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ESPREsperion Therapeutics, Inc.
$3.15$655M
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ESPR logoEsperion Therapeutics, Inc.(ESPR)Earnings, Financials & Key Ratios

ESPR•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustrySpecialty & Generic PharmaSub-IndustryTherapy-focused branded biopharma
AboutEsperion Therapeutics, Inc., a pharmaceutical company, develops and commercializes medicines for the treatment of patients with elevated low density lipoprotein cholesterol. Its lead product candidates are NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe) tablets for the treatment of patients with atherosclerotic cardiovascular disease or heterozygous familial hypercholesterolemia. The company has a license and collaboration agreement with Daiichi Sankyo Europe GmbH; and Serometrix to in-license its oral, small molecule PCSK9 inhibitor program. Esperion Therapeutics, Inc. was incorporated in 2008 and is headquartered in Ann Arbor, Michigan.Show more
  • Revenue$403M+21.3%
  • EBITDA$60M+10.9%
  • Net Income-$23M+56.2%
  • EPS (Diluted)-0.11+60.7%
  • Gross Margin67.95%-14.4%
  • EBITDA Margin14.98%-8.6%
  • Operating Margin14.95%-8.7%
  • Net Margin-5.63%+63.9%

ESPR Key Insights

Esperion Therapeutics, Inc. (ESPR) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y profit CAGR of 30.9%
  • ✓Strong 5Y sales CAGR of 12.1%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Shares diluted 11.0% in last year

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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ESPR Price & Volume

Esperion Therapeutics, Inc. (ESPR) stock price & volume — 10-year historical chart

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ESPR Growth Metrics

Esperion Therapeutics, Inc. (ESPR) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years12.12%
3 Years74.8%
TTM61.13%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM95.16%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM91.97%

Return on Capital

10 Years-55.74%
5 Years-37.82%
3 Years-10.6%
Last Year45.89%

ESPR Recent Earnings

Esperion Therapeutics, Inc. (ESPR) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 7/12 qtrs (58%)
Q2 2026Latest
May 8, 2026
Metric
Actual
Est
EPS
$0.10-150.0%
$0.04
Rev
$80M-5.2%
$85M
Q2 2026
May 7, 2026
Metric
Actual
Est
EPS
$0.01+75.0%
$0.04
Rev
$84M-1.1%
$85M
Q2 2026
Mar 10, 2026
Metric
Actual
Est
EPS
$0.22-4.3%
$0.23
Rev
$168M+1.2%
$166M
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.16-77.8%
$0.09
Rev
$87M-47.1%
$165M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 8, 2026
$0.10vs $0.04-150.0%
$80Mvs $85M-5.2%
Q2 2026May 7, 2026
$0.01vs $0.04+75.0%
$84Mvs $85M-1.1%
Q2 2026Mar 10, 2026
$0.22vs $0.23-4.3%
$168Mvs $166M+1.2%
Q4 2025Nov 6, 2025
$0.16vs $0.09-77.8%
$87Mvs $165M-47.1%
Based on last 12 quarters of dataView full earnings history →

ESPR Peer Comparison

Esperion Therapeutics, Inc. (ESPR) competitors in Therapy-focused branded biopharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
MDGL logoMDGLMadrigal Pharmaceuticals, Inc.Direct Competitor11.66B505.75-39.36432.05%-27.32%-50.15%0.59
EWTX logoEWTXEdgewise Therapeutics, Inc.Direct Competitor3.96B36.81-22.58-32.55%0.01
PRTA logoPRTAProthena Corporation plcDirect Competitor467.51M8.93-1.97-92.84%-260.92%-49.88%0.05
RARE logoRAREUltragenyx Pharmaceutical Inc.Direct Competitor2.7B27.44-4.7120.13%-91.03%-6.08%
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.7B21.629.4411.87%34.3%35.65%0.04
AMRN logoAMRNAmarin Corporation plcProduct Competitor333.42M16.03-8.91-6.55%-15.64%-7.34%0.03
AKRO logoAKROAkero Therapeutics, Inc.Product Competitor4.5B54.65-14.57-30.58%0.05
LNTH logoLNTHLantheus Holdings, Inc.Product Competitor6.76B103.8630.460.5%18.05%24.33%0.00

Compare ESPR vs Peers

Esperion Therapeutics, Inc. (ESPR) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs MDGL

Most directly comparable listed peer for ESPR.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ESPR against a more recognizable public peer.

