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Talphera, Inc. (TLPH) 10-Year Financial Performance & Capital Metrics

TLPH • • Industrial / General
HealthcareSpecialty & Generic PharmaSpecialty PharmaceuticalsCardiovascular & Metabolic
AboutTalphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. Its lead product candidate is Niyad, a lyophilized formulation of nafamostat, which is under an investigational device exemption as an anticoagulant for the extracorporeal circuit. It is also developing LTX-608, an anti-inflammatory and antiviral potential for the treatment of multiple conditions, including COVID-19, disseminated intravascular coagulation (DIC), acute respiratory distress syndrome (ARDS), and acute pancreatitis; Fedsyra, a pre-filled ephedrine syringe; and PFS-02, a pre-filled phenylephrine syringe. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. Talphera, Inc. was incorporated in 2005 and is headquartered in San Mateo, California.Show more
  • Revenue $0 -100.0%
  • EBITDA -$15M +9.7%
  • Net Income -$13M +29.3%
  • EPS (Diluted) -0.50 +61.2%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -117.65% -14.9%
  • ROIC -162.84% -60.4%
  • Debt/Equity 0.82
  • Interest Coverage -38.71 +69.3%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 83 (top 17%)

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Shares diluted 81.2% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-90.04%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM20.85%

EPS CAGR

10Y-
5Y-
3Y-
TTM44.93%

ROCE

10Y Avg-51.21%
5Y Avg-61.42%
3Y Avg-69.58%
Latest-96.92%

Peer Comparison

Cardiovascular & Metabolic
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
CRDLCardiol Therapeutics Inc.96.3M0.96-1.89-337.72%0.01
TLPHTalphera, Inc.46.14M0.99-1.98-100%-442.43%-64.6%0.82
ESPREsperion Therapeutics, Inc.742.03M3.13-11.18185.66%-34.84%
RMTIRockwell Medical, Inc.37.44M0.95-37.7021.38%-7.3%-14.9%8.52%0.42

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+19.26M17.36M8M2.15M2.29M5.42M378K0651K0
Revenue Growth %2.69%-0.1%-0.54%-0.73%0.06%1.37%-0.93%-1%--1%
Cost of Goods Sold+24.26M12.31M10.66M3.98M6.81M6.03M3.01M1.65M5.55M6.72M
COGS % of Revenue1.26%0.71%1.33%1.85%2.97%1.11%7.95%-8.52%-
Gross Profit+-5M5.04M-2.66M-1.82M-4.52M-616K-2.63M-1.65M-4.89M-6.72M
Gross Margin %-0.26%0.29%-0.33%-0.85%-1.97%-0.11%-6.95%--7.52%-
Gross Profit Growth %0.74%2.01%-1.53%0.31%-1.48%0.86%-3.27%0.37%-1.97%-0.37%
Operating Expenses+13.32M37M36.02M33.9M49.69M40.35M15.49M18.7M11.99M8.53M
OpEx % of Revenue0.69%2.13%4.51%15.76%21.71%7.45%40.97%-18.42%-
Selling, General & Admin14.2M15.6M16.61M20.77M45.03M36.33M017.01M00
SG&A % of Revenue0.74%0.9%2.08%9.65%19.67%6.71%----
Research & Development22.49M21.4M19.41M13.14M4.66M4.02M2.44M1.69M5.55M6.72M
R&D % of Revenue1.17%1.23%2.43%6.11%2.04%0.74%6.44%-8.52%-
Other Operating Expenses00000013.05M06.45M1.82M
Operating Income+-19.2M-31.96M-38.68M-35.73M-54.2M-40.96M-18.12M-20.35M-16.89M-15.25M
Operating Margin %-1%-1.84%-4.84%-16.61%-23.68%-7.56%-47.93%--25.94%-
Operating Income Growth %0.49%-0.66%-0.21%0.08%-0.52%0.24%0.56%-0.12%0.17%0.1%
EBITDA+-17.21M-29.91M-36.94M-35.15M-52.54M-39.11M-16.14M-18.7M-16.79M-15.16M
EBITDA Margin %-0.89%-1.72%-4.62%-16.34%-22.95%-7.22%-42.71%--25.8%-
EBITDA Growth %0.53%-0.74%-0.24%0.05%-0.49%0.26%0.59%-0.16%0.1%0.1%
D&A (Non-Cash Add-back)1.98M2.05M1.74M575K1.67M1.85M1.97M1.65M96K96K
EBIT-18.23M-31.04M-38.17M-34.59M-50.7M-37.07M-18.12M60.25M-16.89M-15.25M
Net Interest Income+-3.69M-11.23M-13.53M-11.42M968K588K871K386K6.6M-394K
Interest Income1.72M918K510K1.14M3.5M3.89M3.16M1.5M6.74M0
Interest Expense5.41M12.15M14.04M12.56M2.54M3.31M2.29M1.12M134K394K
Other Income/Expense-4.44M-11.23M-13.53M-11.42M968K588K969K79.49M6.6M2.25M
Pretax Income+-23.64M-43.19M-52.21M-47.15M-53.24M-40.38M-17.15M59.14M-10.29M-13M
Pretax Margin %-1.23%-2.49%-6.53%-21.92%-23.26%-7.45%-45.36%--15.8%-
Income Tax+760K-34K-701K2K3K4K5K13K00
Effective Tax Rate %1.03%1%0.99%1%1%1%2.05%0.72%1.79%1%
Net Income+-24.4M-43.16M-51.51M-47.15M-53.24M-40.38M-35.1M42.52M-18.4M-13M
Net Margin %-1.27%-2.49%-6.44%-21.92%-23.26%-7.46%-92.85%--28.26%-
Net Income Growth %0.27%-0.77%-0.19%0.08%-0.13%0.24%0.13%2.21%-1.43%0.29%
Net Income (Continuing)-24.4M-43.16M-51.51M-47.15M-53.24M-40.38M-17.15M59.13M-10.29M-13M
Discontinued Operations000000-17.95M-11.37M-8.11M0
Minority Interest0000000000
EPS (Diluted)+-10.97-19.05-21.97-16.14-13.45-9.47-5.865.72-1.29-0.50
EPS Growth %0.27%-0.74%-0.15%0.27%0.17%0.3%0.38%1.98%-1.23%0.61%
EPS (Basic)-11.93-19.05-21.97-16.14-13.45-9.47-5.865.73-1.29-0.50
Diluted Shares Outstanding2.22M2.27M2.34M2.92M3.96M4.26M5.99M7.41M14.26M25.85M
Basic Shares Outstanding2.05M2.27M2.34M2.92M3.96M4.26M5.99M7.41M14.26M25.85M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+118.95M89.05M63.41M107.99M71.69M46.83M50.49M24.57M11.56M9.42M
Cash & Short-Term Investments113.46M80.31M60.47M105.72M66.14M42.89M46.63M15.77M9.38M8.86M
Cash Only107.92M80.31M52.9M87.97M14.68M27.27M7.66M15.28M5.72M8.86M
Short-Term Investments5.54M07.57M17.74M51.45M15.61M38.97M495K3.66M0
Accounts Receivable3.29M5.83M1.53M401K432K635K160K309K00
Days Sales Outstanding62.26122.6669.9968.0568.8942.79154.5---
Inventory466K2.15M956K854K3.29M1.63M1.11M1.18M00
Days Inventory Outstanding7.0163.8432.7478.4176.7198.39134.9261.06--
Other Current Assets00000002.31M-20K0
Total Non-Current Assets+8.84M10.94M12.14M12.54M19.67M19.46M27.4M22.92M8.84M8.82M
Property, Plant & Equipment8.61M10.71M11.05M11.48M18.48M18.81M20.23M13.86M00
Fixed Asset Turnover2.24x1.62x0.72x0.19x0.12x0.29x0.02x---
Goodwill0000000000
Intangible Assets00000008.82M8.82M0
Long-Term Investments0178K881K529K000000
Other Non-Current Assets228K50K207K527K1.19M656K7.17M246K20K8.82M
