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SOPHSOPHiA GENETICS S.A.
$5.98$429M
Overview & Verdict
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SOPH logoSOPHiA GENETICS S.A.(SOPH)Earnings, Financials & Key Ratios

SOPH•NASDAQ
$5.75
Price updated Jun 27, 2026
SectorHealthcareIndustryHealthcare ITSub-IndustryLife Sciences and Precision Medicine Software
AboutSOPHiA GENETICS SA operates as a healthcare technology company. The company offers SOPHiA DDM platform, a cloud-based software-as-a-service platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM platform and related solutions, products, and services are used by hospital, laboratory, and biopharma worldwide. SOPHiA GENETICS SA was incorporated in 2011 and is headquartered in Saint-Sulpice, Switzerland.Show more
  • Revenue$77M+18.6%
  • EBITDA-$61M-5.9%
  • Net Income-$79M-26.4%
  • EPS (Diluted)-1.17-23.2%
  • Gross Margin61.88%-8.2%
  • EBITDA Margin-79.46%+10.7%
  • Operating Margin-91.79%+10.1%
  • Net Margin-102.24%-6.6%
  • ROE-110%-118.2%

SOPH Price & Volume

SOPHiA GENETICS S.A. (SOPH) stock price & volume — 10-year historical chart

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Accelerating Revenue Growth Faces Severe Liquidity Constraints

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Accelerating
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Insufficient liquidity for operations

Key Thesis Takeaways

  • SOPHiA GENETICS demonstrates promising top-line momentum with 22.0% year-over-year revenue growth in 2026Q1, yet the firm remains trapped in a cycle of persistent operating losses and capital erosion.
  • While the platform-agnostic diagnostic model continues to scale, the company's inability to achieve operating leverage—evidenced by a -79.7% operating margin—creates a precarious financial outlook.
  • Investors should remain cautious as the firm's cash balance of $65.4M against a TTM operating loss of $70.9M suggests an urgent need for external financing to sustain operations.

Verdict Logic

the company's cash position of $65.4M is insufficient to cover its ongoing operating losses, creating a high risk of dilution or insolvency.

SOPH Growth Metrics

SOPHiA GENETICS S.A. (SOPH) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years22.16%
3 Years17.56%
TTM20.85%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-22.31%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-18%

Return on Capital

10 Years-51.99%
5 Years-42.4%
3 Years-47.3%
Last Year-58.75%

SOPH Recent Earnings

SOPHiA GENETICS S.A. (SOPH) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (33%)●Beat Revenue 4/12 qtrs (33%)
Q2 2026Latest
May 5, 2026
Metric
Actual
Est
EPS
$0.27-16.1%
$0.23
Rev
$22M+6.3%
$20M
Q2 2026
Mar 3, 2026
Metric
Actual
Est
EPS
$0.28-17.9%
$0.24
Rev
$22M+5.9%
$20M
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$0.30-50.0%
$0.20
Rev
$19M-5.0%
$20M
Q3 2025
Aug 5, 2025
Metric
Actual
Est
EPS
$0.33+257.1%
$0.21
Rev
$18M-0.2%
$18M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$0.27vs $0.23-16.1%
$22Mvs $20M+6.3%
Q2 2026Mar 3, 2026
$0.28vs $0.24-17.9%
$22Mvs $20M+5.9%
Q4 2025Nov 4, 2025
$0.30vs $0.20-50.0%
$19Mvs $20M-5.0%
Q3 2025Aug 5, 2025
$0.33vs $0.21+257.1%
$18Mvs $18M-0.2%
Based on last 12 quarters of dataView full earnings history →

Latest SOPH News

Recent stock market news and headlines for SOPHiA GENETICS S.A. (SOPH)

PRNewsWire·Jun 22, 2026
SOPHiA GENETICS Publishes Results of the 2026 Annual General Meeting

Shareholders adopt all proposals, co-founder Dr. Jurgi Camblong elected as Executive Chairman of the Board, Ross Muken elected as new member of the Board ahead of his appointment as CEO effective July 1, 2026 ROLLE, Switzerland, June 22, 2026 /PRNewswire/ -- SOPHiA GENETICS (Nasdaq: SOPH), a global leader in Ai-driven precision medicine, today announced that its 2026 Annual General Meeting of shareholders adopted all proposals on the agenda, electing Dr. Jurgi Camblong as the Executive Chairman of the Board of Directors with 99.79% of the votes, and Ross Muken as a member of the Board of Directors for the first time with 99.88% of the votes. Mr. Muken will assume the role of Chief Executive Officer, effective July 1, 2026.