Peer Set

Compare Top 5

vs MDGL, EWTX, PRTA, RARE

ESPR Income Statement

Esperion Therapeutics, Inc. (ESPR) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0184.47M148.36M227.55M78.45M75.47M116.33M332.31M403.13M418.24M
Revenue Growth %
---19.57%53.37%-65.52%-3.79%54.14%185.66%21.31%61.13%
Cost of Goods Sold
258K265K02.39M14.22M26.97M43.27M68.6M129.22M146.39M
COGS % of Revenue
-0.14%-1.05%18.12%35.73%37.19%20.64%32.05%-
Gross Profit
-258K▲ 0%
184.21M▲ 71498.8%
148.36M▼ 19.5%
225.16M▲ 51.8%
64.23M▼ 71.5%
48.51M▼ 24.5%
73.07M▲ 50.6%
263.71M▲ 260.9%
273.91M▲ 3.9%
271.85M▲ 0%
Gross Margin %
-99.86%100%98.95%81.88%64.27%62.81%79.36%67.95%65%
Gross Profit Growth %
-2.38%71498.84%-19.46%51.76%-71.47%-24.48%50.63%260.92%3.87%-
Operating Expenses
168.98M204.59M241.47M346.55M290.96M228.01M228.63M209.31M213.64M196.07M
OpEx % of Revenue
-110.9%162.75%152.3%370.9%302.1%196.53%62.99%52.99%-
Selling, General & Admin
21.38M33.1M65.85M199.62M184.99M109.08M142.52M163.07M165.79M165.91M
SG&A % of Revenue
-17.94%44.39%87.72%235.81%144.53%122.51%49.07%41.12%-
Research & Development
147.6M171.49M175.61M146.94M105.97M118.93M86.11M46.24M47.85M44.28M
R&D % of Revenue
-92.96%118.37%64.57%135.09%157.57%74.02%13.91%11.87%-
Other Operating Expenses
000000000-1000K
Operating Income
-168.98M▲ 0%
-204.59M▼ 21.1%
-93.1M▲ 54.5%
-121.4M▼ 30.4%
-226.73M▼ 86.8%
-179.5M▲ 20.8%
-155.56M▲ 13.3%
54.4M▲ 135.0%
60.27M▲ 10.8%
75.79M▲ 0%
Operating Margin %
--110.9%-62.75%-53.35%-289.02%-237.83%-133.72%16.37%14.95%18.12%
Operating Income Growth %
-121.91%-21.07%54.49%-30.39%-86.77%20.83%13.34%134.97%10.79%-
EBITDA
-168.72M-204.32M-92.78M-120.85M-226.12M-179M-155.4M54.47M60.38M75.89M
EBITDA Margin %
--110.76%-62.54%-53.11%-288.24%-237.17%-133.58%16.39%14.98%18.15%
EBITDA Growth %