Total Assets+127.78M99.99M75.55M120.53M91.36M66.3M77.89M47.49M20.39M18.24M
Asset Turnover0.15x0.17x0.11x0.02x0.03x0.08x0.00x-0.03x-
Asset Growth %0.48%-0.22%-0.24%0.6%-0.24%-0.27%0.17%-0.39%-0.57%-0.11%
Total Current Liabilities+12.78M10.19M13.66M15.93M13.61M17.64M18.51M13.77M4.51M2.65M
Accounts Payable1.56M1.56M1.42M2.07M1.72M2.74M2.12M1.26M1.34M670K
Days Payables Outstanding23.4946.1848.76190.0392.24165.62257.54278.3587.9336.4
Short-Term Debt4.66M3.68M8.33M9M4.98M8.73M8.8M5.36M00
Deferred Revenue (Current)0362K362K315K0086K115K00
Other Current Liabilities2.6M2.56M2.19M3.61M411K155K2.97M2.8M1.17M723K
Current Ratio9.31x8.74x4.64x6.78x5.27x2.66x2.73x1.78x2.56x3.56x
Quick Ratio9.27x8.53x4.57x6.73x5.02x2.56x2.67x1.70x2.56x3.56x
Cash Conversion Cycle45.79140.3353.96-43.58153.35-24.4331.86---
Total Non-Current Liabilities+81.89M95.14M98.4M100.35M119.16M104.41M95.28M11.9M1.78M7.59M
Long-Term Debt79.88M90.86M94.35M96.67M112.2M13.14M5.01M006.53M
Capital Lease Obligations00003.64M2.61M3.75M2.96M00
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities2.02M455K585K537K3.32M88.66M85.37M7.91M1.78M1.06M
Total Liabilities94.67M105.33M112.06M116.28M132.77M122.05M113.79M25.67M6.29M10.24M
Total Debt+84.53M94.54M102.68M105.67M121.79M25.6M18.62M10.02M06.53M
Net Debt-23.39M14.23M49.78M17.7M107.11M-1.68M10.96M-5.25M-5.72M-2.34M
Debt / Equity2.55x--24.85x---0.46x-0.82x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage-3.55x-2.63x-2.76x-2.84x-21.38x-12.39x-7.91x-18.24x-126.04x-38.71x
Total Equity+33.11M-5.34M-36.51M4.25M-41.42M-55.75M-35.89M21.81M14.11M8M
Equity Growth %-0.29%-1.16%-5.84%1.12%-10.74%-0.35%0.36%1.61%-0.35%-0.43%
Book Value per Share14.89-2.36-15.571.46-10.46-13.08-5.992.950.990.31
Total Shareholders' Equity33.11M-5.34M-36.51M4.25M-41.42M-55.75M-35.89M21.81M14.11M8M
Common Stock45K45K51K78K79K98K7K8K17K17K
Retained Earnings-203.21M-246.36M-297.87M-345.02M-398.11M-438.49M-473.58M-425.83M-444.23M-457.23M
Treasury Stock0000000000
Accumulated OCI-1K3K00000000
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-19.95M-29.39M-29.77M-29.07M-51.18M-38.51M-30M-28.33M-17.49M-12.68M
Operating CF Margin %-1.04%-1.69%-3.72%-13.52%-22.36%-7.11%-79.37%--26.87%-
Operating CF Growth %0.42%-0.47%-0.01%0.02%-0.76%0.25%0.22%0.06%0.38%0.27%
Net Income-24.4M-43.16M-51.51M-47.15M-53.24M-40.38M-35.1M47.76M-18.4M-13M
Depreciation & Amortization1.98M2.05M1.74M575K1.67M1.85M1.97M1.65M311K-121K
Stock-Based Compensation5.01M4.48M4.29M5.17M5.06M4.42M4.61M2.89M1.73M989K
Deferred Taxes0000-11.84M712K810K02.2M0
Other Non-Cash Items1.87M22.76M14.96M14.74M11.08M-2.83M-2.5M-79.23M-1.79M-323K
Working Capital Changes-4.42M-2.27M3.7M1.87M-3.91M-2.29M203K-1.39M-1.54M-224K
Change in Receivables-3.29M-2.55M3.6M1.48M-31K-203K475K-149K-189K0
Change in Inventory-466K-1.69M920K102K-3.39M957K-295K-107K61K0
Change in Payables0-437K309K458K-19K1.02M111K551K-575K-671K
Cash from Investing+8.2M1.81M-9.97M-10.88M-36.56M34.14M-26.12M36.45M-528K3.78M
Capital Expenditures-1.46M-3.72M-2.4M-819K-3.47M-1.85M-1.83M-364K-100K0
CapEx % of Revenue0.08%0.21%0.3%0.38%1.52%0.34%4.83%-0.15%-
Acquisitions----------
Investments----------
Other Investing9.66M5.53M-7.57M-10.06M-33.09M35.99M0-1.69M2.72M0
Cash from Financing+59.63M-26K12.33M75.03M14.45M16.96M41.51M-507K3.47M12.04M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing64.17M-26K147K1.22M553K286K69K16K26K0
Net Change in Cash----------
Free Cash Flow+-21.41M-33.12M-32.17M-29.89M-54.65M-40.36M-31.83M-28.7M-17.59M-12.68M
FCF Margin %-1.11%-1.91%-4.02%-13.9%-23.88%-7.45%-84.2%--27.02%-
FCF Growth %0.46%-0.55%0.03%0.07%-0.83%0.26%0.21%0.1%0.39%0.28%
FCF per Share-9.63-14.62-13.72-10.24-13.80-9.47-5.31-3.87-1.23-0.49
FCF Conversion (FCF/Net Income)0.82x0.68x0.58x0.62x0.96x0.95x0.85x-0.67x0.95x0.98x
Interest Paid0001.67M000837K00
Taxes Paid0002K000000

