Comprehensive Stock Comparison

Compare Merck & Co., Inc. (MRK) vs Johnson & Johnson (JNJ) Stock

Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.

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Quick Verdict

CategoryWinnerWhy
GrowthJNJ4.3% revenue growth vs MRK's 1.3%
ValueMRKPEG 1.13 vs 38.22
Quality / MarginsMRK28.1% net margin vs JNJ's 27.3%
Stability / SafetyJNJBeta 0.06 vs MRK's 0.43
DividendsJNJ2.0% yield; 36-year raise streak; MRK pays no meaningful dividend
Momentum (1Y)JNJ+53.7% vs MRK's +37.7%
Bottom line: JNJ leads in 4 of 6 categories, making it the stronger pick for investors who prioritize growth and revenue expansion and capital preservation and lower volatility. Merck & Co., Inc. is the better choice for valuation and capital efficiency and profitability and margin quality. As direct sector peers, they can serve as alternatives in the same portfolio allocation.

Who Each Stock Is For

Income & stability

Growth exposure

Long-term compounding (10Y)

Sleep-well-at-night portfolio

Valuation efficiency (growth/$)

Defensive / Recession hedge

Business Model

What each company does and how it makes money

MRKMerck & Co., Inc.
Healthcare

Merck & Co. is a global pharmaceutical company that develops and markets prescription medicines, vaccines, and animal health products. It generates revenue primarily from its Pharmaceutical segment — including blockbuster cancer drug Keytruda — which accounts for roughly 90% of sales, with the remaining 10% coming from Animal Health products. The company's key competitive advantage lies in its deep oncology franchise, particularly Keytruda's dominant position in immuno-oncology, supported by extensive clinical data and patent protection.

JNJJohnson & Johnson
Healthcare

Johnson & Johnson is a global healthcare company focused on innovative medicines and medical technology. It generates revenue primarily from its Innovative Medicine segment — prescription drugs for complex diseases like cancer and autoimmune disorders — and its MedTech segment — medical devices including orthopedics, surgery tools, and contact lenses. The company's competitive advantage lies in its massive R&D scale, deep scientific expertise, and diversified portfolio of patented pharmaceuticals and medical devices.

Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MRKMerck & Co., Inc.
FY 2024
Pharmaceutical segment
89.5%$57.4B
Animal Health segment
9.2%$5.9B
Other Segments
1.4%$891M
JNJJohnson & Johnson
FY 2024
Innovative Medicine
64.1%$57.0B
MedTech
35.9%$31.9B

Financial Metrics Comparison

Side-by-side fundamentals across 2 stocks. BestLagging

Financial Scorecard

JNJ 3MRK 2
Financial MetricsTie3/6 metrics
Valuation MetricsMRK5/6 metrics
Profitability & EfficiencyMRK4/6 metrics
Total ReturnsJNJ4/6 metrics
Risk & VolatilityJNJ2/2 metrics
Analyst OutlookJNJ1/1 metrics

JNJ leads in 3 of 6 categories (Total Returns, Risk & Volatility). MRK leads in 2 (Valuation Metrics, Profitability & Efficiency). 1 tied.

Financial Metrics (TTM)

JNJ and MRK operate at a comparable scale, with $92.1B and $65.0B in trailing revenue. Profitability is closely matched — net margins range from 28.1% (MRK) to 27.3% (JNJ).

MetricMRKMerck & Co., Inc.JNJJohnson & Johnson
RevenueTrailing 12 months$65.0B$92.1B
EBITDAEarnings before interest/tax$31.1B$31.4B
Net IncomeAfter-tax profit$18.3B$25.1B
Free Cash FlowCash after capex$10.5B$19.1B
Gross MarginGross profit ÷ Revenue+81.5%+68.1%
Operating MarginEBIT ÷ Revenue+41.2%+26.1%
Net MarginNet income ÷ Revenue+28.1%+27.3%
FCF MarginFCF ÷ Revenue+16.2%+20.7%
Rev. Growth (YoY)Latest quarter vs prior year+5.0%+6.8%
EPS Growth (YoY)Latest quarter vs prior year-19.6%+91.0%
Evenly matched — MRK and JNJ each lead in 3 of 6 comparable metrics.

Valuation Metrics

At 17.0x trailing earnings, MRK trades at a 60% valuation discount to JNJ's 42.9x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.80x vs JNJ's 38.22x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMRKMerck & Co., Inc.JNJJohnson & Johnson
Market CapShares × price$307.2B$598.7B
Enterprise ValueMkt cap + debt − cash$307.2B$611.2B
Trailing P/EPrice ÷ TTM EPS17.00x42.91x
Forward P/EPrice ÷ next-FY EPS est.24.05x21.48x
PEG RatioP/E ÷ EPS growth rate0.80x38.22x
EV / EBITDAEnterprise value multiple9.89x20.73x
Price / SalesMarket cap ÷ Revenue4.73x6.74x
Price / BookPrice ÷ Book value/share5.98x8.44x
Price / FCFMarket cap ÷ FCF30.17x
MRK leads this category, winning 5 of 6 comparable metrics.

Profitability & Efficiency

MRK delivers a 35.2% return on equity — every $100 of shareholder capital generates $35 in annual profit, vs $32 for JNJ. On the Piotroski fundamental quality scale (0–9), JNJ scores 5/9 vs MRK's 2/9, reflecting solid financial health.

MetricMRKMerck & Co., Inc.JNJJohnson & Johnson
ROE (TTM)Return on equity+35.2%+31.7%
ROA (TTM)Return on assets+13.0%
ROICReturn on invested capital+32.6%+20.7%
ROCEReturn on capital employed+17.6%
Piotroski ScoreFundamental quality 0–925
Debt / EquityFinancial leverage0.51x
Net DebtTotal debt minus cash$0$12.5B
Cash & Equiv.Liquid assets$24.1B
Total DebtShort + long-term debt$0$36.6B
Interest CoverageEBIT ÷ Interest expense25.93x48.23x
MRK leads this category, winning 4 of 6 comparable metrics.

Total Returns (with DRIP)

A $10,000 investment in MRK five years ago would be worth $20,074 today (with dividends reinvested), compared to $17,079 for JNJ. Over the past 12 months, JNJ leads with a +53.7% total return vs MRK's +37.7%. The 3-year compound annual growth rate (CAGR) favors JNJ at 19.8% vs MRK's 7.8% — a key indicator of consistent wealth creation.

MetricMRKMerck & Co., Inc.JNJJohnson & Johnson
YTD ReturnYear-to-date+16.3%+20.4%
1-Year ReturnPast 12 months+37.7%+53.7%
3-Year ReturnCumulative with dividends+25.3%+71.8%
5-Year ReturnCumulative with dividends+100.7%+70.8%
10-Year ReturnCumulative with dividends+210.2%+175.7%
CAGR (3Y)Annualised 3-year return+7.8%+19.8%
JNJ leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

JNJ is the less volatile stock with a 0.06 beta — it tends to amplify market swings less than MRK's 0.43 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.

MetricMRKMerck & Co., Inc.JNJJohnson & Johnson
Beta (5Y)Sensitivity to S&P 5000.43x0.06x
52-Week HighHighest price in past year$125.14$248.93
52-Week LowLowest price in past year$73.31$141.50
% of 52W HighCurrent price vs 52-week peak+98.9%+99.8%
RSI (14)Momentum oscillator 0–10056.066.2
Avg Volume (50D)Average daily shares traded10.8M7.1M
JNJ leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Wall Street rates MRK as "Buy" and JNJ as "Buy". Consensus price targets imply 0.1% upside for MRK (target: $124) vs -7.7% for JNJ (target: $229). JNJ is the only dividend payer here at 1.96% yield — a key consideration for income-focused portfolios.

MetricMRKMerck & Co., Inc.JNJJohnson & Johnson
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$123.92$229.33
# AnalystsCovering analysts3639
Dividend YieldAnnual dividend ÷ price+2.0%
Dividend StreakConsecutive years of raises1336
Dividend / ShareAnnual DPS$4.87
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.4%
JNJ leads this category, winning 1 of 1 comparable metric.

Historical Charts

Charts are rendered on first load. Hover for details.

Chart 1Total Return — 5 Years (Rebased to 100)

StockMar 20Feb 26Change
Merck & Co., Inc. (MRK)100146.11+46.1%
Johnson & Johnson (JNJ)100164.8+64.8%

Merck & Co., Inc. (MRK) returned +101% over 5 years vs Johnson & Johnson (JNJ)'s +71%. A $10,000 investment in MRK 5 years ago would be worth $20,074 today (including dividends reinvested).

Chart 2Revenue Growth — 10 Years

Stock20162025Change
Merck & Co., Inc. (MRK)$39.8B$65.0B+63.3%
Johnson & Johnson (JNJ)$71.9B$88.8B+23.6%

Merck & Co., Inc.'s revenue grew from $39.8B (2016) to $65.0B (2025) — a 5.6% CAGR.