-122.3%-21.1%54.59%-30.25%-87.11%20.84%13.19%135.05%10.86%290.33%
D&A (Non-Cash Add-back)
258K265K319K547K612K500K164K63K105K106K
EBIT
-166.79M-204.59M-89.05M-120.88M-222.75M-176.85M-150.27M7.51M60.27M77.13M
Net Interest Income
00-8.12M-22.67M-46.35M-56.81M-58.98M-59.25M-81.1M-44.27M
Interest Income
000000003.5M1.1M
Interest Expense
198K100K8.12M22.67M46.35M56.81M58.98M59.25M84.6M45.38M
Other Income/Expense
1.99M2.77M-4.06M-22.16M-42.38M-54.16M-53.69M-106.15M-81.11M-81.37M
Pretax Income
-166.99M▲ 0%
-201.81M▼ 20.9%
-97.17M▲ 51.9%
-143.55M▼ 47.7%
-269.11M▼ 87.5%
-233.66M▲ 13.2%
-209.25M▲ 10.4%
-51.74M▲ 75.3%
-20.84M▲ 59.7%
-5.58M▲ 0%
Pretax Margin %
--109.4%-65.49%-63.09%-343.04%-309.58%-179.87%-15.57%-5.17%-1.33%
Income Tax
000000001.84M1.84M
Effective Tax Rate %
0%0%0%0%0%0%0%0%-8.83%-32.98%
Net Income
-166.99M▲ 0%
-201.81M▼ 20.9%
-97.17M▲ 51.9%
-143.55M▼ 47.7%
-269.11M▼ 87.5%
-233.66M▲ 13.2%
-209.25M▲ 10.4%
-51.74M▲ 75.3%
-22.68M▲ 56.2%
-7.42M▲ 0%
Net Margin %
--109.4%-65.49%-63.09%-343.04%-309.58%-179.87%-15.57%-5.63%-1.77%
Net Income Growth %
-122.72%-20.85%51.85%-47.74%-87.47%13.17%10.45%75.27%56.17%95.16%
Net Income (Continuing)
-166.99M-201.81M-97.17M-143.55M-269.11M-233.66M-209.25M-51.74M-22.68M-7.42M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-6.98▲ 0%
-7.54▼ 8.0%
-4.02▲ 46.7%
-6.05▼ 50.5%
-11.03▼ 82.3%
-4.33▲ 60.7%
-2.03▲ 53.1%
-0.28▲ 86.2%
-0.11▲ 60.7%
-0.03▲ 0%
EPS Growth %
-109.61%-8.02%46.68%-50.5%-82.31%60.74%53.12%86.21%60.71%91.97%
EPS (Basic)
-6.98-7.54-4.02-6.05-11.03-4.33-2.03-0.28-0.11-
Diluted Shares Outstanding
23.93M26.75M27.09M27.47M28.9M66.41M103.11M187.18M207.87M251.35M
Basic Shares Outstanding
23.93M26.75M27.09M27.47M28.9M66.41M103.11M187.18M207.87M251.35M
Dividend Payout Ratio
----------