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-61.17%-310.75%--1108.61%---194.9%-102.44%-117.65%
Return on Invested Capital (ROIC)-135.73%-257.52%-261.81%-152.16%-92.78%-743.43%--92.16%-101.55%-162.84%
Gross Margin-25.93%29.05%-33.32%-84.84%-197.34%-11.37%-695.24%--751.92%-
Net Margin-126.66%-248.64%-644.25%-2191.96%-2325.91%-745.55%-9285.45%--2825.96%-
Debt / Equity2.55x--24.85x---0.46x-0.82x
Interest Coverage-3.55x-2.63x-2.76x-2.84x-21.38x-12.39x-7.91x-18.24x-126.04x-38.71x
FCF Conversion0.82x0.68x0.58x0.62x0.96x0.95x0.85x-0.67x0.95x0.98x
Revenue Growth269.24%-9.89%-53.94%-73.1%6.42%136.61%-93.02%-100%--100%

Frequently Asked Questions

Growth & Financials

Talphera, Inc. (TLPH) reported $0.0M in revenue for fiscal year 2024. This represents a 97% decrease from $1.1M in 2011.

Talphera, Inc. (TLPH) saw revenue decline by 100.0% over the past year.

Talphera, Inc. (TLPH) reported a net loss of $12.4M for fiscal year 2024.

Dividend & Returns

Talphera, Inc. (TLPH) has a return on equity (ROE) of -117.7%. Negative ROE indicates the company is unprofitable.

Talphera, Inc. (TLPH) had negative free cash flow of $11.2M in fiscal year 2024, likely due to heavy capital investments.

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