 351.7%
275.4M▲ 174.0%
200.13M▼ 27.3%
151.44M▼ 24.3%
96.49M▼ 36.3%
47.15M▼ 51.1%
Equity Growth %-351.67%174%-27.33%-24.33%-36.29%-51.14%
Book Value per Share0.352.094.983.122.341.470.70
Total Shareholders' Equity22.25M100.51M275.4M200.13M151.44M96.49M47.15M
Common Stock1.95M2.46M3.33M3.46M4.05M4.19M4.81M
Retained Earnings-98.34M-137.68M-211.35M-298.8M-377.78M-440.28M-519.28M
Treasury Stock000-117K-646K-702K-1.22M
Accumulated OCI-581K8.3M12.54M23.96M53.98M61.04M89.15M
Minority Interest0000000

SOPH Cash Flow Statement

SOPHiA GENETICS S.A. (SOPH) cash flow — operating, investing & free cash flow history

Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-31.68M-31.73M-57.94M-70.09M-48.58M-42.82M-38.01M
Operating CF Margin %-124.91%-111.73%-143.24%-147.38%-77.88%-65.71%-49.19%
Operating CF Growth %--0.16%-82.6%-20.98%30.7%11.84%11.23%
Net Income-33.63M-41.23M-73.51M-87.58M-78.5M-61.27M-79M
Depreciation & Amortization1.91M2.39M3.61M5.57M8.34M8.6M9.53M
Stock-Based Compensation717K1.36M8.51M13.61M15.24M16.49M0
Deferred Taxes-447K-763K-1.6M-1.29M-1.13M-726K0
Other Non-Cash Items1.39M2.69M-1.08M873K6.6M-3.33M20.75M
Working Capital Changes-1.62M3.82M6.12M-1.27M872K-2.58M10.71M
Change in Receivables-4.35M1.12M1.81M1.33M-6.5M5.89M-6.6M
Change in Inventory-862K536K-2.34M-200K-874K69K46K
Change in Payables5.6M-185K8.98M-1.43M6.87M-7.38M16.93M
Cash from Investing-3.03M-24.32M-56.93M41.97M8.32M-8.18M-10.51M
Capital Expenditures-1.35M-450K-6.67M-4.1M-1.49M-244K-8.62M
CapEx % of Revenue5.34%1.58%16.49%8.61%2.4%0.37%11.16%
Acquisitions003.99M0000
Investments-------
Other Investing-1.68M-2.75M-3.99M-6.28M-7.73M-7.93M0
Cash from Financing-1.02M107.05M237.77M-1.57M-2.82M11.59M34.13M
Debt Issued (Net)-2.78M-1.67M-4.08M-2.32M-3.04M11.18M32.69M
Equity Issued (Net)0107.64M231.31M00405K1.44M
Dividends Paid0000000
Share Repurchases0000000
Other Financing1.76M1.07M10.55M748K226K00
Net Change in Cash
-35.84M▲ 0%
56.56M▲ 257.8%
118.34M▲ 109.2%
-31.66M▼ 126.8%
-38.05M▼ 20.2%
-43.02M▼ 13.1%
-9.94M▲ 76.9%
Free Cash Flow
-34.71M▲ 0%
-34.93M▼ 0.6%
-64.61M▼ 84.9%
-80.47M▼ 24.6%
-57.8M▲ 28.2%
-51M▲ 11.8%
-38.59M▲ 24.3%
FCF Margin %-136.87%-123.01%-159.73%-169.21%-92.67%-78.25%-49.93%
FCF Growth %--0.64%-84.95%-24.55%28.17%11.77%24.34%
FCF per Share-0.54-0.73-1.17-1.26-0.89-0.78-0.57
FCF Conversion (FCF/Net Income)0.94x0.81x0.79x0.80x0.62x0.69x0.48x
Interest Paid0000000
Taxes Paid0000000

SOPH Key Ratios

SOPHiA GENETICS S.A. (SOPH) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2019202020212022202320242025
Return on Equity (ROE)-151.85%-64.09%-39.2%-36.78%-44.93%-50.41%-110%
Return on Invested Capital (ROIC)-191.46%-122.49%-83.37%-87.2%-109.65%-107.27%-123.46%
Gross Margin70.3%62.29%62.35%65.71%68.8%67.42%61.88%
Net Margin-133.23%-138.52%-182.14%-183.87%-126.63%-95.89%-102.24%
Debt / Equity0.38x0.07x0.05x0.08x0.12x0.31x1.34x
Interest Coverage-33.46x-48.08x-110.71x-136.07x-132.49x-31.03x-15.57x
FCF Conversion0.94x0.81x0.79x0.80x0.62x0.69x0.48x
Revenue Growth-11.98%42.43%17.58%31.14%4.49%18.56%

SOPH Frequently Asked Questions

SOPHiA GENETICS S.A. (SOPH) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

SOPHiA GENETICS S.A. (SOPH) reported $77.3M in revenue for fiscal year 2025. This represents a 205% increase from $25.4M in 2019.

SOPHiA GENETICS S.A. (SOPH) grew revenue by 18.6% over the past year. This is strong growth.

SOPHiA GENETICS S.A. (SOPH) reported a net loss of $79.0M for fiscal year 2025.

Dividend & Returns

SOPHiA GENETICS S.A. (SOPH) has a return on equity (ROE) of -110.0%. Negative ROE indicates the company is unprofitable.

SOPHiA GENETICS S.A. (SOPH) had negative free cash flow of $40.6M in fiscal year 2025, likely due to heavy capital investments.

Explore More SOPH

SOPHiA GENETICS S.A. (SOPH) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

→

Earnings History

EPS trends, net income & profitability

→

Price History

Long-term charts & historical price data

→

Revenue History

Sales growth patterns & revenue breakdown

→

Financial Ratios

30 years of market, efficiency and balance-sheet ratios

→

Valuation

DCF intrinsic value, peer multiples & estimates

→
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