Chart 3Net Margin Trend — 10 Years

Stock20162025Change
Merck & Co., Inc. (MRK)9.8%28.1%+185.1%
Johnson & Johnson (JNJ)23.0%15.8%-31.2%

Merck & Co., Inc.'s net margin went from 10% (2016) to 28% (2025).

Chart 4P/E Ratio History — 9 Years

Stock20172025Change
Merck & Co., Inc. (MRK)57.714.5-74.9%
Johnson & Johnson (JNJ)297.325-91.6%

Merck & Co., Inc. has traded in a 15x–58x P/E range over 8 years; current trailing P/E is ~17x. Johnson & Johnson has traded in a 11x–297x P/E range over 8 years; current trailing P/E is ~43x.

Chart 5EPS Growth — 10 Years

Stock20162025Change
Merck & Co., Inc. (MRK)2.047.28+256.9%
Johnson & Johnson (JNJ)5.935.79-2.4%

Merck & Co., Inc.'s EPS grew from $2.04 (2016) to $7.28 (2025) — a 15% CAGR.

Chart 6Free Cash Flow — 5 Years

2021
$10B
$20B
2022
$15B
$17B
2023
$9B
$18B
2024
$18B
$20B
2025
$0M
Merck & Co., Inc. (MRK)Johnson & Johnson (JNJ)

Merck & Co., Inc. generated $0M FCF in 2025 (-100% vs 2021). Johnson & Johnson generated $20B FCF in 2024 (+0% vs 2021).

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MRK vs JNJ: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is MRK or JNJ a better buy right now?

Merck & Co., Inc. (MRK) offers the better valuation at 17.0x trailing P/E (24.0x forward), making it the more compelling value choice. Analysts rate Merck & Co., Inc. (MRK) a "Buy" — based on 36 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MRK or JNJ?

On trailing P/E, Merck & Co., Inc. (MRK) is the cheapest at 17.0x versus Johnson & Johnson at 42.9x. On forward P/E, Johnson & Johnson is actually cheaper at 21.5x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Merck & Co., Inc. wins at 1.13x versus Johnson & Johnson's 38.22x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — MRK or JNJ?

Over the past 5 years, Merck & Co., Inc. (MRK) delivered a total return of +100.7%, compared to +70.8% for Johnson & Johnson (JNJ). A $10,000 investment in MRK five years ago would be worth approximately $20K today (assuming dividends reinvested). Over 10 years, the gap is even starker: MRK returned +210.2% versus JNJ's +175.7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MRK or JNJ?

By beta (market sensitivity over 5 years), Johnson & Johnson (JNJ) is the lower-risk stock at 0.06β versus Merck & Co., Inc.'s 0.43β — meaning MRK is approximately 674% more volatile than JNJ relative to the S&P 500.

05

Which has better profit margins — MRK or JNJ?

Merck & Co., Inc. (MRK) is the more profitable company, earning 28.1% net margin versus 15.8% for Johnson & Johnson — meaning it keeps 28.1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 41.2% versus 24.9% for JNJ. At the gross margin level — before operating expenses — MRK leads at 81.5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is MRK or JNJ more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential. By this metric, Merck & Co., Inc. (MRK) is the more undervalued stock at a PEG of 1.13x versus Johnson & Johnson's 38.22x. A PEG below 1.5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Johnson & Johnson (JNJ) trades at 21.5x forward P/E versus 24.0x for Merck & Co., Inc. — 2.6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MRK: 0.1% to $123.92.

07

Which pays a better dividend — MRK or JNJ?

In this comparison, JNJ (2.0% yield) pays a dividend. MRK does not pay a meaningful dividend and should not be held primarily for income.

08

Is MRK or JNJ better for a retirement portfolio?

For long-horizon retirement investors, Johnson & Johnson (JNJ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.06), 2.0% yield, +175.7% 10Y return). Both have compounded well over 10 years (JNJ: +175.7%, MRK: +210.2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between MRK and JNJ?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both. In terms of investment character: MRK is a large-cap deep-value stock; JNJ is a large-cap quality compounder stock. JNJ pays a dividend while MRK does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
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Better Than Both

Find stocks that beat MRK and JNJ on the metrics you choose

Revenue Growth>
%
(MRK: 5.0% · JNJ: 6.8%)
Net Margin>
%
(MRK: 28.1% · JNJ: 27.3%)
P/E Ratio<
x
(MRK: 17.0x · JNJ: 42.9x)