PRNewsWire·Jun 19, 2026
SOPHiA GENETICS Announces Closing of $57.5 Million Public Offering of Ordinary Shares With Full Exercise of the Underwriters' Option to Purchase Additional Shares

BOSTON and ROLLE, Switzerland, June 19, 2026 /PRNewswire/ -- SOPHiA GENETICS (Nasdaq: SOPH), a global leader in Ai-driven precision medicine, announced today the closing of its previously announced underwritten public offering with total gross proceeds of $57.5 million, before deducting the underwriting discounts and commissions and estimated offering expenses payable by the Company. As a result of strong investor demand, the offering was oversubscribed, and the underwriters fully exercised their option to purchase an additional 1,578,900 ordinary shares at the public offering price, less the underwriting discounts and commissions.

Seeking Alpha·Jun 18, 2026
SOPHiA Genetics: Strong Growth Meets A Critical Execution Phase

SOPHiA GENETICS is approaching an inflection point in precision medicine, leveraging AI-driven genomic analysis as sequencing costs decline and data complexity rises. SOPH's platform benefits from a self-reinforcing data flywheel, with 2.5 million genomic profiles and 537 institutions using SOPHiA DDM across 75 countries. Revenue grew 22% year-over-year to $21.7M in 1Q26, with 117% net dollar retention and adjusted gross margin of 75.4%, but profitability remains a key watchpoint.

Benzinga·Jun 17, 2026
Sophia Genetics, Ormat Technologies And Other Big Stocks Moving Lower In Wednesday's Pre-Market Session

U.S. stock futures were mostly higher this morning, with the Nasdaq futures gaining over 100 points on Wednesday.

GuruFocus·Jun 17, 2026
SOPHiA GENETICS Announces Pricing of $50 Million Public Offering of Ordinary Shares

SOPHiA GENETICS Announces Pricing of $50 Million Public Offering of Ordinary Shares PR Newswire BOSTON and ROLLE

Peers Comparison

Key metrics vs top competitors for SOPHiA GENETICS S.A. (SOPH)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
SOPH logoSOPHSOPHiA GENETICS S.A.Current
$5.75$412.1M-4.9118.56%-102.24%-110%—
NTRA logoNTRANatera, Inc.
$261.91$37.51B-172.3135.9%-9.05%-15.13%—
EXAS logoEXASExact Sciences Corporation
$104.91$20.02B-95.3717.69%-6.4%-8.66%—
VCYT logoVCYTVeracyte, Inc.
$60.49$4.83B73.7716.01%16.25%6.86%—
CDNA logoCDNACareDx, Inc
$28.82$1.49B-72.0513.79%-1.98%-2.61%—
ILMN logoILMNIllumina, Inc.
$176.55$26.82B32.39-0.78%19.43%32.84%—

Compare SOPH vs Peers

SOPHiA GENETICS S.A. (SOPH) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NTRA

Most directly comparable listed peer for SOPH.

Scale Benchmark

vs TMO

Larger-name benchmark to compare SOPH against a more recognizable public peer.

Peer Set

Compare Top 5

vs NTRA, EXAS, VCYT, CDNA

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SOPH Frequently Asked Questions

SOPHiA GENETICS S.A. (SOPH) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is SOPHiA GENETICS S.A.'s revenue?

SOPHiA GENETICS S.A. (SOPH) reported $81.2M in revenue for fiscal year 2025. This represents a 220% increase from $25.4M in 2019.

How fast is SOPHiA GENETICS S.A. growing?

SOPHiA GENETICS S.A. (SOPH) grew revenue by 18.6% over the past year. This is strong growth.

Is SOPH profitable?

SOPHiA GENETICS S.A. (SOPH) reported a net loss of $80.9M for fiscal year 2025.

Dividend & Returns
What is SOPH's return on equity?

SOPHiA GENETICS S.A. (SOPH) has a return on equity (ROE) of -110.0%. Negative ROE indicates the company is unprofitable.

What is SOPHiA GENETICS S.A.'s free cash flow?

SOPHiA GENETICS S.A. (SOPH) had negative free cash flow of $45.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in SOPH back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →