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SOPH logoSOPHiA GENETICS S.A.(SOPH)Earnings, Financials & Key Ratios

SOPH•NASDAQ
$5.40
$387M mkt cap·Price updated May 7, 2026
SectorHealthcareIndustryHealthcare ITSub-IndustryLife Sciences and Precision Medicine Software
AboutSOPHiA GENETICS SA operates as a healthcare technology company. The company offers SOPHiA DDM platform, a cloud-based software-as-a-service platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM platform and related solutions, products, and services are used by hospital, laboratory, and biopharma worldwide. SOPHiA GENETICS SA was incorporated in 2011 and is headquartered in Saint-Sulpice, Switzerland.Show more
  • Revenue$77M+18.6%
  • EBITDA-$61M-5.9%
  • Net Income-$79M-26.4%
  • EPS (Diluted)-1.17-23.2%
  • Gross Margin61.88%-8.2%
  • EBITDA Margin-79.46%+10.7%
  • Operating Margin-91.79%+10.1%
  • Net Margin-102.24%-6.6%
  • ROE-110%-118.2%
  • ROIC-123.46%-15.1%
  • Debt/Equity1.34+329.5%
  • Interest Coverage-15.57+49.8%
Technical→

SOPH Key Insights

SOPHiA GENETICS S.A. (SOPH) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 80 (top 20%)
  • ✓Strong 5Y sales CAGR of 22.2%

✗Weaknesses

  • ✗Profits declining 15.0% over 5 years
  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

SOPH Price & Volume

SOPHiA GENETICS S.A. (SOPH) stock price & volume — 10-year historical chart

Loading chart...

SOPH Growth Metrics

SOPHiA GENETICS S.A. (SOPH) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years22.16%
3 Years17.56%
TTM20.85%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-22.31%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-18%

Return on Capital

10 Years-51.99%
5 Years-42.4%
3 Years-47.3%
Last Year-58.75%

SOPH Recent Earnings

SOPHiA GENETICS S.A. (SOPH) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (33%)●Beat Revenue 4/12 qtrs (33%)
Q2 2026Latest
May 5, 2026
EPS
$0.27
Est $0.23
-16.1%
Revenue
$22M
Est $20M
+6.3%
Q2 2026
Mar 3, 2026
EPS
$0.28
Est $0.24
-17.9%
Revenue
$22M
Est $20M
+5.9%
Q4 2025
Nov 4, 2025
EPS
$0.30
Est $0.20
-50.0%
Revenue
$19M
Est $20M
-5.0%
Q3 2025
Aug 5, 2025
EPS
$0.33
Est $0.21
+257.1%
Revenue
$18M
Est $18M
-0.2%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$0.27vs $0.23-16.1%
$22Mvs $20M+6.3%
Q2 2026Mar 3, 2026
$0.28vs $0.24-17.9%
$22Mvs $20M+5.9%
Q4 2025Nov 4, 2025
$0.30vs $0.20-50.0%
$19Mvs $20M-5.0%
Q3 2025Aug 5, 2025
$0.33vs $0.21+257.1%
$18Mvs $18M-0.2%
Based on last 12 quarters of dataView full earnings history →

SOPH Peer Comparison

SOPHiA GENETICS S.A. (SOPH) competitors in Life Sciences and Precision Medicine Software — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
NTRA logoNTRANatera, Inc.Direct Competitor31.16B219.82-144.6235.9%-9.03%-15.28%0.13
EXAS logoEXASExact Sciences CorporationDirect Competitor20.02B104.91-95.3717.69%-6.4%-8.66%1.05
VCYT logoVCYTVeracyte, Inc.Direct Competitor3.25B40.7649.7116.01%16.25%6.86%0.03
CDNA logoCDNACareDx, IncDirect Competitor1.11B21.44-53.6013.79%-1.98%-2.61%0.06
ILMN logoILMNIllumina, Inc.Product Competitor21.07B138.7125.45-0.78%19.43%32.84%0.94
PACB logoPACBPacific Biosciences of California, Inc.Product Competitor498.3M1.65-0.913.89%-341.47%-11.23%141.98
FLGT logoFLGTFulgent Genetics, Inc.Product Competitor449.48M15.11-7.6713.83%-18.75%-5.42%0.00
TMO logoTMOThermo Fisher Scientific Inc.Supply Chain176.36B474.5626.753.91%15.18%13.23%0.76

Compare SOPH vs Peers

SOPHiA GENETICS S.A. (SOPH) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NTRA

Most directly comparable listed peer for SOPH.

Scale Benchmark

vs TMO

Larger-name benchmark to compare SOPH against a more recognizable public peer.

Peer Set

Compare Top 5

vs NTRA, EXAS, VCYT, CDNA

SOPH Income Statement

SOPHiA GENETICS S.A. (SOPH) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue25.36M28.4M40.45M47.56M62.37M65.17M77.27M81.18M
Revenue Growth %-11.98%42.43%17.58%31.14%4.49%18.56%20.85%
Cost of Goods Sold7.53M10.71M15.23M16.31M19.46M21.24M29.46M26.56M
COGS % of Revenue29.7%37.71%37.65%34.29%31.2%32.58%38.12%-
Gross Profit
17.83M▲ 0%
17.69M▼ 0.8%
25.22M▲ 42.6%
31.25M▲ 23.9%
42.91M▲ 37.3%
43.94M▲ 2.4%
47.81M▲ 8.8%
54.62M▲ 0%
Gross Margin %70.3%62.29%62.35%65.71%68.8%67.42%61.88%67.28%
Gross Profit Growth %--0.78%42.56%23.92%37.3%2.39%8.82%-
Operating Expenses50.12M55.08M96.71M119.08M117.74M110.5M118.74M126.37M
OpEx % of Revenue197.61%193.94%239.09%250.37%188.77%169.56%153.67%-
Selling, General & Admin35.08M36.4M70.24M84.08M81.72M76.32M85.17M91.67M
SG&A % of Revenue138.33%128.16%173.65%176.79%131.03%117.11%110.23%-
Research & Development15.02M18.59M26.58M35.37M36.97M34.37M33.57M35.89M
R&D % of Revenue59.21%65.45%65.71%74.37%59.27%52.73%43.44%-
Other Operating Expenses16K93K-108K-377K-954K-183K0-1000K
Operating Income
-32.29M▲ 0%
-37.39M▼ 15.8%
-71.49M▼ 91.2%
-87.82M▼ 22.8%
-74.83M▲ 14.8%
-66.57M▲ 11.0%
-70.92M▼ 6.5%
-71.75M▲ 0%
Operating Margin %-127.3%-131.64%-176.73%-184.66%-119.97%-102.14%-91.79%-88.39%
Operating Income Growth %--15.8%-91.21%-22.85%14.8%11.04%-6.55%-
EBITDA-30.37M-35M-67.88M-82.25M-66.49M-57.97M-61.4M-63.1M
EBITDA Margin %-119.76%-123.23%-167.81%-172.94%-106.6%-88.95%-79.46%-77.73%
EBITDA Growth %--15.22%-93.96%-21.17%19.16%12.81%-5.91%-14.69%
D&A (Non-Cash Add-back)1.91M2.39M3.61M5.57M8.34M8.6M9.53M8.65M
EBIT-32.65M-40.38M-72.85M-86.95M-77.91M-59.36M-70.92M-74.76M
Net Interest Income-890K-744K-638K685K3.96M1.45M-2.68M-3.85M
Interest Income86K96K20K1.32M4.55M3.36M1.87M1.09M
Interest Expense976K840K658K639K588K1.91M4.55M4.94M
Other Income/Expense-1.34M-3.84M-2.02M238K-3.67M5.3M-7.56M-7.92M
Pretax Income
-33.63M▲ 0%
-41.23M▼ 22.6%
-73.51M▼ 78.3%
-87.58M▼ 19.2%
-78.5M▲ 10.4%
-61.27M▲ 21.9%
-78.49M▼ 28.1%
-79.67M▲ 0%
Pretax Margin %-132.6%-145.16%-181.72%-184.16%-125.85%-94.01%-101.57%-98.14%
Income Tax162K-1.89M168K-136K486K1.22M512K1.26M
Effective Tax Rate %-0.48%4.57%-0.23%0.16%-0.62%-2%-0.65%-1.58%
Net Income
-33.79M▲ 0%
-39.34M▼ 16.4%
-73.67M▼ 87.3%
-87.45M▼ 18.7%
-78.98M▲ 9.7%
-62.49M▲ 20.9%
-79M▼ 26.4%
-80.94M▲ 0%
Net Margin %-133.23%-138.52%-182.14%-183.87%-126.63%-95.89%-102.24%-99.7%
Net Income Growth %--16.42%-87.28%-18.7%9.68%20.88%-26.41%-22.31%
Net Income (Continuing)-33.79M-39.34M-73.67M-87.45M-78.98M-62.49M-79M-80.94M
Discontinued Operations00000000
Minority Interest00000000
EPS (Diluted)
-0.53▲ 0%
-0.82▼ 54.7%
-1.33▼ 62.2%
-1.36▼ 2.3%
-1.22▲ 10.3%
-0.95▲ 22.1%
-1.17▼ 23.2%
-1.14▲ 0%
EPS Growth %--54.72%-62.2%-2.26%10.29%22.13%-23.16%-18%
EPS (Basic)-0.53-0.82-1.33-1.36-1.22-0.95-1.17-
Diluted Shares Outstanding63.86M48.02M55.3M64.1M64.75M65.78M67.54M71.14M
Basic Shares Outstanding63.86M48.02M55.3M64.1M64.75M65.78M67.54M71.14M
Dividend Payout Ratio--------

SOPH Balance Sheet

SOPHiA GENETICS S.A. (SOPH) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets33.76M109.69M282.86M196.25M148.05M99.41M99.08M95.81M
Cash & Short-Term Investments18.43M97.34M265.32M178.61M123.25M80.23M70.29M65.39M
Cash Only18.07M74.63M192.96M161.31M123.25M80.23M70.29M65.39M
Short-Term Investments366K22.72M72.36M17.31M0000
Accounts Receivable9.71M7.85M7.09M8.05M15.21M8.69M18.53M14.31M
Days Sales Outstanding139.67100.9463.9761.888.9848.6787.5157.1
Inventory3.61M3.38M5.73M5.16M6.48M5.87M6.35M7.09M
Days Inventory Outstanding174.94115.34137.31115.41121.59100.8678.6990.47
Other Current Assets339K27K775K731K345K835K758K9.02M
Total Non-Current Assets17.9M22.42M37.32M47.58M58.11M55.9M64.38M61.18M
Property, Plant & Equipment6.45M5.54M15.96M21.4M23.1M19.38M18.05M16.8M
Fixed Asset Turnover3.93x5.13x2.54x2.22x2.70x3.36x4.28x4.58x
Goodwill7.83M8.6M8.3M8.19M9M8.34M9.56M35.82M
Intangible Assets2.4M4.68M7.38M11.78M18.19M20.66M26.34M0
Long-Term Investments373K775K00001.98M1.98M
Other Non-Current Assets839K711K3.7M4.28M6.1M5.76M6.21M27.27M
Total Assets
51.66M▲ 0%
132.12M▲ 155.8%
320.17M▲ 142.3%
243.84M▼ 23.8%
206.16M▼ 15.5%
155.31M▼ 24.7%
163.46M▲ 5.2%
157M▲ 0%
Asset Turnover0.49x0.21x0.13x0.20x0.30x0.42x0.47x0.49x
Asset Growth %-155.76%142.34%-23.84%-15.45%-24.66%5.24%2.36%
Total Current Liabilities19.26M21.59M28.6M26.81M35.62M26.8M50.53M46.59M
Accounts Payable1.73M1.28M2.34M2.17M2.26M1.93M5.32M12.67M
Days Payables Outstanding83.7943.6656.0148.5742.3233.2165.86121.67
Short-Term Debt2.23M2.87M00002.7M2.71M
Deferred Revenue (Current)2.1M2.64M4.07M3.43M9.49M5.73M16.72M42.31M
Other Current Liabilities5.73M5.25M9.16M10.27M13.58M11.22M5.32M15.27M
Current Ratio1.75x5.08x9.89x7.32x4.16x3.71x1.96x1.96x
Quick Ratio1.57x4.92x9.69x7.13x3.97x3.49x1.84x1.84x
Cash Conversion Cycle230.82172.62145.26128.64168.25116.32100.3525.9
Total Non-Current Liabilities10.14M10.02M16.17M16.9M19.09M32.02M65.78M64.71M
Long-Term Debt1.61M457K00013.24M47.73M47.84M
Capital Lease Obligations3.66M2.88M11.25M14.05M15.67M14.6M12.59M51.5M
Deferred Tax Liabilities000000424K424K
Other Non-Current Liabilities4.79M6.54M4.92M2.85M3.42M4.18M5.04M20.23M
Total Liabilities29.4M31.61M44.77M43.71M54.71M58.82M116.31M111.31M
Total Debt8.46M7.25M13.06M16.74M18.6M30.03M63.02M62.42M
Net Debt-9.61M-67.38M-179.9M-144.56M-104.65M-50.2M-7.27M-2.97M
Debt / Equity0.38x0.07x0.05x0.08x0.12x0.31x1.34x1.34x
Debt / EBITDA--------0.99x
Net Debt / EBITDA-------0.05x
Interest Coverage-33.46x-48.08x-110.71x-136.07x-132.49x-31.03x-15.57x-15.13x
Total Equity
22.25M▲ 0%
100.51M▲ 351.7%
275.4M▲ 174.0%
200.13M▼ 27.3%
151.44M▼ 24.3%
96.49M▼ 36.3%
47.15M▼ 51.1%
45.69M▲ 0%
Equity Growth %-351.67%174%-27.33%-24.33%-36.29%-51.14%-181.16%
Book Value per Share0.352.094.983.122.341.470.700.64
Total Shareholders' Equity22.25M100.51M275.4M200.13M151.44M96.49M47.15M45.69M
Common Stock1.95M2.46M3.33M3.46M4.05M4.19M4.81M4.81M
Retained Earnings-98.34M-137.68M-211.35M-298.8M-377.78M-440.28M-519.28M-538.6M
Treasury Stock000-117K-646K-702K-1.22M-1.01M
Accumulated OCI-581K8.3M12.54M23.96M53.98M61.04M89.15M92.06M
Minority Interest00000000

SOPH Cash Flow Statement

SOPHiA GENETICS S.A. (SOPH) cash flow — operating, investing & free cash flow history

Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations-31.68M-31.73M-57.94M-70.09M-48.58M-42.82M-38.01M-38.01M
Operating CF Margin %-124.91%-111.73%-143.24%-147.38%-77.88%-65.71%-49.19%-
Operating CF Growth %--0.16%-82.6%-20.98%30.7%11.84%11.23%-36.47%
Net Income-33.63M-41.23M-73.51M-87.58M-78.5M-61.27M-79M-80.94M
Depreciation & Amortization1.91M2.39M3.61M5.57M8.34M8.6M9.53M9.98M
Stock-Based Compensation717K1.36M8.51M13.61M15.24M16.49M08.5M
Deferred Taxes-447K-763K-1.6M-1.29M-1.13M-726K0-356K
Other Non-Cash Items1.39M2.69M-1.08M873K6.6M-3.33M20.75M12.65M
Working Capital Changes-1.62M3.82M6.12M-1.27M872K-2.58M10.71M7.28M
Change in Receivables-4.35M1.12M1.81M1.33M-6.5M5.89M-6.6M-3.43M
Change in Inventory-862K536K-2.34M-200K-874K69K46K-1.78M
Change in Payables5.6M-185K8.98M-1.43M6.87M-7.38M16.93M12.45M
Cash from Investing-3.03M-24.32M-56.93M41.97M8.32M-8.18M-10.51M-10.93M
Capital Expenditures-1.35M-450K-6.67M-4.1M-1.49M-244K-8.62M-5.59M
CapEx % of Revenue5.34%1.58%16.49%8.61%2.4%0.37%11.16%-
Acquisitions003.99M00000
Investments--------
Other Investing-1.68M-2.75M-3.99M-6.28M-7.73M-7.93M0-3.89M
Cash from Financing-1.02M107.05M237.77M-1.57M-2.82M11.59M34.13M46.34M
Debt Issued (Net)-2.78M-1.67M-4.08M-2.32M-3.04M11.18M32.69M-1.41M
Equity Issued (Net)0107.64M231.31M00405K1.44M16.25M
Dividends Paid00000000
Share Repurchases00000000
Other Financing1.76M1.07M10.55M748K226K0031.5M
Net Change in Cash
-35.84M▲ 0%
56.56M▲ 257.8%
118.34M▲ 109.2%
-31.66M▼ 126.8%
-38.05M▼ 20.2%
-43.02M▼ 13.1%
-9.94M▲ 76.9%
-3.14M▲ 0%
Free Cash Flow
-34.71M▲ 0%
-34.93M▼ 0.6%
-64.61M▼ 84.9%
-80.47M▼ 24.6%
-57.8M▲ 28.2%
-51M▲ 11.8%
-38.59M▲ 24.3%
-45.43M▲ 0%
FCF Margin %-136.87%-123.01%-159.73%-169.21%-92.67%-78.25%-49.93%-55.96%
FCF Growth %--0.64%-84.95%-24.55%28.17%11.77%24.34%2.59%
FCF per Share-0.54-0.73-1.17-1.26-0.89-0.78-0.57-0.57
