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TLPH
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TLPHTalphera, Inc.
$1.05$54M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
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TLPH logo

Talphera, Inc.

TLPH
NASDAQ · Metabolic & Cardiovascular Biotech
$1.05
At close - Nov 6, 4:00 PM EST - USD
Market Cap$54M
P/E-5.3x
52W High$1.57
Volume79.29K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Talphera Faces Critical Liquidity and Clinical Hurdles

Talphera is currently a pre-commercial entity undergoing a high-risk strategic pivot toward the Niyad platform, characterized by a complete evaporation of revenue and persistent quarterly operating losses exceeding $3 million.

GrowthContracting
ProfitabilityNegative
ValuationReview
TechnicalsMixed
Explore valuation models
MARKET ACTION

TLPH price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

10/12 Beats

EPS beat 10 of last 12 quarters

02

Valuation risk

-120% Peers

P/E is 120% below peer median

03

Market leadership

RS 64 · Avg

Average momentum (RS Rating: 64)

04

Mixed Trend

Mixed

Price < 50DMA but > 200DMA

Next CatalystConfirmed earnings · Nov 12

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
TLPH-9.48%
S&P 500 (^GSPC)+7.63%
1-Year Return
TLPH-9.48%
S&P 500 (^GSPC)+9.69%
3-Year Return
TLPH+110.00%
S&P 500 (^GSPC)+75.87%
5-Year Return
TLPH-93.90%
S&P 500 (^GSPC)+60.00%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E5Y Low
-5.3x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-5.3x
0.4x
0th· Low
EV/EBITDA
N/A
N/A
N/A
Price/FCF
N/A
N/A
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
No DCF Model AvailableIntrinsic value modeling is not supported for this equity.

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$28K
Net income FY25
-$14M-9.9% YoY
Free cash flow FY25
-$11M+10.4% YoY
Operating margin FY25
-48157.1%
ROIC (FY25)-86.8%
Avg ROIC 5Y-110.8%
ROE (TTM)-87.3%
Piotroski Score6 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate10/12 (83%)
Revenue Beat Rate0/12 (0%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 13, 2026
-$0.06+4.0%
vs -$0.06
—
vs —
Q2 2026
May 13, 2026
-$0.04+42.9%
vs -$0.07
—
vs —
Q2 2026
Mar 23, 2026
-$0.06+20.0%
vs -$0.07
—
vs $580,000
Q4 2025
Nov 12, 2025
-$0.11-46.7%
vs -$0.07
$1,000
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Defense World·Oct 6, 2026
Head to Head Comparison: ANI Pharmaceuticals (NASDAQ:ANIP) and Talphera (NASDAQ:TLPH)

Talphera (NASDAQ: TLPH - Get Free Report) and ANI Pharmaceuticals (NASDAQ: ANIP - Get Free Report) are both small-cap healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their risk, analyst recommendations, profitability, institutional ownership, earnings, valuation and dividends. Analyst Recommendations This is a summary of current

Zacks Investment Research·Sep 21, 2026
Talphera (TLPH) Upgraded to Buy: Here's What You Should Know

Talphera (TLPH) has been upgraded to a Zacks Rank #2 (Buy), reflecting growing optimism about the company's earnings prospects. This might drive the stock higher in the near term.

PRNewsWire·Sep 3, 2026
Talphera to Participate in the H.C. Wainwright 28th Annual Global Investment Conference

SAN MATEO, Calif., Sept. 3, 2026 /PRNewswire/ -- Talphera, Inc. (Nasdaq: TLPH), ("Talphera"), a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings, today announced that Company management will be presenting at the H.C.

Seeking Alpha·Aug 13, 2026
Talphera, Inc. (TLPH) Q2 2026 Earnings Call Transcript

Talphera, Inc. (TLPH) Q2 2026 Earnings Call Transcript

Filtered for Talphera, Inc.More Headlines
04

Compare before deciding

Benchmark TLPH against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Talphera, Inc. (TLPH)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
TLPH logoTLPHTalphera, Inc.Current
$1.05$54.49M-5.26—-1507600%-87.28%—
PRGO logoPRGOPerrigo Company plc
$15.85$2.19B-1.25-2.75%-43.27%-68.13%7.26%
HALO logoHALOHalozyme Therapeutics, Inc.
$103.63$12.29B26.1837.55%26.93%544.26%—
NKTR logoNKTRNektar Therapeutics
$37.26$1.23B-7.84-43.89%-287.84%-37.99%—
PCRX logoPCRXPacira BioSciences, Inc.
$36.43$1.43B39.433.63%5.08%5.53%—
INVA logoINVAInnoviva, Inc.
$19.10$1.41B7.1218.52%43.79%15.84%—

Compare TLPH vs Peers

Talphera, Inc. (TLPH) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PRGO

Most directly comparable listed peer for TLPH.

Scale Benchmark

vs MCK

Larger-name benchmark to compare TLPH against a more recognizable public peer.

Peer Set

Compare Top 5

vs PRGO, HALO, NKTR, PCRX

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

TLPH SEC Filings & Documents

Talphera, Inc. (TLPH) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 12, 2026·SEC

Material company update

Jun 23, 2026·SEC

Material company update

May 13, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 23, 2026·SEC

FY 2025

Mar 31, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 12, 2026·SEC

FY 2026

May 13, 2026·SEC

FY 2025

Nov 12, 2025·SEC

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TLPH Frequently Asked Questions

Talphera, Inc. (TLPH) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Talphera, Inc.'s revenue?

Talphera, Inc. (TLPH) reported $0.0M in revenue over the trailing twelve months. Revenue was $0.0M in fiscal year 2025.

How fast is Talphera, Inc. growing?

Talphera, Inc. (TLPH) revenue fell by 96.3% over the trailing twelve months, compared with the twelve months before.

Is TLPH profitable?

No. Talphera, Inc. (TLPH) reported a net loss of $15.1M over the trailing twelve months.

Dividend & Returns
What is TLPH's return on equity?

Talphera, Inc. (TLPH) had a return on equity (ROE) of -87.3% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Talphera, Inc.'s free cash flow?

Talphera, Inc. (TLPH) had negative free cash flow of $12.3M over the trailing twelve months.

What if you invested $1,000 in TLPH back in 2008?

Total return calculator · dividends reinvested · 18+ years of data

See returns →