ESPR Balance Sheet

Esperion Therapeutics, Inc. (ESPR) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
203.92M142.63M211.71M345.9M328.97M246.68M201.06M338M167.85M459.46M
Cash & Short-Term Investments
34.47M36.97M200.78M304.96M259.33M166.86M82.25M144.76M167.85M156.16M
Cash Only
34.47M36.97M166.13M304.96M208.89M124.78M82.25M144.76M167.85M156.16M
Short-Term Investments
0034.65M050.44M42.09M0000
Accounts Receivable
00012.39M22.93M33.73M48.49M80.14M140.19M132.35M
Days Sales Outstanding
---19.87106.71163.11152.1588.02126.93108.93
Inventory
00016.14M34.39M35.2M65.62M94.49M105.12M104.21M
Days Inventory Outstanding
---2.46K883.01476.45553.6502.75296.93290.25
Other Current Assets
00928K011.17M9.87M4.51M18.02M-245.31M66.74M
Total Non-Current Assets
73.91M819K2.73M7.36M52.62M1.26M4.73M5.82M298.03M3.07M
Property, Plant & Equipment
435K520K2.68M7.31M2.56M1.2M4.67M5.77M3.26M3.01M
Fixed Asset Turnover
-354.76x55.42x31.15x30.62x62.90x24.88x57.62x123.66x117.77x
Goodwill
0000000000
Intangible Assets
56K56K56K56K0056K56K56K56K
Long-Term Investments
239.15M99.29M00000000
Other Non-Current Assets
-165.73M-99.05M0050M000-123.13M0
Total Assets
277.83M▲ 0%
143.45M▼ 48.4%
214.45M▲ 49.5%
353.26M▲ 64.7%
381.59M▲ 8.0%
247.94M▼ 35.0%
205.8M▼ 17.0%
343.82M▲ 67.1%
465.89M▲ 35.5%
462.53M▲ 0%
Asset Turnover
-1.29x0.69x0.64x0.21x0.30x0.57x0.97x0.87x1.02x
Asset Growth %
13.3%-48.37%49.49%64.73%8.02%-35.02%-17%67.07%35.5%92.65%
Total Current Liabilities
33.14M64.33M66.08M94.07M73.35M92.31M156.22M246.23M300.81M300.36M
Accounts Payable
20.38M44.89M28.86M51.98M17.56M23.04M31.72M51.65M65.07M68.41M
Days Payables Outstanding
28.83K61.83K-7.93K450.8311.85267.57274.81183.79178.08
Short-Term Debt
1.04M0000034.83M102.16M89.7M1.7M
Deferred Revenue (Current)
38K02.15M1.66M5.68M3.51M25.4M8.52M043.53M
Other Current Liabilities
10.99M1.88M7.82M15.16M8.81M9.05M49.24M12.74M146.04M186.72M
Current Ratio
6.15x2.22x3.20x3.68x4.48x2.67x1.29x1.37x0.56x1.53x
Quick Ratio
6.15x2.22x3.20x3.51x4.02x2.29x0.87x0.99x0.21x1.18x
Cash Conversion Cycle
----5.45K538.92327.71438.17315.97240.07221.09
Total Non-Current Liabilities
00128.42M355.32M505.18M479.41M504.57M486.31M467.04M470.1M
Long-Term Debt
000179.37M258.28M259.9M501.55M483.74M457.65M250.93M
Capital Lease Obligations
001.11M3.45M524K665K3.02M2.57M653K3.59M
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
00127.31M172.5M245.74M218.84M008.74M219.17M
Total Liabilities
33.14M64.33M194.5M449.39M578.53M571.72M660.79M732.54M767.85M770.46M
Total Debt
1.04M01.56M185.41M260.2M260.95M540.95M591.21M548M252.63M
Net Debt
-33.42M-36.97M-164.57M-119.55M51.3M136.17M458.7M446.45M380.15M96.47M
Debt / Equity
0.00x-0.08x-------0.82x
Debt / EBITDA
-------10.85x9.08x3.33x
Net Debt / EBITDA
-------8.20x6.30x1.27x
Interest Coverage
-842.37x-2045.85x-10.97x-5.33x-4.81x-3.11x-2.55x0.13x0.71x1.70x
Total Equity
244.69M▲ 0%
-598.1M▼ 344.4%
19.95M▲ 103.3%
-96.13M▼ 581.9%
-196.94M▼ 104.9%
-323.78M▼ 64.4%
-454.99M▼ 40.5%
-388.72M▲ 14.6%
-301.96M▲ 22.3%
-307.93M▲ 0%
Equity Growth %
7.04%-344.43%103.34%-581.87%-104.86%-64.4%-40.53%14.57%22.32%2.21%
Book Value per Share
10.22-22.360.74-3.50-6.81-4.88-4.41-2.08-1.45-1.23
Total Shareholders' Equity
244.69M-598.1M19.95M-96.13M-196.94M-323.78M-454.99M-388.72M-301.96M-307.93M
Common Stock
26K27K27K26K61K75K118K196K245K257K
Retained Earnings
-396.29M-598.1M-695.27M-838.82M-1.11B-1.34B-1.55B-1.6B-1.62B-1.65B
Treasury Stock
000-55M-55M-55M-55M-55M-55M-55M
Accumulated OCI
-845K-319K23K0-31K-2K0000
Minority Interest
0000000000