FCF Conversion (FCF/Net Income)0.94x0.81x0.79x0.80x0.62x0.69x0.48x0.56x
Interest Paid00000001.56M
Taxes Paid00000000

SOPH Key Ratios

SOPHiA GENETICS S.A. (SOPH) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric202020212022202320242025TTM
Return on Equity (ROE)-64.09%-39.2%-36.78%-44.93%-50.41%-110%-140.63%
Return on Invested Capital (ROIC)-122.49%-83.37%-87.2%-109.65%-107.27%-123.46%-123.46%
Gross Margin62.29%62.35%65.71%68.8%67.42%61.88%67.28%
Net Margin-138.52%-182.14%-183.87%-126.63%-95.89%-102.24%-99.7%
Debt / Equity0.07x0.05x0.08x0.12x0.31x1.34x1.34x
Interest Coverage-48.08x-110.71x-136.07x-132.49x-31.03x-15.57x-15.13x
FCF Conversion0.81x0.79x0.80x0.62x0.69x0.48x0.56x
Revenue Growth11.98%42.43%17.58%31.14%4.49%18.56%20.85%

SOPH Frequently Asked Questions

SOPHiA GENETICS S.A. (SOPH) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

SOPHiA GENETICS S.A. (SOPH) reported $81.2M in revenue for fiscal year 2025. This represents a 220% increase from $25.4M in 2019.

SOPHiA GENETICS S.A. (SOPH) grew revenue by 18.6% over the past year. This is strong growth.

SOPHiA GENETICS S.A. (SOPH) reported a net loss of $80.9M for fiscal year 2025.

Dividend & Returns

SOPHiA GENETICS S.A. (SOPH) has a return on equity (ROE) of -110.0%. Negative ROE indicates the company is unprofitable.

SOPHiA GENETICS S.A. (SOPH) had negative free cash flow of $45.4M in fiscal year 2025, likely due to heavy capital investments.

Explore More SOPH

SOPHiA GENETICS S.A. (SOPH) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

→

Price History

Long-term charts & historical price data

→

Revenue History

Sales growth patterns & revenue breakdown

→

Financial Ratios

30 years of market, efficiency and balance-sheet ratios

→

Valuation

DCF intrinsic value, peer multiples & estimates

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