ESPR Cash Flow Statement

Esperion Therapeutics, Inc. (ESPR) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-131.3M-148.64M-70.34M-85.18M-263.81M-174.83M-135.49M-23.65M-13.09M-18.19M
Operating CF Margin %
--80.57%-47.41%-37.43%-336.29%-231.64%-116.46%-7.12%-3.25%-
Operating CF Growth %
-175.09%-13.2%52.68%-21.09%-209.72%33.73%22.5%82.54%44.65%-41.32%
Net Income
-166.99M-201.81M-97.17M-143.55M-269.11M-233.66M-209.25M-51.74M-22.68M-7.42M
Depreciation & Amortization
258K265K319K547K612K500K164K63K105K2.35M
Stock-Based Compensation
18.61M23.97M25.88M28.39M24.31M15.21M11.96M11.99M9.87M7.41M
Deferred Taxes
334K00-97K000000
Other Non-Cash Items
23K-217K7.92M33.8M32.89M46.49M47.96M76.56M14.26M18.47M
Working Capital Changes
16.47M29.16M-7.3M-4.26M-52.51M-3.37M13.68M-60.53M-14.64M-38.99M
Change in Receivables
000-10.74M-10.55M-10.79M-14.77M-31.65M-60.05M-51.06M
Change in Inventory
000-16.14M-18.26M-807K-30.42M-28.87M-10.63M-4.89M
Change in Payables
15.76M24.45M-16.05M23.11M-34.1M5.6M8.68M12.43M20.92M-6.49M
Cash from Investing
-35.85M140.45M64.23M21.36M-50.48M8.1M42.5M-317K00
Capital Expenditures
-19K-151K-953K-13.37M000-317K00
CapEx % of Revenue
-0.08%0.64%5.88%---0.1%-0%
Acquisitions
00012.5M000000
Investments
----------
Other Investing
-35.83M140.6M0-12.5M000000
Cash from Financing
163.46M10.69M136.19M201.72M268.22M32.61M50.46M86.48M36.18M59.9M
Debt Issued (Net)
-1.71M-1.05M0271.6M-440K0035.01M-54.91M-54.91M
Equity Issued (Net)
164M00-55M218.69M90.85M56.88M91.19M98.35M103.9M
Dividends Paid
0000000000
Share Repurchases
000-55M000000
Other Financing
1.17M11.74M136.19M-14.87M49.98M-58.24M-6.42M-39.72M-7.26M10.92M
Net Change in Cash
-3.7M▲ 0%
2.5M▲ 167.8%
130.09M▲ 5093.0%
137.9M▲ 6.0%
-46.07M▼ 133.4%
-134.12M▼ 191.1%
-42.53M▲ 68.3%
62.51M▲ 247.0%
23.09M▼ 63.1%
41.52M▲ 0%
Free Cash Flow
-131.32M▲ 0%
-148.79M▼ 13.3%
-71.29M▲ 52.1%
-98.55M▼ 38.2%
-263.81M▼ 167.7%
-174.83M▲ 33.7%
-135.49M▲ 22.5%
-23.97M▲ 82.3%
-13.09M▲ 45.4%
-18.19M▲ 0%
FCF Margin %
--80.66%-48.05%-43.31%-336.29%-231.64%-116.46%-7.21%-3.25%-4.35%
FCF Growth %
-174.59%-13.3%52.08%-38.22%-167.7%33.73%22.5%82.31%45.38%81.88%
FCF per Share
-5.49-5.56-2.63-3.59-9.13-2.63-1.31-0.13-0.06-0.07
FCF Conversion (FCF/Net Income)
0.79x0.74x0.72x0.59x0.98x0.75x0.65x0.46x0.58x2.45x
Interest Paid
0000000016.27M0
Taxes Paid
00000000612K0

ESPR Key Ratios

Esperion Therapeutics, Inc. (ESPR) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-70.56%--487.04%------1.99%
Return on Invested Capital (ROIC)
-62.67%------132.83%66.52%9069.17%
Gross Margin
-99.86%100%98.95%81.88%64.27%62.81%79.36%67.95%65%
Net Margin
--109.4%-65.49%-63.09%-343.04%-309.58%-179.87%-15.57%-5.63%-1.77%
Debt / Equity
0.00x-0.08x-------0.82x
Interest Coverage
-842.37x-2045.85x-10.97x-5.33x-4.81x-3.11x-2.55x0.13x0.71x1.70x
FCF Conversion
0.79x0.74x0.72x0.59x0.98x0.75x0.65x0.46x0.58x2.45x
Revenue Growth
---19.57%53.37%-65.52%-3.79%54.14%185.66%21.31%61.13%
Related:ESPR Dividend History·ESPR Revenue History·ESPR Price History·ESPR P/E History·ESPR Financial Ratios·ESPR Institutional Holders

ESPR SEC Filings & Documents

Esperion Therapeutics, Inc. (ESPR) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 1, 2026·SEC

Material company update

Apr 2, 2026·SEC

Material company update

Mar 10, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 10, 2026·SEC

FY 2025

Mar 7, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 8, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 13, 2025·SEC

ESPR Frequently Asked Questions

Esperion Therapeutics, Inc. (ESPR) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Esperion Therapeutics, Inc. (ESPR) reported $418.2M in revenue for fiscal year 2025.

Esperion Therapeutics, Inc. (ESPR) grew revenue by 21.3% over the past year. This is strong growth.

Esperion Therapeutics, Inc. (ESPR) reported a net loss of $7.4M for fiscal year 2025.

Dividend & Returns

Esperion Therapeutics, Inc. (ESPR) had negative free cash flow of $18.2M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ESPR back in 1999?

Total return calculator · dividends reinvested · 27+ years of data

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How much would $100/month in ESPR be worth today?

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